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Items: 1 to 20 of 46

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function
Sina Jami, Jennifer R. Deuis, Tabea Klasfauseweh, Xiaoyang Cheng, Sergey Kurdyukov, Felicity Chung, Andrei L. Okorokov, Shengnan Li, Jiangtao Zhang, Ben Cristofori-Armstrong, Mathilde R. Israel, Robert J. Ju, Samuel D. Robinson, Peng Zhao, Lotten Ragnarsson, Åsa Andersson, Poanna Tran, Vanessa Schendel, Kirsten L. McMahon, Hue N. T. Tran, Yanni K.-Y. Chin, Yifei Zhu, Junyu Liu, Theo Crawford, Saipriyaa Purushothamvasan, Abdella M. Habib, David A. Andersson, Lachlan D. Rash, John N. Wood, Jing Zhao, Samantha J. Stehbens, Mehdi Mobli, Andreas Leffler, Daohua Jiang, James J. Cox, Stephen G. Waxman, Sulayman D. Dib-Hajj, G. Gregory Neely, Thomas Durek, Irina Vetter
Nat Commun. 2023; 14: 2442. Published online 2023 Apr 28. doi: 10.1038/s41467-023-37963-2
PMCID:
PMC10147923
AbstractArticlePDF–3.8M
3.
Single-cell RNA-sequencing analysis of the developing mouse inner ear identifies molecular logic of auditory neuron diversification
Charles Petitpré, Louis Faure, Phoebe Uhl, Paula Fontanet, Iva Filova, Gabriela Pavlinkova, Igor Adameyko, Saida Hadjab, Francois Lallemend
Nat Commun. 2022; 13: 3878. Published online 2022 Jul 5. doi: 10.1038/s41467-022-31580-1
PMCID:
PMC9256748
AbstractArticlePDF–3.9M
4.
The Gain-of-Function R222S Variant in Scn11a Contributes to Visceral Hyperalgesia and Intestinal Dysmotility in Scn11aR222S/R222S Mice
Chenyu Zhao, Jishuo Jin, Haoye Hu, Xi Zhou, Xiaoliu Shi
Front Neurol. 2022; 13: 856459. Published online 2022 May 27. doi: 10.3389/fneur.2022.856459
PMCID:
PMC9197071
AbstractArticlePDF–917K
5.
Selective disruption of trigeminal sensory neurogenesis and differentiation in a mouse model of 22q11.2 deletion syndrome
Beverly A. Karpinski, Thomas M. Maynard, Corey A. Bryan, Gelila Yitsege, Anelia Horvath, Norman H. Lee, Sally A. Moody, Anthony-Samuel LaMantia
Dis Model Mech. 2022 Feb 1; 15(2): dmm047357. Published online 2021 May 4. doi: 10.1242/dmm.047357
PMCID:
PMC8126478
AbstractArticle
6.
SCN11A gene deletion causes sensorineural hearing loss by impairing the ribbon synapses and auditory nerves
Mian Zu, Wei-Wei Guo, Tao Cong, Fei Ji, Shi-Li Zhang, Yue Zhang, Xin Song, Wei Sun, David Z. Z. He, Wei-Guo Shi, Shi-Ming Yang
BMC Neurosci. 2021; 22: 18. Published online 2021 Mar 22. doi: 10.1186/s12868-021-00613-8
PMCID:
PMC7986359
AbstractArticlePDF–2.1M
7.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
8.
Gain-of-function mutation in SCN11A causes itch and affects neurogenic inflammation and muscle function in Scn11a+/L799P mice
Matthias Ebbinghaus, Lorena Tuchscherr, Gisela Segond von Banchet, Lutz Liebmann, Volker Adams, Mieczyslaw Gajda, Christian A. Hübner, Ingo Kurth, Hans-Georg Schaible
PLoS One. 2020; 15(8): e0237101. Published online 2020 Aug 20. doi: 10.1371/journal.pone.0237101
PMCID:
PMC7440628
AbstractArticlePDF–2.5M
9.
An enhancer cluster controls gene activity and topology of the SCN5A-SCN10A locus in vivo
Joyce C. K. Man, Rajiv A. Mohan, Malou van den Boogaard, Catharina R. E. Hilvering, Catherine Jenkins, Vincent Wakker, Valerio Bianchi, Wouter de Laat, Phil Barnett, Bastiaan J. Boukens, Vincent M. Christoffels
Nat Commun. 2019; 10: 4943. Published online 2019 Oct 30. doi: 10.1038/s41467-019-12856-5
PMCID:
PMC6821807
AbstractArticlePDF–2.9M
10.
Maladaptive activation of Nav1.9 channels by nitric oxide causes triptan-induced medication overuse headache
Caroline Bonnet, Jizhe Hao, Nancy Osorio, Anne Donnet, Virginie Penalba, Jérôme Ruel, Patrick Delmas
Nat Commun. 2019; 10: 4253. Published online 2019 Sep 18. doi: 10.1038/s41467-019-12197-3
Correction in:
Nat Commun. 2021; 12: 6952.
PMCID:
PMC6751217
AbstractArticlePDF–3.8M
11.
ZBTB20 regulates nociception and pain sensation by modulating TRP channel expression in nociceptive sensory neurons
An-Jing Ren, Kai Wang, Huan Zhang, Anjun Liu, Xianhua Ma, Qing Liang, Dongmei Cao, John N. Wood, David Z. He, Yu-Qiang Ding, Wen-Jun Yuan, Zhifang Xie, Weiping J. Zhang
Nat Commun. Author manuscript; available in PMC 2019 Aug 8.
Published in final edited form as: Nat Commun. 2014 Nov 5; 5: 4984. Published online 2014 Nov 5. doi: 10.1038/ncomms5984
PMCID:
PMC6687506
AbstractArticlePDF–3.4M
12.
The Voltage-Gated Sodium Channel Nav1.9 Is an Effector of Peripheral Inflammatory Pain Hypersensitivity
Fumimasa Amaya, Haibin Wang, Michael Costigan, Andrew J. Allchorne, Jon P. Hatcher, Julie Egerton, Tania Stean, Valerie Morisset, David Grose, Martin J. Gunthorpe, Iain P. Chessell, Simon Tate, Paula J. Green, Clifford J. Woolf
J Neurosci. 2006 Dec 13; 26(50): 12852–12860. doi: 10.1523/JNEUROSCI.4015-06.2006
PMCID:
PMC6674969
AbstractArticlePDF–550K
13.
Early Development of Electrical Excitability in the Mouse Enteric Nervous System
Marlene M. Hao, Alan E. Lomax, Sonja J. McKeown, Christopher A. Reid, Heather M. Young, Joel C. Bornstein
J Neurosci. 2012 Aug 8; 32(32): 10949–10960. doi: 10.1523/JNEUROSCI.1426-12.2012
PMCID:
PMC6621017
AbstractArticlePDF–2.3M
14.
Specialized Functions of Nav1.5 and Nav1.9 Channels in Electrogenesis of Myenteric Neurons in Intact Mouse Ganglia
Nancy Osorio, Sergiy Korogod, Patrick Delmas
J Neurosci. 2014 Apr 9; 34(15): 5233–5244. doi: 10.1523/JNEUROSCI.0057-14.2014
PMCID:
PMC6609004
AbstractArticlePDF–3.2M
15.
An Atoh1-S193A Phospho-Mutant Allele Causes Hearing Deficits and Motor Impairment
Wei Rose Xie, Hsin-I Jen, Michelle L. Seymour, Szu-Ying Yeh, Fred A. Pereira, Andrew K. Groves, Tiemo J. Klisch, Huda Y. Zoghbi
J Neurosci. 2017 Sep 6; 37(36): 8583–8594. doi: 10.1523/JNEUROSCI.0295-17.2017
PMCID:
PMC6596675
AbstractArticlePDF–2.5M
16.
Familial episodic limb pain in kindreds with novel Nav1.9 mutations
Risako Kabata, Hiroko Okuda, Atsuko Noguchi, Daiki Kondo, Michimasa Fujiwara, Kenichiro Hata, Yoshifumi Kato, Ken Ishikawa, Manabu Tanaka, Yuji Sekine, Nozomi Hishikawa, Tomoyuki Mizukami, Junichi Ito, Manami Akasaka, Ken Sakurai, Takeshi Yoshida, Hironori Minoura, Takashi Hayashi, Kohei Inoshita, Misayo Matsuyama, Noriko Kinjo, Yang Cao, Sumiko Inoue, Hatasu Kobayashi, Kouji H. Harada, Shohab Youssefian, Tsutomu Takahashi, Akio Koizumi
PLoS One. 2018; 13(12): e0208516. Published online 2018 Dec 17. doi: 10.1371/journal.pone.0208516
PMCID:
PMC6296736
AbstractArticlePDF–1.6M
17.
A disease mutation reveals a role for NaV1.9 in acute itch
Juan Salvatierra, Marcelo Diaz-Bustamante, James Meixiong, Elaine Tierney, Xinzhong Dong, Frank Bosmans
J Clin Invest. 2018 Dec 3; 128(12): 5434–5447. Published online 2018 Nov 5. doi: 10.1172/JCI122481
PMCID:
PMC6264633
AbstractArticlePDF–6.3M
18.
Heat-resistant action potentials require TTX-resistant sodium channels NaV1.8 and NaV1.9
Filip Touska, Brian Turnquist, Viktorie Vlachova, Peter W. Reeh, Andreas Leffler, Katharina Zimmermann
J Gen Physiol. 2018 Aug 6; 150(8): 1125–1144. doi: 10.1085/jgp.201711786
PMCID:
PMC6080895
AbstractArticlePDF–3.4M
19.
Sodium Channel Nav1.8 Underlies TTX-Resistant Axonal Action Potential Conduction in Somatosensory C-Fibers of Distal Cutaneous Nerves
Amanda H. Klein, Alina Vyshnevska, Timothy V. Hartke, Roberto De Col, Joseph L. Mankowski, Brian Turnquist, Frank Bosmans, Peter W. Reeh, Martin Schmelz, Richard W. Carr, Matthias Ringkamp
J Neurosci. 2017 May 17; 37(20): 5204–5214. doi: 10.1523/JNEUROSCI.3799-16.2017
PMCID:
PMC5444201
AbstractArticlePDF–2.4M
20.
Infantile Pain Episodes Associated with Novel Nav1.9 Mutations in Familial Episodic Pain Syndrome in Japanese Families
Hiroko Okuda, Atsuko Noguchi, Hatasu Kobayashi, Daiki Kondo, Kouji H. Harada, Shohab Youssefian, Hirotomo Shioi, Risako Kabata, Yuki Domon, Kazufumi Kubota, Yutaka Kitano, Yasunori Takayama, Toshiaki Hitomi, Kousaku Ohno, Yoshiaki Saito, Takeshi Asano, Makoto Tominaga, Tsutomu Takahashi, Akio Koizumi
PLoS One. 2016; 11(5): e0154827. Published online 2016 May 25. doi: 10.1371/journal.pone.0154827
PMCID:
PMC4880298
AbstractArticlePDF–1.1M

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