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Items: 1 to 20 of 22

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Intestinal GPR119 activation by microbiota-derived metabolites impacts feeding behavior and energy metabolism
Miki Igarashi, Tetsuhiko Hayakawa, Haruka Tanabe, Keita Watanabe, Akari Nishida, Ikuo Kimura
Mol Metab. 2023 Jan; 67: 101649. Published online 2022 Nov 30. doi: 10.1016/j.molmet.2022.101649
PMCID:
PMC9771719
AbstractArticlePDF–3.0M
3.
GPR119 - a major Enteroendocrine Sensor of Dietary Triglyceride Metabolites Co-acting in Synergy with FFA1 (GPR40)
Jeppe P. Ekberg, Maria Hauge, Line V. Kristensen, Andreas N. Madsen, Maja S. Engelstoft, Anna-Sofie Husted, Rasmus Sichlau, Kristoffer Egerod, Timothy Kowalski, Fiona M. Gribble, Frank Reimann, Harald S. Hansen, Andrew D. Howard, Birgitte Holst, Thue W. Schwartz
Endocrinology. Author manuscript; available in PMC 2020 May 11.
Published in final edited form as: Endocrinology. 2016 Dec 1; 157(12): 4561–4569. Published online 2016 Oct 25. doi: 10.1210/en.2016-1334
PMCID:
PMC7212052
AbstractArticlePDF–1.1M
4.
N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis
Trisha J. Grevengoed, Samuel A. J. Trammell, Michele K. McKinney, Natalia Petersen, Rebecca L. Cardone, Jens S. Svenningsen, Daisuke Ogasawara, Christina C. Nexøe-Larsen, Filip K. Knop, Thue W. Schwartz, Richard G. Kibbey, Benjamin F. Cravatt, Matthew P. Gillum
Proc Natl Acad Sci U S A. 2019 Dec 3; 116(49): 24770–24778. Published online 2019 Nov 18. doi: 10.1073/pnas.1916288116
PMCID:
PMC6900532
AbstractArticlePDF–1.7M
5.
GPR119 Agonism Increases Glucagon Secretion During Insulin-Induced Hypoglycemia
Nina Xiaoyan Li, Stacey Brown, Tim Kowalski, Margaret Wu, Liming Yang, Ge Dai, Aleksandr Petrov, Yuyan Ding, Tamara Dlugos, Harold B. Wood, Liangsu Wang, Mark Erion, Robert Sherwin, David E. Kelley
Diabetes. 2018 Jul; 67(7): 1401–1413. Published online 2018 Apr 18. doi: 10.2337/db18-0031
PMCID:
PMC6014553
AbstractArticlePDF–2.4M
6.
β-Cell Inactivation of Gpr119 Unmasks Incretin Dependence of GPR119-Mediated Glucoregulation
Brandon L. Panaro, Grace B. Flock, Jonathan E. Campbell, Jacqueline L. Beaudry, Xiemin Cao, Daniel J. Drucker
Diabetes. 2017 Jun; 66(6): 1626–1635. Published online 2017 Mar 2. doi: 10.2337/db17-0017
PMCID:
PMC5860191
AbstractArticlePDF–1.7M
7.
A GPR119 Signaling System in the Murine Eye Regulates Intraocular Pressure in a Sex-Dependent Manner
Sally Miller, Sherry Shu-Jung Hu, Emma Leishman, Dan Morgan, Jim Wager-Miller, Ken Mackie, Heather B. Bradshaw, Alex Straiker
Invest Ophthalmol Vis Sci. 2017 Jul; 58(7): 2930–2938. doi: 10.1167/iovs.16-21330
PMCID:
PMC5469424
AbstractArticlePDF–1.0M
8.
N-Oleoyldopamine Enhances Glucose Homeostasis through the Activation of GPR119
Zhi-Liang Chu, Chris Carroll, Ruoping Chen, Jean Alfonso, Veronica Gutierrez, Hongmei He, Annette Lucman, Charles Xing, Kristen Sebring, Jinyao Zhou, Brandee Wagner, David Unett, Robert M. Jones, Dominic P. Behan, James Leonard
Mol Endocrinol. January 1, 2010; 24(1): 161–170. doi: 10.1210/me.2009-0239
PMCID:
PMC5428146
AbstractArticle
9.
Evidence for a GPR18 Role in Diurnal Regulation of Intraocular Pressure
Sally Miller, Emma Leishman, Olivia Oehler, Laura Daily, Natalia Murataeva, Jim Wager-Miller, Heather Bradshaw, Alex Straiker
Invest Ophthalmol Vis Sci. 2016 Nov; 57(14): 6419–6426. doi: 10.1167/iovs.16-19437
PMCID:
PMC5132083
AbstractArticlePDF–929K
10.
Angelica dahurica Extracts Improve Glucose Tolerance through the Activation of GPR119
Eun-Young Park, Eung-Hwi Kim, Chul-Young Kim, Mi-Hwi Kim, Jin-Seung Choung, Yoon-Sin Oh, Hong-Sub Moon, Hee-Sook Jun
PLoS One. 2016; 11(7): e0158796. Published online 2016 Jul 8. doi: 10.1371/journal.pone.0158796
PMCID:
PMC4938581
AbstractArticlePDF–2.7M
11.
Discovery and characterization of novel smallmolecule agonists of G protein-coupled receptor 119
Shu-yong Zhang, Jing Li, Xin Xie
Acta Pharmacol Sin. 2014 Apr; 35(4): 540–548. Published online 2014 Mar 31. doi: 10.1038/aps.2014.8
PMCID:
PMC4813729
AbstractArticlePDF–1.7M
12.
Lipid derivatives activate GPR119 and trigger GLP-1 secretion in primary murine L-cells
Daryl Hodge, Leslie L. Glass, Eleftheria Diakogiannaki, Ramona Pais, Carol Lenaghan, David M. Smith, Marianne Wedin, Mohammad Bohlooly-Y, Fiona M. Gribble, Frank Reimann
Peptides. 2016 Mar; 77: 16–20. doi: 10.1016/j.peptides.2015.06.012
PMCID:
PMC4788502
AbstractArticlePDF–458K
13.
Molecular matchmaking between the popular weight-loss herb Hoodia gordonii and GPR119, a potential drug target for metabolic disorder
Shuyong Zhang, Yuyong Ma, Jing Li, Junjun Ma, Biao Yu, Xin Xie
Proc Natl Acad Sci U S A. 2014 Oct 7; 111(40): 14571–14576. Published online 2014 Sep 22. doi: 10.1073/pnas.1324130111
PMCID:
PMC4210048
AbstractArticlePDF–1.0M
14.
A lincRNA-DYNLRB2-2/GPR119/GLP-1R/ABCA1-dependent signal transduction pathway is essential for the regulation of cholesterol homeostasis
Yan-Wei Hu, Jun-Yao Yang, Xin Ma, Zhi-Ping Chen, Ya-Rong Hu, Jia-Yi Zhao, Shu-Fen Li, Yu-Rong Qiu, Jing-Bo Lu, Yan-Chao Wang, Ji-Juan Gao, Yan-Hua Sha, Lei Zheng, Qian Wang
J Lipid Res. 2014 Apr; 55(4): 681–697. doi: 10.1194/jlr.M044669
PMCID:
PMC3966702
AbstractArticlePDF–2.9M
15.
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data
Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson
Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977
PMCID:
PMC3964955
AbstractArticlePDF–5.7M
16.
Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins
Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins
Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110
PMCID:
PMC3581954
AbstractArticlePDF–2.3M
17.
Stimulating β-Cell Regeneration by Combining a GPR119 Agonist with a DPP-IV Inhibitor
Ansarullah, Yan Lu, Martha Holstein, Brittany DeRuyter, Alex Rabinovitch, Zhiguang Guo
PLoS One. 2013; 8(1): e53345. Published online 2013 Jan 29. doi: 10.1371/journal.pone.0053345
PMCID:
PMC3558424
AbstractArticlePDF–6.2M
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
GPR119 Regulates Murine Glucose Homeostasis Through Incretin Receptor-Dependent and Independent Mechanisms
Grace Flock, Dianne Holland, Yutaka Seino, Daniel J. Drucker
Endocrinology. Author manuscript; available in PMC 2012 Feb 1.
Published in final edited form as: Endocrinology. 2011 Feb; 152(2): 374–383. Published online 2010 Nov 10. doi: 10.1210/en.2010-1047
PMCID:
PMC3082521
AbstractArticlePDF–1.1M
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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