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Items: 1 to 20 of 54

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Melanocortin-3 receptor expression in AgRP neurons is required for normal activation of the neurons in response to energy deficiency
Yijun Gui, Naima S. Dahir, Yanan Wu, Griffin Downing, Patrick Sweeney, Roger D. Cone
Cell Rep. Author manuscript; available in PMC 2023 Dec 19.
Published in final edited form as: Cell Rep. 2023 Oct 31; 42(10): 113188. Published online 2023 Oct 3. doi: 10.1016/j.celrep.2023.113188
PMCID:
PMC10728878
AbstractArticlePDF–3.5M
3.
Paraventricular Thalamic MC3R Circuits Link Energy Homeostasis with Anxiety-Related Behavior
Dajin Cho, Kyle O'Berry, Ingrid Camila Possa-Paranhos, Jared Butts, Naraen Palanikumar, Patrick Sweeney
J Neurosci. 2023 Sep 6; 43(36): 6280–6296. doi: 10.1523/JNEUROSCI.0704-23.2023
PMCID:
PMC10490510
AbstractArticlePDF–5.4M
4.
Organization of neural systems expressing melanocortin-3 receptors in the mouse brain: Evidence for sexual dimorphism
Michelle N. Bedenbaugh, Samantha C. Brener, Jose Maldonado, Rachel N. Lippert, Patrick Sweeney, Roger D. Cone, Richard B. Simerly
J Comp Neurol. Author manuscript; available in PMC 2023 Nov 1.
Published in final edited form as: J Comp Neurol. 2022 Nov; 530(16): 2835–2851. Published online 2022 Jun 30. doi: 10.1002/cne.25379
PMCID:
PMC9724692
AbstractArticlePDF–2.4M
5.
The melanocortin-3 receptor is a pharmacological target for the regulation of anorexia
Patrick Sweeney, Michelle N. Bedenbaugh, Jose Maldonado, Pauline Pan, Katelyn Fowler, Savannah Y. Williams, Luis E. Gimenez, Masoud Ghamari-Langroudi, Griffin Downing, Yijun Gui, Colleen K. Hadley, Stephen T. Joy, Anna K. Mapp, Richard B. Simerly, Roger D. Cone
Sci Transl Med. Author manuscript; available in PMC 2022 Apr 21.
Published in final edited form as: Sci Transl Med. 2021 Apr 21; 13(590): eabd6434. doi: 10.1126/scitranslmed.abd6434
PMCID:
PMC9022017
AbstractArticlePDF–3.0M
6.
MC3R links nutritional state to childhood growth and the timing of puberty
B. Y. H. Lam, A. Williamson, S. Finer, F. R. Day, J. A. Tadross, A. Gonçalves Soares, K. Wade, P. Sweeney, M. N. Bedenbaugh, D. T. Porter, A. Melvin, K. L. J. Ellacott, R. N. Lippert, S. Buller, J. Rosmaninho-Salgado, G. K. C. Dowsett, K. E. Ridley, Z. Xu, I. Cimino, D. Rimmington, K. Rainbow, K. Duckett, S. Holmqvist, A. Khan, X. Dai, E. G. Bochukova, Genes & Health Research Team, R. C. Trembath, H. C. Martin, A. P. Coll, D. H. Rowitch, N. J. Wareham, D. A. van Heel, N. Timpson, R. B. Simerly, K. K. Ong, R. D. Cone, C. Langenberg, J. R. B. Perry, G. S. Yeo, S. O’Rahilly
Nature. Author manuscript; available in PMC 2022 Nov 3.
Published in final edited form as: Nature. 2021 Nov; 599(7885): 436–441. Published online 2021 Nov 3. doi: 10.1038/s41586-021-04088-9
PMCID:
PMC8819628
AbstractArticlePDF–3.2M
7.
VTA MC3R neurons control feeding in an activity- and sex-dependent manner in mice
Anna I. Dunigan, David P. Olson, Aaron G. Roseberry
Neuropharmacology. Author manuscript; available in PMC 2022 Oct 1.
Published in final edited form as: Neuropharmacology. 2021 Oct 1; 197: 108746. Published online 2021 Aug 8. doi: 10.1016/j.neuropharm.2021.108746
PMCID:
PMC8478831
AbstractArticlePDF–2.1M
8.
Identification of novel GPCR partners of the central melanocortin signaling
Yunpeng Li, Xiaozhu Wang, Liumei Lu, Meng Wang, Yue Zhai, Xiaolu Tai, Diliqingna Dilimulati, Xiaowei Lei, Jing Xu, Cong Zhang, Yanbin Fu, Shen Qu, Qingfeng Li, Chao Zhang
Mol Metab. 2021 Nov; 53: 101317. Published online 2021 Aug 14. doi: 10.1016/j.molmet.2021.101317
PMCID:
PMC8458986
AbstractArticlePDF–4.0M
9.
Whole-brain efferent and afferent connectivity of mouse ventral tegmental area melanocortin-3 receptor neurons
Anna I. Dunigan, Andrew M. Swanson, David P Olson, Aaron G. Roseberry
J Comp Neurol. Author manuscript; available in PMC 2022 Apr 15.
Published in final edited form as: J Comp Neurol. 2021 Apr 15; 529(6): 1157–1183. Published online 2020 Sep 10. doi: 10.1002/cne.25013
PMCID:
PMC7867604
AbstractArticlePDF–4.6M
10.
Therapeutic senescence via GPCR activation in synovial fibroblasts facilitates resolution of arthritis
Trinidad Montero-Melendez, Ai Nagano, Claude Chelala, Andrew Filer, Christopher D. Buckley, Mauro Perretti
Nat Commun. 2020; 11: 745. Published online 2020 Feb 6. doi: 10.1038/s41467-020-14421-x
PMCID:
PMC7005314
AbstractArticlePDF–5.5M
11.
Lateral Hypothalamic Mc3R-Expressing Neurons Modulate Locomotor Activity, Energy Expenditure, and Adiposity in Male Mice
Hongjuan Pei, Christa M Patterson, Amy K Sutton, Korri H Burnett, Martin G Myers, Jr, David P Olson
Endocrinology. 2019 Feb; 160(2): 343–358. Published online 2018 Dec 11. doi: 10.1210/en.2018-00747
PMCID:
PMC6937456
AbstractArticle
12.
Regulation of energy rheostasis by the melanocortin-3 receptor
Masoud Ghamari-Langroudi, Isin Cakir, Rachel N. Lippert, Patrick Sweeney, Michael J. Litt, Kate L. J. Ellacott, Roger D. Cone
Sci Adv. 2018 Aug; 4(8): eaat0866. Published online 2018 Aug 22. doi: 10.1126/sciadv.aat0866
PMCID:
PMC6105298
AbstractArticlePDF–4.5M
13.
Melanocortin-3 receptors expressed in Nkx2.1(+ve) neurons are sufficient for controlling appetitive responses to hypocaloric conditioning
Clémence Girardet, Maria M. Mavrikaki, Joseph R. Stevens, Courtney A. Miller, Daniel L. Marks, Andrew A. Butler
Sci Rep. 2017; 7: 44444. Published online 2017 Mar 15. doi: 10.1038/srep44444
PMCID:
PMC5353610
AbstractArticlePDF–2.3M
14.
Melanocortin-3 receptors in the limbic system mediate feeding-related motivational responses during weight loss
Maria Mavrikaki, Clemence Girardet, Andras Kern, Alicia Faruzzi Brantley, Courtney A. Miller, Heather Macarthur, Daniel L. Marks, Andrew A. Butler
Mol Metab. 2016 Jul; 5(7): 566–579. Published online 2016 May 12. doi: 10.1016/j.molmet.2016.05.002
PMCID:
PMC4921936
AbstractArticlePDF–2.7M
15.
A mouse model for a partially inactive obesity-associated human MC3R variant
Bonggi Lee, Jashin Koo, Joo Yun Jun, Oksana Gavrilova, Yongjun Lee, Arnold Y. Seo, Dezmond C. Taylor-Douglas, Diane C. Adler-Wailes, Faye Chen, Ryan Gardner, Dimitri Koutzoumis, Roya Sherafat Kazemzadeh, Robin B. Roberson, Jack A. Yanovski
Nat Commun. 2016; 7: 10522. Published online 2016 Jan 28. doi: 10.1038/ncomms10522
PMCID:
PMC4738366
AbstractArticlePDF–1.5M
16.
Both MC1 and MC3 Receptors Provide Protection from Cerebral Ischemia Reperfusion Induced Neutrophil Recruitment
Paul M. Holloway, Pascal F. Durrenberger, Marjan Trutschl, Urska Cvek, Dianne Cooper, A. Wayne Orr, Mauro Perretti, Stephen J. Getting, Felicity N. E. Gavins
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2016 Sep 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Sep; 35(9): 1936–1944. Published online 2015 Jun 25. doi: 10.1161/ATVBAHA.115.305348
PMCID:
PMC4552587
AbstractArticlePDF–789K
17.
Spatially Heterogeneous Choroid Plexus Transcriptomes Encode Positional Identity and Contribute to Regional CSF Production
Melody P. Lun, Matthew B. Johnson, Kevin G. Broadbelt, Momoko Watanabe, Young-jin Kang, Kevin F. Chau, Mark W. Springel, Alexandra Malesz, André M.M. Sousa, Mihovil Pletikos, Tai Adelita, Monica L. Calicchio, Yong Zhang, Michael J. Holtzman, Hart G.W. Lidov, Nenad Sestan, Hanno Steen, Edwin S. Monuki, Maria K. Lehtinen
J Neurosci. 2015 Mar 25; 35(12): 4903–4916. doi: 10.1523/JNEUROSCI.3081-14.2015
Correction in:
J Neurosci. 2015 Jun 3; 35(22): 8686.
PMCID:
PMC4389594
AbstractArticlePDF–3.3M
18.
A high resolution spatiotemporal atlas of gene expression of the developing mouse brain
Carol L. Thompson, Lydia Ng, Vilas Menon, Salvador Martinez, Chang-Kyu Lee, Katie Glattfelder, Susan M. Sunkin, Alex Henry, Christopher Lau, Chinh Dang, Raquel Garcia-Lopez, Almudena Martinez-Ferre, Ana Pombero, John L.R. Rubenstein, Wayne B. Wakeman, John Hohmann, Nick Dee, Andrew J. Sodt, Rob Young, Kimberly Smith, Thuc-Nghi Nguyen, Jolene Kidney, Leonard Kuan, Andreas Jeromin, Ajamete Kaykas, Jeremy Miller, Damon Page, Geri Orta, Amy Bernard, Zackery Riley, Simon Smith, Paul Wohnoutka, Mike Hawrylycz, Luis Puelles, Allan R. Jones
Neuron. Author manuscript; available in PMC 2015 Jul 16.
Published in final edited form as: Neuron. 2014 Jul 16; 83(2): 309–323. Published online 2014 Jun 19. doi: 10.1016/j.neuron.2014.05.033
PMCID:
PMC4319559
AbstractArticlePDF–3.0M
19.
Evaluation of Hypothalamic Murineand Human Melanocortin 3 Receptor Transcript Structure
Dezmond C Taylor-Douglas, Arunabha Basu, Ryan M. Gardner, Sender Aspelund, Xin Wen, Jack A. Yanovski
Biochem Biophys Res Commun. Author manuscript; available in PMC 2015 Nov 7.
Published in final edited form as: Biochem Biophys Res Commun. 2014 Nov 7; 454(1): 234–238. Published online 2014 Oct 22. doi: 10.1016/j.bbrc.2014.10.072
PMCID:
PMC4312205
AbstractArticlePDF–1.2M
20.
Assessing Interactions Between Ghsr and Mc3r Reveals a Role for AgRP in the Expression of Food Anticipatory Activity in Male Mice
Clemence Girardet, Maria Mavrikaki, Mark R. Southern, Roy G. Smith, Andrew A. Butler
Endocrinology. 2014 Dec; 155(12): 4843–4855. Published online 2014 Sep 11. doi: 10.1210/en.2014-1497
PMCID:
PMC4239417
AbstractArticle

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