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Select item 110097871.

Characterization of Somatotrope Cell Expansion in Response to GHRH in the Neonatal Mouse Pituitary

Richard L Gonigam, Karen E Weis, Xiyu Ge, Boyuan Yao, Qilin Zhang, Lori T Raetzman

Endocrinology. 2023 Oct; 164(10): bqad131. Published online 2023 Aug 24. doi: 10.1210/endocr/bqad131

PMCID:: PMC11009787

Abstract Article

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 102444283.

Growth hormone releasing hormone signaling promotes Th17 cell differentiation and autoimmune inflammation

Lin Du, Bo Man Ho, Linbin Zhou, Yolanda Wong Ying Yip, Jing Na He, Yingying Wei, Clement C. Tham, Sun On Chan, Andrew V. Schally, Chi Pui Pang, Jian Li, Wai Kit Chu

Nat Commun. 2023; 14: 3298. Published online 2023 Jun 6. doi: 10.1038/s41467-023-39023-1

PMCID:: PMC10244428

Abstract Article PDF–3.0M

Select item 101332064.

Central growth hormone action regulates neuroglial and proinflammatory markers in the hypothalamus of male mice

Frederick Wasinski, Mariana R. Tavares, Daniela O. Gusmao, Edward O. List, John J. Kopchick, Guilherme A. Alves, Renata Frazao, Jose Donato, Jr.

Neurosci Lett. Author manuscript; available in PMC 2024 May 29.

Published in final edited form as: Neurosci Lett. 2023 May 29; 806: 137236. Published online 2023 Apr 6. doi: 10.1016/j.neulet.2023.137236

PMCID:: PMC10133206

Abstract Article PDF–845K

Select item 98460435.

Growth hormone stimulates lipolysis in mice but not in adipose tissue or adipocyte culture

Lidan Zhao, Honglin Jiang

Front Endocrinol (Lausanne) 2022; 13: 1028191. Published online 2023 Jan 4. doi: 10.3389/fendo.2022.1028191

PMCID:: PMC9846043

Abstract Article PDF–3.3M

Select item 87826086.

FOXO Transcription Factors Are Required for Normal Somatotrope Function and Growth

Caitlin E Stallings, Jyoti Kapali, Brian W Evans, Stacey R McGee, Buffy S Ellsworth

Endocrinology. 2022 Feb; 163(2): bqab263. Published online 2021 Dec 31. doi: 10.1210/endocr/bqab263

PMCID:: PMC8782608

Abstract Article

Select item 81526047.

Early Life Nociception is Influenced by Peripheral Growth Hormone Signaling

Adam J. Dourson, Zachary K. Ford, Kathryn J. Green, Carolyn E. McCrossan, Megan C. Hofmann, Renita C. Hudgins, Michael P. Jankowski

J Neurosci. 2021 May 19; 41(20): 4410–4427. doi: 10.1523/JNEUROSCI.3081-20.2021

PMCID:: PMC8152604

Abstract Article PDF–4.4M

Select item 71765508.

Growth hormone receptor deletion reduces the density of axonal projections from hypothalamic arcuate nucleus neurons

Frederick Wasinski, Isadora C. Furigo, Pryscila D.S. Teixeira, Angela M. Ramos-Lobo, Cibele N. Peroni, Paolo Bartolini, Edward O. List, John J. Kopchick, Jose Donato, Jr.

Neuroscience. Author manuscript; available in PMC 2021 May 10.

Published in final edited form as: Neuroscience. 2020 May 10; 434: 136–147. Published online 2020 Mar 27. doi: 10.1016/j.neuroscience.2020.03.037

PMCID:: PMC7176550

Abstract Article PDF–3.3M

Select item 55032619.

Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program

John P. Sundberg, Soheil S. Dadras, Kathleen A. Silva, Victoria E. Kennedy, Gaven Garland, Stephen A. Murray, Beth A. Sundberg, Paul N. Schofield, C. Herbert Pratt

PLoS One. 2017; 12(7): e0180682. Published online 2017 Jul 10. doi: 10.1371/journal.pone.0180682

PMCID:: PMC5503261

Abstract Article PDF–31M

Select item 529582110.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 508653811.

Foxo1 Is Required for Normal Somatotrope Differentiation

Jyoti Kapali, Brock E. Kabat, Kelly L. Schmidt, Caitlin E. Stallings, Mason Tippy, Deborah O. Jung, Brian S. Edwards, Leah B. Nantie, Lori T. Raeztman, Amy M. Navratil, Buffy S. Ellsworth

Endocrinology. 2016 Nov; 157(11): 4351–4363. Published online 2016 Sep 15. doi: 10.1210/en.2016-1372

PMCID:: PMC5086538

Abstract Article

Select item 473475312.

Weak Epistasis Generally Stabilizes Phenotypes in a Mouse Intercross

Anna L. Tyler, Leah Rae Donahue, Gary A. Churchill, Gregory W. Carter

PLoS Genet. 2016 Feb; 12(2): e1005805. Published online 2016 Feb 1. doi: 10.1371/journal.pgen.1005805

PMCID:: PMC4734753

Abstract Article PDF–1.9M

Select item 457245513.

The somatotropic axis and longevity in mice

H. M. Brown-Borg

Am J Physiol Endocrinol Metab. 2015 Sep 15; 309(6): E503–E510. Published online 2015 Jul 28. doi: 10.1152/ajpendo.00262.2015

PMCID:: PMC4572455

Abstract Article

Select item 448913314.

FOXL2 modulates cartilage, skeletal development and IGF1-dependent growth in mice

Mara Marongiu, Loredana Marcia, Emanuele Pelosi, Mario Lovicu, Manila Deiana, Yonqing Zhang, Alessandro Puddu, Angela Loi, Manuela Uda, Antonino Forabosco, David Schlessinger, Laura Crisponi

BMC Dev Biol. 2015; 15: 27. Published online 2015 Jul 2. doi: 10.1186/s12861-015-0072-y

PMCID:: PMC4489133

Abstract Article PDF–3.2M

Select item 426057115.

Agonists of growth hormone-releasing hormone stimulate self-renewal of cardiac stem cells and promote their survival

Victoria Florea, Sonia S. Majid, Rosemeire M. Kanashiro-Takeuchi, Ren-Zhi Cai, Norman L. Block, Andrew V. Schally, Joshua M. Hare, Claudia O. Rodrigues

Proc Natl Acad Sci U S A. 2014 Dec 2; 111(48): 17260–17265. Published online 2014 Nov 17. doi: 10.1073/pnas.1420375111

PMCID:: PMC4260571

Abstract Article PDF–969K

Select item 425436316.

Genetic background determines if Stat5b suppresses or enhances murine hepatocarcinogenesis

Christopher Oberley, Andrea Bilger, Norman R. Drinkwater

Mol Carcinog. Author manuscript; available in PMC 2015 Oct 1.

Published in final edited form as: Mol Carcinog. 2015 Oct; 54(10): 959–970. Published online 2014 May 17. doi: 10.1002/mc.22165

PMCID:: PMC4254363

Abstract Article PDF–744K

Select item 396495517.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 388268418.

ENU mutation mapped to a distal region of chromosome 11 is a major determinant of bone size

Bouchra Edderkaoui, Chandrasekhar Kesavan, David J. Baylink, Jon E. Wergedal, Apurva K. Srivastava, Subburaman Mohan

Physiol Genomics. 2013 Dec 15; 45(24): 1222–1228. Published online 2013 Oct 22. doi: 10.1152/physiolgenomics.00142.2013

PMCID:: PMC3882684

Abstract Article

Select item 385719819.

Hepatic-Specific Accessibility of Igf1 Gene Enhancers Is Independent of Growth Hormone Signaling

Mahalakshmi Santhanam, Dennis J. Chia

Mol Endocrinol. 2013 Dec; 27(12): 2080–2092. Published online 2013 Oct 9. doi: 10.1210/me.2013-1181

PMCID:: PMC3857198

Abstract Article

Select item 364986120.

FXR inhibits gankyrin in mouse livers and prevents development of liver cancer

Yanjun Jiang, Polina Iakova, Jingling Jin, Emily Sullivan, Vladislav Sharin, Il-Hwa Hong, Sayee Anakk, Angela Mayor, Gretchen Darlington, Milton Finegold, David Moore, Nikolai A. Timchenko

Hepatology. Author manuscript; available in PMC 2014 Mar 1.

Published in final edited form as: Hepatology. 2013 Mar; 57(3): 1098–1106. Published online 2013 Feb 15. doi: 10.1002/hep.26146

PMCID:: PMC3649861

Abstract Article PDF–2.7M

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