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Select item 111959711.

Systems genetics uncover new loci containing functional gene candidates in Mycobacterium tuberculosis-infected Diversity Outbred mice

Daniel M. Gatti, Anna L. Tyler, J Matthew Mahoney, Gary A. Churchill, Bulent Yener, Deniz Koyuncu, Metin N. Gurcan, MK Khalid Niazi, Thomas Tavolara, Adam Gower, Denise Dayao, Emily McGlone, Melanie L. Ginese, Aubrey Specht, Anas Alsharaydeh, Philipe A. Tessier, Sherry L. Kurtz, Karen L. Elkins, Igor Kramnik, Gillian Beamer

PLoS Pathog. 2024 Jun; 20(6): e1011915. Published online 2024 Jun 11. doi: 10.1371/journal.ppat.1011915

PMCID:: PMC11195971

Abstract Article PDF–3.8M

Select item 111798042.

S100a8/9 (S100 Calcium Binding Protein a8/9) Promotes Cardiac Hypertrophy Via Upregulation of FGF23 (Fibroblast Growth Factor 23) in Mice

Yu‐Pei Yuan, Zhuo‐Yu Shen, Teng Teng, Si‐Chi Xu, Chun‐Yan Kong, Xiao‐Feng Zeng, Marion A. Hofmann Bowman, Ling Yan

J Am Heart Assoc. 2024 May 21; 13(10): e028006. Published online 2024 May 10. doi: 10.1161/JAHA.122.028006

PMCID:: PMC11179804

Abstract Article PDF–3.9M

Select item 110326593.

S100A8/9 modulates perturbation and glycolysis of macrophages in allergic asthma mice

Xiaoyi Ji, Chunhua Nie, Yuan Yao, Yu Ma, Huafei Huang, Chuangli Hao

PeerJ. 2024; 12: e17106. Published online 2024 Apr 18. doi: 10.7717/peerj.17106

PMCID:: PMC11032659

Abstract Article PDF–15M

Select item 109074814.

MDSC-derived S100A8/9 contributes to lupus pathogenesis by promoting TLR7-mediated activation of macrophages and dendritic cells

Yonghong Yang, Xin Zhang, Lina Jing, Yucai Xiao, Yangzhe Gao, Yuxin Hu, Shujiao Jia, Guangxi Zhou, Huabao Xiong, Guanjun Dong

Cell Mol Life Sci. 2024 Dec; 81(1): 110. Published online 2024 Mar 1. doi: 10.1007/s00018-024-05155-w

PMCID:: PMC10907481

Abstract Article PDF–10M

Select item 106553235.

Deficiency of S100A8/A9 attenuates pulmonary microvascular leakage in septic mice

Jiang Yu, Boying Zhao, Qiangzhong Pi, Guoxiang Zhou, Zhe Cheng, Can Qu, Xiaowen Wang, Lingwen Kong, Suxin Luo, Dingyuan Du, Yongzheng Guo

Respir Res. 2023; 24: 288. Published online 2023 Nov 17. doi: 10.1186/s12931-023-02594-0

PMCID:: PMC10655323

Abstract Article PDF–5.3M

Select item 102901026.

NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation

Isidoro Cobo, Sumit Paliwal, Cristina Bodas, Irene Felipe, Júlia Melià-Alomà, Ariadna Torres, Jaime Martínez-Villarreal, Marina Malumbres, Fernando García, Irene Millán, Natalia del Pozo, Joo-Cheol Park, Ray J. MacDonald, Javier Muñoz, Raúl Méndez, Francisco X. Real

Nat Commun. 2023; 14: 3761. Published online 2023 Jun 23. doi: 10.1038/s41467-023-39291-x

PMCID:: PMC10290102

Abstract Article PDF–3.4M

Select item 98887257.

Hepatic ribosomal protein S6 (Rps6) insufficiency results in failed bile duct development and loss of hepatocyte viability; a ribosomopathy-like phenotype that is partially p53-dependent

Sarah A. Comerford, Elizabeth A. Hinnant, Yidong Chen, Robert E. Hammer

PLoS Genet. 2023 Jan; 19(1): e1010595. Published online 2023 Jan 19. doi: 10.1371/journal.pgen.1010595

PMCID:: PMC9888725

Abstract Article PDF–6.9M

Select item 98771958.

Intracellular Calprotectin (S100A8/A9) Facilitates DNA Damage Responses and Promotes Apoptosis in Head and Neck Squamous Cell Carcinoma

Prokopios P. Argyris, Flávia Saavedra, Chris Malz, Ian A. Stone, Yuping Wei, William S. Boyle, Karen F. Johnstone, Ali Khammanivong, Mark C. Herzberg

Oral Oncol. Author manuscript; available in PMC 2024 Feb 1.

Published in final edited form as: Oral Oncol. 2023 Feb; 137: 106304. Published online 2023 Jan 4. doi: 10.1016/j.oraloncology.2022.106304

PMCID:: PMC9877195

Abstract Article PDF–2.5M

Select item 97381009.

Role of S100A8/A9 in Platelet–Neutrophil Complex Formation during Acute Inflammation

Julian Revenstorff, Nadine Ludwig, Annika Hilger, Sina Mersmann, Martin Lehmann, Julia Chiara Grenzheuser, Marina Kardell, Julia Bone, Niklas Martin Kötting, Nina Christine Marx, Johannes Roth, Thomas Vogl, Jan Rossaint

Cells. 2022 Dec; 11(23): 3944. Published online 2022 Dec 6. doi: 10.3390/cells11233944

PMCID:: PMC9738100

Abstract Article PDF–1.6M

Select item 973238910.

Protective effects of S100A8 on sepsis mortality: Links to sepsis risk in obesity and diabetes

Daisuke Miyashita, Ryota Inoue, Takahiro Tsuno, Tomoko Okuyama, Mayu Kyohara, Chigusa Nakahashi-Oda, Kuniyuki Nishiyama, Setsuko Fukushima, Yutaro Inada, Yu Togashi, Akira Shibuya, Yasuo Terauchi, Jun Shirakawa

iScience. 2022 Dec 22; 25(12): 105662. Published online 2022 Nov 23. doi: 10.1016/j.isci.2022.105662

PMCID:: PMC9732389

Abstract Article PDF–4.9M

Select item 965234611.

PD-L1 negatively regulates antifungal immunity by inhibiting neutrophil release from bone marrow

Yao Yu, Rong-Rong Wang, Nai-Jun Miao, Jia-Jie Tang, Yun-Wei Zhang, Xiang-Ran Lu, Pei-Yi Yan, Jing Wang, Xin-Ming Jia

Nat Commun. 2022; 13: 6857. Published online 2022 Nov 11. doi: 10.1038/s41467-022-34722-7

PMCID:: PMC9652346

Abstract Article PDF–4.3M

Select item 922138912.

Integrated Analysis Reveals S100a8/a9 Regulates Autophagy and Apoptosis through the MAPK and PI3K-AKT Signaling Pathway in the Early Stage of Myocardial Infarction

Weijue Yi, Rongli Zhu, Xiuyang Hou, Fengmin Wu, Rui Feng

Cells. 2022 Jun; 11(12): 1911. Published online 2022 Jun 13. doi: 10.3390/cells11121911

PMCID:: PMC9221389

Abstract Article PDF–11M

Select item 912250113.

C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9

Saskia-Larissa Jauch-Speer, Marisol Herrera-Rivero, Nadine Ludwig, Bruna Caroline Véras De Carvalho, Leonie Martens, Jonas Wolf, Achmet Imam Chasan, Anika Witten, Birgit Markus, Bernhard Schieffer, Thomas Vogl, Jan Rossaint, Monika Stoll, Johannes Roth, Olesja Fehler

eLife. 2022; 11: e75594. Published online 2022 May 11. doi: 10.7554/eLife.75594

PMCID:: PMC9122501

Abstract Article PDF–1.7M

Select item 880333714.

Translational implications of Th17-skewed inflammation due to genetic deficiency of a cadherin stress sensor

Lisa M. Godsel, Quinn R. Roth-Carter, Jennifer L. Koetsier, Lam C. Tsoi, Amber L. Huffine, Joshua A. Broussard, Gillian N. Fitz, Sarah M. Lloyd, Junghun Kweon, Hope E. Burks, Marihan Hegazy, Saki Amagai, Paul W. Harms, Xianying Xing, Joseph Kirma, Jodi L. Johnson, Gloria Urciuoli, Lynn T. Doglio, William R. Swindell, Rajeshwar Awatramani, Eli Sprecher, Xiaomin Bao, Eran Cohen-Barak, Caterina Missero, Johann E. Gudjonsson, Kathleen J. Green

J Clin Invest. 2022 Feb 1; 132(3): e144363. Published online 2022 Feb 1. doi: 10.1172/JCI144363

PMCID:: PMC8803337

Abstract Article PDF–3.6M

Select item 857228215.

DOK3 maintains intestinal homeostasis by suppressing JAK2/STAT3 signaling and S100a8/9 production in neutrophils

Jia Tong Loh, Koon-Guan Lee, Alison P. Lee, Joey Kay Hui Teo, Hsueh Lee Lim, Susana Soo-Yeon Kim, Andy Hee-Meng Tan, Kong-Peng Lam

Cell Death Dis. 2021 Nov; 12(11): 1054. Published online 2021 Nov 6. doi: 10.1038/s41419-021-04357-5

PMCID:: PMC8572282

Abstract Article PDF–2.9M

Select item 837506816.

S100A8/A9 is not essential for the development of inflammation and joint pathology in interleukin-1 receptor antagonist knockout mice

Irene Di Ceglie, Peter L. E. M. van Lent, Edwin J. W. Geven, Marije I. Koenders, Arjen B. Blom, Thomas Vogl, Johannes Roth, Martijn H. J. van den Bosch

Arthritis Res Ther. 2021; 23: 216. Published online 2021 Aug 19. doi: 10.1186/s13075-021-02602-y