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Select item 115737891.

Accurate and sensitive interactome profiling using a quantitative protein-fragment complementation assay

Natalia Lazarewicz, Gaëlle Le Dez, Romina Cerjani, Lunelys Runeshaw, Matthias Meurer, Michael Knop, Robert Wysocki, Gwenaël Rabut

Cell Rep Methods. 2024 Oct 21; 4(10): 100880. Published online 2024 Oct 21. doi: 10.1016/j.crmeth.2024.100880

PMCID:: PMC11573789

Abstract Article PDF–4.0M

Select item 114236782.

An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae

Yasmina Filali-Mouncef, Alexandre Leytens, Prado Vargas Duarte, Mattia Zampieri, Jörn Dengjel, Fulvio Reggiori

Autophagy. 2024; 20(10): 2323–2337. Published online 2024 Jul 3. doi: 10.1080/15548627.2024.2366749

PMCID:: PMC11423678

Abstract Article PDF–1.7M

Select item 113624593.

The novel ribosome biogenesis inhibitor usnic acid blocks nucleolar pre-60S maturation

Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler

Nat Commun. 2024; 15: 7511. Published online 2024 Aug 29. doi: 10.1038/s41467-024-51754-3

PMCID:: PMC11362459

Abstract Article PDF–3.5M

Select item 112946054.

Receptor-mediated cargo hitchhiking on bulk autophagy

Eigo Takeda, Takahiro Isoda, Sachiko Hosokawa, Yu Oikawa, Shukun Hotta-Ren, Alexander I May, Yoshinori Ohsumi

EMBO J. 2024 Aug; 43(15): 3116–3140. Published online 2024 May 16. doi: 10.1038/s44318-024-00091-8

PMCID:: PMC11294605

Abstract Article PDF–5.6M

Select item 110241855.

The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis

Victor E. Cruz, Christine S. Weirich, Nagesh Peddada, Jan P. Erzberger

Nat Commun. 2024; 15: 3296. Published online 2024 Apr 17. doi: 10.1038/s41467-024-47616-7

PMCID:: PMC11024185

Abstract Article PDF–7.4M

Select item 108687276.

Adaptive preservation of orphan ribosomal proteins in chaperone-dispersed condensates

Asif Ali, Rania Garde, Olivia C. Schaffer, Jared A. M. Bard, Kabir Husain, Samantha Keyport Kik, Kathleen A. Davis, Sofia Luengo-Woods, Maya G. Igarashi, D. Allan Drummond, Allison H. Squires, David Pincus

Nat Cell Biol. Author manuscript; available in PMC 2024 Feb 15.

Published in final edited form as: Nat Cell Biol. 2023 Nov; 25(11): 1691–1703. Published online 2023 Oct 16. doi: 10.1038/s41556-023-01253-2

PMCID:: PMC10868727

Abstract Article PDF–7.0M

Select item 107700427.

Nuclear Hsp104 safeguards the dormant translation machinery during quiescence

Verena Kohler, Andreas Kohler, Lisa Larsson Berglund, Xinxin Hao, Sarah Gersing, Axel Imhof, Thomas Nyström, Johanna L. Höög, Martin Ott, Claes Andréasson, Sabrina Büttner

Nat Commun. 2024; 15: 315. Published online 2024 Jan 5. doi: 10.1038/s41467-023-44538-8

PMCID:: PMC10770042

Abstract Article PDF–5.1M

Select item 107001388.

The social and structural architecture of the yeast protein interactome

André C. Michaelis, Andreas-David Brunner, Maximilian Zwiebel, Florian Meier, Maximilian T. Strauss, Isabell Bludau, Matthias Mann

Nature. 2023; 624(7990): 192–200. Published online 2023 Nov 15. doi: 10.1038/s41586-023-06739-5

PMCID:: PMC10700138

Abstract Article PDF–20M

Select item 98363489.

A synthetic genetic array screen for interactions with the RNA helicase DED1 during cell stress in budding yeast

Sara B Carey, Hannah M List, Ashwin Siby, Paolo Guerra, Timothy A Bolger

G3 (Bethesda) 2023 Jan; 13(1): jkac296. Published online 2022 Nov 21. doi: 10.1093/g3journal/jkac296

PMCID:: PMC9836348

Abstract Article PDF–857K

Select item 963098610.

A balancing act: interactions within NuA4/TIP60 regulate picNuA4 function in Saccharomyces cerevisiae and humans

Phoebe Y T Lu, Alyssa C Kirlin, Maria J Aristizabal, Hilary T Brewis, Nancy Lévesque, Dheva T Setiaputra, Nikita Avvakumov, Joris J Benschop, Marian Groot Koerkamp, Frank C P Holstege, Nevan J Krogan, Calvin K Yip, Jacques Côté, Michael S Kobor

Genetics. 2022 Nov; 222(3): iyac136. Published online 2022 Sep 6. doi: 10.1093/genetics/iyac136

PMCID:: PMC9630986

Abstract Article PDF–2.2M

Select item 937189211.

mRNA- and factor-driven dynamic variability controls eIF4F-cap recognition for translation initiation

Burak Çetin, Seán E O’Leary

Nucleic Acids Res. 2022 Aug 12; 50(14): 8240–8261. Published online 2022 Jul 25. doi: 10.1093/nar/gkac631

PMCID:: PMC9371892

Abstract Article PDF–5.7M

Select item 920981112.

New data and collaborations at the Saccharomyces Genome Database: updated reference genome, alleles, and the Alliance of Genome Resources

Stacia R Engel, Edith D Wong, Robert S Nash, Suzi Aleksander, Micheal Alexander, Eric Douglass, Kalpana Karra, Stuart R Miyasato, Matt Simison, Marek S Skrzypek, Shuai Weng, J Michael Cherry

Genetics. 2022 Apr; 220(4): iyab224. Published online 2021 Dec 13. doi: 10.1093/genetics/iyab224

PMCID:: PMC9209811

Abstract Article PDF–818K

Select item 916991313.

The ubiquitin–proteasome system regulates meiotic chromosome organization

Xiao Yang, Meihui Song, Ying Wang, Taicong Tan, Zhongyu Tian, Binyuan Zhai, Xuan Yang, Yingjin Tan, Yanding Cao, Shaojun Dai, Shunxin Wang, Liangran Zhang

Proc Natl Acad Sci U S A. 2022 Apr 26; 119(17): e2106902119. Published online 2022 Apr 19. doi: 10.1073/pnas.2106902119

PMCID:: PMC9169913

Abstract Article PDF–2.1M

Select item 888165214.

The cap-proximal RNA secondary structure inhibits preinitiation complex formation on HAC1 mRNA

Jagadeesh Kumar Uppala, Leena Sathe, Abhijit Chakraborty, Sankhajit Bhattacharjee, Anthony Thomas Pulvino, Madhusudan Dey

J Biol Chem. 2022 Mar; 298(3): 101648. Published online 2022 Jan 28. doi: 10.1016/j.jbc.2022.101648

PMCID:: PMC8881652

Abstract Article PDF–3.5M

Select item 880492915.

Oxidative stress protein Oxr1 promotes V‐ATPase holoenzyme disassembly in catalytic activity‐independent manner

Md. Murad Khan, Seowon Lee, Sergio Couoh‐Cardel, Rebecca A Oot, Hyunmin Kim, Stephan Wilkens, Soung‐Hun Roh

EMBO J. 2022 Feb 1; 41(3): e109360. Published online 2021 Dec 17. doi: 10.15252/embj.2021109360

PMCID:: PMC8804929

Abstract Article PDF–5.5M

Select item 842121416.

eIF4G is retained on ribosomes elongating and terminating on short upstream ORFs to control reinitiation in yeast

Mahabub Pasha Mohammad, Anna Smirnova, Stanislava Gunišová, Leoš Shivaya Valášek

Nucleic Acids Res. 2021 Sep 7; 49(15): 8743–8756. Published online 2021 Aug 5. doi: 10.1093/nar/gkab652

PMCID:: PMC8421214

Abstract Article PDF–872K

Select item 809411717.

SUMOylation stabilizes sister kinetochore biorientation to allow timely anaphase

Xue Bessie Su, Menglu Wang, Claudia Schaffner, Olga O. Nerusheva, Dean Clift, Christos Spanos, David A. Kelly, Michael Tatham, Andreas Wallek, Yehui Wu, Juri Rappsilber, A. Arockia Jeyaprakash, Zuzana Storchova, Ronald T. Hay, Adèle L. Marston

J Cell Biol. 2021 Jul 5; 220(7): e202005130. Published online 2021 Apr 30. doi: 10.1083/jcb.202005130