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Items: 1 to 20 of 35

1.
Exploring the activation mechanism of metabotropic glutamate receptor 2
Xiaohong Zhu, Mengqi Luo, Ke An, Danfeng Shi, Tingjun Hou, Arieh Warshel, Chen Bai
Proc Natl Acad Sci U S A. 2024 May 21; 121(21): e2401079121. Published online 2024 May 13. doi: 10.1073/pnas.2401079121
PMCID:
PMC11126994
AbstractArticlePDF–3.2M
2.
Heterodimerization of Chemoreceptors TAS1R3 and mGlu2 in Human Blood Leukocytes
Lena Ball, Julia Bauer, Dietmar Krautwurst
Int J Mol Sci. 2023 Aug; 24(16): 12942. Published online 2023 Aug 18. doi: 10.3390/ijms241612942
PMCID:
PMC10454557
AbstractArticlePDF–3.0M
3.
The crosstalk between 5-HT2AR and mGluR2 in schizophrenia
Somdatta Saha, Javier González-Maeso
Neuropharmacology. Author manuscript; available in PMC 2024 Jun 1.
Published in final edited form as: Neuropharmacology. 2023 Jun 1; 230: 109489. Published online 2023 Mar 6. doi: 10.1016/j.neuropharm.2023.109489
PMCID:
PMC10103009
AbstractArticlePDF–1.6M
4.
Transferrin Receptor Protein 1 Cooperates with mGluR2 To Mediate the Internalization of Rabies Virus and SARS-CoV-2
Xinxin Wang, Zhiyuan Wen, Huizhen Cao, Jie Luo, Lei Shuai, Chong Wang, Jinying Ge, Xijun Wang, Zhigao Bu, Jinliang Wang
J Virol. 2023 Feb; 97(2): e01611-22. Published online 2023 Feb 13. doi: 10.1128/jvi.01611-22
PMCID:
PMC9972945
AbstractArticlePDF–3.0M
5.
G-protein activation by a metabotropic glutamate receptor
Alpay B. Seven, Ximena Barros-Álvarez, Marine de Lapeyrière, Makaía M. Papasergi-Scott, Michael J. Robertson, Chensong Zhang, Robert M. Nwokonko, Yang Gao, Justin G. Meyerowitz, Jean-Philippe Rocher, Dominik Schelshorn, Brian K. Kobilka, Jesper M. Mathiesen, Georgios Skiniotis
Nature. Author manuscript; available in PMC 2022 Jul 1.
Published in final edited form as: Nature. 2021 Jul; 595(7867): 450–454. Published online 2021 Jun 30. doi: 10.1038/s41586-021-03680-3
PMCID:
PMC8822903
AbstractArticlePDF–5.5M
6.
SARS-CoV-2 uses metabotropic glutamate receptor subtype 2 as an internalization factor to infect cells
Jinliang Wang, Guan Yang, Xinxin Wang, Zhiyuan Wen, Lei Shuai, Jie Luo, Chong Wang, Ziruo Sun, Renqiang Liu, Jinying Ge, Xijun He, Ronghong Hua, Xijun Wang, Xiao Yang, Weiye Chen, Gongxun Zhong, Zhigao Bu
Cell Discov. 2021; 7: 119. Published online 2021 Dec 14. doi: 10.1038/s41421-021-00357-z
Correction in:
Cell Discov. 2021; 7: 124.
PMCID:
PMC8668938
AbstractArticlePDF–3.9M
7.
Allosteric modulators enhance agonist efficacy by increasing the residence time of a GPCR in the active state
Anne-Marinette Cao, Robert B. Quast, Fataneh Fatemi, Philippe Rondard, Jean-Philippe Pin, Emmanuel Margeat
Nat Commun. 2021; 12: 5426. Published online 2021 Sep 14. doi: 10.1038/s41467-021-25620-5
PMCID:
PMC8440590
AbstractArticlePDF–3.6M
8.
Conformational rearrangement during activation of a metabotropic glutamate receptor
Brandon Wey-Hung Liauw, Hamid Samareh Afsari, Reza Vafabakhsh
Nat Chem Biol. Author manuscript; available in PMC 2021 Jul 4.
Published in final edited form as: Nat Chem Biol. 2021 Mar; 17(3): 291–297. Published online 2021 Jan 4. doi: 10.1038/s41589-020-00702-5
PMCID:
PMC7904630
AbstractArticlePDF–5.1M
9.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
10.
The midbody interactome reveals unexpected roles for PP1 phosphatases in cytokinesis
Luisa Capalbo, Zuni I. Bassi, Marco Geymonat, Sofia Todesca, Liviu Copoiu, Anton J. Enright, Giuliano Callaini, Maria Giovanna Riparbelli, Lu Yu, Jyoti S. Choudhary, Enrico Ferrero, Sally Wheatley, Max E. Douglas, Masanori Mishima, Pier Paolo D’Avino
Nat Commun. 2019; 10: 4513. Published online 2019 Oct 4. doi: 10.1038/s41467-019-12507-9
PMCID:
PMC6778137
AbstractArticlePDF–7.8M
11.
Tamalin, a PDZ Domain-Containing Protein, Links a Protein Complex Formation of Group 1 Metabotropic Glutamate Receptors and the Guanine Nucleotide Exchange Factor Cytohesins
Jun Kitano, Kouji Kimura, Yoshimitsu Yamazaki, Takeshi Soda, Ryuichi Shigemoto, Yoshiaki Nakajima, Shigetada Nakanishi
J Neurosci. 2002 Feb 15; 22(4): 1280–1289. doi: 10.1523/JNEUROSCI.22-04-01280.2002
PMCID:
PMC6757580
AbstractArticlePDF–529K
12.
Synergistic drug combinations for cancer identified in a CRISPR screen for pairwise genetic interactions
Kyuho Han, Edwin E. Jeng, Gaelen T. Hess, David W. Morgens, Amy Li, Michael C. Bassik
Nat Biotechnol. Author manuscript; available in PMC 2017 Sep 20.
Published in final edited form as: Nat Biotechnol. 2017 May; 35(5): 463–474. Published online 2017 Mar 20. doi: 10.1038/nbt.3834
PMCID:
PMC5557292
AbstractArticlePDF–3.4M
13.
Group II Metabotropic Glutamate Receptor Interactions with NHERF Scaffold Proteins: Implications for Receptor Localization in Brain
Stefanie L. Ritter-Makinson, Maryse Paquet, James W. Bogenpohl, Rachel E. Rodin, C. Chris Yun, Edward J. Weinman, Yoland Smith, Randy A. Hall
Neuroscience. Author manuscript; available in PMC 2018 Jun 14.
Published in final edited form as: Neuroscience. 2017 Jun 14; 353: 58–75. Published online 2017 Apr 7. doi: 10.1016/j.neuroscience.2017.03.060
PMCID:
PMC5503475
AbstractArticlePDF–1.0M
14.
Group II mGluRs suppress hyperexcitability in mouse and human nociceptors
Steve Davidson, Judith P. Golden, Bryan A. Copits, Pradipta R. Ray, Sherri K. Vogt, Manouela V. Valtcheva, Robert E. Schmidt, Andrea Ghetti, Theodore Price, Robert W. Gereau, IV
Pain. Author manuscript; available in PMC 2017 Sep 1.
Published in final edited form as: Pain. 2016 Sep; 157(9): 2081–2088. doi: 10.1097/j.pain.0000000000000621
PMCID:
PMC4988887
AbstractArticlePDF–1.7M
15.
Allosteric signaling through an mGlu2 and 5-HT2A heteromeric receptor complex and its potential contribution to schizophrenia
José L. Moreno, Patricia Miranda-Azpiazu, Aintzane García-Bea, Jason Younkin, Meng Cui, Alexey Kozlenkov, Ariel Ben-Ezra, Georgios Voloudakis, Amanda K. Fakira, Lia Baki, Yongchao Ge, Anastasios Georgakopoulos, José A. Morón, Graeme Milligan, Juan F. López-Giménez, Nikolaos K. Robakis, Diomedes E. Logothetis, J. Javier Meana, Javier González-Maeso
Sci Signal. Author manuscript; available in PMC 2017 Jan 12.
Published in final edited form as: Sci Signal. 2016; 9(410): ra5. Published online 2016 Jan 12. doi: 10.1126/scisignal.aab0467
PMCID:
PMC4819166
AbstractArticlePDF–1.0M
16.
Molecular mechanism of positive allosteric modulation of the metabotropic glutamate receptor 2 by JNJ‐46281222
Maarten L J Doornbos, Laura Pérez‐Benito, Gary Tresadern, Thea Mulder‐Krieger, Ilse Biesmans, Andrés A Trabanco, Jose María Cid, Hilde Lavreysen, Adriaan P IJzerman, Laura H Heitman
Br J Pharmacol. 2016 Feb; 173(3): 588–600. Published online 2016 Jan 13. doi: 10.1111/bph.13390
PMCID:
PMC4728424
AbstractArticlePDF–1.5M
17.
Molecular determinants of positive allosteric modulation of the human metabotropic glutamate receptor 2
A Farinha, H Lavreysen, L Peeters, B Russo, S Masure, A A Trabanco, J Cid, G Tresadern
Br J Pharmacol. 2015 May; 172(9): 2383–2396. Published online 2015 Feb 27. doi: 10.1111/bph.13065
PMCID:
PMC4403101
AbstractArticlePDF–1.0M
18.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
19.
Metabotropic glutamate receptor mGluR2/3 and mGluR5 binding in the anterior cingulate cortex in psychotic and nonpsychotic depression, bipolar disorder and schizophrenia: implications for novel mGluR-based therapeutics
Natalie Matosin, Francesca Fernandez-Enright, Elisabeth Frank, Chao Deng, Jenny Wong, Xu-Feng Huang, Kelly A. Newell
J Psychiatry Neurosci. 2014 Nov; 39(6): 407–416. Prepublished online 2014 Jun 24. doi: 10.1503/jpn.130242
PMCID:
PMC4214875
AbstractArticlePDF–546K
20.
Systematic identification of pathological lamin A interactors
Travis A. Dittmer, Nidhi Sahni, Nard Kubben, David E. Hill, Marc Vidal, Rebecca C. Burgess, Vassilis Roukos, Tom Misteli
Mol Biol Cell. 2014 May 1; 25(9): 1493–1510. doi: 10.1091/mbc.E14-02-0733
PMCID:
PMC4004598
AbstractArticlePDF–3.5M

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