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Items: 1 to 20 of 52

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
IFN-γ stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii
Sambamurthy Chandrasekaran, Joshua A. Kochanowsky, Emily F. Merritt, Joseph S. Lagas, Ayesha Swannigan, Anita A. Koshy
Nat Commun. 2022; 13: 4605. Published online 2022 Aug 8. doi: 10.1038/s41467-022-32225-z
PMCID:
PMC9360015
AbstractArticlePDF–4.2M
3.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
4.
The IFN-inducible GTPase IRGB10 regulates viral replication and inflammasome activation during influenza A virus infection in mice
Shelbi Christgen, David Place, Min Zheng, Benoit Briard, Masahiro Yamamoto, Thirumala-Devi Kanneganti
Eur J Immunol. Author manuscript; available in PMC 2023 Feb 1.
Published in final edited form as: Eur J Immunol. 2022 Feb; 52(2): 285–296. Published online 2021 Nov 9. doi: 10.1002/eji.202149305
PMCID:
PMC8813912
AbstractArticlePDF–1.5M
5.
Genome Instability Independent of Type I Interferon Signaling Drives Neuropathology Caused by Impaired Ribonucleotide Excision Repair
Aditi, Susanna M. Downing, Patrick A. Schreiner, Young Don Kwak, Yang Li, Timothy I. Shaw, Helen R. Russell, Peter J. McKinnon
Neuron. Author manuscript; available in PMC 2022 Dec 15.
Published in final edited form as: Neuron. 2021 Dec 15; 109(24): 3962–3979.e6. Published online 2021 Oct 15. doi: 10.1016/j.neuron.2021.09.040
PMCID:
PMC8686690
AbstractArticlePDF–4.1M
6.
Murine Irgm Paralogs Regulate Nonredundant Functions To Execute Host Defense to Toxoplasma gondii
Jacob Dockterman, Brian E. Fee, Gregory A. Taylor, Jörn Coers
Infect Immun. 2021 Nov; 89(11): e00202-21. Prepublished online 2021 Aug 2. Published online 2021 Oct 15. doi: 10.1128/IAI.00202-21
PMCID:
PMC8519265
AbstractArticlePDF–2.2M
7.
Cell-autonomous Toxoplasma killing program requires Irgm2 but not its microbe vacuolar localization
Ariel Pradipta, Miwa Sasai, Kou Motani, Ji Su Ma, Youngae Lee, Hidetaka Kosako, Masahiro Yamamoto
Life Sci Alliance. 2021 Jul; 4(7): e202000960. Published online 2021 Jun 2. doi: 10.26508/lsa.202000960
PMCID:
PMC8200298
AbstractArticlePDF–2.9M
8.
Dynamin‐related Irgm proteins modulate LPS‐induced caspase‐11 activation and septic shock
Ryan Finethy, Jacob Dockterman, Miriam Kutsch, Nichole Orench‐Rivera, Graham D Wallace, Anthony S Piro, Sarah Luoma, Arun K Haldar, Seungmin Hwang, Jennifer Martinez, Meta J Kuehn, Gregory A Taylor, Jörn Coers
EMBO Rep. 2020 Nov 5; 21(11): e50830. Published online 2020 Oct 30. doi: 10.15252/embr.202050830
PMCID:
PMC7645254
AbstractArticlePDF–1.1M
9.
Irgm2 and Gate‐16 cooperatively dampen Gram‐negative bacteria‐induced caspase‐11 response
Elif Eren, Rémi Planès, Salimata Bagayoko, Pierre‐Jean Bordignon, Karima Chaoui, Audrey Hessel, Karin Santoni, Miriam Pinilla, Brice Lagrange, Odile Burlet‐Schiltz, Jonathan C Howard, Thomas Henry, Masahiro Yamamoto, Etienne Meunier
EMBO Rep. 2020 Nov 5; 21(11): e50829. Published online 2020 Oct 30. doi: 10.15252/embr.202050829
PMCID:
PMC7645206
AbstractArticlePDF–1.8M
10.
The ROP16III-dependent early immune response determines the subacute CNS immune response and type III Toxoplasma gondii survival
Shraddha Tuladhar, Joshua A. Kochanowsky, Apoorva Bhaskara, Yarah Ghotmi, Sambamurthy Chandrasekaran, Anita A. Koshy
PLoS Pathog. 2019 Oct; 15(10): e1007856. Published online 2019 Oct 24. doi: 10.1371/journal.ppat.1007856
PMCID:
PMC6812932
AbstractArticlePDF–4.6M
11.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
12.
Galectin-3 directs antimicrobial guanylate binding proteins to vacuoles furnished with bacterial secretion systems
Eric M. Feeley, Danielle M. Pilla-Moffett, Erin E. Zwack, Anthony S. Piro, Ryan Finethy, Joseph P. Kolb, Jennifer Martinez, Igor E. Brodsky, Jörn Coers
Proc Natl Acad Sci U S A. 2017 Feb 28; 114(9): E1698–E1706. Published online 2017 Feb 13. doi: 10.1073/pnas.1615771114
PMCID:
PMC5338555
AbstractArticlePDF–1.2M
13.
The macrophage IRF8/IRF1 regulome is required for protection against infections and is associated with chronic inflammation
David Langlais, Luis B. Barreiro, Philippe Gros
J Exp Med. 2016 Apr 4; 213(4): 585–603. doi: 10.1084/jem.20151764
PMCID:
PMC4821649
AbstractArticlePDF–3.1M
14.
IRGM3 Contributes to Immunopathology and Is Required for Differentiation of Antigen-Specific Effector CD8+ T Cells in Experimental Cerebral Malaria
Jintao Guo, James A. McQuillan, Belinda Yau, Gregory S. Tullo, Carole A. Long, Patrick Bertolino, Ben Roediger, Wolfgang Weninger, Gregory A. Taylor, Nicholas H. Hunt, Helen J. Ball, Andrew J. Mitchell
Infect Immun. 2015 Apr; 83(4): 1406–1417. Prepublished online 2015 Feb 2. Published online 2015 Mar 17. doi: 10.1128/IAI.02701-14
PMCID:
PMC4363434
AbstractArticlePDF–464K
15.
Identification of the Microsporidian Encephalitozoon cuniculi as a New Target of the IFNγ-Inducible IRG Resistance System
Marialice da Fonseca Ferreira-da-Silva, Helen Maria Springer-Frauenhoff, Wolfgang Bohne, Jonathan C. Howard
PLoS Pathog. 2014 Oct; 10(10): e1004449. Published online 2014 Oct 30. doi: 10.1371/journal.ppat.1004449
Correction in:
PLoS Pathog. 2014 Dec; 10(12): e1004590.
PMCID:
PMC4214799
AbstractArticlePDF–2.0M
16.
IFN-inducible p47 GTPases display differential responses to Schistosoma japonicum acute infection
Xuesong Chen, Xiaotang Du, Meijuan Zhang, Donghui Zhang, Minjun Ji, Guanling Wu
Cell Mol Immunol. 2010 Jan; 7(1): 69–76. Published online 2009 Dec 23. doi: 10.1038/cmi.2009.100
PMCID:
PMC4003251
AbstractArticlePDF–986K
17.
Guanylate binding proteins promote caspase-11–dependent pyroptosis in response to cytoplasmic LPS
Danielle M. Pilla, Jon A. Hagar, Arun K. Haldar, Ashley K. Mason, Daniel Degrandi, Klaus Pfeffer, Robert K. Ernst, Masahiro Yamamoto, Edward A. Miao, Jörn Coers
Proc Natl Acad Sci U S A. 2014 Apr 22; 111(16): 6046–6051. Published online 2014 Apr 8. doi: 10.1073/pnas.1321700111
PMCID:
PMC4000848
AbstractArticlePDF–859K
18.
The Immunity-related GTPase Irgm3 Relieves Endoplasmic Reticulum Stress Response during Coxsackievirus B3 Infection via a PI3K/Akt Dependent Pathway
Zhen Liu, Huifang M. Zhang, Ji Yuan, Xin Ye, Gregory A. Taylor, Decheng Yang
Cell Microbiol. Author manuscript; available in PMC 2013 Jun 24.
Published in final edited form as: Cell Microbiol. 2012 Jan; 14(1): 133–146. Published online 2011 Nov 10. doi: 10.1111/j.1462-5822.2011.01708.x
PMCID:
PMC3691006
AbstractArticlePDF–4.1M
19.
CD4+ T cells are necessary and sufficient to confer protection against C. trachomatis infection in the murine upper genital tract
David C. Gondek, Andrew J. Olive, Georg Stary, Michael N. Starnbach
J Immunol. Author manuscript; available in PMC 2013 Sep 1.
Published in final edited form as: J Immunol. 2012 Sep 1; 189(5): 2441–2449. Published online 2012 Aug 1. doi: 10.4049/jimmunol.1103032
PMCID:
PMC3690950
AbstractArticlePDF–3.0M
20.
IRG and GBP Host Resistance Factors Target Aberrant, “Non-self” Vacuoles Characterized by the Missing of “Self” IRGM Proteins
Arun K. Haldar, Hector A. Saka, Anthony S. Piro, Joe Dan Dunn, Stanley C. Henry, Gregory A. Taylor, Eva M. Frickel, Raphael H. Valdivia, Jörn Coers
PLoS Pathog. 2013 Jun; 9(6): e1003414. Published online 2013 Jun 13. doi: 10.1371/journal.ppat.1003414
PMCID:
PMC3681737
AbstractArticlePDF–5.1M

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