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Items: 1 to 20 of 88

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Endogenous retroviruses shape pluripotency specification in mouse embryos
Sergio de la Rosa, María del Mar Rigual, Pierfrancesco Vargiu, Sagrario Ortega, Nabil Djouder
Sci Adv. 2024 Jan 26; 10(4): eadk9394. Published online 2024 Jan 24. doi: 10.1126/sciadv.adk9394
PMCID:
PMC10807815
AbstractArticlePDF–23M
3.
CARM1 arginine methyltransferase as a therapeutic target for cancer
Margarida Santos, Jee Won Hwang, Mark T. Bedford
J Biol Chem. 2023 Sep; 299(9): 105124. Published online 2023 Aug 1. doi: 10.1016/j.jbc.2023.105124
PMCID:
PMC10474102
AbstractArticlePDF–1.7M
4.
Arginine methylation of PPP1CA by CARM1 regulates glucose metabolism and affects osteogenic differentiation and osteoclastic differentiation
Lu Zhang, Guangjun Jiao, Yunhao You, Xiang Li, Jincheng Liu, Zhenqian Sun, Qinghui Li, Zihan Dai, Jinlong Ma, Hongming Zhou, Gang Li, Chunyang Meng, Yunzhen Chen
Clin Transl Med. 2023 Sep; 13(9): e1369. Published online 2023 Aug 30. doi: 10.1002/ctm2.1369
PMCID:
PMC10468565
AbstractArticlePDF–6.5M
5.
PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ
Yi Zhong, Yilong Wang, Xiaoguang Li, Haojie Qin, Shu Yan, Caijun Rao, Di Fan, Duqiu Liu, Fei Deng, Yanli Miao, Ling Yang, Kai Huang
Diabetes. 2023 Aug; 72(8): 1095–1111. Published online 2023 May 22. doi: 10.2337/db22-1016
PMCID:
PMC10382653
AbstractArticlePDF–42M
6.
Role of Coactivator Associated Arginine Methyltransferase 1 (CARM1) in the Regulation of the Biological Function of 1,25-Dihydroxyvitamin D3
Leila J. Mady, Yan Zhong, Puneet Dhawan, Sylvia Christakos
Cells. 2023 May; 12(10): 1407. Published online 2023 May 17. doi: 10.3390/cells12101407
PMCID:
PMC10216765
AbstractArticlePDF–1.8M
7.
The NFIB/CARM1 partnership is a driver in preclinical models of small cell lung cancer
Guozhen Gao, Simone Hausmann, Natasha M. Flores, Ana Morales Benitez, Jianjun Shen, Xiaojie Yang, Maria D. Person, Sitaram Gayatri, Donghang Cheng, Yue Lu, Bin Liu, Pawel K. Mazur, Mark T. Bedford
Nat Commun. 2023; 14: 363. Published online 2023 Jan 23. doi: 10.1038/s41467-023-35864-y
PMCID:
PMC9870865
AbstractArticlePDF–6.7M
8.
The CARM1 transcriptome and arginine methylproteome mediate skeletal muscle integrative biology
Tiffany L. vanLieshout, Derek W. Stouth, Nicolas G. Hartel, Goutham Vasam, Sean Y. Ng, Erin K. Webb, Irena A. Rebalka, Andrew I. Mikhail, Nicholas A. Graham, Keir J. Menzies, Thomas J. Hawke, Vladimir Ljubicic
Mol Metab. 2022 Oct; 64: 101555. Published online 2022 Jul 21. doi: 10.1016/j.molmet.2022.101555
PMCID:
PMC9379683
AbstractArticlePDF–4.1M
9.
The arginine methyltransferase Carm1 is necessary for heart development
Sophie Jamet, Seungshin Ha, Tzu-Hua Ho, Scott Houghtaling, Andrew Timms, Kai Yu, Alison Paquette, Ali Murat Maga, Nicholas D E Greene, David R Beier
G3 (Bethesda) 2022 Aug; 12(8): jkac155. Published online 2022 Jun 23. doi: 10.1093/g3journal/jkac155
PMCID:
PMC9339313
AbstractArticlePDF–1.7M
10.
The circular RNA circHMGB2 drives immunosuppression and anti-PD-1 resistance in lung adenocarcinomas and squamous cell carcinomas via the miR-181a-5p/CARM1 axis
Ling-Xian Zhang, Jian Gao, Xiang Long, Peng-Fei Zhang, Xin Yang, Shu-Qiang Zhu, Xu Pei, Bai-Quan Qiu, Shi-Wei Chen, Feng Lu, Kun Lin, Jian Jun Xu, Yong-Bing Wu
Mol Cancer. 2022; 21: 110. Published online 2022 May 7. doi: 10.1186/s12943-022-01586-w
PMCID:
PMC9077876
AbstractArticlePDF–16M
11.
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
Keith A. Lawson, Cristovão M. Sousa, Xiaoyu Zhang, Eiru Kim, Rummy Akthar, Joseph J. Caumanns, Yuxi Yao, Nicholas Mikolajewicz, Catherine Ross, Kevin R. Brown, Abdelrahman Abou Zid, Zi Peng Fan, Shirley Hui, Jordan A. Krall, Donald M. Simons, Chloe J. Slater, Victor De Jesus, Lujia Tang, Richa Singh, Joshua E. Goldford, Sarah Martin, Qian Huang, Elizabeth A. Francis, Andrea Habsid, Ryan Climie, David Tieu, Jiarun Wei, Ren Li, Amy Hin Yan Tong, Michael Aregger, Katherine S. Chan, Hong Han, Xiaowei Wang, Patricia Mero, John H. Brumell, Antonio Finelli, Laurie Ailles, Gary Bader, Gromoslaw A. Smolen, Gillian A. Kingsbury, Traver Hart, Charles Kung, Jason Moffat
Nature. Author manuscript; available in PMC 2022 Apr 18.
Published in final edited form as: Nature. 2020 Oct; 586(7827): 120–126. Published online 2020 Sep 23. doi: 10.1038/s41586-020-2746-2
PMCID:
PMC9014559
AbstractArticlePDF–6.6M
12.
Mutations in Hcfc1 and Ronin result in an inborn error of cobalamin metabolism and ribosomopathy
Tiffany Chern, Annita Achilleos, Xuefei Tong, Matthew C. Hill, Alexander B. Saltzman, Lucas C. Reineke, Arindam Chaudhury, Swapan K. Dasgupta, Yushi Redhead, David Watkins, Joel R. Neilson, Perumal Thiagarajan, Jeremy B. A. Green, Anna Malovannaya, James F. Martin, David S. Rosenblatt, Ross A. Poché
Nat Commun. 2022; 13: 134. Published online 2022 Jan 10. doi: 10.1038/s41467-021-27759-7
PMCID:
PMC8748873
AbstractArticlePDF–11M
13.
Endotoxin stabilizes protein arginine methyltransferase 4 (PRMT4) protein triggering death of lung epithelia
Yandong Lai, Xiuying Li, Tiao Li, Toru Nyunoya, Kong Chen, Georgios D. Kitsios, Seyed Mehdi Nouraie, Yingze Zhang, Bryan J. McVerry, Janet S. Lee, Rama K. Mallampalli, Chunbin Zou
Cell Death Dis. 2021 Sep; 12(9): 828. Published online 2021 Sep 3. doi: 10.1038/s41419-021-04115-7
PMCID:
PMC8414963
AbstractArticlePDF–4.0M
14.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
15.
Genetic evidence for partial redundancy between the arginine methyltransferases CARM1 and PRMT6
Donghang Cheng, Guozhen Gao, Alessandra Di Lorenzo, Sandrine Jayne, Michael O. Hottiger, Stephane Richard, Mark T. Bedford
J Biol Chem. 2020 Dec 11; 295(50): 17060–17070. Published online 2020 Oct 2. doi: 10.1074/jbc.RA120.014704
PMCID:
PMC7863876
AbstractArticlePDF–2.4M
16.
Pontin arginine methylation by CARM1 is crucial for epigenetic regulation of autophagy
Young Suk Yu, Hijai R. Shin, Dongha Kim, Seon Ah Baek, Seon Ah Choi, Hyejin Ahn, Amen Shamim, Jeonghwan Kim, Ik Soo Kim, Kyeong Kyu Kim, Kyoung-Jae Won, Sung Hee Baek
Nat Commun. 2020; 11: 6297. Published online 2020 Dec 8. doi: 10.1038/s41467-020-20080-9
PMCID:
PMC7722926
AbstractArticlePDF–4.6M
17.
CARM1 Regulates AMPK Signaling in Skeletal Muscle
Derek W. Stouth, Tiffany L. vanLieshout, Sean Y. Ng, Erin K. Webb, Alexander Manta, Zachary Moll, Vladimir Ljubicic
iScience. 2020 Nov 20; 23(11): 101755. Published online 2020 Nov 2. doi: 10.1016/j.isci.2020.101755
PMCID:
PMC7672286
AbstractArticlePDF–4.7M
18.
Protein arginine methyltransferase expression and activity during myogenesis
Nicole Y. Shen, Sean Y. Ng, Stephen L. Toepp, Vladimir Ljubicic
Biosci Rep. 2018 Feb 28; 38(1): BSR20171533. Prepublished online 2017 Dec 5. Published online 2018 Jan 10. doi: 10.1042/BSR20171533
PMCID:
PMC6435512
AbstractArticlePDF–1.7M
19.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
20.
CARM1 and Paraspeckles Regulate Pre-implantation Mouse Embryo Development
Anna Hupalowska, Agnieszka Jedrusik, Meng Zhu, Mark T. Bedford, David M. Glover, Magdalena Zernicka-Goetz
Cell. 2018 Dec 13; 175(7): 1902–1916.e13. doi: 10.1016/j.cell.2018.11.027
PMCID:
PMC6292842
AbstractArticlePDF–9.4M

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