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Select item 112890971.

P300 regulates histone crotonylation and preimplantation embryo development

Di Gao, Chao Li, Shao-Yuan Liu, Teng-Teng Xu, Xiao-Ting Lin, Yong-Peng Tan, Fu-Min Gao, Li-Tao Yi, Jian V. Zhang, Jun-Yu Ma, Tie-Gang Meng, William S. B. Yeung, Kui Liu, Xiang-Hong Ou, Rui-Bao Su, Qing-Yuan Sun

Nat Commun. 2024; 15: 6418. Published online 2024 Jul 30. doi: 10.1038/s41467-024-50731-0

PMCID:: PMC11289097

Abstract Article PDF–6.7M

Select item 111052182.

A critical role for miR-142 in alveolar epithelial lineage formation in mouse lung development

Amit Shrestha, Gianni Carraro, Nicolas Nottet, Ana Ivonne Vazquez-Armendariz, Susanne Herold, Julio Cordero, Indrabahadur Singh, Jochen Wilhelm, Guillermo Barreto, Rory Morty, Elie El Agha, Bernard Mari, Chengshui Chen, Jin-San Zhang, Cho-Ming Chao, Saverio Bellusci

Cell Mol Life Sci. 2019 Jul; 76(14): 2817–2832. Published online 2019 Mar 18. doi: 10.1007/s00018-019-03067-8

PMCID:: PMC11105218

Abstract Article PDF–20M

Select item 105803413.

Medial prefrontal cortical PPM1F alters depression‐related behaviors by modifying p300 activity via the AMPK signaling pathway

Jing Liu, Fantao Meng, Wentao Wang, Min Wu, Yu Zhang, Minghu Cui, Changyun Qiu, Fengai Hu, Di Zhao, Dan Wang, Cuilan Liu, Dunjiang Liu, Zhicheng Xu, Yameng Wang, Wei Li, Chen Li

CNS Neurosci Ther. 2023 Nov; 29(11): 3624–3643. Published online 2023 Jun 12. doi: 10.1111/cns.14293

PMCID:: PMC10580341

Abstract Article PDF–14M

Select item 104742924.

The deubiquitinase UCHL3 mediates p300-dependent chemokine signaling in alveolar type II cells to promote pulmonary fibrosis

Soo Yeon Lee, Soo-Yeon Park, Seung-Hyun Lee, Hyunsik Kim, Jae-Hwan Kwon, Jung-Yoon Yoo, Kyunggon Kim, Moo Suk Park, Chun Geun Lee, Jack A. Elias, Myung Hyun Sohn, Hyo Sup Shim, Ho-Geun Yoon

Exp Mol Med. 2023 Aug; 55(8): 1795–1805. Published online 2023 Aug 1. doi: 10.1038/s12276-023-01066-1

PMCID:: PMC10474292

Abstract Article PDF–3.4M

Select item 103242785.

USP24-dependent stabilization of Runx2 recruits a p300/NCOA3 complex to transactivate ADAMTS genes and promote degeneration of intervertebral disc in chronic inflammation mice

Xingguo Li, Jun Zhang, Bing Wang, Chao Chen, Enyu Zhang, Zhengpin Lv, Qicong He, Yaoquan Hu, Xuenan Wang, Fan Zhang

Biol Direct. 2023; 18: 37. Published online 2023 Jul 6. doi: 10.1186/s13062-023-00395-5

PMCID:: PMC10324278

Abstract Article PDF–2.7M

Select item 102316456.

Dynamic changes in P300 enhancers and enhancer-promoter contacts control mouse cardiomyocyte maturation

Pingzhu Zhou, Nathan J. VanDusen, Yanchun Zhang, Yangpo Cao, Isha Sethi, Rong Hu, Shuo Zhang, Guangyu Wang, Lincai Ye, Neil Mazumdar, Jian Chen, Xiaoran Zhang, Yuxuan Guo, Bin Li, Qing Ma, Julianna Y. Lee, Weiliang Gu, Guo-Cheng Yuan, Bing Ren, Kaifu Chen, William T. Pu

Dev Cell. Author manuscript; available in PMC 2024 May 22.

Published in final edited form as: Dev Cell. 2023 May 22; 58(10): 898–914.e7. Published online 2023 Apr 17. doi: 10.1016/j.devcel.2023.03.020

PMCID:: PMC10231645

Abstract Article PDF–3.9M

Select item 96689937.

CBP-HSF2 structural and functional interplay in Rubinstein-Taybi neurodevelopmental disorder

Aurélie de Thonel, Johanna K. Ahlskog, Kevin Daupin, Véronique Dubreuil, Jérémy Berthelet, Carole Chaput, Geoffrey Pires, Camille Leonetti, Ryma Abane, Lluís Cordón Barris, Isabelle Leray, Anna L. Aalto, Sarah Naceri, Marine Cordonnier, Carène Benasolo, Matthieu Sanial, Agathe Duchateau, Anniina Vihervaara, Mikael C. Puustinen, Federico Miozzo, Patricia Fergelot, Élise Lebigot, Alain Verloes, Pierre Gressens, Didier Lacombe, Jessica Gobbo, Carmen Garrido, Sandy D. Westerheide, Laurent David, Michel Petitjean, Olivier Taboureau, Fernando Rodrigues-Lima, Sandrine Passemard, Délara Sabéran-Djoneidi, Laurent Nguyen, Madeline Lancaster, Lea Sistonen, Valérie Mezger

Nat Commun. 2022; 13: 7002. Published online 2022 Nov 16. doi: 10.1038/s41467-022-34476-2

Correction in:: Nat Commun. 2023; 14: 6067.

PMCID:: PMC9668993

Abstract Article PDF–9.1M

Select item 96176198.

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain

Michal Lipinski, Sergio Niñerola, Miguel Fuentes-Ramos, Luis M. Valor, Beatriz del Blanco, Jose P. López-Atalaya, Angel Barco

J Neurosci. 2022 Oct 19; 42(42): 7984–8001. doi: 10.1523/JNEUROSCI.0970-22.2022

PMCID:: PMC9617619

Abstract Article PDF–6.0M

Select item 95612629.

Long noncoding RNA lncMREF promotes myogenic differentiation and muscle regeneration by interacting with the Smarca5/p300 complex

Wei Lv, Wei Jiang, Hongmei Luo, Qian Tong, Xiaoyu Niu, Xiao Liu, Yang Miao, Jingnan Wang, Yiwen Guo, Jianan Li, Xizhen Zhan, Yunqing Hou, Yaxin Peng, Jian Wang, Shuhong Zhao, Zaiyan Xu, Bo Zuo

Nucleic Acids Res. 2022 Oct 14; 50(18): 10733–10755. Published online 2022 Oct 6. doi: 10.1093/nar/gkac854

PMCID:: PMC9561262

Abstract Article PDF–9.6M

Select item 951247910.

Inhibition of CBP/β‐catenin signaling ameliorated fibrosis in cholestatic liver disease

Masamichi Kimura, Koji Nishikawa, Yosuke Osawa, Jun Imamura, Kenzaburo Yamaji, Kenichi Harada, Hiroshi Yatsuhashi, Kazumoto Murata, Kouichi Miura, Atsushi Tanaka, Tatsuya Kanto, Michinori Kohara, Terumi Kamisawa, Kiminori Kimura

Hepatol Commun. 2022 Oct; 6(10): 2732–2747. Published online 2022 Jul 20. doi: 10.1002/hep4.2043

PMCID:: PMC9512479

Abstract Article PDF–19M

Select item 941474111.

ZNF384 Fusion Oncoproteins Drive Lineage Aberrancy in Acute Leukemia

Kirsten M. Dickerson, Chunxu Qu, Qingsong Gao, Ilaria Iacobucci, Zhaohui Gu, Hiroki Yoshihara, Emily A. Backhaus, Yunchao Chang, Laura J. Janke, Beisi Xu, Gang Wu, Evangelia K. Papachristou, Clive S. D'Santos, Kathryn G. Roberts, Charles G. Mullighan

Blood Cancer Discov. 2022 May 5; 3(3): 240–263. Published online 2022 Mar 4. doi: 10.1158/2643-3230.BCD-21-0163

PMCID:: PMC9414741

Abstract Article PDF–9.5M

Select item 884939412.

KIX domain determines a selective tumor-promoting role for EP300 and its vulnerability in small cell lung cancer

Kee-Beom Kim, Ashish Kabra, Dong-Wook Kim, Yongming Xue, Yuanjian Huang, Pei-Chi Hou, Yunpeng Zhou, Leilani J. Miranda, Jae-Il Park, Xiaobing Shi, Timothy P. Bender, John H. Bushweller, Kwon-Sik Park

Sci Adv. 2022 Feb; 8(7): eabl4618. Published online 2022 Feb 16. doi: 10.1126/sciadv.abl4618

PMCID:: PMC8849394

Abstract Article PDF–3.8M

Select item 880044013.

Acetylation of Abelson interactor 1 at K416 regulates actin cytoskeleton and smooth muscle contraction

Yinna Wang, Guoning Liao, Ruping Wang, Dale D. Tang

FASEB J. 2021 Sep; 35(9): e21811. Published online 2021 Aug 9. doi: 10.1096/fj.202100415R

PMCID:: PMC8800440

Abstract Article PDF–1.2M

Select item 876505014.

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes

Vitor F. Martins, Samuel A. LaBarge, Alexandra Stanley, Kristoffer Svensson, Chao-Wei Hung, Omer Keinan, Theodore P. Ciaraldi, Dion Banoian, Ji E. Park, Christina Ha, Byron Hetrick, Gretchen A. Meyer, Andrew Philp, Larry L. David, Robert R. Henry, Joseph E. Aslan, Alan R. Saltiel, Carrie. E. McCurdy, Simon Schenk

JCI Insight. 2022 Jan 11; 7(1): e141344. Published online 2022 Jan 11. doi: 10.1172/jci.insight.141344

PMCID:: PMC8765050

Abstract Article PDF–6.0M

Select item 860478415.

NRF1 Association with AUTS2-Polycomb Mediates Specific Gene Activation in the Brain

Sanxiong Liu, Kimberly A. Aldinger, Chi Vicky Cheng, Takae Kiyama, Mitali Dave, Hanna K. McNamara, Wukui Zhao, James M. Stafford, Nicolas Descostes, Pedro Lee, Stefano G. Caraffi, Ivan Ivanovski, Edoardo Errichiello, Christiane Zweier, Orsetta Zuffardi, Michael Schneider, Antigone S. Papavasiliou, M. Scott Perry, Jennifer Humberson, Megan T. Cho, Astrid Weber, Andrew Swale, Tudor C. Badea, Chai-An Mao, Livia Garavelli, William B. Dobyns, Danny Reinberg

Mol Cell. Author manuscript; available in PMC 2022 Nov 18.

Published in final edited form as: Mol Cell. 2021 Nov 18; 81(22): 4663–4676.e8. Published online 2021 Oct 11. doi: 10.1016/j.molcel.2021.09.020

Correction in:: Mol Cell. 2021 Nov 18; 81(22): 4757.

PMCID:: PMC8604784

Abstract Article PDF–2.8M

Select item 852564016.

p300 suppresses the transition of myelodysplastic syndromes to acute myeloid leukemia

Na Man, Gloria Mas, Daniel L. Karl, Jun Sun, Fan Liu, Qin Yang, Miguel Torres-Martin, Hidehiro Itonaga, Concepcion Martinez, Shi Chen, Ye Xu, Stephanie Duffort, Pierre-Jacques Hamard, Chuan Chen, Beth E. Zucconi, Luisa Cimmino, Feng-Chun Yang, Mingjiang Xu, Philip A. Cole, Maria E. Figueroa, Stephen D. Nimer

JCI Insight. 2021 Oct 8; 6(19): e138478. Published online 2021 Oct 8. doi: 10.1172/jci.insight.138478