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Select item 89316191.

宫内发育迟缓出生后追赶生长大鼠脂肪组织 LRP6/ β -catenin通路表达变化

Qiuli CAO, Xiaowei LI, Xiuping XUAN, Song HUANG, Xuemei XIE

Zhejiang Da Xue Xue Bao Yi Xue Ban. 2021 Dec; 50(6): 755–761. Chinese. doi: 10.3724/zdxbyxb-2021-0178

PMCID:: PMC8931619

Abstract Article PDF–5.1M

Select item 75215462.

Insulin-receptor substrate 1 protects against injury in endothelial cell models of ox-LDL-induced atherosclerosis by inhibiting ER stress/oxidative stress-mediated apoptosis and activating the Akt/FoxO1 signaling pathway

Juan Liu, Xu Yi, Yuan Tao, Yanjiang Wang, Zhiqiang Xu

Int J Mol Med. 2020 Nov; 46(5): 1671–1682. Published online 2020 Sep 15. doi: 10.3892/ijmm.2020.4728

PMCID:: PMC7521546

Abstract Article PDF–1.2M

Select item 72321283.

Overexpression of mechanical sensitive miR-337-3p alleviates ectopic ossification in rat tendinopathy model via targeting IRS1 and Nox4 of tendon-derived stem cells

Yiyun Geng, Xiaoying Zhao, Jiajia Xu, Xudong Zhang, Guoli Hu, Sai-Chuen Fu, Kerong Dai, Xiaodong Chen, Yung shu-huang Patrick, Xiaoling Zhang

J Mol Cell Biol. 2020 Apr; 12(4): 305–317. Published online 2019 May 8. doi: 10.1093/jmcb/mjz030

PMCID:: PMC7232128

Abstract Article PDF–2.2M

Select item 50643574.

A novel IRS-1-associated protein, DGKζ regulates GLUT4 translocation in 3T3-L1 adipocytes

TingYu Liu, BuChin Yu, Mamoru Kakino, Hitoshi Fujimoto, Yasutoshi Ando, Fumihiko Hakuno, Shin-Ichiro Takahashi

Sci Rep. 2016; 6: 35438. Published online 2016 Oct 14. doi: 10.1038/srep35438

PMCID:: PMC5064357

Abstract Article PDF–1.4M

Select item 49510205.

High Glucose Impairs Insulin Signaling in the Glomerulus: An In Vitro and Ex Vivo Approach

Elias N. Katsoulieris, Garyfalia I. Drossopoulou, Eleni S. Kotsopoulou, Dimitrios V. Vlahakos, Elias A. Lianos, Effie C. Tsilibary

PLoS One. 2016; 11(7): e0158873. Published online 2016 Jul 19. doi: 10.1371/journal.pone.0158873

PMCID:: PMC4951020

Abstract Article PDF–2.6M

Select item 49242106.

Fermented Red Ginseng Potentiates Improvement of Metabolic Dysfunction in Metabolic Syndrome Rat Models

Min Chul Kho, Yun Jung Lee, Ji Hun Park, Hye Yoom Kim, Jung Joo Yoon, You Mee Ahn, Rui Tan, Min Cheol Park, Jeong Dan Cha, Kyung Min Choi, Dae Gill Kang, Ho Sub Lee

Nutrients. 2016 Jun; 8(6): 369. Published online 2016 Jun 16. doi: 10.3390/nu8060369

PMCID:: PMC4924210

Abstract Article PDF–6.8M

Select item 48753457.

MicroRNAs: a new ray of hope for diabetes mellitus

Munish Kumar, Sayantan Nath, Himanshu K. Prasad, G. D. Sharma, Yong Li

Protein Cell. 2012 Oct; 3(10): 726–738. Published online 2012 Oct 11. doi: 10.1007/s13238-012-2055-0

PMCID:: PMC4875345

Abstract Article PDF–3.8M

Select item 48134808.

Insulin Receptor Substrate 1, the Hub Linking Follicle-stimulating Hormone to Phosphatidylinositol 3-Kinase Activation

Nathan C. Law, Mary E. Hunzicker-Dunn

J Biol Chem. 2016 Feb 26; 291(9): 4547–4560. Published online 2015 Dec 23. doi: 10.1074/jbc.M115.698761

PMCID:: PMC4813480

Abstract Article PDF–2.9M

Select item 47692239.

MiR-126 Suppresses the Glucose-Stimulated Proliferation via IRS-2 in INS-1 β Cells

Hong Tao, Meng-meng Wang, Man Zhang, Shao-ping Zhang, Chun-hui Wang, Wen-jun Yuan, Tao Sun, Lan-jie He, Qi-kuan Hu

PLoS One. 2016; 11(2): e0149954. Published online 2016 Feb 26. doi: 10.1371/journal.pone.0149954

PMCID:: PMC4769223

Abstract Article PDF–1.4M

Select item 458732710.

Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth

Joseph Mertz, Haiyan Tan, Vishwajeeth Pagala, Bing Bai, Ping-Chung Chen, Yuxin Li, Ji-Hoon Cho, Timothy Shaw, Xusheng Wang, Junmin Peng

Mol Cell Proteomics. 2015 Jul; 14(7): 1898–1910. Published online 2015 Apr 30. doi: 10.1074/mcp.M114.045898

PMCID:: PMC4587327

Abstract Article PDF–2.6M

Select item 434249511.

Tumor Necrosis Factor (TNF)-α-induced Repression of GKAP42 Protein Levels through cGMP-dependent Kinase (cGK)-Iα Causes Insulin Resistance in 3T3-L1 Adipocytes

Yasutoshi Ando, Yusuke Shinozawa, Yumi Iijima, Bu-Chin Yu, Meri Sone, Yuko Ooi, Yusuke Watanaka, Kazuhiro Chida, Fumihiko Hakuno, Shin-Ichiro Takahashi

J Biol Chem. 2015 Feb 27; 290(9): 5881–5892. Published online 2015 Jan 13. doi: 10.1074/jbc.M114.624759

PMCID:: PMC4342495

Abstract Article PDF–2.0M

Select item 430376412.

Regulation of Insulin Receptor Substrate 1 Pleckstrin Homology Domain by Protein Kinase C: Role of Serine 24 Phosphorylation

Ranmali Nawaratne, Alexander Gray, Christina H. Jørgensen, C. Peter Downes, Kenneth Siddle, Jaswinder K. Sethi

Mol Endocrinol. Author manuscript; available in PMC 2015 Jan 23.

Published in final edited form as: Mol Endocrinol. 2006 Aug; 20(8): 1838–1852. Published online 2006 Mar 30. doi: 10.1210/me.2005-0536

PMCID:: PMC4303764

Abstract Article PDF–1.7M

Select item 420785513.

Serine 307 on insulin receptor substrate 1 is required for SOCS3 and TNF-α signaling in the rMC-1 cell line

Youde Jiang, Subrata K. Biswas, Jena J. Steinle

Mol Vis. 2014; 20: 1463–1470. Published online 2014 Oct 23.

PMCID:: PMC4207855

Abstract Article PDF–1.6M

Select item 410300914.

Loss of Inhibitory IRS-1 Phosphorylation is an Early Event in mTOR-Dependent Endometrial Hyperplasia and Carcinoma

Adrienne S. McCampbell, Heather A. Harris, Judy S. Crabtree, Richard C. Winneker, Cheryl L. Walker, Russell R. Broaddus

Cancer Prev Res (Phila) Author manuscript; available in PMC 2014 Jul 18.

Published in final edited form as: Cancer Prev Res (Phila). 2010 Mar; 3(3): 290–300. Published online 2010 Feb 23. doi: 10.1158/1940-6207.CAPR-09-0199

PMCID:: PMC4103009

Abstract Article PDF–2.0M

Select item 405288915.

Interleukin-1β impairs brain derived neurotrophic factor-induced signal transduction

Liqi Tong, Robert Balazs, Rungtip Soiampornkul, Wipawan Thangnipon, Carl W. Cotman

Neurobiol Aging. Author manuscript; available in PMC 2014 Jun 11.

Published in final edited form as: Neurobiol Aging. 2008 Sep; 29(9): 1380–1393. Published online 2007 Apr 27. doi: 10.1016/j.neurobiolaging.2007.02.027

PMCID:: PMC4052889

Abstract Article PDF–790K

Select item 401102116.

Crosstalk between the p190-B RhoGAP and IGF signaling pathways is required for embryonic mammary bud development

Brandy M Heckman, Geetika Chakravarty, Tracy Vargo-Gogola, Maria Gonzales-Rimbau, Darryl L Hadsell, Adrian V Lee, Jeffrey Settleman, Jeffrey M Rosen

Dev Biol. Author manuscript; available in PMC 2014 May 6.

Published in final edited form as: Dev Biol. 2007 Sep 1; 309(1): 137–149. Published online 2007 Jul 10. doi: 10.1016/j.ydbio.2007.07.002

PMCID:: PMC4011021

Abstract Article PDF–1.7M

Select item 400744117.

Insulin and Metabolic Stress Stimulate Multisite Serine/Threonine Phosphorylation of Insulin Receptor Substrate 1 and Inhibit Tyrosine Phosphorylation

Nancy J. Hançer, Wei Qiu, Christine Cherella, Yedan Li, Kyle D. Copps, Morris F. White

J Biol Chem. 2014 May 2; 289(18): 12467–12484. Published online 2014 Mar 20. doi: 10.1074/jbc.M114.554162

PMCID:: PMC4007441

Abstract Article PDF–7.5M

Select item 387423218.

SH2-B Promotes Insulin Receptor Substrate 1 (IRS1)- and IRS2-mediated Activation of the Phosphatidylinositol 3-Kinase Pathway in Response to Leptin

Chaojun Duan, Minghua Li, Liangyou Rui

J Biol Chem. Author manuscript; available in PMC 2013 Dec 28.

Published in final edited form as: J Biol Chem. 2004 Oct 15; 279(42): 10.1074/jbc.M408495200. Published online 2004 Aug 16. doi: 10.1074/jbc.M408495200

PMCID:: PMC3874232

Abstract Article PDF–801K

Select item 374200119.

mTORC1 inhibition induces pain via IRS-1-dependent feedback activation of ERK

Ohannes K. Melemedjian, Arkady Khoutorsky, Robert E. Sorge, Jin Yan, Marina N. Asiedu, Arely Valdez, Sourav Ghosh, Gregory Dussor, Jeffrey S. Mogil, Nahum Sonenberg, Theodore J. Price

Pain. Author manuscript; available in PMC 2014 Jul 1.

Published in final edited form as: Pain. 2013 Jul; 154(7): 1080–1091. Published online 2013 Mar 15. doi: 10.1016/j.pain.2013.03.021

PMCID:: PMC3742001

Abstract Article PDF–2.1M

Select item 368858720.

Genome-Wide DNA Methylation Analysis Reveals a Potential Mechanism for the Pathogenesis and Development of Uterine Leiomyomas

Ryo Maekawa, Shun Sato, Yoshiaki Yamagata, Hiromi Asada, Isao Tamura, Lifa Lee, Maki Okada, Hiroshi Tamura, Eiichi Takaki, Akira Nakai, Norihiro Sugino

PLoS One. 2013; 8(6): e66632. Published online 2013 Jun 20. doi: 10.1371/journal.pone.0066632