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Items: 1 to 20 of 61

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
3.
Deficiency of Wdr60 and Wdr34 cause distinct neural tube malformation phenotypes in early embryos
Lu Yan, Hailing Yin, Yiwei Mi, Yu Wu, Yufang Zheng
Front Cell Dev Biol. 2023; 11: 1084245. Published online 2023 May 9. doi: 10.3389/fcell.2023.1084245
PMCID:
PMC10203710
AbstractArticlePDF–4.6M
4.
Distinct overlapping functions for Prickle1 and Prickle2 in the polarization of the airway epithelium
Koshi Kunimoto, Alexis T. Weiner, Jeffrey D. Axelrod, Eszter K. Vladar
Front Cell Dev Biol. 2022; 10: 976182. Published online 2022 Sep 13. doi: 10.3389/fcell.2022.976182
PMCID:
PMC9513604
AbstractArticlePDF–3.4M
5.
Wnt5a–Vangl1/2 signaling regulates the position and direction of lung branching through the cytoskeleton and focal adhesions
Kuan Zhang, Erica Yao, Ethan Chuang, Biao Chen, Evelyn Y. Chuang, Regan F. Volk, Katherine L. Hofmann, Balyn Zaro, Pao-Tien Chuang
PLoS Biol. 2022 Aug; 20(8): e3001759. Published online 2022 Aug 26. doi: 10.1371/journal.pbio.3001759
PMCID:
PMC9469998
AbstractArticlePDF–4.3M
6.
A functional circuit formed by the autonomic nerves and myofibroblasts controls mammalian alveolar formation for gas exchange
Kuan Zhang, Erica Yao, Shao-An Wang, Ethan Chuang, Julia Wong, Liliana Minichiello, Andrew Schroeder, Walter Eckalbar, Paul J. Wolters, Pao-Tien Chuang
Dev Cell. Author manuscript; available in PMC 2023 Jul 11.
Published in final edited form as: Dev Cell. 2022 Jul 11; 57(13): 1566–1581.e7. Published online 2022 Jun 16. doi: 10.1016/j.devcel.2022.05.021
PMCID:
PMC9308505
AbstractArticlePDF–5.9M
7.
A peptide interfering with the dimerization of oncogenic KITENIN protein and its stability suppresses colorectal tumour progression
Sung Jin Kim, Eun Gene Sun, Jeong A Bae, Sehoon Park, Chang‐Soo Hong, Zee‐Yong Park, Hangun Kim, Kyung Keun Kim
Clin Transl Med. 2022 Jul; 12(7): e871. Published online 2022 Jul 19. doi: 10.1002/ctm2.871
PMCID:
PMC9296036
AbstractArticlePDF–5.9M
8.
Phosphatidylinositol transfer protein/planar cell polarity axis regulates neocortical morphogenesis by supporting interkinetic nuclear migration
Zhigang Xie, Vytas A. Bankaitis
Cell Rep. Author manuscript; available in PMC 2022 Jun 24.
Published in final edited form as: Cell Rep. 2022 May 31; 39(9): 110869. doi: 10.1016/j.celrep.2022.110869
PMCID:
PMC9230501
AbstractArticlePDF–3.9M
9.
Deletions in VANGL1 are a risk factor for antibody-mediated kidney disease
Simon H. Jiang, Sevcan Mercan, Ilenia Papa, Max Moldovan, Giles D. Walters, Mark Koina, Mitali Fadia, Maurice Stanley, Tom Lea-Henry, Amelia Cook, Julia Ellyard, Brendan McMorran, Madhivanan Sundaram, Russell Thomson, Pablo F. Canete, Wendy Hoy, Holly Hutton, Monika Srivastava, Kathryn McKeon, Iñigo de la Rúa Figueroa, Ricard Cervera, Raquel Faria, Sandra D’Alfonso, Mariele Gatto, Vicki Athanasopoulos, Matthew Field, John Mathews, Eun Cho, Thomas D. Andrews, A. Richard Kitching, Matthew C. Cook, Marta Alarcon Riquelme, Melanie Bahlo, Carola G. Vinuesa
Cell Rep Med. 2021 Dec 21; 2(12): 100475. Published online 2021 Dec 21. doi: 10.1016/j.xcrm.2021.100475
PMCID:
PMC8714939
AbstractArticlePDF–4.3M
10.
Planar cell polarity induces local microtubule bundling for coordinated ciliary beating
Shogo Nakayama, Tomoki Yano, Toshinori Namba, Satoshi Konishi, Maki Takagishi, Elisa Herawati, Tomoki Nishida, Yasuo Imoto, Shuji Ishihara, Masahide Takahashi, Ken’ya Furuta, Kazuhiro Oiwa, Atsushi Tamura, Sachiko Tsukita
J Cell Biol. 2021 Jul 5; 220(7): e202010034. Published online 2021 Apr 30. doi: 10.1083/jcb.202010034
PMCID:
PMC8094116
AbstractArticlePDF–9.9M
11.
A Wnt5 Activity Asymmetry and Intercellular Signaling via PCP Proteins Polarize Node Cells for Left-Right Symmetry Breaking
Katsura Minegishi, Masakazu Hashimoto, Rieko Ajima, Katsuyoshi Takaoka, Kyosuke Shinohara, Yayoi Ikawa, Hiromi Nishimura, Andrew P. McMahon, Karl Willert, Yasushi Okada, Hiroshi Sasaki, Dongbo Shi, Toshihiko Fujimori, Toshihisa Ohtsuka, Yasunobu Igarashi, Terry P. Yamaguchi, Akihiko Shimono, Hidetaka Shiratori, Hiroshi Hamada
Dev Cell. Author manuscript; available in PMC 2021 Mar 19.
Published in final edited form as: Dev Cell. 2017 Mar 13; 40(5): 439–452.e4. doi: 10.1016/j.devcel.2017.02.010
PMCID:
PMC7974384
AbstractArticlePDF–3.5M
12.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
13.
Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis
Jiali Ru, Dianlei Guo, Jiaying Fan, Jiao Zhang, Rong Ju, Hong Ouyang, Lai Wei, Yizhi Liu, Chunqiao Liu
Invest Ophthalmol Vis Sci. 2020 Nov; 61(13): 6. Published online 2020 Nov 3. doi: 10.1167/iovs.61.13.6
PMCID:
PMC7645213
AbstractArticlePDF–35M
14.
Dual regulation of planar polarization by secreted Wnts and Vangl2 in the developing mouse cochlea
Elvis Huarcaya Najarro, Jennifer Huang, Adrian Jacobo, Lee A. Quiruz, Nicolas Grillet, Alan G. Cheng
Development. 2020 Oct 1; 147(19): dev191981. Published online 2020 Oct 5. doi: 10.1242/dev.191981
PMCID:
PMC7561480
AbstractArticle
15.
A mammalian Wnt5a–Ror2–Vangl2 axis controls the cytoskeleton and confers cellular properties required for alveologenesis
Kuan Zhang, Erica Yao, Chuwen Lin, Yu-Ting Chou, Julia Wong, Jianying Li, Paul J Wolters, Pao-Tien Chuang
eLife. 2020; 9: e53688. Published online 2020 May 12. doi: 10.7554/eLife.53688
PMCID:
PMC7217702
AbstractArticlePDF–8.0M
16.
Non-canonical Wnt signalling regulates scarring in biliary disease via the planar cell polarity receptors
D. H. Wilson, E. J. Jarman, R. P. Mellin, M. L. Wilson, S. H. Waddell, P. Tsokkou, N. T. Younger, A. Raven, S. R. Bhalla, A. T. R. Noll, S. W. Olde Damink, F. G. Schaap, P. Chen, D. O. Bates, J. M. Banales, C. H. Dean, D. J. Henderson, O. J. Sansom, T. J. Kendall, L. Boulter
Nat Commun. 2020; 11: 445. Published online 2020 Jan 23. doi: 10.1038/s41467-020-14283-3
PMCID:
PMC6978415
AbstractArticlePDF–2.5M
17.
Non-Canonical Wnt-Signaling through Ryk Regulates the Generation of Somatostatin- and Parvalbumin-Expressing Cortical Interneurons
Melissa G. McKenzie, Lucy V. Cobbs, Patrick D. Dummer, Timothy J. Petros, Michael M. Halford, Steven Stacker, Yimin Zou, Gord J. Fishell, Edmund Au
Neuron. Author manuscript; available in PMC 2020 Sep 4.
Published in final edited form as: Neuron. 2019 Sep 4; 103(5): 853–864.e4. Published online 2019 Jun 27. doi: 10.1016/j.neuron.2019.06.003
PMCID:
PMC6728181
AbstractArticlePDF–1.1M
18.
VANGL2 regulates luminal epithelial organization and cell turnover in the mammary gland
Prestina Smith, Nathan Godde, Stefany Rubio, Melawit Tekeste, Eszter K. Vladar, Jeffrey D. Axelrod, Deborah J. Henderson, Michal Milgrom-Hoffman, Patrick O. Humbert, Lindsay Hinck
Sci Rep. 2019; 9: 7079. Published online 2019 May 8. doi: 10.1038/s41598-019-43444-8
PMCID:
PMC6506599
AbstractArticlePDF–2.9M
19.
Mouse screen reveals multiple new genes underlying mouse and human hearing loss
Neil J. Ingham, Selina A. Pearson, Valerie E. Vancollie, Victoria Rook, Morag A. Lewis, Jing Chen, Annalisa Buniello, Elisa Martelletti, Lorenzo Preite, Chi Chung Lam, Felix D. Weiss, Zӧe Powis, Pim Suwannarat, Christopher J. Lelliott, Sally J. Dawson, Jacqueline K. White, Karen P. Steel
PLoS Biol. 2019 Apr; 17(4): e3000194. Published online 2019 Apr 11. doi: 10.1371/journal.pbio.3000194
PMCID:
PMC6459510
AbstractArticlePDF–5.1M
20.
The potassium channel KCNJ13 is essential for smooth muscle cytoskeletal organization during mouse tracheal tubulogenesis
Wenguang Yin, Hyun-Taek Kim, ShengPeng Wang, Felix Gunawan, Lei Wang, Keishi Kishimoto, Hua Zhong, Dany Roman, Jens Preussner, Stefan Guenther, Viola Graef, Carmen Buettner, Beate Grohmann, Mario Looso, Mitsuru Morimoto, Graeme Mardon, Stefan Offermanns, Didier Y. R. Stainier
Nat Commun. 2018; 9: 2815. Published online 2018 Jul 19. doi: 10.1038/s41467-018-05043-5
PMCID:
PMC6052067
AbstractArticlePDF–11M

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