PMC Links for GEO Profiles (Select 11443601) - PMC

Srinivas D. Sithu, Marina V. Malovichko, Krista A. Riggs, Nalinie S. Wickramasinghe, Millicent G. Winner, Abhinav Agarwal, Rihab E. Hamed-Berair, Anuradha Kalani, Daniel W. Riggs, Aruni Bhatnagar, Sanjay Srivastava

JCI Insight. 2017 May 4; 2(9): e86442. Published online 2017 May 4. doi: 10.1172/jci.insight.86442

PMCID:: PMC5414561

Abstract Article PDF–1.3M

Select item 49582814.

A lipidomics study reveals hepatic lipid signatures associating with deficiency of the LDL receptor in a rat model

Hong Yu Wang, Chao Quan, Chunxiu Hu, Bingxian Xie, Yinan Du, Liang Chen, Wei Yang, Liu Yang, Qiaoli Chen, Bin Shen, Bian Hu, Zhihong Zheng, Haibo Zhu, Xingxu Huang, Guowang Xu, Shuai Chen

Biol Open. 2016 Jul 15; 5(7): 979–986. Published online 2016 Jul 4. doi: 10.1242/bio.019802

PMCID:: PMC4958281

Abstract Article PDF–807K

Select item 49458435.

Intrauterine growth restriction combined with a maternal high‐fat diet increases hepatic cholesterol and low‐density lipoprotein receptor activity in rats

Erin K. Zinkhan, Jennifer M. Zalla, Jeanette R. Carpenter, Baifeng Yu, Xing Yu, Gary Chan, Lisa Joss‐Moore, Robert H. Lane

Physiol Rep. 2016 Jul; 4(13): e12862. Published online 2016 Jul 12. doi: 10.14814/phy2.12862

PMCID:: PMC4945843

Abstract Article PDF–1.4M

Select item 47929636.

CCC- and WASH-mediated endosomal sorting of LDLR is required for normal clearance of circulating LDL

Paulina Bartuzi, Daniel D. Billadeau, Robert Favier, Shunxing Rong, Daphne Dekker, Alina Fedoseienko, Hille Fieten, Melinde Wijers, Johannes H. Levels, Nicolette Huijkman, Niels Kloosterhuis, Henk van der Molen, Gemma Brufau, Albert K. Groen, Alison M. Elliott, Jan Albert Kuivenhoven, Barbara Plecko, Gernot Grangl, Julie McGaughran, Jay D. Horton, Ezra Burstein, Marten H. Hofker, Bart van de Sluis

Nat Commun. 2016; 7: 10961. Published online 2016 Mar 11. doi: 10.1038/ncomms10961

PMCID:: PMC4792963

Abstract Article PDF–2.4M

Select item 43050407.

MicroRNA 302a is a novel modulator of cholesterol homeostasis and atherosclerosis

Svenja Meiler, Yvonne Baumer, Emma Toulmin, Kosal Seng, William A. Boisvert

Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2016 Feb 1.

Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Feb; 35(2): 323–331. Published online 2014 Dec 18. doi: 10.1161/ATVBAHA.114.304878

PMCID:: PMC4305040

Abstract Article PDF–1.7M

Select item 41964408.

Modeling of Corticosteroid Effects on Hepatic Low-Density Lipoprotein Receptors and Plasma Lipid Dynamics in Rats

Anasuya Hazra, Nancy A. Pyszczynski, Debra C. DuBois, Richard R. Almon, William J. Jusko

Pharm Res. Author manuscript; available in PMC 2014 Oct 14.

Published in final edited form as: Pharm Res. 2008 Apr; 25(4): 769–780. Published online 2007 Aug 3. doi: 10.1007/s11095-007-9371-8

PMCID:: PMC4196440

Abstract Article PDF–2.1M

Select item 39364779.

Apolipoprotein E – Low Density Lipoprotein Receptor Interaction Affects Spatial Memory Retention and Brain ApoE Levels in an Isoform-Dependent Manner

Lance A. Johnson, Reid H.J. Olsen, Louise S. Merkens, Andrea DeBarber, Robert D. Steiner, Patrick M. Sullivan, Nobuyo Maeda, Jacob Raber

Neurobiol Dis. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: Neurobiol Dis. 2014 Apr; 64: 150–162. Published online 2014 Jan 9. doi: 10.1016/j.nbd.2013.12.016

PMCID:: PMC3936477

Abstract Article PDF–3.2M

Select item 375099610.

Interleukin-27 Receptor Limits Atherosclerosis in Ldlr^−/− Mice

Ekaterina K. Koltsova, Gisen Kim, Kathleen M. Lloyd, Christiaan J.M. Saris, von Vietinghoff Sibylle, Mitchell Kronenberg, Klaus Ley

Circ Res. Author manuscript; available in PMC 2013 Aug 23.

Published in final edited form as: Circ Res. 2012 Oct 26; 111(10): 1274–1285. Published online 2012 Aug 27. doi: 10.1161/CIRCRESAHA.112.277525

PMCID:: PMC3750996

Abstract Article PDF–5.7M

Select item 362217711.

SEC24A deficiency lowers plasma cholesterol through reduced PCSK9 secretion

Xiao-Wei Chen, He Wang, Kanika Bajaj, Pengcheng Zhang, Zhuo-Xian Meng, Danjun Ma, Yongsheng Bai, Hui-Hui Liu, Elizabeth Adams, Andrea Baines, Genggeng Yu, Maureen A Sartor, Bin Zhang, Zhengping Yi, Jiandie Lin, Stephen G Young, Randy Schekman, David Ginsburg

eLife. 2013; 2: e00444. Published online 2013 Apr 9. doi: 10.7554/eLife.00444

PMCID:: PMC3622177

Abstract Article PDF–5.3M

Select item 358195412.

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins

Rajesh Ghai, Andrea Bugarcic, Huadong Liu, Suzanne J. Norwood, Sune Skeldal, Elizabeth J. Coulson, Shawn Shun-Cheng Li, Rohan D. Teasdale, Brett M. Collins

Proc Natl Acad Sci U S A. 2013 Feb 19; 110(8): E643–E652. Published online 2013 Feb 4. doi: 10.1073/pnas.1216229110

PMCID:: PMC3581954

Abstract Article PDF–2.3M

Select item 340713113.

Annexin A2 Is a Natural Extrahepatic Inhibitor of the PCSK9-Induced LDL Receptor Degradation

Nabil G. Seidah, Steve Poirier, Maxime Denis, Rex Parker, Bowman Miao, Claudio Mapelli, Annik Prat, Hanny Wassef, Jean Davignon, Katherine A. Hajjar, Gaétan Mayer

PLoS One. 2012; 7(7): e41865. Published online 2012 Jul 27. doi: 10.1371/journal.pone.0041865

PMCID:: PMC3407131

Abstract Article PDF–683K

Select item 334015114.

Low-density Lipoprotein Receptor Represents an Apolipoprotein E-independent Pathway of Aβ Uptake and Degradation by Astrocytes

Jacob M. Basak, Philip B. Verghese, Hyejin Yoon, Jungsu Kim, David M. Holtzman

J Biol Chem. 2012 Apr 20; 287(17): 13959–13971. Published online 2012 Mar 1. doi: 10.1074/jbc.M111.288746

PMCID:: PMC3340151

Abstract Article PDF–2.1M

Select item 326002515.

Chronic Alcohol Consumption Disrupted Cholesterol Homeostasis in Rats: Downregulation of Low Density Lipoprotein Receptor and Enhancement of Cholesterol Biosynthesis Pathway in the Liver

Zhigang Wang, Tong Yao, Zhenyuan Song

Alcohol Clin Exp Res. Author manuscript; available in PMC 2012 Jan 17.

Published in final edited form as: Alcohol Clin Exp Res. 2010 Mar 1; 34(3): 471–478. Published online 2009 Dec 18. doi: 10.1111/j.1530-0277.2009.01111.x

PMCID:: PMC3260025

Abstract Article PDF–1.0M

Select item 324569516.

Mechanistic implications for LDL receptor degradation from the PCSK9/LDLR structure at neutral pH

Paola Lo Surdo, Matthew J Bottomley, Alessandra Calzetta, Ethan C Settembre, Agostino Cirillo, Shilpa Pandit, Yan G Ni, Brian Hubbard, Ayesha Sitlani, Andrea Carfí

EMBO Rep. 2011 Dec; 12(12): 1300–1305. Published online 2011 Nov 11. doi: 10.1038/embor.2011.205