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Select item 100332251.

Concomitant genetic defects potentiate the adverse impact of prenatal alcohol exposure on cardiac outflow tract maturation

Drayton C. Harvey, Prashan De Zoysa, Omar Toubat, Jongkyu Choi, Jahnavi Kishore, Hidekazu Tsukamoto, S. Ram Kumar

Birth Defects Res. Author manuscript; available in PMC 2023 Mar 23.

Published in final edited form as: Birth Defects Res. 2022 Feb; 114(3-4): 105–115. Published online 2021 Dec 3. doi: 10.1002/bdr2.1968

PMCID:: PMC10033225

Abstract Article PDF–1.6M

Select item 99264952.

Delivery of VEGF and delta-like 4 to synergistically regenerate capillaries and arterioles in ischemic limbs

Hong Niu, Ning Gao, Yu Dang, Ya Guan, Jianjun Guan

Acta Biomater. Author manuscript; available in PMC 2023 Feb 14.

Published in final edited form as: Acta Biomater. 2022 Apr 15; 143: 295–309. Published online 2022 Mar 14. doi: 10.1016/j.actbio.2022.03.021

PMCID:: PMC9926495

Abstract Article PDF–3.0M

Select item 86651003.

Reduced Notch1 cleavage promotes the development of pulmonary hypertension

Shumin Wang, Guofu Zhu, Dongyang Jiang, Jordan Rhen, Xiankai Li, Hao Liu, Yuyan Lyu, Patrick Tsai, Yara Rose, Tiffany Nguyen, R. James White, Gloria S. Pryhuber, Thomas J. Mariani, Chen Li, Amy Mohan, Yawei Xu, Jinjiang Pang

Hypertension. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Hypertension. 2022 Jan; 79(1): 79–92. Published online 2021 Nov 5. doi: 10.1161/HYPERTENSIONAHA.120.16065

PMCID:: PMC8665100

Abstract Article PDF–1.4M

Select item 83441934.

Correlation of serum delta-like ligand-4 level with the severity of diabetic retinopathy

Yan Zhu, Jingcheng Hu, Xuan Du, Qionglei Fang, Yingyi Zhou, Ke Chen

BMC Endocr Disord. 2021; 21: 157. Published online 2021 Aug 6. doi: 10.1186/s12902-021-00814-6

PMCID:: PMC8344193

Abstract Article PDF–642K

Select item 82762205.

Adipose mesenchymal stem cells combined with platelet-rich plasma accelerate diabetic wound healing by modulating the Notch pathway

Nesrine Ebrahim, Arigue A. Dessouky, Ola Mostafa, Amira Hassouna, Mohamed M. Yousef, Yasmin Seleem, Eman Abd El Aziz M. El Gebaly, Mona M. Allam, Ayman Samir Farid, Bayan A. Saffaf, Dina Sabry, Ahmed Nawar, Ahmed A. Shoulah, Ahmed H. Khalil, Sami F. Abdalla, Mohamed El-Sherbiny, Nehal M. Elsherbiny, Rabab F. Salim

Stem Cell Res Ther. 2021; 12: 392. Published online 2021 Jul 13. doi: 10.1186/s13287-021-02454-y

PMCID:: PMC8276220

Abstract Article PDF–15M

Select item 82154256.

Murine Model of Cardiac Defects Observed in Adams-Oliver Syndrome Driven by Delta-Like Ligand-4 Haploinsufficiency

Prashan De Zoysa, Omar Toubat, Drayton Harvey, Jongkyu Choi, S. Ram Kumar

Stem Cells Dev. June 15, 2021; 30(12): 611–621. Published online 2021 Jun 8. doi: 10.1089/scd.2021.0058

PMCID:: PMC8215425

Abstract Article PDF–3.4M

Select item 73590837.

Protective effect of Soluble Epoxide Hydrolase Inhibition in Retinal Vasculopathy associated with Polycystic Kidney Disease

Jihong Lin, Jiong Hu, Andrea Schlotterer, Jing Wang, Matthias Kolibabka, Khader Awwad, Nadine Dietrich, Kristin Breitschopf, Paulus Wohlfart, Aimo Kannt, Katrin Lorenz, Yuxi Feng, Rüdiger Popp, Sigrid Hoffmann, Ingrid Fleming, Hans Peter Hammes

Theranostics. 2020; 10(17): 7857–7871. Published online 2020 Jun 22. doi: 10.7150/thno.43154

PMCID:: PMC7359083

Abstract Article PDF–2.3M

Select item 70250658.

Xuan Bi Tong Yu Fang Promotes Angiogenesis via VEGF-Notch1/Dll4 Pathway in Myocardial Ischemic Rats

Shuangdi Li, Jingrong Dong, Guang Ta, Yinghui Liu, Junfeng Cui, Xiaohui Li, Jing Song, Aidong Liu, Guangyu Cheng

Evid Based Complement Alternat Med. 2020; 2020: 5041629. Published online 2020 Feb 5. doi: 10.1155/2020/5041629

PMCID:: PMC7025065

Abstract Article PDF–6.1M

Select item 64527119.

Triggering of a Dll4–Notch1 loop impairs wound healing in diabetes

Xiaowei Zheng, Sampath Narayanan, Vivekananda Gupta Sunkari, Sofie Eliasson, Ileana Ruxandra Botusan, Jacob Grünler, Anca Irinel Catrina, Freddy Radtke, Cheng Xu, Allan Zhao, Neda Rajamand Ekberg, Urban Lendahl, Sergiu-Bogdan Catrina

Proc Natl Acad Sci U S A. 2019 Apr 2; 116(14): 6985–6994. Published online 2019 Mar 18. doi: 10.1073/pnas.1900351116

PMCID:: PMC6452711

Abstract Article PDF–2.3M

Select item 641087110.

NOTCH1 signaling induces pathological vascular permeability in diabetic retinopathy

Khalil Miloudi, Malika Oubaha, Catherine Ménard, Agnieszka Dejda, Vera Guber, Gael Cagnone, Ariel M. Wilson, Nicolas Tétreault, Gaëlle Mawambo, Francois Binet, Rony Chidiac, Chantal Delisle, Manuel Buscarlet, Agustin Cerani, Sergio Crespo-Garcia, Katie Bentley, Flavio Rezende, Jean-Sebastien Joyal, Frédérick A. Mallette, Jean-Philippe Gratton, Bruno Larrivée, Przemyslaw Sapieha

Proc Natl Acad Sci U S A. 2019 Mar 5; 116(10): 4538–4547. Published online 2019 Feb 20. doi: 10.1073/pnas.1814711116

PMCID:: PMC6410871

Abstract Article PDF–3.2M

Select item 634511111.

Gamma-Secretase Inhibitor, DAPT, Prevents the Development of Retinopathy of Prematurity in a Rat Model by Regulating the Delta-Like Ligand 4/Notch Homolog-1 (DLL4/Notch-1) Pathway

Wei Sun, Jing Li, Yinan Li, Jiao Zheng, Xiaoming Zhang, Xuelin Huang, Shujun Li

Med Sci Monit. 2019; 25: 492–499. Published online 2019 Jan 17. doi: 10.12659/MSM.913828

PMCID:: PMC6345111

Abstract Article PDF–2.0M

Select item 632944912.

A regulatory network involving Foxn4, Mash1 and delta-like 4/Notch1 generates V2a and V2b spinal interneurons from a common progenitor pool

Marta G. Del Barrio, Raquel Taveira-Marques, Yuko Muroyama, Dong-In Yuk, Shengguo Li, Mary Wines-Samuelson, Jie Shen, Hazel K. Smith, Mengqing Xiang, David Rowitch, William D. Richardson

Development. Author manuscript; available in PMC 2019 Jan 11.

Published in final edited form as: Development. 2007 Oct; 134(19): 3427–3436. Published online 2007 Aug 29. doi: 10.1242/dev.005868

PMCID:: PMC6329449

Abstract Article PDF–4.1M

Select item 614365713.

Total Flavonoids in Caragana (TFC) Promotes Angiogenesis and Enhances Cerebral Perfusion in a Rat Model of Ischemic Stroke

Qiansong He, Shirong Li, Lailai Li, Feiran Hu, Ning Weng, Xiaodi Fan, Shixiang Kuang

Front Neurosci. 2018; 12: 635. Published online 2018 Sep 12. doi: 10.3389/fnins.2018.00635

PMCID:: PMC6143657

Abstract Article PDF–3.8M

Select item 593803714.

Inhibition of Dll4/Notch1 pathway promotes angiogenesis of Masquelet’s induced membrane in rats

Qian Tang, Haimin Jin, Minji Tong, Gang Zheng, Zhongjie Xie, Shangkun Tang, Jialei Jin, Ping Shang, Huazi Xu, Liyan Shen, Yu Zhang, Haixiao Liu

Exp Mol Med. 2018 Apr; 50(4): 41. Published online 2018 Apr 20. doi: 10.1038/s12276-018-0062-9

PMCID:: PMC5938037

Abstract Article PDF–3.9M

Select item 583725215.

Notch-Tnf signalling is required for development and homeostasis of arterial valves

Yidong Wang, Bingruo Wu, Emily Farrar, Wendy Lui, Pengfei Lu, Donghong Zhang, Christina M. Alfieri, Kai Mao, Ming Chu, Di Yang, Di Xu, Michael Rauchman, Verdon Taylor, Simon J. Conway, Katherine E. Yutzey, Jonathan T. Butcher, Bin Zhou

Eur Heart J. 2017 Mar 1; 38(9): 675–686. Published online 2015 Oct 21. doi: 10.1093/eurheartj/ehv520

PMCID:: PMC5837252

Abstract Article PDF–2.2M

Select item 541872716.

Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients: a pilot study

Giorgio Aquila, Cinzia Fortini, Antonio Pannuti, Serena Delbue, Micaela Pannella, Marco Bruno Morelli, Cristiana Caliceti, Fausto Castriota, Monica de Mattei, Alessia Ongaro, Agnese Pellati, Pasquale Ferrante, Lucio Miele, Luigi Tavazzi, Roberto Ferrari, Paola Rizzo, Alberto Cremonesi

J Transl Med. 2017; 15: 98. Published online 2017 May 4. doi: 10.1186/s12967-017-1199-3

PMCID:: PMC5418727

Abstract Article PDF–2.6M

Select item 539229117.

VEGF promotes cartilage angiogenesis by phospho-ERK1/2 activation of Dll4 signaling in temporomandibular joint osteoarthritis caused by chronic sleep disturbance in Wistar rats

Yabing Dong, Gaoyi Wu, Ting Zhu, Hongyu Chen, Yong Zhu, Guoxiong Zhu, Fabin Han, Huaqiang Zhao

Oncotarget. 2017 Mar 14; 8(11): 17849–17861. Published online 2017 Jan 28. doi: 10.18632/oncotarget.14874

PMCID:: PMC5392291

Abstract Article PDF–4.1M

Select item 458732718.

Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth

Joseph Mertz, Haiyan Tan, Vishwajeeth Pagala, Bing Bai, Ping-Chung Chen, Yuxin Li, Ji-Hoon Cho, Timothy Shaw, Xusheng Wang, Junmin Peng

Mol Cell Proteomics. 2015 Jul; 14(7): 1898–1910. Published online 2015 Apr 30. doi: 10.1074/mcp.M114.045898

PMCID:: PMC4587327

Abstract Article PDF–2.6M

Select item 457463319.

Role of the DLL4-NOTCH System in PGF2alpha-Induced Luteolysis in the Pregnant Rat

Fatima Hernandez, Marina C. Peluffo, Richard L. Stouffer, Griselda Irusta, Marta Tesone

Biol Reprod. 2011 May; 84(5): 859–865. Published online 2011 Jan 5. doi: 10.1095/biolreprod.110.088708

PMCID:: PMC4574633

Abstract Article PDF–3.3M

Select item 448257320.

Context-Dependent Functional Divergence of the Notch Ligands DLL1 and DLL4 In Vivo

Kristina Preuße, Lena Tveriakhina, Karin Schuster-Gossler, Cláudia Gaspar, Alexandra Isabel Rosa, Domingos Henrique, Achim Gossler, Michael Stauber

PLoS Genet. 2015 Jun; 11(6): e1005328. Published online 2015 Jun 26. doi: 10.1371/journal.pgen.1005328

PMCID:: PMC4482573

Abstract Article PDF–16M

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