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Select item 116291601.

DEC1 deficiency protects against bone loss induced by ovariectomy by inhibiting inflammation

Lan Lin, Zhiyi Qiang, Kaiao Chen, Ying Huo, Wei Liu, Jian Yang

J Biomed Res. 2024 Nov; 38(6): 613–627. Published online 2024 May 29. doi: 10.7555/JBR.38.20240069

PMCID:: PMC11629160

Abstract Article PDF–76M

Select item 109177802.

BHLHE40/41 regulate microglia and peripheral macrophage responses associated with Alzheimer’s disease and other disorders of lipid-rich tissues

Anna Podleśny-Drabiniok, Gloriia Novikova, Yiyuan Liu, Josefine Dunst, Rose Temizer, Chiara Giannarelli, Samuele Marro, Taras Kreslavsky, Edoardo Marcora, Alison Mary Goate

Nat Commun. 2024; 15: 2058. Published online 2024 Mar 6. doi: 10.1038/s41467-024-46315-7

PMCID:: PMC10917780

Abstract Article PDF–4.5M

Select item 109176603.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 108944724.

Bhlhe40 deficiency attenuates LPS-induced acute lung injury through preventing macrophage pyroptosis

Xingxing Hu, Menglin Zou, Weishuai Zheng, Minghui Zhu, Qinhui Hou, Han Gao, Xin Zhang, Yuan Liu, Zhenshun Cheng

Respir Res. 2024; 25: 100. Published online 2024 Feb 24. doi: 10.1186/s12931-024-02740-2

PMCID:: PMC10894472

Abstract Article PDF–7.5M

Select item 108467035.

BHLHE40 drives protective polyfunctional CD4 T cell differentiation in the female reproductive tract against Chlamydia

Miguel A. B. Mercado, Qiang Li, Charles M. Quick, Yejin Kim, Rachel Palmer, Lu Huang, Lin-Xi Li

PLoS Pathog. 2024 Jan; 20(1): e1011983. Published online 2024 Jan 25. doi: 10.1371/journal.ppat.1011983

PMCID:: PMC10846703

Abstract Article PDF–2.9M

Select item 107630666.

Loss of Dec1 inhibits alcohol-induced hepatic lipid accumulation and circadian rhythm disorder

Fuyuki Sato, Ujjal K. Bhawal, Kosuke Oikawa, Yasuteru Muragaki

BMC Mol Cell Biol. 2024; 25: 1. Published online 2024 Jan 2. doi: 10.1186/s12860-023-00497-y

PMCID:: PMC10763066

Abstract Article PDF–3.8M

Select item 106954127.

BHLHE40 Mediates Cross-Talk between Pathogenic T_H17 Cells and Myeloid Cells during Experimental Autoimmune Encephalomyelitis

Melissa E. Cook, Irina Shchukina, Chih-Chung Lin, Tara R. Bradstreet, Elizabeth A. Schwarzkopf, Nicholas N. Jarjour, Ashlee M. Webber, Konstantin Zaitsev, Maxim N. Artyomov, Brian T. Edelson

Immunohorizons. 2023 Nov; 7(11): 737–746. Published online 2023 Nov 7. doi: 10.4049/immunohorizons.2300042

PMCID:: PMC10695412

Abstract Article PDF–4.3M

Select item 106875328.

Cisplatin increases carboxylesterases through increasing PXR mediated by the decrease of DEC1

Minqin Xu, Lihua Zhang, Lan Lin, Zhiyi Qiang, Wei Liu, Jian Yang

J Biomed Res. 2023 Nov; 37(6): 431–447. Published online 2023 Nov 15. doi: 10.7555/JBR.37.20230047

PMCID:: PMC10687532

Abstract Article PDF–13M

Select item 106529039.

Bhlhe40 limits early IL-10 production from CD4⁺ T cells during Plasmodium yoelii 17X infection

Kara A. O'Neal, Sheldon L. Zeltner, Camille L. Foscue, Jason S. Stumhofer

Infect Immun. 2023 Nov; 91(11): e00367-23. Published online 2023 Oct 16. doi: 10.1128/iai.00367-23

PMCID:: PMC10652903

Abstract Article PDF–5.4M

Select item 1039866410.

Hypoxia causes pancreatic β‐cell dysfunction and impairs insulin secretion by activating the transcriptional repressor BHLHE40

Tomonori Tsuyama, Yoshifumi Sato, Tatsuya Yoshizawa, Takaaki Matsuoka, Kazuya Yamagata

EMBO Rep. 2023 Aug; 24(8): e56227. Published online 2023 Jun 21. doi: 10.15252/embr.202256227

PMCID:: PMC10398664

Abstract Article PDF–3.0M

Select item 1039049211.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 1002055912.

A differentiation roadmap of murine placentation at single-cell resolution

Xiangxiang Jiang, Yue Wang, Zhenyu Xiao, Long Yan, Shanshan Guo, Yiming Wang, Hao Wu, Xuehan Zhao, Xiaoyin Lu, Hongmei Wang

Cell Discov. 2023; 9: 30. Published online 2023 Mar 17. doi: 10.1038/s41421-022-00513-z

PMCID:: PMC10020559

Abstract Article PDF–5.8M

Select item 1001183013.

Differentiated embryonic chondrocyte expressed gene-1 is a central signaling component in the development of collagen-induced rheumatoid arthritis

Yichen Wu, Haobin Wang, Ying Huo, Bingfang Yan, Hiroaki Honda, Wei Liu, Jian Yang

J Biol Chem. 2023 Mar; 299(3): 102982. Published online 2023 Feb 3. doi: 10.1016/j.jbc.2023.102982

PMCID:: PMC10011830

Abstract Article PDF–5.6M

Select item 995046514.

Cholinergic control of Th17 cell pathogenicity in experimental autoimmune encephalomyelitis

Robert Nechanitzky, Duygu Nechanitzky, Parameswaran Ramachandran, Gordon S. Duncan, Chunxing Zheng, Christoph Göbl, Kyle T. Gill, Jillian Haight, Andrew C. Wakeham, Bryan E. Snow, Vivian Bradaschia-Correa, Milan Ganguly, Zhibin Lu, Mary E. Saunders, Richard A. Flavell, Tak W. Mak

Cell Death Differ. 2023 Feb; 30(2): 407–416. Published online 2022 Dec 17. doi: 10.1038/s41418-022-01092-y

PMCID:: PMC9950465

Abstract Article PDF–2.8M

Select item 982032215.

Ribosomal Stress Couples with the Hypoxia Response in Dec1-Dependent Orthodontic Tooth Movement

Shigeru Nakamura, Keiji Tanimoto, Ujjal K. Bhawal

Int J Mol Sci. 2023 Jan; 24(1): 618. Published online 2022 Dec 29. doi: 10.3390/ijms24010618

PMCID:: PMC9820322

Abstract Article PDF–16M

Select item 938646416.

The conserved Mediator subunit cyclin C (CCNC) is required for brown adipocyte development and lipid accumulation

Ziyi Song, Alus M. Xiaoli, Youlei Li, Gerile Siqin, Tian Wu, Randy Strich, Jeffrey E. Pessin, Fajun Yang

Mol Metab. 2022 Oct; 64: 101548. Published online 2022 Jul 19. doi: 10.1016/j.molmet.2022.101548

PMCID:: PMC9386464

Abstract Article PDF–6.6M

Select item 898091217.

DEC1 promotes progression of Helicobacter pylori‐positive gastric cancer by regulating Akt/NF‐κB pathway

Yanfei Jia, Yanyan Liu, Jingyu Zhu, Liang Liu, Xiaoli Ma, Duanrui Liu, Shuyi Han, Lulu Zhang, Zhi‐Qiang Ling, Yunshan Wang

J Cell Mol Med. 2022 Apr; 26(7): 1943–1954. Published online 2022 Feb 4. doi: 10.1111/jcmm.17219

PMCID:: PMC8980912

Abstract Article PDF–2.2M

Select item 895985418.

Dec1 Deficiency Ameliorates Pulmonary Fibrosis Through the PI3K/AKT/GSK-3β/β-Catenin Integrated Signaling Pathway

Xingxing Hu, Menglin Zou, Lan Ni, Mingyang Zhang, Weishuai Zheng, Bing Liu, Zhenshun Cheng

Front Pharmacol. 2022; 13: 829673. Published online 2022 Mar 9. doi: 10.3389/fphar.2022.829673

PMCID:: PMC8959854

Abstract Article PDF–9.6M

Select item 868966519.

Bhlhe40 function in activated B and T_FH cells restrains the GC reaction and prevents lymphomagenesis

René Rauschmeier, Annika Reinhardt, Charlotte Gustafsson, Vassilis Glaros, Artem V. Artemov, Josefine Dunst, Reshma Taneja, Igor Adameyko, Robert Månsson, Meinrad Busslinger, Taras Kreslavsky

J Exp Med. 2022 Feb 7; 219(2): e20211406. Published online 2021 Dec 17. doi: 10.1084/jem.20211406

PMCID:: PMC8689665

Abstract Article PDF–8.0M

Select item 860735520.

BHLHE40 promotes macrophage pro-inflammatory gene expression and functions

Atif Zafar, Hang Pong Ng, Gun-Dong Kim, E. Ricky Chan, Ganapati H. Mahabeleshwar

FASEB J. Author manuscript; available in PMC 2022 Oct 1.

Published in final edited form as: FASEB J. 2021 Oct; 35(10): e21940. doi: 10.1096/fj.202100944R

PMCID:: PMC8607355

Abstract Article PDF–3.0M

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