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Items: 1 to 20 of 271

1.
Transcription factor KROX20 marks epithelial stem cell ancestors for hair follicle formation
Elnaz Ghotbi, Edem Tchegnon, Zhiguo Chen, Stephen Li, Tracey Shipman, Yong Wang, Jenny Raman, Yumeng Zhang, Renee M. McKay, Chung-Ping Liao, Lu Q. Le
J Clin Invest. 2024 Dec 2; 134(23): e180160. Published online 2024 Oct 3. doi: 10.1172/JCI180160
PMCID:
PMC11601947
AbstractArticlePDF–26M
2.
Transcription factor EGR2 alleviates autoimmune uveitis via activation of GDF15 to modulate the retinal microglial phenotype
Wanqian Li, Siyuan He, Jun Tan, Na Li, Chenyang Zhao, Xiaotang Wang, Zhi Zhang, Jiangyi Liu, Jiaxing Huang, Xingran Li, Qian Zhou, Ke Hu, Peizeng Yang, Shengping Hou
Proc Natl Acad Sci U S A. 2024 Sep 24; 121(39): e2316161121. Published online 2024 Sep 19. doi: 10.1073/pnas.2316161121
PMCID:
PMC11441539
AbstractArticlePDF–11M
3.
EGR2 is an epigenomic regulator of phagocytosis and antifungal immunity in alveolar macrophages
Zsuzsanna Kolostyak, Dora Bojcsuk, Viktoria Baksa, Zsuzsa Mathene Szigeti, Krisztian Bene, Zsolt Czimmerer, Pal Boto, Lina Fadel, Szilard Poliska, Laszlo Halasz, Petros Tzerpos, Wilhelm K. Berger, Andres Villabona-Rueda, Zsofia Varga, Tunde Kovacs, Andreas Patsalos, Attila Pap, Gyorgy Vamosi, Peter Bai, Balazs Dezso, Matthew Spite, Franco R. D’Alessio, Istvan Szatmari, Laszlo Nagy
JCI Insight. 2024 Sep 10; 9(17): e164009. Published online 2024 Sep 10. doi: 10.1172/jci.insight.164009
PMCID:
PMC11385099
AbstractArticlePDF–4.6M
4.
Motor innervation directs the correct development of the mouse sympathetic nervous system
Alek G. Erickson, Alessia Motta, Maria Eleni Kastriti, Steven Edwards, Fanny Coulpier, Emy Théoulle, Aliia Murtazina, Irina Poverennaya, Daniel Wies, Jeremy Ganofsky, Giovanni Canu, Francois Lallemend, Piotr Topilko, Saida Hadjab, Kaj Fried, Christiana Ruhrberg, Quenten Schwarz, Valerie Castellani, Dario Bonanomi, Igor Adameyko
Nat Commun. 2024; 15: 7065. Published online 2024 Aug 16. doi: 10.1038/s41467-024-51290-0
PMCID:
PMC11329663
AbstractArticlePDF–7.7M
5.
Egr2 drives the differentiation of Ly6Chi monocytes into fibrosis-promoting macrophages in metabolic dysfunction-associated steatohepatitis in mice
Ayaka Iwata, Juri Maruyama, Shibata Natsuki, Akira Nishiyama, Tomohiko Tamura, Minoru Tanaka, Shigeyuki Shichino, Takao Seki, Toshihiko Komai, Tomohisa Okamura, Keishi Fujio, Masato Tanaka, Kenichi Asano
Commun Biol. 2024; 7: 681. Published online 2024 Jun 3. doi: 10.1038/s42003-024-06357-5
PMCID:
PMC11148031
AbstractArticlePDF–3.7M
6.
Deletion of TECRL promotes skeletal muscle repair by up-regulating EGR2
Sha Geng, Song-Bai Liu, Wei He, Xiangbin Pan, Yi Sun, Ting Xue, Shiyuan Han, Jing Lou, Ying Chang, Jiqing Zheng, Xinghong Shi, Yangxin Li, Yao-Hua Song
Proc Natl Acad Sci U S A. 2024 May 21; 121(21): e2317495121. Published online 2024 May 16. doi: 10.1073/pnas.2317495121
PMCID:
PMC11126978
AbstractArticlePDF–3.8M
7.
Docking protein 6 (DOK6) selectively docks the neurotrophic signaling transduction to restrain peripheral neuropathy
Yan Guo, Pan Xiang, Xiaojiao Sun, Wei Liu, Jiafeng Zhou, Bin Yin, Lin Hou, Boqin Qiang, Huiliang Li, Pengcheng Shu, Xiaozhong Peng
Signal Transduct Target Ther. 2024; 9: 32. Published online 2024 Feb 14. doi: 10.1038/s41392-024-01742-2
PMCID:
PMC10864363
AbstractArticlePDF–9.9M
8.
Neural tube-associated boundary caps are a major source of mural cells in the skin
Gaspard Gerschenfeld, Fanny Coulpier, Aurélie Gresset, Pernelle Pulh, Bastien Job, Thomas Topilko, Julie Siegenthaler, Maria Eleni Kastriti, Isabelle Brunet, Patrick Charnay, Piotr Topilko
eLife. 2023; 12: e69413. Published online 2023 Dec 14. doi: 10.7554/eLife.69413
PMCID:
PMC10786459
AbstractArticlePDF–11M
9.
Egr2 Deletion in Autoimmune-Prone C57BL6/lpr Mice Suppresses the Expression of Methylation-Sensitive Dlk1-Dio3 Cluster MicroRNAs
Zhuang Wang, Bettina Heid, Jianlin He, Hehuang Xie, Christopher M. Reilly, Rujuan Dai, S. Ansar Ahmed
Immunohorizons. 2023 Dec; 7(12): 898–907. Published online 2023 Dec 28. doi: 10.4049/immunohorizons.2300111
PMCID:
PMC10759154
AbstractArticlePDF–1.2M
10.
The transcription factor EGR2 controls homing and pathogenicity of TH17 cells in the central nervous system
Yuanyuan Gao, Yan Wang, Daniel Chauss, Alejandro V. Villarino, Verena M. Link, Hiroyuki Nagashima, Camille A. Spinner, Vishal N. Koparde, Nicolas Bouladoux, Michael S. Abers, Timothy J. Break, Laura B. Chopp, Jung-Hyun Park, Jinfang Zhu, David L. Wiest, Warren J. Leonard, Michail S. Lionakis, John J. O’Shea, Behdad Afzali, Yasmine Belkaid, Vanja Lazarevic
Nat Immunol. Author manuscript; available in PMC 2023 Sep 14.
Published in final edited form as: Nat Immunol. 2023 Aug; 24(8): 1331–1344. Published online 2023 Jul 13. doi: 10.1038/s41590-023-01553-7
PMCID:
PMC10500342
AbstractArticlePDF–2.6M
11.
The transcriptional control of the VEGFA-VEGFR1 (FLT1) axis in alternatively polarized murine and human macrophages
Apolka Domokos, Zsofia Varga, Karoly Jambrovics, Noemí Caballero-Sánchez, Eniko Szabo, Gergely Nagy, Beata Scholtz, Laszlo Halasz, Eszter Varadi, Krisztian P. Bene, Anett Mazlo, Attila Bacsi, Viktoria Jeney, Gabor J. Szebeni, Laszlo Nagy, Zsolt Czimmerer
Front Immunol. 2023; 14: 1168635. Published online 2023 May 4. doi: 10.3389/fimmu.2023.1168635
PMCID:
PMC10192733
AbstractArticlePDF–5.8M
12.
Egr2 and 3 maintain anti-tumour responses of exhausted tumour infiltrating CD8 + T cells
Alistair L. J. Symonds, Tizong Miao, Zabreen Busharat, Suling Li, Ping Wang
Cancer Immunol Immunother. 2023 May; 72(5): 1139–1151. Published online 2022 Nov 7. doi: 10.1007/s00262-022-03319-w
PMCID:
PMC10110685
AbstractArticlePDF–5.6M
13.
Variations in the poly-histidine repeat motif of HOXA1 contribute to bicuspid aortic valve in mouse and zebrafish
Gaëlle Odelin, Adèle Faucherre, Damien Marchese, Amélie Pinard, Hager Jaouadi, Solena Le Scouarnec, FranceGenRef Consortium, Raphaël Chiarelli, Younes Achouri, Emilie Faure, Marine Herbane, Alexis Théron, Jean-François Avierinos, Chris Jopling, Gwenaëlle Collod-Béroud, René Rezsohazy, Stéphane Zaffran
Nat Commun. 2023; 14: 1543. Published online 2023 Mar 20. doi: 10.1038/s41467-023-37110-x
PMCID:
PMC10027860
AbstractArticlePDF–11M
14.
Serotonin and the ventilatory effects of etonogestrel, a gonane progestin, in a murine model of congenital central hypoventilation syndrome
Alexis Casciato, Lola Bianchi, Manon Reverdy, Fanny Joubert, Roman Delucenay-Clarke, Sandrine Parrot, Nélina Ramanantsoa, Eléonore Sizun, Boris Matrot, Christian Straus, Thomas Similowski, Florence Cayetanot, Laurence Bodineau
Front Endocrinol (Lausanne) 2023; 14: 1077798. Published online 2023 Feb 21. doi: 10.3389/fendo.2023.1077798
PMCID:
PMC9989262
AbstractArticlePDF–5.3M
15.
Celsr1 suppresses Wnt5a-mediated chemoattraction to prevent incorrect rostral migration of facial branchiomotor neurons
Devynn Hummel, Alexandria Becks, Hongsheng Men, Elizabeth C. Bryda, Derrick M. Glasco, Anand Chandrasekhar
Development. 2022 Nov 15; 149(22): dev200553. Published online 2022 Nov 16. doi: 10.1242/dev.200553
PMCID:
PMC9845735
AbstractArticle
16.
Bone morphogenetic protein 2- and estradiol-17β-induced changes in ovarian transcriptome during primordial follicle formation
Prabuddha Chakraborty, Rebecca L Anderson, Shyamal K Roy
Biol Reprod. 2022 Sep; 107(3): 800–812. Published online 2022 May 25. doi: 10.1093/biolre/ioac111
PMCID:
PMC9767675
AbstractArticlePDF–2.7M
17.
Multiple congenital malformations arise from somatic mosaicism for constitutively active Pik3ca signaling
Elise Marechal, Anne Poliard, Kilian Henry, Mathias Moreno, Mathilde Legrix, Nicolas Macagno, Grégoire Mondielli, Teddy Fauquier, Anne Barlier, Heather C. Etchevers
Front Cell Dev Biol. 2022; 10: 1013001. Published online 2022 Oct 24. doi: 10.3389/fcell.2022.1013001
PMCID:
PMC9637999
AbstractArticlePDF–7.1M
18.
Egr2 contributes to age-dependent vulnerability to sevoflurane-induced cognitive deficits in mice
Ye-ru Chen, Shu-xia Zhang, Man Fang, Piao Zhang, You-fa Zhou, Xin Yu, Xiang-nan Zhang, Gang Chen
Acta Pharmacol Sin. 2022 Nov; 43(11): 2828–2840. Published online 2022 May 16. doi: 10.1038/s41401-022-00915-5
PMCID:
PMC9622904
AbstractArticlePDF–3.5M
19.
Susceptibility to kidney fibrosis in mice is associated with early growth response-2 protein and tissue inhibitor of metaloproteinase-1 expression
Gábor Kökény, Ágnes Németh, Jeffrey B. Kopp, Weiping Chen, Andrew J. Oler, Anna Manzéger, László Rosivall, Miklós M. Mózes
Kidney Int. Author manuscript; available in PMC 2023 Aug 1.
Published in final edited form as: Kidney Int. 2022 Aug; 102(2): 337–354. Published online 2022 May 2. doi: 10.1016/j.kint.2022.03.029
PMCID:
PMC9393427
AbstractArticlePDF–4.5M
20.
EGR2 is a hub-gene in myocardial infarction and aggravates inflammation and apoptosis in hypoxia-induced cardiomyocytes
Zhixiang Bo, Shuwen Huang, Li Li, Lin Chen, Ping Chen, Xiaoyi Luo, Fang Shi, Bing Zhu, Lin Shen
BMC Cardiovasc Disord. 2022; 22: 373. Published online 2022 Aug 15. doi: 10.1186/s12872-022-02814-3
PMCID:
PMC9377070
AbstractArticlePDF–3.3M

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