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Items: 1 to 20 of 56

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
LIN28B promotes differentiation of fully transformed AML cells but is dispensable for fetal leukemia suppression
Yanan Li, Jonny Mendoza-Castrejon, Riddhi M. Patel, Emily B. Casey, Elisabeth Denby, David Bryder, Jeffrey A. Magee
Leukemia. 2024; 38(3): 648–651. Published online 2024 Feb 6. doi: 10.1038/s41375-024-02167-0
PMCID:
PMC10912017
ArticlePDF–1.0M
3.
Growth-suppressor microRNAs mediate synaptic overgrowth and behavioral deficits in Fragile X mental retardation protein deficiency
Megha Subramanian, William T. Mills, IV, Manish D. Paranjpe, Uche S. Onuchukwu, Manasi Inamdar, Amanda R. Maytin, Xinbei Li, Joel L. Pomerantz, Mollie K. Meffert
iScience. 2024 Jan 19; 27(1): 108676. Published online 2023 Dec 12. doi: 10.1016/j.isci.2023.108676
PMCID:
PMC10792201
AbstractArticlePDF–5.0M
4.
The Lin28b/Wnt5a axis drives pancreas cancer through crosstalk between cancer associated fibroblasts and tumor epithelium
Zhaoqi Shu, Minghe Fan, Bo Tu, Zhiheng Tang, Haojie Wang, Haimeng Li, Hengchao Li, Meng Yuan, Jingru Bai, Sihan Huo, Lina Wang, Wei-Guo Zhu, Wei Wang, Xiaoyun Liu, Shaokun Shu, Ying Zhao
Nat Commun. 2023; 14: 6885. Published online 2023 Oct 28. doi: 10.1038/s41467-023-42508-8
PMCID:
PMC10613206
AbstractArticlePDF–4.8M
5.
Lin28 regulates thymic growth and involution and correlates with MHCII expression in thymic epithelial cells
Shiyun Xiao, Wen Zhang, Jie Li, Nancy R. Manley
Front Immunol. 2023; 14: 1261081. Published online 2023 Oct 6. doi: 10.3389/fimmu.2023.1261081
PMCID:
PMC10588642
AbstractArticlePDF–7.5M
6.
Enhanced protein synthesis is a defining requirement for neonatal B cell development
Hugo Åkerstrand, Elena Boldrin, Giorgia Montano, Stijn Vanhee, Karin Olsson, Niklas Krausse, Stefano Vergani, Maciej Cieśla, Cristian Bellodi, Joan Yuan
Front Immunol. 2023; 14: 1130930. Published online 2023 Apr 17. doi: 10.3389/fimmu.2023.1130930
PMCID:
PMC10149930
AbstractArticlePDF–4.3M
7.
Developmental cues license megakaryocyte priming in murine hematopoietic stem cells
Trine A. Kristiansen, Qinyu Zhang, Stefano Vergani, Elena Boldrin, Niklas Krausse, Oscar André, Pontus Nordenfelt, Mikael Sigvardsson, David Bryder, Jonas Ungerbäck, Joan Yuan
Blood Adv. 2022 Dec 27; 6(24): 6228–6241. Published online 2022 May 20. doi: 10.1182/bloodadvances.2021006861
PMCID:
PMC9792704
AbstractArticlePDF–1.6M
8.
Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis
Dahai Wang, Mayuri Tanaka-Yano, Eleanor Meader, Melissa A. Kinney, Vivian Morris, Edroaldo Lummertz da Rocha, Nan Liu, Tianxin Liu, Qian Zhu, Stuart H. Orkin, Trista E. North, George Q. Daley, R. Grant Rowe
Cell Rep. Author manuscript; available in PMC 2022 Apr 22.
Published in final edited form as: Cell Rep. 2022 Apr 5; 39(1): 110587. doi: 10.1016/j.celrep.2022.110587
PMCID:
PMC9029260
AbstractArticlePDF–3.1M
9.
Lin28 paralogs regulate lung branching morphogenesis
Jihan K. Osborne, Melissa A. Kinney, Areum Han, Kemi E. Akinnola, Alena V. Yermalovich, Linda T. Vo, Daniel S. Pearson, Patricia M. Sousa, Sutheera Ratanasirintrawoot, Kaloyan M. Tsanov, Jessica Barragan, Trista E. North, Ross J. Metzger, George Q. Daley
Cell Rep. Author manuscript; available in PMC 2021 Aug 18.
Published in final edited form as: Cell Rep. 2021 Jul 20; 36(3): 109408. doi: 10.1016/j.celrep.2021.109408
PMCID:
PMC8371695
AbstractArticlePDF–1.5M
10.
LIN28B induces a differentiation program through CDX2 in colon cancer
Kensuke Suzuki, Yasunori Masuike, Rei Mizuno, Uma M. Sachdeva, Priya Chatterji, Sarah F. Andres, Wenping Sun, Andres J. Klein-Szanto, Sepideh Besharati, Helen E. Remotti, Michael P. Verzi, Anil K. Rustgi
JCI Insight. 2021 May 10; 6(9): e140382. Published online 2021 May 10. doi: 10.1172/jci.insight.140382
PMCID:
PMC8262288
AbstractArticlePDF–4.0M
11.
LIN28B/let-7 control the ability of neonatal murine auditory supporting cells to generate hair cells through mTOR signaling
Xiao-Jun Li, Angelika Doetzlhofer
Proc Natl Acad Sci U S A. 2020 Sep 8; 117(36): 22225–22236. Published online 2020 Aug 21. doi: 10.1073/pnas.2000417117
PMCID:
PMC7486708
AbstractArticlePDF–2.0M
12.
An ontogenetic switch drives the positive and negative selection of B cells
Xijin Xu, Mukta Deobagkar-Lele, Katherine R. Bull, Tanya L. Crockford, Adam J. Mead, Adam P. Cribbs, David Sims, Consuelo Anzilotti, Richard J. Cornall
Proc Natl Acad Sci U S A. 2020 Feb 18; 117(7): 3718–3727. Published online 2020 Feb 4. doi: 10.1073/pnas.1915247117
PMCID:
PMC7035474
AbstractArticlePDF–1.8M
13.
LIN28A loss of function is associated with Parkinson's disease pathogenesis
Mi‐Yoon Chang, Boram Oh, Jang‐Eun Choi, Yanuar Alan Sulistio, Hye‐Ji Woo, Ayoung Jo, Jinil Kim, Eun‐Hee Kim, Seung Won Kim, Jungwook Hwang, Jungyun Park, Jae‐Jin Song, Oh‐Chan Kwon, Hyongbum Henry Kim, Young‐Hoon Kim, Joo Yeon Ko, Jun Young Heo, Min Joung Lee, Moses Lee, Murim Choi, Sun Ju Chung, Hyun‐Seob Lee, Sang‐Hun Lee
EMBO J. 2019 Dec 16; 38(24): e101196. Published online 2019 Nov 21. doi: 10.15252/embj.2018101196
PMCID:
PMC6912061
AbstractArticlePDF–4.8M
14.
Genomic architecture of Shh-dependent cochlear morphogenesis
Victor Muthu, Alex M. Rohacek, Yao Yao, Staci M. Rakowiecki, Alexander S. Brown, Ying-Tao Zhao, James Meyers, Kyoung-Jae Won, Shweta Ramdas, Christopher D. Brown, Kevin A. Peterson, Douglas J. Epstein
Development. 2019 Sep 15; 146(18): dev181339. Published online 2019 Sep 19. doi: 10.1242/dev.181339
PMCID:
PMC6765179
AbstractArticle
15.
Enhancement of LIN28B-induced hematopoietic reprogramming by IGF2BP3
Saifeng Wang, Bryan Chim, Yijun Su, Pavel Khil, Madeline Wong, Xiantao Wang, Amir Foroushani, Patrick T. Smith, Xiuhuai Liu, Rui Li, Sundar Ganesan, Chrysi Kanellopoulou, Markus Hafner, Stefan A. Muljo
Genes Dev. 2019 Aug 1; 33(15-16): 1048–1068. doi: 10.1101/gad.325100.119
PMCID:
PMC6672051
AbstractArticlePDF–5.2M
16.
Lin28B and Let-7 in the Control of Sympathetic Neurogenesis and Neuroblastoma Development
Melanie Hennchen, Jutta Stubbusch, Ikram Abarchan-El Makhfi, Marco Kramer, Thomas Deller, Cécile Pierre-Eugene, Isabelle Janoueix-Lerosey, Olivier Delattre, Uwe Ernsberger, Johannes B. Schulte, Hermann Rohrer
J Neurosci. 2015 Dec 16; 35(50): 16531–16544. doi: 10.1523/JNEUROSCI.2560-15.2015
PMCID:
PMC6605513
AbstractArticlePDF–4.6M
17.
C/EBPβ-LIP induces cancer-type metabolic reprogramming by regulating the let-7/LIN28B circuit in mice
Tobias Ackermann, Götz Hartleben, Christine Müller, Guido Mastrobuoni, Marco Groth, Britt A. Sterken, Mohamad A. Zaini, Sameh A. Youssef, Hidde R. Zuidhof, Sara R. Krauss, Gertrud Kortman, Gerald de Haan, Alain de Bruin, Zhao-Qi Wang, Matthias Platzer, Stefan Kempa, Cornelis F. Calkhoven
Commun Biol. 2019; 2: 208. Published online 2019 Jun 14. doi: 10.1038/s42003-019-0461-z
PMCID:
PMC6572810
AbstractArticlePDF–2.0M
18.
Lin28-mediated temporal promotion of protein synthesis is crucial for neural progenitor cell maintenance and brain development in mice
Stephanie Herrlinger, Qiang Shao, Mei Yang, Qing Chang, Yang Liu, Xiaohan Pan, Hang Yin, Li-Wei Xie, Jian-Fu Chen
Development. 2019 May 15; 146(10): dev173765. Published online 2019 May 28. doi: 10.1242/dev.173765
PMCID:
PMC6550015
AbstractArticle
19.
Lin28 and let-7 regulate the timing of cessation of murine nephrogenesis
Alena V. Yermalovich, Jihan K. Osborne, Patricia Sousa, Areum Han, Melissa A. Kinney, Michael J. Chen, Daisy A. Robinton, Helen Montie, Dan S. Pearson, Sean B. Wilson, Alexander N. Combes, Melissa H. Little, George Q. Daley
Nat Commun. 2019; 10: 168. Published online 2019 Jan 11. doi: 10.1038/s41467-018-08127-4
Correction in:
Nat Commun. 2020; 11: 1327.
PMCID:
PMC6329821
AbstractArticlePDF–2.4M
20.
Lin28b regulates age-dependent differences in murine platelet function
Massiel Chavez Stolla, Seana C. Catherman, Paul D. Kingsley, R. Grant Rowe, Anne D. Koniski, Katherine Fegan, Leah Vit, Kathleen E. McGrath, George Q. Daley, James Palis
Blood Adv. 2019 Jan 8; 3(1): 72–82. Published online 2019 Jan 8. doi: 10.1182/bloodadvances.2018020859
PMCID:
PMC6325299
AbstractArticlePDF–1.3M

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