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Items: 19

1.
Pyruvate dehydrogenase kinase regulatory mechanisms and inhibition in treating diabetes, heart ischemia, and cancer
T. E. Roche, Y. Hiromasa
Cell Mol Life Sci. 2007 Apr; 64(7-8): 830. Published online 2007 Feb 19. doi: 10.1007/s00018-007-6380-z
PMCID:
PMC11136253
AbstractArticlePDF–855K
2.
Structural Analysis of Hippocampal Kinase Signal Transduction
Daniel B. McClatchy, Nam-Kyung Yu, Salvador Martínez-Bartolomé, Reesha Patel, Alexander R. Pelletier, Mathieu Lavalle-Adam, Susan B. Powell, Marissa Roberto, John R. Yates
ACS Chem Neurosci. Author manuscript; available in PMC 2019 Apr 17.
Published in final edited form as: ACS Chem Neurosci. 2018 Dec 19; 9(12): 3072–3085. Published online 2018 Aug 13. doi: 10.1021/acschemneuro.8b00284
PMCID:
PMC6374210
AbstractArticlePDF–1.4M
3.
Pyruvate Dehydrogenase Kinase-mediated Glycolytic Metabolic Shift in the Dorsal Root Ganglion Drives Painful Diabetic Neuropathy
Md Habibur Rahman, Mithilesh Kumar Jha, Jong-Heon Kim, Youngpyo Nam, Maan Gee Lee, Younghoon Go, Robert A. Harris, Dong Ho Park, Hyun Kook, In-Kyu Lee, Kyoungho Suk
J Biol Chem. 2016 Mar 11; 291(11): 6011–6025. Published online 2016 Jan 14. doi: 10.1074/jbc.M115.699215
PMCID:
PMC4786733
AbstractArticlePDF–3.1M
4.
Fasting induces ketoacidosis and hypothermia in PDHK2/PDHK4-double-knockout mice
Nam Ho Jeoung, Yasmeen Rahimi, Pengfei Wu, W. N. Paul Lee, Robert A. Harris
Biochem J. Author manuscript; available in PMC 2015 Feb 10.
Published in final edited form as: Biochem J. 2012 May 1; 443(3): 829–839. doi: 10.1042/BJ20112197
PMCID:
PMC4323161
AbstractArticlePDF–437K
5.
Elucidation of the Interaction Loci of the Human Pyruvate Dehydrogenase Complex E2·E3BP Core with Pyruvate Dehydrogenase Kinase 1 and Kinase 2 by H/D Exchange Mass Spectrometry and Nuclear Magnetic Resonance
Junjie Wang, Sowmini Kumaran, Jieyu Zhou, Natalia S. Nemeria, Hu Tao, Lazaros Kakalis, Yun-Hee Park, Barbara Birkaya, Mulchand S. Patel, Frank Jordan
Biochemistry. 2015 Jan 13; 54(1): 69–82. Published online 2014 Dec 1. doi: 10.1021/bi5013113
PMCID:
PMC4295793
AbstractArticlePDF–5.1M
6.
Inactivation of Pyruvate Dehydrogenase Kinase 2 by Mitochondrial Reactive Oxygen Species
Thomas R. Hurd, Yvonne Collins, Irina Abakumova, Edward T. Chouchani, Bartlomiej Baranowski, Ian M. Fearnley, Tracy A. Prime, Michael P. Murphy, Andrew M. James
J Biol Chem. 2012 Oct 12; 287(42): 35153–35160. Published online 2012 Aug 21. doi: 10.1074/jbc.M112.400002
PMCID:
PMC3471752
AbstractArticlePDF–1.1M
7.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
8.
Chronic CSE Treatment Induces the Growth of Normal Oral Keratinocytes via PDK2 Upregulation, Increased Glycolysis and HIF1α Stabilization
Wenyue Sun, Steven S. Chang, Yumei Fu, Yan Liu, Joseph A. Califano
PLoS One. 2011; 6(1): e16207. Published online 2011 Jan 19. doi: 10.1371/journal.pone.0016207
PMCID:
PMC3023770
AbstractArticlePDF–526K
9.
Pivotal Role of the C-terminal DW-motif in Mediating Inhibition of Pyruvate Dehydrogenase Kinase 2 by Dichloroacetate
Jun Li, Masato Kato, David T. Chuang
J Biol Chem. 2009 Dec 4; 284(49): 34458–34467. Published online 2009 Oct 15. doi: 10.1074/jbc.M109.065557
PMCID:
PMC2797213
AbstractArticlePDF–2.4M
10.
A mitochondrial protein compendium elucidates complex I disease biology
David J. Pagliarini, Sarah E. Calvo, Betty Chang, Sunil A. Sheth, Scott B. Vafai, Shao-En Ong, Geoffrey A. Walford, Canny Sugiana, Avihu Boneh, William K. Chen, David E. Hill, Marc Vidal, James G. Evans, David R. Thorburn, Steven A. Carr, Vamsi K. Mootha
Cell. Author manuscript; available in PMC 2009 Nov 18.
Published in final edited form as: Cell. 2008 Jul 11; 134(1): 112–123. doi: 10.1016/j.cell.2008.06.016
PMCID:
PMC2778844
AbstractArticlePDF–1.2M
11.
Allosteric Coupling in Pyruvate Dehydrogenase Kinase 2
Alla Klyuyeva, Alina Tuganova, Kirill M. Popov
Biochemistry. Author manuscript; available in PMC 2008 Oct 16.
Published in final edited form as: Biochemistry. 2008 Aug 12; 47(32): 8358–8366. Published online 2008 Jul 16. doi: 10.1021/bi800631h
PMCID:
PMC2568900
AbstractArticlePDF–2.0M
12.
The Carboxy-Terminal Tail of Pyruvate Dehydrogenase Kinase 2 Is Required for the Kinase Activity
Alla Klyuyeva, Alina Tuganova, Kirill M. Popov
Biochemistry. Author manuscript; available in PMC 2007 Dec 13.
Published in final edited form as: Biochemistry. 2005 Oct 18; 44(41): 13573–13582. doi: 10.1021/bi0505868
PMCID:
PMC2136410
AbstractArticlePDF–1.4M
13.
Amino acid residues responsible for the recognition of dichloroacetate by pyruvate dehydrogenase kinase 2
Alla Klyuyeva, Alina Tuganova, Kirill M. Popov
FEBS Lett. Author manuscript; available in PMC 2007 Sep 7.
Published in final edited form as: FEBS Lett. 2007 Jun 26; 581(16): 2988–2992. Published online 2007 May 29. doi: 10.1016/j.febslet.2007.05.052
PMCID:
PMC1950259
AbstractArticlePDF–449K
14.
Investigation of potential mechanisms regulating protein expression of hepatic pyruvate dehydrogenase kinase isoforms 2 and 4 by fatty acids and thyroid hormone.
Mark J Holness, Karen Bulmer, Nicholas D Smith, Mary C Sugden
Biochem J. 2003 Feb 1; 369(Pt 3): 687–695. doi: 10.1042/BJ20021509
PMCID:
PMC1223128
SummaryPDF–249K
15.
Regulation of pyruvate dehydrogenase activity through phosphorylation at multiple sites.
E Kolobova, A Tuganova, I Boulatnikov, K M Popov
Biochem J. 2001 Aug 15; 358(Pt 1): 69–77. doi: 10.1042/0264-6021:3580069
PMCID:
PMC1222033
SummaryPDF–195K
16.
Fibre-type specific modification of the activity and regulation of skeletal muscle pyruvate dehydrogenase kinase (PDK) by prolonged starvation and refeeding is associated with targeted regulation of PDK isoenzyme 4 expression.
M C Sugden, A Kraus, R A Harris, M J Holness
Biochem J. 2000 Mar 15; 346(Pt 3): 651–657.
PMCID:
PMC1220897
SummaryPDF–177K
17.
Evidence for existence of tissue-specific regulation of the mammalian pyruvate dehydrogenase complex.
M M Bowker-Kinley, W I Davis, P Wu, R A Harris, K M Popov
Biochem J. 1998 Jan 1; 329(Pt 1): 191–196. doi: 10.1042/bj3290191
PMCID:
PMC1219031
SummaryPDF–219K
18.
The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)
Genome Res. 2004 Oct; 14(10b): 2121–2127. doi: 10.1101/gr.2596504
Correction in:
Genome Res. 2006 Jun; 16(6): 804.
PMCID:
PMC528928
AbstractArticlePDF–140K
19.
Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences
Mammalian Gene Collection (MGC) Program Team
Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899
PMCID:
PMC139241
AbstractArticlePDF–118K

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