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Items: 1 to 20 of 36

1.
Changes in gut microbiome correlate with intestinal barrier dysfunction and inflammation following a 3-day ethanol exposure in aged mice
Rachel H. McMahan, Holly J. Hulsebus, Kevin M. Najarro, Lauren E. Giesy, Daniel N. Frank, Elizabeth J. Kovacs
Alcohol. Author manuscript; available in PMC 2023 May 30.
Published in final edited form as: Alcohol. 2023 Mar; 107: 136–143. Published online 2022 Sep 21. doi: 10.1016/j.alcohol.2022.08.011
PMCID:
PMC10228642
AbstractArticlePDF–1.0M
2.
Cysteine-Rich LIM-Only Protein 4 (CRP4) Promotes Atherogenesis in the ApoE−/− Mouse Model
Natalie Längst, Julia Adler, Anna Kuret, Andreas Peter, Peter Ruth, Karsten Boldt, Robert Lukowski
Cells. 2022 Apr; 11(8): 1364. Published online 2022 Apr 17. doi: 10.3390/cells11081364
PMCID:
PMC9032522
AbstractArticlePDF–5.4M
3.
Changes to gut amino acid transporters and microbiome associated with increased E/I ratio in Chd8+/− mouse model of ASD-like behavior
You Yu, Bing Zhang, Peifeng Ji, Zhenqiang Zuo, Yongxi Huang, Ning Wang, Chang Liu, Shuang-Jiang Liu, Fangqing Zhao
Nat Commun. 2022; 13: 1151. Published online 2022 Mar 3. doi: 10.1038/s41467-022-28746-2
PMCID:
PMC8894489
AbstractArticlePDF–3.1M
4.
IFN-γ mediates Paneth cell death via suppression of mTOR
Alessandra Araujo, Alexandra Safronova, Elise Burger, Américo López-Yglesias, Shilpi Giri, Ellie T Camanzo, Andrew T Martin, Sergei Grivennikov, Felix Yarovinsky
eLife. 2021; 10: e60478. Published online 2021 Oct 11. doi: 10.7554/eLife.60478
PMCID:
PMC8570691
AbstractArticlePDF–14M
5.
Western Diet Induces Paneth Cell Defects through Microbiome Alterations and Farnesoid X Receptor and Type I Interferon Activation
Ta-Chiang Liu, Justin T. Kern, Umang Jain, Naomi M. Sonnek, Shanshan Xiong, Katherine F. Simpson, Kelli L. VanDussen, Emma S. Winkler, Talin Haritunians, Atika Malique, Qiuhe Lu, Yo Sasaki, Chad Storer, Michael S. Diamond, Richard D. Head, Dermot P.B. McGovern, Thaddeus S. Stappenbeck
Cell Host Microbe. Author manuscript; available in PMC 2022 Jun 9.
Published in final edited form as: Cell Host Microbe. 2021 Jun 9; 29(6): 988–1001.e6. Published online 2021 May 18. doi: 10.1016/j.chom.2021.04.004
PMCID:
PMC8192497
AbstractArticlePDF–1.9M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
The RNA helicase Dhx15 mediates Wnt-induced antimicrobial protein expression in Paneth cells
Yalong Wang, Kaixin He, Baifa Sheng, Xuqiu Lei, Wanyin Tao, Xiaoliang Zhu, Zheng Wei, Rongjie Fu, Anlei Wang, Shengdan Bai, Zhao Zhang, Na Hong, Chao Ye, Ye Tian, Jun Wang, Mingsong Li, Kaiguang Zhang, Lin Li, Hua Yang, Hua-Bing Li, Richard A. Flavell, Shu Zhu
Proc Natl Acad Sci U S A. 2021 Jan 26; 118(4): e2017432118. Published online 2021 Jan 22. doi: 10.1073/pnas.2017432118
Correction in:
Proc Natl Acad Sci U S A. 2021 Aug 10; 118(32): e2111936118.
PMCID:
PMC7848544
AbstractArticlePDF–1.6M
8.
Paneth cell–derived growth factors support tumorigenesis in the small intestine
Qing Chen, Kohei Suzuki, Luis Sifuentes-Dominguez, Naoteru Miyata, Jie Song, Adam Lopez, Petro Starokadomskyy, Purva Gopal, Igor Dozmorov, Shuai Tan, Bujun Ge, Ezra Burstein
Life Sci Alliance. 2021 Mar; 4(3): e202000934. Published online 2020 Dec 28. doi: 10.26508/lsa.202000934
PMCID:
PMC7772774
AbstractArticlePDF–3.1M
9.
LGR5 controls extracellular matrix production by stem cells in the developing intestine
Valeria Fernandez Vallone, Morgane Leprovots, Didac Ribatallada‐Soriano, Romain Gerbier, Anne Lefort, Frédérick Libert, Gilbert Vassart, Marie‐Isabelle Garcia
EMBO Rep. 2020 Jul 3; 21(7): e49224. Published online 2020 May 28. doi: 10.15252/embr.201949224
PMCID:
PMC7332981
AbstractArticlePDF–7.1M
10.
Increased gene copy number of DEFA1/DEFA3 worsens sepsis by inducing endothelial pyroptosis
QiXing Chen, Yang Yang, JinChao Hou, Qiang Shu, YiXuan Yin, WeiTao Fu, Feng Han, TingJun Hou, CongLi Zeng, Elizabeta Nemeth, Rose Linzmeier, Tomas Ganz, XiangMing Fang
Proc Natl Acad Sci U S A. 2019 Feb 19; 116(8): 3161–3170. Published online 2019 Feb 4. doi: 10.1073/pnas.1812947116
Correction in:
Proc Natl Acad Sci U S A. 2022 Jan 25; 119(4): e2121889119.
PMCID:
PMC6386704
AbstractArticlePDF–1.7M
11.
Loss of Paneth cell autophagy causes acute susceptibility to Toxoplasma gondii-mediated inflammation
Elise Burger, Alessandra Araujo, Américo López-Yglesias, Michael W. Rajala, Linda Geng, Beth Levine, Lora V. Hooper, Ezra Burstein, Felix Yarovinsky
Cell Host Microbe. Author manuscript; available in PMC 2019 Feb 14.
Published in final edited form as: Cell Host Microbe. 2018 Feb 14; 23(2): 177–190.e4. Published online 2018 Jan 18. doi: 10.1016/j.chom.2018.01.001
PMCID:
PMC6179445
AbstractArticlePDF–1.1M
12.
Cryptdin-2 predicts intestinal injury during heatstroke in mice
Jingjing Ji, Zhengtao Gu, Hui Li, Lei Su, Zhifeng Liu
Int J Mol Med. 2018 Jan; 41(1): 137–146. Published online 2017 Nov 1. doi: 10.3892/ijmm.2017.3229
PMCID:
PMC5746321
AbstractArticlePDF–1.0M
13.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
14.
Biosynthesis and antimicrobial evaluation of backbone-cyclized alpha-defensins#
Angie E. Garcia, Kenneth P. Tai, Shadakshara S. Puttamadappa, Alexander Shekhtman, Andre J. Ouellette, Julio A. Camarero
Biochemistry. Author manuscript; available in PMC 2012 Dec 6.
Published in final edited form as: Biochemistry. 2011 Dec 6; 50(48): 10508–10519. Published online 2011 Nov 9. doi: 10.1021/bi201430f
PMCID:
PMC3236816
AbstractArticlePDF–1.9M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Lgr4 is required for Paneth cell differentiation and maintenance of intestinal stem cells ex vivo
Roxana C Mustata, Tom Van Loy, Anne Lefort, Frédérick Libert, Sandra Strollo, Gilbert Vassart, Marie-Isabelle Garcia
EMBO Rep. 2011 Jun; 12(6): 558–564. Published online 2011 Apr 21. doi: 10.1038/embor.2011.52
PMCID:
PMC3128273
AbstractArticlePDF–1.5M
17.
Strain-Specific Polymorphisms in Paneth Cell α-Defensins of C57BL/6 Mice and Evidence of Vestigial Myeloid α-Defensin Pseudogenes
Michael T. Shanahan, Hiroki Tanabe, André J. Ouellette
Infect Immun. 2011 Jan; 79(1): 459–473. Published online 2010 Nov 1. doi: 10.1128/IAI.00996-10
PMCID:
PMC3019906
AbstractArticlePDF–4.3M
18.
Elevated Expression of Paneth Cell CRS4C in Ileitis-prone SAMP1/YitFc Mice: REGIONAL DISTRIBUTION, SUBCELLULAR LOCALIZATION, AND MECHANISM OF ACTION
Michael T. Shanahan, Alda Vidrich, Yoshinori Shirafuji, Claire L. Dubois, Agnes Henschen-Edman, Susan J. Hagen, Steven M. Cohn, André J. Ouellette
J Biol Chem. 2010 Mar 5; 285(10): 7493–7504. Published online 2010 Jan 7. doi: 10.1074/jbc.M109.083220
PMCID:
PMC2844197
AbstractArticlePDF–1.9M
19.
Manual annotation and analysis of the defensin gene cluster in the C57BL/6J mouse reference genome
Clara Amid, Linda M Rehaume, Kelly L Brown, James GR Gilbert, Gordon Dougan, Robert EW Hancock, Jennifer L Harrow
BMC Genomics. 2009; 10: 606. Published online 2009 Dec 15. doi: 10.1186/1471-2164-10-606
PMCID:
PMC2807441
AbstractArticlePDF–477K
20.
Electropositive Charge in α-Defensin Bactericidal Activity: Functional Effects of Lys-for-Arg Substitutions Vary with the Peptide Primary Structure
R. Alan Llenado, Colby S. Weeks, Melanie J. Cocco, André J. Ouellette
Infect Immun. 2009 Nov; 77(11): 5035–5043. Published online 2009 Sep 8. doi: 10.1128/IAI.00695-09
PMCID:
PMC2772546
AbstractArticlePDF–1.7M

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