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Items: 1 to 20 of 204

1.
Tyrosine phosphorylation of both STAT5A and STAT5B is necessary for maximal IL-2 signaling and T cell proliferation
Jian-Xin Lin, Meili Ge, Cheng-yu Liu, Ronald Holewinski, Thorkell Andresson, Zu-Xi Yu, Tesfay Gebregiorgis, Rosanne Spolski, Peng Li, Warren J. Leonard
Nat Commun. 2024; 15: 7372. Published online 2024 Aug 27. doi: 10.1038/s41467-024-50925-6
PMCID:
PMC11349758
AbstractArticlePDF–3.5M
2.
The Derlin-1-Stat5b axis maintains homeostasis of adult hippocampal neurogenesis
Naoya Murao, Taito Matsuda, Hisae Kadowaki, Yosuke Matsushita, Kousuke Tanimoto, Toyomasa Katagiri, Kinichi Nakashima, Hideki Nishitoh
EMBO Rep. 2024 Aug; 25(8): 3678–3706. Published online 2024 Jul 30. doi: 10.1038/s44319-024-00205-7
PMCID:
PMC11316036
AbstractArticlePDF–12M
3.
A lineage-specific STAT5BN642H mouse model to study NK-cell leukemia
Klara Klein, Sebastian Kollmann, Angela Hiesinger, Julia List, Jonatan Kendler, Thorsten Klampfl, Mehak Rhandawa, Jana Trifinopoulos, Barbara Maurer, Reinhard Grausenburger, Christof A. Betram, Richard Moriggl, Thomas Rülicke, Charles G. Mullighan, Agnieszka Witalisz-Siepracka, Wencke Walter, Gregor Hoermann, Veronika Sexl, Dagmar Gotthardt
Blood. 2024 Jun 13; 143(24): 2474–2489. Published online 2024 Mar 20. doi: 10.1182/blood.2023022655
PMCID:
PMC11208297
AbstractArticle
4.
Physiological significance of STAT proteins: investigations through gene disruption in vivo
D. E. Levy
Cell Mol Life Sci. 1999 Sep; 55(12): 1559–1567. doi: 10.1007/s000180050395
PMCID:
PMC11146878
AbstractPDF–86K
5.
JAK-STAT signaling maintains homeostasis in T cells and macrophages
Nikolaus Fortelny, Matthias Farlik, Victoria Fife, Anna-Dorothea Gorki, Caroline Lassnig, Barbara Maurer, Katrin Meissl, Marlies Dolezal, Laura Boccuni, Aarathy Ravi Sundar Jose Geetha, Mojoyinola Joanna Akagha, Anzhelika Karjalainen, Stephen Shoebridge, Asma Farhat, Ulrike Mann, Rohit Jain, Shweta Tikoo, Nina Zila, Wolfgang Esser-Skala, Thomas Krausgruber, Katarzyna Sitnik, Thomas Penz, Anastasiya Hladik, Tobias Suske, Sophie Zahalka, Martin Senekowitsch, Daniele Barreca, Florian Halbritter, Sabine Macho-Maschler, Wolfgang Weninger, Heidi A. Neubauer, Richard Moriggl, Sylvia Knapp, Veronika Sexl, Birgit Strobl, Thomas Decker, Mathias Müller, Christoph Bock
Nat Immunol. 2024; 25(5): 847–859. Published online 2024 Apr 24. doi: 10.1038/s41590-024-01804-1
PMCID:
PMC11065702
AbstractArticlePDF–10M
6.
Stat5 opposes the transcription factor Tox and rewires exhausted CD8+ T cells towards durable effector-like states during chronic antigen exposure
Jean-Christophe Beltra, Mohamed S. Abdel-Hakeem, Sasikanth Manne, Zhen Zhang, Hua Huang, Makoto Kurachi, Leon Su, Lora Picton, Shin Foong Ngiow, Yuki Muroyama, Valentina Casella, Yinghui J. Huang, Josephine R. Giles, Divij Mathew, Jonathan Belman, Max Klapholz, Hélène Decaluwe, Alexander C. Huang, Shelley L. Berger, K. Christopher Garcia, E. John Wherry
Immunity. Author manuscript; available in PMC 2024 Dec 12.
Published in final edited form as: Immunity. 2023 Dec 12; 56(12): 2699–2718.e11. doi: 10.1016/j.immuni.2023.11.005
PMCID:
PMC10752292
AbstractArticlePDF–3.6M
7.
Different niches for stem cells carrying the same oncogenic driver affect pathogenesis and therapy response in myeloproliferative neoplasms
Elodie Grockowiak, Claudia Korn, Justyna Rak, Veronika Lysenko, Adrien Hallou, Francesca M. Panvini, Matthew Williams, Claire Fielding, Zijian Fang, Eman Khatib-Massalha, Andrés García-García, Juan Li, Reema A. Khorshed, Sara González-Antón, E. Joanna Baxter, Anjali Kusumbe, Bridget S. Wilkins, Anna Green, Benjamin D. Simons, Claire N. Harrison, Anthony R. Green, Cristina Lo Celso, Alexandre P. A. Theocharides, Simón Méndez-Ferrer
Nat Cancer. 2023; 4(8): 1193–1209. Published online 2023 Aug 7. doi: 10.1038/s43018-023-00607-x
PMCID:
PMC10447237
AbstractArticlePDF–18M
8.
Loss of long-chain acyl-CoA synthetase 1 promotes hepatocyte death in alcohol-induced steatohepatitis
Haibo Dong, Wei Zhong, Wenliang Zhang, Liuyi Hao, Wei Guo, Ruichao Yue, Xinguo Sun, Zhaoli Sun, Ramon Bataller, Zhanxiang Zhou
Metabolism. Author manuscript; available in PMC 2023 Jun 7.
Published in final edited form as: Metabolism. 2023 Jan; 138: 155334. Published online 2022 Oct 28. doi: 10.1016/j.metabol.2022.155334
PMCID:
PMC10245388
AbstractArticlePDF–3.0M
9.
Tetramerization of STAT5 regulates monocyte differentiation and the dextran sulfate sodium-induced colitis in mice
Kelly L. Monaghan, Wen Zheng, Halima Akhter, Lei Wang, Amanda G. Ammer, Peng Li, Jian-Xin Lin, Gangqing Hu, Warren J. Leonard, Edwin C. K. Wan
Front Immunol. 2023; 14: 1117828. Published online 2023 Apr 20. doi: 10.3389/fimmu.2023.1117828
PMCID:
PMC10157487
AbstractArticlePDF–18M
10.
STAT5b is a key effector of NRG‐1/ERBB4‐mediated myocardial growth
Katri Vaparanta, Anne Jokilammi, Ilkka Paatero, Johannes A Merilahti, Juho Heliste, Karthik Amudhala Hemanthakumar, Riikka Kivelä, Kari Alitalo, Pekka Taimen, Klaus Elenius
EMBO Rep. 2023 May; 24(5): e56689. Published online 2023 Apr 3. doi: 10.15252/embr.202256689
PMCID:
PMC10157316
AbstractArticlePDF–3.6M
11.
An engineered IL-2 partial agonist promotes CD8+ T cell stemness
Fei Mo, Zhiya Yu, Peng Li, Jangsuk Oh, Rosanne Spolski, Liang Zhao, Caleb R. Glassman, Tori N. Yamamoto, Yun Chen, Filip M. Golebiowski, Dalton Hermans, Sonia S. Majri, Lora K. Picton, Wei Liao, Min Ren, Xiaoxuan Zhuang, Suman Mitra, Jian-Xin Lin, Luca Gattinoni, Jonathan D. Powell, Nicholas P. Restifo, K. Christopher Garcia, Warren J. Leonard
Nature. Author manuscript; available in PMC 2022 Jun 7.
Published in final edited form as: Nature. 2021 Sep; 597(7877): 544–548. Published online 2021 Sep 15. doi: 10.1038/s41586-021-03861-0
PMCID:
PMC9172917
AbstractArticlePDF–2.5M
12.
Constitutively Active STAT5b Feminizes Mouse Liver Gene Expression
Dana Lau-Corona, Hong Ma, Cameron Vergato, Andre Sarmento-Cabral, Mercedes del Rio-Moreno, Rhonda D Kineman, David J Waxman
Endocrinology. 2022 May; 163(5): bqac046. Published online 2022 Apr 9. doi: 10.1210/endocr/bqac046
PMCID:
PMC9070516
AbstractArticle
13.
Loss of Adipocyte STAT5 Confers Increased Depot-Specific Adiposity in Male and Female Mice That Is Not Associated With Altered Adipose Tissue Lipolysis
Allison J. Richard, Hardy Hang, Timothy D. Allerton, Peng Zhao, Tamra Mendoza, Sujoy Ghosh, Carrie M. Elks, Jacqueline M. Stephens
Front Endocrinol (Lausanne) 2022; 13: 812802. Published online 2022 Apr 7. doi: 10.3389/fendo.2022.812802
PMCID:
PMC9022209
AbstractArticlePDF–4.7M
14.
Growth Hormone-induced STAT5B Regulates Star Gene Expression Through a Cooperation With cJUN in Mouse MA-10 Leydig Cells
Pierre-Olivier Hébert-Mercier, Francis Bergeron, Nicholas M Robert, Samir Mehanovic, Kenley Joule Pierre, Raifish E Mendoza-Villarroel, Karine de Mattos, Catherine Brousseau, Jacques J Tremblay
Endocrinology. 2022 Feb; 163(2): bqab267. Published online 2021 Dec 30. doi: 10.1210/endocr/bqab267
PMCID:
PMC8765792
AbstractArticle
15.
Adipocyte STAT5 deficiency does not affect blood glucose homeostasis in obese mice
Marianna Beghini, Theresia Wagner, Andreea Corina Luca, Matthäus Metz, Doris Kaltenecker, Katrin Spirk, Martina Theresa Hackl, Johannes Haybaeck, Richard Moriggl, Alexandra Kautzky-Willer, Thomas Scherer, Clemens Fürnsinn
PLoS One. 2021; 16(11): e0260501. Published online 2021 Nov 24. doi: 10.1371/journal.pone.0260501
PMCID:
PMC8612524
AbstractArticlePDF–1.4M
16.
Satb2 regulates the development of dopaminergic neurons in the arcuate nucleus by Dlx1
Qiong Zhang, Lei Zhang, Ying Huang, Pengcheng Ma, Bingyu Mao, Yu-Qiang Ding, Ning-Ning Song
Cell Death Dis. 2021 Oct; 12(10): 879. Published online 2021 Sep 25. doi: 10.1038/s41419-021-04175-9
PMCID:
PMC8464595
AbstractArticlePDF–5.6M
17.
Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver
Najla AlOgayil, Klara Bauermeister, Jose Hector Galvez, Varun S. Venkatesh, Qinwei Kim-wee Zhuang, Matthew L. Chang, Rachel A. Davey, Jeffrey D. Zajac, Kinuyo Ida, Akihide Kamiya, Teruko Taketo, Guillaume Bourque, Anna K. Naumova
Sci Rep. 2021; 11: 13766. Published online 2021 Jul 2. doi: 10.1038/s41598-021-93216-6
Correction in:
Sci Rep. 2021; 11: 22975.
PMCID:
PMC8253761
AbstractArticlePDF–7.9M
18.
Stat5B is Required for IgE-Mediated Mast Cell Function in vitro and in vivo
Kasalina N. Kiwanuka, E. Motunrayo Kolawole, Jamie Josephine Avila Mcleod, Bianca Baker, Patrick A. Paez, Matthew P. Zellner, Tamara T. Haque, Anuya Paranjape, Kaitlyn Jackson, Sydney A. Kee, Jordan Dailey, Rebecca K. Martin, John J. Ryan
Cell Immunol. Author manuscript; available in PMC 2022 Jun 1.
Published in final edited form as: Cell Immunol. 2021 Jun; 364: 104344. Published online 2021 Mar 18. doi: 10.1016/j.cellimm.2021.104344
PMCID:
PMC8104437
AbstractArticlePDF–1.0M
19.
STAT5 Regulation of Sex-Dependent Hepatic CpG Methylation at Distal Regulatory Elements Mapping to Sex-Biased Genes
Pengying Hao, David J. Waxman
Mol Cell Biol. 2021 Feb; 41(2): e00166-20. Prepublished online 2020 Nov 16. Published online 2021 Jan 25. doi: 10.1128/MCB.00166-20
PMCID:
PMC8093489
AbstractArticlePDF–4.8M
20.
Divergent Role for STAT5 in the Adaptive Responses of Natural Killer Cells
Gabriela M. Wiedemann, Simon Grassmann, Colleen M. Lau, Moritz Rapp, Alejandro V. Villarino, Christin Friedrich, Georg Gasteiger, John J. O’Shea, Joseph C. Sun
Cell Rep. Author manuscript; available in PMC 2020 Dec 30.
Published in final edited form as: Cell Rep. 2020 Dec 15; 33(11): 108498. doi: 10.1016/j.celrep.2020.108498
PMCID:
PMC7773031
AbstractArticlePDF–1.7M

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