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Items: 1 to 20 of 41

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
miR-195b is required for proper cellular homeostasis in the elderly
Maria del Mar Muñoz-Gallardo, Carlos Garcia-Padilla, Cristina Vicente-Garcia, Jaime Carvajal, Amelia Arenega, Diego Franco
Sci Rep. 2024; 14: 810. Published online 2024 Jan 8. doi: 10.1038/s41598-024-51256-8
PMCID:
PMC10774362
AbstractArticlePDF–3.7M
3.
ALS-linked loss of Cyclin-F function affects HSP90
Alexander Siebert, Vanessa Gattringer, Jochen H Weishaupt, Christian Behrends
Life Sci Alliance. 2022 Dec; 5(12): e202101359. Published online 2022 Sep 16. doi: 10.26508/lsa.202101359
PMCID:
PMC9481933
AbstractArticlePDF–3.5M
4.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
5.
Glutathione reductase deficiency alters lung development and hyperoxic responses in neonatal mice
Mary E. Robbins, Hye-Youn Cho, Jason M. Hansen, Joseph R. Luchsinger, Morgan L. Locy, Markus Velten, Steven R. Kleeberger, Lynette K. Rogers, Trent E. Tipple
Redox Biol. 2021 Jan; 38: 101797. Published online 2020 Nov 13. doi: 10.1016/j.redox.2020.101797
PMCID:
PMC7708869
AbstractArticlePDF–8.6M
6.
How Does Ginsenoside Rh2 Mitigate Adipogenesis in Cultured Cells and Obese Mice?
Longyun Zhang, Carlos Virgous, Hongwei Si
Molecules. 2020 May; 25(10): 2412. Published online 2020 May 21. doi: 10.3390/molecules25102412
PMCID:
PMC7287807
AbstractArticlePDF–1.5M
7.
Glutathione Reductase Promotes Fungal Clearance and Suppresses Inflammation during Systemic Candida albicans Infection in Mice
Victoria Y. Kim, Abel Batty, Jinhui Li, Sean G. Kirk, Yi Jin, Juan Tang, Jian Zhang, Lynette K. Rogers, Han-Xiang Deng, Leif D. Nelin, Yusen Liu
J Immunol. Author manuscript; available in PMC 2020 Oct 15.
Published in final edited form as: J Immunol. 2019 Oct 15; 203(8): 2239–2251. Published online 2019 Sep 9. doi: 10.4049/jimmunol.1701686
PMCID:
PMC6783371
AbstractArticlePDF–2.9M
8.
The pluripotency transcription factor Nanog represses glutathione reductase gene expression in mouse embryonic stem cells
Claudia Solari, María Victoria Petrone, Ayelén Toro, Camila Vazquez Echegaray, María Soledad Cosentino, Ariel Waisman, Marcos Francia, Lino Barañao, Santiago Miriuka, Alejandra Guberman
BMC Res Notes. 2019; 12: 370. Published online 2019 Jul 1. doi: 10.1186/s13104-019-4411-0
PMCID:
PMC6604252
AbstractArticlePDF–2.8M
9.
Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma
Abigail G Zieman, Brian G Poll, Jingqun Ma, Pierre A Coulombe
Hum Mol Genet. 2019 Jul 1; 28(13): 2255–2270. Published online 2019 Mar 20. doi: 10.1093/hmg/ddz050
PMCID:
PMC6602407
AbstractArticlePDF–3.5M
10.
TrxR1, Gsr, and oxidative stress determine hepatocellular carcinoma malignancy
Michael R. McLoughlin, David J. Orlicky, Justin R. Prigge, Pushya Krishna, Emily A. Talago, Ian R. Cavigli, Sofi Eriksson, Colin G. Miller, Jean A. Kundert, Volkan I. Sayin, Rachel A. Sabol, Joshua Heinemann, Luke O. Brandenberger, Sonya V. Iverson, Brian Bothner, Thales Papagiannakopoulos, Colin T. Shearn, Elias S. J. Arnér, Edward E. Schmidt
Proc Natl Acad Sci U S A. 2019 Jun 4; 116(23): 11408–11417. Published online 2019 May 16. doi: 10.1073/pnas.1903244116
PMCID:
PMC6561278
AbstractArticlePDF–3.2M
11.
Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss
Adelaida M Celaya, Isabel Sánchez-Pérez, Jose M Bermúdez-Muñoz, Lourdes Rodríguez-de la Rosa, Laura Pintado-Berninches, Rosario Perona, Silvia Murillo-Cuesta, Isabel Varela-Nieto
eLife. 2019; 8: e39159. Published online 2019 Apr 2. doi: 10.7554/eLife.39159
PMCID:
PMC6464786
AbstractArticlePDF–5.9M
12.
Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors
Hyeonwoo Kim, Christiane D. Wrann, Mark Jedrychowski, Sara Vidoni, Yukiko Kitase, Kenichi Nagano, Chenhe Zhou, Joshua Chou, Virginia-Jeni A. Parkman, Scott J. Novick, Timothy S. Strutzenberg, Bruce D. Pascal, Phuong T. Le, Daniel J. Brooks, Alexander M. Roche, Kaitlyn K. Gerber, Laura Mattheis, Wenjing Chen, Hua Tu, Mary L. Bouxsein, Patrick R. Griffin, Roland Baron, Clifford J. Rosen, Lynda F. Bonewald, Bruce M. Spiegelman
Cell. Author manuscript; available in PMC 2019 Dec 13.
Published in final edited form as: Cell. 2018 Dec 13; 175(7): 1756–1768.e17. doi: 10.1016/j.cell.2018.10.025
Correction in:
Cell. 2019 Jul 11; 178(2): 507–508.
PMCID:
PMC6298040
AbstractArticlePDF–1.2M
13.
Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation
Gaojian Lian, JN Rashida Gnanaprakasam, Tingting Wang, Ruohan Wu, Xuyong Chen, Lingling Liu, Yuqing Shen, Mao Yang, Jun Yang, Ying Chen, Vasilis Vasiliou, Teresa A Cassel, Douglas R Green, Yusen Liu, Teresa WM Fan, Ruoning Wang
eLife. 2018; 7: e36158. Published online 2018 Sep 10. doi: 10.7554/eLife.36158
PMCID:
PMC6152796
AbstractArticlePDF–2.2M
14.
Hepatocyte Hyperproliferation upon Liver-Specific Co-disruption of Thioredoxin-1, Thioredoxin Reductase-1, and Glutathione Reductase
Justin R. Prigge, Lucia Coppo, Sebastin S. Martin, Fernando Ogata, Colin G. Miller, Michael D. Bruschwein, David J. Orlicky, Colin T. Shearn, Jean A. Kundert, Julia Lytchier, Alix E. Herr, Åse Mattsson, Matthew P. Taylor, Tomas N. Gustafsson, Elias S.J. Arnér, Arne Holmgren, Edward E. Schmidt
Cell Rep. Author manuscript; available in PMC 2017 Dec 14.
Published in final edited form as: Cell Rep. 2017 Jun 27; 19(13): 2771–2781. doi: 10.1016/j.celrep.2017.06.019
PMCID:
PMC5730093
AbstractArticlePDF–2.9M
15.
GSR is not essential for the maintenance of antioxidant defenses in mouse cochlea: Possible role of the thioredoxin system as a functional backup for GSR
Chul Han, Mi-Jung Kim, Dalian Ding, Hyo-Jin Park, Karessa White, Logan Walker, Tongjun Gu, Masaru Tanokura, Tatsuya Yamasoba, Paul Linser, Richard Salvi, Shinichi Someya
PLoS One. 2017; 12(7): e0180817. Published online 2017 Jul 7. doi: 10.1371/journal.pone.0180817
PMCID:
PMC5501606
AbstractArticlePDF–4.8M
16.
cGMP Signaling Increases Antioxidant Gene Expression by Activating Forkhead Box O3A in the Colon Epithelium
Rui Wang, Bianca N. Islam, Allison Bridges, Sarah K. Sharman, Muhan Hu, Yali Hou, Payaningal R. Somanath, Laine Venable, Nagendra Singh, Sangmi Kim, Subbaramiah Sridhar, Franz Hofmann, Darren D. Browning
Am J Pathol. 2017 Feb; 187(2): 377–389. doi: 10.1016/j.ajpath.2016.10.016
PMCID:
PMC5389370
AbstractArticlePDF–1.9M
17.
Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury
Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa
PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355
PMCID:
PMC5045200
AbstractArticlePDF–2.9M
18.
Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin
Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu
J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029
PMCID:
PMC4576858
AbstractArticlePDF–3.0M
19.
Dietary methionine can sustain cytosolic redox homeostasis in the mouse liver
Sofi Eriksson, Justin R. Prigge, Emily A. Talago, Elias S. J. Arnér, Edward E. Schmidt
Nat Commun. Author manuscript; available in PMC 2015 Sep 20.
Published in final edited form as: Nat Commun. 2015; 6: 6479. Published online 2015 Mar 20. doi: 10.1038/ncomms7479
PMCID:
PMC4369796
AbstractArticlePDF–2.9M
20.
Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization
Erin J. Plosa, Lisa R. Young, Peter M. Gulleman, Vasiliy V. Polosukhin, Rinat Zaynagetdinov, John T. Benjamin, Amanda M. Im, Riet van der Meer, Linda A. Gleaves, Nada Bulus, Wei Han, Lawrence S. Prince, Timothy S. Blackwell, Roy Zent
Development. 2014 Dec 15; 141(24): 4751–4762. doi: 10.1242/dev.117200
PMCID:
PMC4299273
AbstractArticle

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