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Select item 109594151.

FOXL2 interaction with different binding partners regulates the dynamics of ovarian development

Roberta Migale, Michelle Neumann, Richard Mitter, Mahmoud-Reza Rafiee, Sophie Wood, Jessica Olsen, Robin Lovell-Badge

Sci Adv. 2024 Mar 22; 10(12): eadl0788. Published online 2024 Mar 22. doi: 10.1126/sciadv.adl0788

PMCID:: PMC10959415

Abstract Article PDF–4.4M

Select item 108943032.

DNA polymerase iota promotes EMT and metastasis of esophageal squamous cell carcinoma by interacting with USP7 to stabilize HIF-1α

Aidi Gao, Mingxia Zhang, Shuang qi Zhu, Shitao Zou, Hengrui Chen, Xiaoqin Li, Chao He, Liangsu Zhou, Yan Mei, Weiqun Ding, Jundong Zhou, Yue Zhou, Yuandong Cao

Cell Death Dis. 2024 Feb; 15(2): 171. Published online 2024 Feb 24. doi: 10.1038/s41419-024-06552-6

PMCID:: PMC10894303

Abstract Article PDF–3.7M

Select item 101914413.

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities

Chao Liu, Lingang Sun, Yijun Tan, Qi Wang, Tao Luo, Chenlu Li, Nan Yao, Yuting Xie, Xiao Yi, Yi Zhu, Tiannan Guo, Junfeng Ji

Sci Adv. 2023 May; 9(20): eade3888. Published online 2023 May 17. doi: 10.1126/sciadv.ade3888

PMCID:: PMC10191441

Abstract Article PDF–2.4M

Select item 101476044.

USP7 controls NGN3 stability and pancreatic endocrine lineage development

Teodora Manea, Jessica Kristine Nelson, Cristina Maria Garrone, Karin Hansson, Ian Evans, Axel Behrens, Rocio Sancho

Nat Commun. 2023; 14: 2457. Published online 2023 Apr 28. doi: 10.1038/s41467-023-38146-9

PMCID:: PMC10147604

Abstract Article PDF–9.0M

Select item 101049585.

Organ defects of the Usp7^K444R mutant mouse strain indicate the essential role of K63-polyubiquitinated Usp7 in organ formation

Han-Tsang Wu, Yueh-Te Lin, Shan Hwu Chew, Kou-Juey Wu

Biomed J. 2023 Feb; 46(1): 122–133. Published online 2022 Feb 18. doi: 10.1016/j.bj.2022.02.002

PMCID:: PMC10104958

Abstract Article PDF–3.6M

Select item 99689856.

USP7 inactivation suppresses APC-mutant intestinal hyperproliferation and tumor development

Laura Novellasdemunt, Anna Kucharska, Anna Baulies, Colin Hutton, Georgios Vlachogiannis, Dimitra Repana, Andrew Rowan, A. Suárez-Bonnet, Francesca Ciccarelli, Nicola Valeri, Vivian S.W. Li

Stem Cell Reports. 2023 Feb 14; 18(2): 570–584. Published online 2023 Jan 19. doi: 10.1016/j.stemcr.2022.12.013

PMCID:: PMC9968985

Abstract Article PDF–5.8M

Select item 97339377.

Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia

Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, Igor Fijalkwoski, Cristina Borin, Jolien Van Laere, Monique Payton, Byoung-Kyu Cho, Cuijuan Han, Limin Sun, Valentina Serafin, George Yacu, Wouter Von Loocke, Giuseppe Basso, Giulia Veltri, Ingrid Dreveny, Issam Ben-Sahra, Young Ah Goo, Stephanie L. Safgren, Yi-Chien Tsai, Beat Bornhauser, Praveen Kumar Suraneni, Alexandre Gaspar-Maia, Irawati Kandela, Pieter Van Vlierberghe, John D. Crispino, Aristotelis Tsirigos, Panagiotis Ntziachristos

Sci Adv. 2022 Dec; 8(49): eabq8437. Published online 2022 Dec 9. doi: 10.1126/sciadv.abq8437

PMCID:: PMC9733937

Abstract Article PDF–2.2M

Select item 94423008.

Functional skewing of TRIM21‐SIRT5 interplay dictates IL‐1β production in DSS‐induced colitis

Pengbo Yao, Taiqi Chen, Peng Jiang, Li Li, Wenjing Du

EMBO Rep. 2022 Sep; 23(9): e54391. Published online 2022 Jun 30. doi: 10.15252/embr.202154391

PMCID:: PMC9442300

Abstract Article PDF–5.2M

Select item 94128189.

USP7 Promotes deubiquitination and stabilization of MyD88 to enhance immune responses

Na Zhang, Fei Wang, Gaomeng Zhang, Qi Zhang, Yuhong Liu, Qiao Wang, Mohamed Shafey Elsharkawy, Maiqing Zheng, Jie Wen, Guiping Zhao, Qinghe Li

Front Immunol. 2022; 13: 900243. Published online 2022 Aug 12. doi: 10.3389/fimmu.2022.900243

PMCID:: PMC9412818

Abstract Article PDF–2.0M

Select item 925349610.

Role of the DUB enzyme USP7 in dendritic arborization, neuronal migration, and autistic-like behaviors in mice

Hui Qiao, Yuan Tian, Yuda Huo, Heng-Ye Man

iScience. 2022 Jul 15; 25(7): 104595. Published online 2022 Jun 14. doi: 10.1016/j.isci.2022.104595

PMCID:: PMC9253496

Abstract Article PDF–5.8M

Select item 906265911.

Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0

Fujun Hou, Zeyu Sun, Yue Deng, Siyu Chen, Xiyuan Yang, Feiyang Ji, Menghao Zhou, Keyi Ren, Dongli Pan

Front Microbiol. 2022; 13: 856471. Published online 2022 Apr 18. doi: 10.3389/fmicb.2022.856471

PMCID:: PMC9062659

Abstract Article PDF–3.5M

Select item 900769212.

USP7 Attenuates Endoplasmic Reticulum Stress and NF-κB Signaling to Modulate Chondrocyte Proliferation, Apoptosis, and Inflammatory Response under Inflammation

Xiaofei Dong, Chang Yang, Yao Luo, Wei Dong, Xiaoxiao Xu, Yanru Wu, Jiawei Wang

Oxid Med Cell Longev. 2022; 2022: 1835900. Published online 2022 Apr 6. doi: 10.1155/2022/1835900

PMCID:: PMC9007692

Abstract Article PDF–5.8M

Select item 793877013.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 788293314.

The miRNA‐15b/USP7/KDM6B axis engages in the initiation of osteoporosis by modulating osteoblast differentiation and autophagy

Xiaohui Lu, Yuantao Zhang, Yin Zheng, Bin Chen

J Cell Mol Med. 2021 Feb; 25(4): 2069–2081. Published online 2021 Jan 12. doi: 10.1111/jcmm.16139

PMCID:: PMC7882933

Abstract Article PDF–991K

Select item 777340415.

Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy

Anna Pluciennik, Yuhong Liu, Elana Molotsky, Gregory B. Marsh, Bedri Ranxhi, Frederick J. Arnold, Sophie St.-Cyr, Beverly Davidson, Naemeh Pourshafie, Andrew P. Lieberman, Wei Gu, Sokol V. Todi, Diane E. Merry

J Clin Invest. 2021 Jan 4; 131(1): e134565. Published online 2021 Jan 4. doi: 10.1172/JCI134565

PMCID:: PMC7773404

Abstract Article PDF–15M

Select item 754801016.

USP7 mediates pathological hepatic de novo lipogenesis through promoting stabilization and transcription of ZNF638

Wenkai Ni, Shengli Lin, Saiyan Bian, Wenjie Zheng, Lishuai Qu, Yihui Fan, Cuihua Lu, Mingbing Xiao, Pinghong Zhou

Cell Death Dis. 2020 Oct; 11(10): 843. Published online 2020 Oct 10. doi: 10.1038/s41419-020-03075-8

PMCID:: PMC7548010

Abstract Article PDF–4.1M

Select item 745012217.

The deubiquitinase USP7 uses a distinct ubiquitin-like domain to deubiquitinate NF-ĸB subunits

Izaskun Mitxitorena, Domenico Somma, Jennifer P. Mitchell, Matti Lepistö, Christian Tyrchan, Emma L. Smith, Patrick A. Kiely, Helen Walden, Karen Keeshan, Ruaidhrí J. Carmody

J Biol Chem. 2020 Aug 14; 295(33): 11754–11763. Published online 2020 Jun 25. doi: 10.1074/jbc.RA120.014113

PMCID:: PMC7450122

Abstract Article PDF–2.5M

Select item 741599118.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 721026619.

A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation

Jung-Min Kim, Yeon-Suk Yang, Kwang Hwan Park, Xianpeng Ge, Ren Xu, Na Li, Minkyung Song, Hyunho Chun, Seoyeon Bok, Julia F. Charles, Odile Filhol-Cochet, Brigitte Boldyreff, Teresa Dinter, Paul B. Yu, Ning Kon, Wei Gu, Takeshi Takarada, Matthew B. Greenblatt, Jae-Hyuck Shim

Nat Commun. 2020; 11: 2289. Published online 2020 May 8. doi: 10.1038/s41467-020-16038-6

PMCID:: PMC7210266

Abstract Article PDF–5.7M

Select item 705917220.

Inhibition of USP7 activity selectively eliminates senescent cells in part via restoration of p53 activity

Yonghan He, Wen Li, Dongwen Lv, Xin Zhang, Xuan Zhang, Yuma T. Ortiz, Vivekananda Budamagunta, Judith Campisi, Guangrong Zheng, Daohong Zhou

Aging Cell. 2020 Mar; 19(3): e13117. Published online 2020 Feb 16. doi: 10.1111/acel.13117

PMCID:: PMC7059172

Abstract Article PDF–1.0M

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