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Items: 1 to 20 of 88

1.
The NLR member CIITA: Master controller of adaptive and intrinsic immunity and unexpected tool in cancer immunotherapy
Greta Forlani, Mariam Shallak, Andrea Gatta, Amruth K.B. Shaik, Roberto S. Accolla
Biomed J. 2023 Oct; 46(5): 100631. Published online 2023 Jul 17. doi: 10.1016/j.bj.2023.100631
PMCID:
PMC10505679
AbstractArticlePDF–1.6M
2.
FBXO11 constitutes a major negative regulator of MHC class II through ubiquitin-dependent proteasomal degradation of CIITA
Yusuke Kasuga, Ryota Ouda, Masashi Watanabe, Xin Sun, Miki Kimura, Shigetsugu Hatakeyama, Koichi S. Kobayashi
Proc Natl Acad Sci U S A. 2023 Jun 13; 120(24): e2218955120. Published online 2023 Jun 6. doi: 10.1073/pnas.2218955120
PMCID:
PMC10268274
AbstractArticlePDF–2.3M
3.
NLRC5-CIITA Fusion Protein as an Effective Inducer of MHC-I Expression and Antitumor Immunity
Madanraj Appiya Santharam, Akhil Shukla, Dominique Levesque, Thomas A. Kufer, François-Michel Boisvert, Sheela Ramanathan, Subburaj Ilangumaran
Int J Mol Sci. 2023 Apr; 24(8): 7206. Published online 2023 Apr 13. doi: 10.3390/ijms24087206
PMCID:
PMC10138588
AbstractArticlePDF–2.8M
4.
The MHC Class II Transactivator CIITA: Not (Quite) the Odd-One-Out Anymore among NLR Proteins
Jorge Alfonso León Machado, Viktor Steimle
Int J Mol Sci. 2021 Feb; 22(3): 1074. Published online 2021 Jan 22. doi: 10.3390/ijms22031074
PMCID:
PMC7866136
AbstractArticlePDF–1.0M
5.
MHC class II transactivator CIITA induces cell resistance to Ebola virus and SARS-like coronaviruses
Anna Bruchez, Ky Sha, Joshua Johnson, Li Chen, Caroline Stefani, Hannah McConnell, Lea Gaucherand, Rachel Prins, Kenneth A. Matreyek, Adam J. Hume, Elke Mühlberger, Emmett V. Schmidt, Gene G. Olinger, Lynda M. Stuart, Adam Lacy-Hulbert
Science. 2020 Oct 9; 370(6513): 241–247. Published online 2020 Aug 27. doi: 10.1126/science.abb3753
PMCID:
PMC7665841
AbstractArticlePDF–1.5M
6.
Inhibition of the CtBP complex and FBXO11 enhances MHC class II expression and anti-cancer immune responses
Kah Lok Chan, Juliana Gomez, Chelisa Cardinez, Nishi Kumari, Christina E. Sparbier, Enid Y.N. Lam, Miriam M. Yeung, Sylvain Garciaz, James A. Kuzich, Doen Ming Ong, Fiona C. Brown, Yih-Chih Chan, Dane Vassiliadis, Elanor N. Wainwright, Ali Motazedian, Andrea Gillespie, Katie A. Fennell, Junyun Lai, Imran G. House, Laura Macpherson, Ching-Seng Ang, Sarah-Jane Dawson, Paul A. Beavis, Andrew H. Wei, Marian L. Burr, Mark A. Dawson
Cancer Cell. Author manuscript; available in PMC 2023 Oct 10.
Published in final edited form as: Cancer Cell. 2022 Oct 10; 40(10): 1190–1206.e9. Published online 2022 Sep 29. doi: 10.1016/j.ccell.2022.09.007
PMCID:
PMC7615013
AbstractArticlePDF–3.2M
7.
Helicobacter pylori Dampens HLA-II Expression on Macrophages via the Up-Regulation of miRNAs Targeting CIITA
Gaia Codolo, Marta Toffoletto, Francesco Chemello, Sara Coletta, Gemma Soler Teixidor, Greta Battaggia, Giada Munari, Matteo Fassan, Stefano Cagnin, Marina de Bernard
Front Immunol. 2019; 10: 2923. Published online 2020 Jan 8. doi: 10.3389/fimmu.2019.02923
PMCID:
PMC6960189
AbstractArticlePDF–1.4M
8.
CIITA-Driven MHC Class II Expressing Tumor Cells as Antigen Presenting Cell Performers: Toward the Construction of an Optimal Anti-tumor Vaccine
Roberto S. Accolla, Elise Ramia, Alessandra Tedeschi, Greta Forlani
Front Immunol. 2019; 10: 1806. Published online 2019 Jul 30. doi: 10.3389/fimmu.2019.01806
PMCID:
PMC6682709
AbstractArticlePDF–860K
9.
Fowlpoxvirus recombinants coding for the CIITA gene increase the expression of endogenous MHC-II and Fowlpox Gag/Pro and Env SIV transgenes
Massimiliano Bissa, Greta Forlani, Carlo Zanotto, Giovanna Tosi, Carlo De Giuli Morghen, Roberto S. Accolla, Antonia Radaelli
PLoS One. 2018; 13(1): e0190869. Published online 2018 Jan 31. doi: 10.1371/journal.pone.0190869
PMCID:
PMC5791965
AbstractArticlePDF–4.0M
10.
Genome-Wide Analysis in Brazilians Reveals Highly Differentiated Native American Genome Regions
Josyf C. Mychaleckyj, Alexandre Havt, Uma Nayak, Relana Pinkerton, Emily Farber, Patrick Concannon, Aldo A. Lima, Richard L. Guerrant
Mol Biol Evol. 2017 Mar; 34(3): 559–574. Published online 2017 Jan 18. doi: 10.1093/molbev/msw249
PMCID:
PMC5430616
AbstractArticlePDF–1.6M
11.
Tripartite Motif-Containing Protein 22 Interacts with Class II Transactivator and Orchestrates Its Recruitment in Nuclear Bodies Containing TRIM19/PML and Cyclin T1
Greta Forlani, Giovanna Tosi, Filippo Turrini, Guido Poli, Elisa Vicenzi, Roberto S. Accolla
Front Immunol. 2017; 8: 564. Published online 2017 May 15. doi: 10.3389/fimmu.2017.00564
PMCID:
PMC5430032
AbstractArticlePDF–2.5M
12.
Repression of CIITA by the Epstein–Barr virus transcription factor Zta is independent of its dimerization and DNA binding
Nicolae Balan, Kay Osborn, Alison J. Sinclair
J Gen Virol. 2016 Mar; 97(Pt 3): 725–732. Published online 2016 Mar 1. doi: 10.1099/jgv.0.000369
PMCID:
PMC5381392
AbstractArticlePDF–345K
13.
Pulling a Ligase out of a “HAT”: pCAF Mediates Ubiquitination of the Class II Transactivator
Julie E. Morgan, Susanna F. Greer
Int J Cell Biol. 2017; 2017: 8093813. Published online 2017 Feb 12. doi: 10.1155/2017/8093813
PMCID:
PMC5327758
AbstractArticlePDF–1.4M
14.
Role of PU.1 in MHC Class II Expression via CIITA Transcription in Plasmacytoid Dendritic Cells
Ryosuke Miura, Kazumi Kasakura, Nobuhiro Nakano, Mutsuko Hara, Keiko Maeda, Ko Okumura, Hideoki Ogawa, Takuya Yashiro, Chiharu Nishiyama
PLoS One. 2016; 11(4): e0154094. Published online 2016 Apr 22. doi: 10.1371/journal.pone.0154094
PMCID:
PMC4841550
AbstractArticlePDF–1.0M
15.
The MHC-II transactivator CIITA inhibits Tat function and HIV-1 replication in human myeloid cells
Greta Forlani, Filippo Turrini, Silvia Ghezzi, Alessandra Tedeschi, Guido Poli, Roberto S. Accolla, Giovanna Tosi
J Transl Med. 2016; 14: 94. Published online 2016 Apr 18. doi: 10.1186/s12967-016-0853-5
PMCID:
PMC4835826
AbstractArticlePDF–1.4M
16.
The Major Histocompatibility Complex Class II Transactivator CIITA Inhibits the Persistent Activation of NF-κB by the Human T Cell Lymphotropic Virus Type 1 Tax-1 Oncoprotein
Greta Forlani, Rawan Abdallah, Roberto S. Accolla, Giovanna Tosi
J Virol. 2016 Apr 1; 90(7): 3708–3721. Prepublished online 2016 Jan 20. Published online 2016 Mar 11. doi: 10.1128/JVI.03000-15
PMCID:
PMC4794681
AbstractArticlePDF–2.3M
17.
FOXP1 suppresses immune response signatures and MHC class II expression in activated B-cell-like diffuse large B-cell lymphomas
P J Brown, K K Wong, S L Felce, L Lyne, H Spearman, E J Soilleux, L M Pedersen, M B Møller, T M Green, D M Gascoyne, A H Banham
Leukemia. 2016 Mar; 30(3): 605–616. Prepublished online 2015 Oct 26. Published online 2015 Nov 17. doi: 10.1038/leu.2015.299
PMCID:
PMC4777777
AbstractArticlePDF–1.9M
18.
Degradation, Promoter Recruitment and Transactivation Mediated by the Extreme N-Terminus of MHC Class II Transactivator CIITA Isoform III
Yves B. Beaulieu, Jorge A. Leon Machado, Sylvain Ethier, Luc Gaudreau, Viktor Steimle
PLoS One. 2016; 11(2): e0148753. Published online 2016 Feb 12. doi: 10.1371/journal.pone.0148753
PMCID:
PMC4752451
AbstractArticlePDF–4.4M
19.
The Ciliopathy Protein CC2D2A Associates with NINL and Functions in RAB8-MICAL3-Regulated Vesicle Trafficking
Ruxandra Bachmann-Gagescu, Margo Dona, Lisette Hetterschijt, Edith Tonnaer, Theo Peters, Erik de Vrieze, Dorus A. Mans, Sylvia E. C. van Beersum, Ian G. Phelps, Heleen H. Arts, Jan E. Keunen, Marius Ueffing, Ronald Roepman, Karsten Boldt, Dan Doherty, Cecilia B. Moens, Stephan C. F. Neuhauss, Hannie Kremer, Erwin van Wijk
PLoS Genet. 2015 Oct; 11(10): e1005575. Published online 2015 Oct 20. doi: 10.1371/journal.pgen.1005575
PMCID:
PMC4617701
AbstractArticlePDF–13M
20.
The class II transactivator (CIITA) is regulated by post-translational modification cross-talk between ERK1/2 phosphorylation, mono-ubiquitination and Lys63 ubiquitination
Julie E. Morgan, Ronald L. Shanderson, Nathaniel H. Boyd, Ercan Cacan, Susanna F. Greer
Biosci Rep. 2015 Aug; 35(4): e00233. Prepublished online 2015 Jun 19. Published online 2015 Jul 29. doi: 10.1042/BSR20150091
PMCID:
PMC4613680
AbstractArticlePDF–1.3M

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