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Items: 1 to 20 of 30

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Loss of epigenetic regulation disrupts lineage integrity, induces aberrant alveogenesis and promotes breast cancer
Ellen Langille, Khalid N. Al-Zahrani, Zhibo Ma, Minggao Liang, Liis Uuskula-Reimand, Roderic Espin, Katie Teng, Ahmad Malik, Helga Bergholtz, Samah El Ghamrasni, Somaieh Afiuni-Zadeh, Ricky Tsai, Sana Alvi, Andrew Elia, YiQing Lü, Robin H. Oh, Katelyn J. Kozma, Daniel Trcka, Masahiro Narimatsu, Jeff C. Liu, Thomas Nguyen, Seda Barutcu, Sampath K. Loganathan, Rod Bremner, Gary D. Bader, Sean E. Egan, David W. Cescon, Therese Sørlie, Jeffrey L. Wrana, Hartland W. Jackson, Michael D. Wilson, Agnieszka K. Witkiewicz, Erik S. Knudsen, Miguel Angel Pujana, Geoffrey M. Wahl, Daniel Schramek
Cancer Discov. Author manuscript; available in PMC 2023 Jun 2.
Published in final edited form as: Cancer Discov. 2022 Dec 2; 12(12): 2930–2953. doi: 10.1158/2159-8290.CD-21-0865
PMCID:
PMC9812400
AbstractArticlePDF–4.5M
3.
ASXL1/2 mutations and myeloid malignancies
Edward A. Medina, Caroline R. Delma, Feng-Chun Yang
J Hematol Oncol. 2022; 15: 127. Published online 2022 Sep 6. doi: 10.1186/s13045-022-01336-x
PMCID:
PMC9450349
AbstractArticlePDF–1.8M
4.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
5.
BAP1/ASXL complex modulation regulates epithelial-mesenchymal transition during trophoblast differentiation and invasion
Vicente Perez-Garcia, Georgia Lea, Pablo Lopez-Jimenez, Hanneke Okkenhaug, Graham J Burton, Ashley Moffett, Margherita Y Turco, Myriam Hemberger
eLife. 2021; 10: e63254. Published online 2021 Jun 25. doi: 10.7554/eLife.63254
PMCID:
PMC8233037
AbstractArticlePDF–4.9M
6.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
7.
Role of Asxl2 in non-alcoholic steatohepatitis-related hepatocellular carcinoma developed from diabetes
Zhiqiu Hu, Ziping Zhang, Fei Teng, Jinfeng Feng, Xubo Wu, Qimeng Chang
Int J Mol Med. 2021 Jan; 47(1): 101–112. Published online 2020 Nov 4. doi: 10.3892/ijmm.2020.4782
PMCID:
PMC7723516
AbstractArticlePDF–1.7M
8.
Myeloid-specific Asxl2 deletion limits diet-induced obesity by regulating energy expenditure
Wei Zou, Nidhi Rohatgi, Jonathan R. Brestoff, John R. Moley, Yongjia Li, Jesse W. Williams, Yael Alippe, Hua Pan, Terri A. Pietka, Gabriel Mbalaviele, Elizabeth P. Newberry, Nicholas O. Davidson, Anwesha Dey, Kooresh I. Shoghi, Richard D. Head, Samuel A. Wickline, Gwendalyn J. Randolph, Nada A. Abumrad, Steven L. Teitelbaum
J Clin Invest. 2020 May 1; 130(5): 2644–2656. Published online 2020 Apr 20. doi: 10.1172/JCI128687
PMCID:
PMC7190927
AbstractArticlePDF–7.1M
9.
ASXL2 regulates hematopoiesis in mice and its deficiency promotes myeloid expansion
Vikas Madan, Lin Han, Norimichi Hattori, Weoi Woon Teoh, Anand Mayakonda, Qiao-Yang Sun, Ling-Wen Ding, Hazimah Binte Mohd Nordin, Su Lin Lim, Pavithra Shyamsunder, Pushkar Dakle, Janani Sundaresan, Ngan B. Doan, Masashi Sanada, Aiko Sato-Otsubo, Manja Meggendorfer, Henry Yang, Jonathan W. Said, Seishi Ogawa, Torsten Haferlach, Der-Cherng Liang, Lee-Yung Shih, Tsuyoshi Nakamaki, Q. Tian Wang, H. Phillip Koeffler
Haematologica. 2018 Dec; 103(12): 1980–1990. Prepublished online 2018 Aug 9. doi: 10.3324/haematol.2018.189928
PMCID:
PMC6269306
AbstractArticlePDF–2.1M
10.
Asxl2−/− Mice Exhibit De Novo Cardiomyocyte Production during Adulthood
Rachel Brunner, Hsiao-Lei Lai, Zane Deliu, Elan Melman, David L. Geenen, Q. Tian Wang, Simon J. Conway
J Dev Biol. 2016 Dec; 4(4): 32. Published online 2016 Nov 3. doi: 10.3390/jdb4040032
PMCID:
PMC5831801
AbstractArticlePDF–7.8M
11.
Loss of Asxl2 leads to myeloid malignancies in mice
Jianping Li, Fuhong He, Peng Zhang, Shi Chen, Hui Shi, Yanling Sun, Ying Guo, Hui Yang, Na Man, Sarah Greenblatt, Zhaomin Li, Zhengyu Guo, Yuan Zhou, Lan Wang, Lluis Morey, Sion Williams, Xi Chen, Qun-Tian Wang, Stephen D. Nimer, Peng Yu, Qian-Fei Wang, Mingjiang Xu, Feng-Chun Yang
Nat Commun. 2017; 8: 15456. Published online 2017 Jun 8. doi: 10.1038/ncomms15456
PMCID:
PMC5472177
AbstractArticlePDF–11M
12.
ASXL2 is essential for haematopoiesis and acts as a haploinsufficient tumour suppressor in leukemia
Jean-Baptiste Micol, Alessandro Pastore, Daichi Inoue, Nicolas Duployez, Eunhee Kim, Stanley Chun-Wei Lee, Benjamin H. Durham, Young Rock Chung, Hana Cho, Xiao Jing Zhang, Akihide Yoshimi, Andrei Krivtsov, Richard Koche, Eric Solary, Amit Sinha, Claude Preudhomme, Omar Abdel-Wahab
Nat Commun. 2017; 8: 15429. Published online 2017 May 18. doi: 10.1038/ncomms15429
PMCID:
PMC5454368
AbstractArticlePDF–1.9M
13.
Loss of the tumor suppressor BAP1 causes myeloid transformation
Anwesha Dey, Dhaya Seshasayee, Rajkumar Noubade, Dorothy M. French, Jinfeng Liu, Mira S. Chaurushiya, Donald S. Kirkpatrick, Victoria C. Pham, Jennie R. Lill, Corey E. Bakalarski, Jiansheng Wu, Lilian Phu, Paula Katavolos, Lindsay M. Saunders, Omar Abdel-Wahab, Zora Modrusan, Somasekar Seshagiri, Ken Dong, Zhonghua Lin, Mercedesz Balazs, Rowena Suriben, Kim Newton, Sarah Hymowitz, Guillermo Garcia-Manero, Flavius Martin, Ross L. Levine, Vishva M. Dixit
Science. Author manuscript; available in PMC 2016 Dec 30.
Published in final edited form as: Science. 2012 Sep 21; 337(6101): 1541–1546. Published online 2012 Aug 9. doi: 10.1126/science.1221711
PMCID:
PMC5201002
AbstractArticlePDF–1.7M
14.
ASXL2 regulates glucose, lipid and skeletal homeostasis
Takashi Izawa, Nidhi Rohatgi, Tomohiro Fukunaga, Qun-Tian Wang, Matthew J. Silva, Michael J. Gardner, Michael L. McDaniel, Nada A. Abumrad, Clay F. Semenkovich, Steven L. Teitelbaum, Wei Zou
Cell Rep. Author manuscript; available in PMC 2016 Jun 16.
Published in final edited form as: Cell Rep. 2015 Jun 16; 11(10): 1625–1637. Published online 2015 Jun 4. doi: 10.1016/j.celrep.2015.05.019
PMCID:
PMC4472564
AbstractArticlePDF–2.0M
15.
Additional Sex Combs-Like 2 Is Required for Polycomb Repressive Complex 2 Binding at Select Targets
Hsiao-Lei Lai, Q. Tian Wang
PLoS One. 2013; 8(9): e73983. Published online 2013 Sep 9. doi: 10.1371/journal.pone.0073983
PMCID:
PMC3767597
AbstractArticlePDF–1.5M
16.
Maintenance of adult cardiac function requires the chromatin factor Asxl2
Hsiao-Lei Lai, Milana Grachoff, Andrea L. Marion, Farida F. Khan, Chad M. Warren, Shamim A.K. Chowdhury, Beata M. Wolska, R. John Solaro, David L. Geenen, Q. Tian Wang
J Mol Cell Cardiol. Author manuscript; available in PMC 2013 Nov 1.
Published in final edited form as: J Mol Cell Cardiol. 2012 Nov; 53(5): 734–741. Published online 2012 Aug 27. doi: 10.1016/j.yjmcc.2012.08.014
PMCID:
PMC3472135
AbstractArticlePDF–1.7M
17.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
18.
Mouse Genome-Wide Association and Systems Genetics Identify Asxl2 As a Regulator of Bone Mineral Density and Osteoclastogenesis
Charles R. Farber, Brian J. Bennett, Luz Orozco, Wei Zou, Ana Lira, Emrah Kostem, Hyun Min Kang, Nicholas Furlotte, Ani Berberyan, Anatole Ghazalpour, Jaijam Suwanwela, Thomas A. Drake, Eleazar Eskin, Q. Tian Wang, Steven L. Teitelbaum, Aldons J. Lusis
PLoS Genet. 2011 Apr; 7(4): e1002038. Published online 2011 Apr 7. doi: 10.1371/journal.pgen.1002038
PMCID:
PMC3072371
AbstractArticlePDF–3.5M
19.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M
20.
Functional Conservation of Asxl2, a Murine Homolog for the Drosophila Enhancer of Trithorax and Polycomb Group Gene Asx
Heather A. Baskind, Lucy Na, Quanhong Ma, Mayur P. Patel, David L. Geenen, Q. Tian Wang
PLoS One. 2009; 4(3): e4750. Published online 2009 Mar 9. doi: 10.1371/journal.pone.0004750
PMCID:
PMC2650259
AbstractArticlePDF–1.0M

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