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Items: 1 to 20 of 75

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Polarity protein AF6 functions as a modulator of necroptosis by regulating ubiquitination of RIPK1 in liver diseases
Wang Xinyu, Wen Qian, Wu Yanjun, Kong Jingwen, Xu Keying, Jiao Jiazheng, Zhang Haibing, Wang Kai, Xu Xiao, Zhan Lixing
Cell Death Dis. 2023 Oct; 14(10): 673. Published online 2023 Oct 12. doi: 10.1038/s41419-023-06170-8
PMCID:
PMC10570300
AbstractArticlePDF–4.2M
3.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
4.
s-Afadin binds to MAGUIN/Cnksr2 and regulates the localization of the AMPA receptor and glutamatergic synaptic response in hippocampal neurons
Tomohiko Maruo, Kiyohito Mizutani, Muneaki Miyata, Toshihiko Kuriu, Shotaro Sakakibara, Hatena Takahashi, Daichi Kida, Kouki Maesaka, Tsukiko Sugaya, Ayuko Sakane, Takuya Sasaki, Yoshimi Takai, Kenji Mandai
J Biol Chem. 2023 Apr; 299(4): 103040. Published online 2023 Feb 18. doi: 10.1016/j.jbc.2023.103040
PMCID:
PMC10040811
AbstractArticlePDF–1.7M
5.
RGS12 polarizes the GPSM2-GNAI complex to organize and elongate stereocilia in sensory hair cells
Anil Akturk, Matthew Day, Basile Tarchini
Sci Adv. 2022 Oct; 8(42): eabq2826. Published online 2022 Oct 19. doi: 10.1126/sciadv.abq2826
PMCID:
PMC9581478
AbstractArticlePDF–4.3M
6.
ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis
Christophe Royer, Elizabeth Sandham, Elizabeth Slee, Falk Schneider, Christoffer B. Lagerholm, Jonathan Godwin, Nisha Veits, Holly Hathrell, Felix Zhou, Karolis Leonavicius, Jemma Garratt, Tanaya Narendra, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Marco Fritzsche, Xin Lu, Shankar Srinivas
Nat Commun. 2022; 13: 941. Published online 2022 Feb 17. doi: 10.1038/s41467-022-28590-4
PMCID:
PMC8854694
AbstractArticlePDF–15M
7.
Cold-induction of afadin in brown fat supports its thermogenic capacity
Morten Lundh, Ali Altıntaş, Marco Tozzi, Odile Fabre, Tao Ma, Farnaz Shamsi, Zachary Gerhart-Hines, Romain Barrès, Yu-Hua Tseng, Brice Emanuelli
Sci Rep. 2021; 11: 9794. Published online 2021 May 7. doi: 10.1038/s41598-021-89207-2
PMCID:
PMC8105362
AbstractArticlePDF–6.6M
8.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
9.
BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)
Kou Motani, Hidetaka Kosako
J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323
PMCID:
PMC7415991
AbstractArticlePDF–2.0M
10.
Disruption of the nectin-afadin complex recapitulates features of the human cleft lip/palate syndrome CLPED1
Kendall J. Lough, Danielle C. Spitzer, Abby J. Bergman, Jessica J. Wu, Kevin M. Byrd, Scott E. Williams
Development. 2020 Nov 1; 147(21): dev189241. Published online 2020 Jul 13. doi: 10.1242/dev.189241
PMCID:
PMC7375477
AbstractArticle
11.
mTOR and S6K1 drive polycystic kidney by the control of Afadin-dependent oriented cell division
Martina Bonucci, Nicolas Kuperwasser, Serena Barbe, Vonda Koka, Delphine de Villeneuve, Chi Zhang, Nishit Srivastava, Xiaoying Jia, Matthew P. Stokes, Frank Bienaimé, Virginie Verkarre, Jean Baptiste Lopez, Fanny Jaulin, Marco Pontoglio, Fabiola Terzi, Benedicte Delaval, Matthieu Piel, Mario Pende
Nat Commun. 2020; 11: 3200. Published online 2020 Jun 24. doi: 10.1038/s41467-020-16978-z
PMCID:
PMC7314806
AbstractArticlePDF–6.6M
12.
Afadin regulates actomyosin organization through αE-catenin at adherens junctions
Shotaro Sakakibara, Kiyohito Mizutani, Ayumu Sugiura, Ayuko Sakane, Takuya Sasaki, Shigenobu Yonemura, Yoshimi Takai
J Cell Biol. 2020 May 4; 219(5): e201907079. Published online 2020 Mar 30. doi: 10.1083/jcb.201907079
PMCID:
PMC7199863
AbstractArticlePDF–5.5M
13.
Telophase correction refines division orientation in stratified epithelia
Kendall J Lough, Kevin M Byrd, Carlos P Descovich, Danielle C Spitzer, Abby J Bergman, Gerard MJ Beaudoin, III, Louis F Reichardt, Scott E Williams
eLife. 2019; 8: e49249. Published online 2019 Dec 13. doi: 10.7554/eLife.49249
PMCID:
PMC6959978
AbstractArticlePDF–5.4M
14.
Function of Atypical Protein Kinase C λ in Differentiating Photoreceptors Is Required for Proper Lamination of Mouse Retina
Chieko Koike, Akihiro Nishida, Kazunori Akimoto, Masa-aki Nakaya, Tetsuo Noda, Shigeo Ohno, Takahisa Furukawa
J Neurosci. 2005 Nov 2; 25(44): 10290–10298. doi: 10.1523/JNEUROSCI.3657-05.2005
PMCID:
PMC6725782
AbstractArticlePDF–529K
15.
Afadin is a scaffold protein repressing insulin action via HDAC6 in adipose tissue
Morten Lundh, Patricia SS Petersen, Marie S Isidor, Dolly NM Kazoka‐Sørensen, Kaja Plucińska, Farnaz Shamsi, Cathrine Ørskov, Marco Tozzi, Erin L Brown, Emil Andersen, Tao Ma, Ulrich Müller, Romain Barrès, Viggo B Kristiansen, Zachary Gerhart‐Hines, Yu‐Hua Tseng, Brice Emanuelli
EMBO Rep. 2019 Aug; 20(8): e48216. Published online 2019 Jul 2. doi: 10.15252/embr.201948216
PMCID:
PMC6680131
AbstractArticlePDF–2.6M
16.
CADHERIN COMBINATIONS RECRUIT DENDRITES OF DISTINCT RETINAL NEURONS TO A SHARED INTERNEURONAL SCAFFOLD
Xin Duan, Arjun Krishnaswamy, Mallory A. Laboulaye, Jinyue Liu, Yi-Rong Peng, Masahito Yamagata, Kenichi Toma, Joshua R. Sanes
Neuron. Author manuscript; available in PMC 2019 Sep 19.
Published in final edited form as: Neuron. 2018 Sep 19; 99(6): 1145–1154.e6. Published online 2018 Sep 6. doi: 10.1016/j.neuron.2018.08.019
PMCID:
PMC6284407
AbstractArticlePDF–2.2M
17.
Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells
Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch
Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262
PMCID:
PMC6244183
AbstractArticlePDF–753K
18.
Tbr1 instructs laminar patterning of retinal ganglion cell dendrites
Jinyue Liu, Jasmine D. S. Reggiani, Mallory A. Laboulaye, Shristi Pandey, Bin Chen, John L. R. Rubenstein, Arjun Krishnaswamy, Joshua R. Sanes
Nat Neurosci. Author manuscript; available in PMC 2018 Oct 9.
Published in final edited form as: Nat Neurosci. 2018 May; 21(5): 659–670. Published online 2018 Apr 9. doi: 10.1038/s41593-018-0127-z
PMCID:
PMC5920715
AbstractArticlePDF–3.9M
19.
A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies
David K. Breslow, Sascha Hoogendoorn, Adam R. Kopp, David W. Morgens, Brandon K. Vu, Margaret C. Kennedy, Kyuho Han, Amy Li, Gaelen T. Hess, Michael C. Bassik, James K. Chen, Maxence V. Nachury
Nat Genet. Author manuscript; available in PMC 2018 Aug 19.
Published in final edited form as: Nat Genet. 2018 Mar; 50(3): 460–471. Published online 2018 Feb 19. doi: 10.1038/s41588-018-0054-7
PMCID:
PMC5862771
AbstractArticlePDF–2.5M
20.
Afadin and RhoA control pancreatic endocrine mass via lumen morphogenesis
D. Berfin Azizoglu, Caitlin Braitsch, Denise K. Marciano, Ondine Cleaver
Genes Dev. 2017 Dec 1; 31(23-24): 2376–2390. doi: 10.1101/gad.307637.117
PMCID:
PMC5795784
AbstractArticlePDF–26M

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