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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 98491112.

USP9X-mediated NRP1 deubiquitination promotes liver fibrosis by activating hepatic stellate cells

Jinqiu Zhao, Jie Bai, Fengling Peng, Chan Qiu, Yongguo Li, Li Zhong

Cell Death Dis. 2023 Jan; 14(1): 40. Published online 2023 Jan 19. doi: 10.1038/s41419-022-05527-9

PMCID:: PMC9849111

Abstract Article PDF–4.2M

Select item 96941043.

Requirement of hepatic pyruvate carboxylase during fasting, high fat, and ketogenic diet

Ebru S. Selen, Susana Rodriguez, Kyle S. Cavagnini, Han-Byeol Kim, Chan Hyun Na, Michael J. Wolfgang

J Biol Chem. 2022 Dec; 298(12): 102648. Published online 2022 Oct 28. doi: 10.1016/j.jbc.2022.102648

PMCID:: PMC9694104

Abstract Article PDF–2.2M

Select item 74159914.

BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING)

Kou Motani, Hidetaka Kosako

J Biol Chem. 2020 Aug 7; 295(32): 11174–11183. Published online 2020 Jun 17. doi: 10.1074/jbc.RA120.014323

PMCID:: PMC7415991

Abstract Article PDF–2.0M

Select item 72950335.

Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant

Meagan A. Quinlan, Matthew J. Robson, Ran Ye, Kristie L. Rose, Kevin L. Schey, Randy D. Blakely

Front Mol Neurosci. 2020; 13: 89. Published online 2020 Jun 8. doi: 10.3389/fnmol.2020.00089

PMCID:: PMC7295033

Abstract Article PDF–2.7M

Select item 70572586.

Glycogen Dynamics Drives Lipid Droplet Biogenesis during Brown Adipocyte Differentiation

Alicia Mayeuf-Louchart, Steve Lancel, Yasmine Sebti, Benoit Pourcet, Anne Loyens, Stéphane Delhaye, Christian Duhem, Justine Beauchamp, Lise Ferri, Quentin Thorel, Alexis Boulinguiez, Mathilde Zecchin, Julie Dubois-Chevalier, Jérôme Eeckhoute, Logan T. Vaughn, Peter J. Roach, Christian Dani, Bartholomew A. Pederson, Stéphane D. Vincent, Bart Staels, Hélène Duez

Cell Rep. 2019 Nov 5; 29(6): 1410–1418.e6. Published online 2019 Nov 5. doi: 10.1016/j.celrep.2019.09.073

PMCID:: PMC7057258

Abstract Article

Select item 66291767.

Loss of Super-Enhancer-Regulated circRNA Nfix Induces Cardiac Regeneration After Myocardial Infarction in Adult Mice

Senlin Huang, Xinzhong Li, Hao Zheng, Xiaoyun Si, Bing Li, Guoquan Wei, Chuling Li, Yijin Chen, Yanmei Chen, Wangjun Liao, Yulin Liao, Jianping Bin

Circulation. 2019 Jun 18; 139(25): 2857–2876. Published online 2019 Apr 5. doi: 10.1161/CIRCULATIONAHA.118.038361

PMCID:: PMC6629176

Abstract Article PDF–5.1M

Select item 65859688.

Pyruvate carboxylase mediated anaplerosis promotes antioxidant capacity by sustaining TCA cycle and redox metabolism in liver

David A. Cappel, Stanisław Deja, João A.G. Duarte, Blanka Kucejova, Melissa Iñigo, Justin A. Fletcher, Xiaorong Fu, Eric D. Berglund, Tiemin Liu, Joel K. Elmquist, Suntrea Hammer, Prashant Mishra, Jeffrey D. Browning, Shawn C. Burgess

Cell Metab. Author manuscript; available in PMC 2020 Jun 4.

Published in final edited form as: Cell Metab. 2019 Jun 4; 29(6): 1291–1305.e8. Published online 2019 Apr 18. doi: 10.1016/j.cmet.2019.03.014

PMCID:: PMC6585968

Abstract Article PDF–1.3M

Select item 65547239.

Interactome Analysis Reveals Regulator of G Protein Signaling 14 (RGS14) is a Novel Calcium/Calmodulin (Ca²⁺/CaM) and CaM Kinase II (CaMKII) Binding Partner

Paul R. Evans, Kyle J. Gerber, Eric B. Dammer, Duc M. Duong, Devrishi Goswami, Daniel J. Lustberg, Juan Zou, Jenny J. Yang, Serena M. Dudek, Patrick R. Griffin, Nicholas T. Seyfried, John R. Hepler

J Proteome Res. Author manuscript; available in PMC 2019 Jun 7.

Published in final edited form as: J Proteome Res. 2018 Apr 6; 17(4): 1700–1711. Published online 2018 Mar 20. doi: 10.1021/acs.jproteome.8b00027

PMCID:: PMC6554723

Abstract Article PDF–2.0M

Select item 535051210.

CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs

Désirée Schatton, David Pla-Martin, Marie-Charlotte Marx, Henriette Hansen, Arnaud Mourier, Ivan Nemazanyy, Alberto Pessia, Peter Zentis, Teresa Corona, Vangelis Kondylis, Esther Barth, Astrid C. Schauss, Vidya Velagapudi, Elena I. Rugarli

J Cell Biol. 2017 Mar 6; 216(3): 675–693. doi: 10.1083/jcb.201607019

PMCID:: PMC5350512

Abstract Article PDF–3.2M

Select item 533761811.

Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development

Vinay Bulusu, Nicole Prior, Marteinn T. Snaebjornsson, Andreas Kuehne, Katharina F. Sonnen, Jana Kress, Frank Stein, Carsten Schultz, Uwe Sauer, Alexander Aulehla

Dev Cell. 2017 Feb 27; 40(4): 331–341.e4. doi: 10.1016/j.devcel.2017.01.015

PMCID:: PMC5337618

Abstract Article

Select item 529582112.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 513335213.

Hepatic Glucocorticoid Receptor Plays a Greater Role Than Adipose GR in Metabolic Syndrome Despite Renal Compensation

Sandip K. Bose, Irina Hutson, Charles A. Harris

Endocrinology. 2016 Dec; 157(12): 4943–4960. Published online 2016 Oct 18. doi: 10.1210/en.2016-1615

PMCID:: PMC5133352

Abstract Article

Select item 504520014.

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury

Yong Wu, Fan-Yan Wei, Layla Kawarada, Takeo Suzuki, Kimi Araki, Yoshihiro Komohara, Atsushi Fujimura, Taku Kaitsuka, Motohiro Takeya, Yuichi Oike, Tsutomu Suzuki, Kazuhito Tomizawa

PLoS Genet. 2016 Sep; 12(9): e1006355. Published online 2016 Sep 30. doi: 10.1371/journal.pgen.1006355

PMCID:: PMC5045200

Abstract Article PDF–2.9M

Select item 494642715.

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series

Caitlyn E. Bowman, Liang Zhao, Thomas Hartung, Michael J. Wolfgang

Mol Cell Biol. 2016 Aug 1; 36(15): 2089–2104. Prepublished online 2016 May 23. Published online 2016 Jul 14. doi: 10.1128/MCB.00166-16

PMCID:: PMC4946427

Abstract Article PDF–3.4M

Select item 489776316.

The MDM2–p53–pyruvate carboxylase signalling axis couples mitochondrial metabolism to glucose-stimulated insulin secretion in pancreatic β-cells

Xiaomu Li, Kenneth K. Y. Cheng, Zhuohao Liu, Jin-Kui Yang, Baile Wang, Xue Jiang, Yawen Zhou, Philip Hallenborg, Ruby L. C. Hoo, Karen S. L. Lam, Yasuhiro Ikeda, Xin Gao, Aimin Xu

Nat Commun. 2016; 7: 11740. Published online 2016 Jun 6. doi: 10.1038/ncomms11740

PMCID:: PMC4897763

Abstract Article PDF–1.7M

Select item 486233217.

Regulation of podocalyxin trafficking by Rab small GTPases in 2D and 3D epithelial cell cultures

Paulina S. Mrozowska, Mitsunori Fukuda

J Cell Biol. 2016 May 9; 213(3): 355–369. doi: 10.1083/jcb.201512024

PMCID:: PMC4862332

Abstract Article PDF–3.3M

Select item 431944118.

Pyruvate carboxylase is critical for non–small-cell lung cancer proliferation

Katherine Sellers, Matthew P. Fox, Michael Bousamra, II, Stephen P. Slone, Richard M. Higashi, Donald M. Miller, Yali Wang, Jun Yan, Mariia O. Yuneva, Rahul Deshpande, Andrew N. Lane, Teresa W.-M. Fan

J Clin Invest. 2015 Feb 2; 125(2): 687–698. Published online 2015 Jan 20. doi: 10.1172/JCI72873

PMCID:: PMC4319441

Abstract Article PDF–2.3M

Select item 430400319.

The Peroxisome Proliferator-activated Receptor-γ Regulates Murine Pyruvate Carboxylase Gene Expression in Vivo and in Vitro

Sarawut Jitrapakdee, Marc Slawik, Gema Medina-Gomez, Mark Campbell, John C. Wallace, Jaswinder K. Sethi, Stephen O’Rahilly, Antonio J. Vidal-Puig

J Biol Chem. Author manuscript; available in PMC 2015 Jan 23.

Published in final edited form as: J Biol Chem. 2005 Jul 22; 280(29): 27466–27476. Published online 2005 May 25. doi: 10.1074/jbc.M503836200

PMCID:: PMC4304003

Abstract Article PDF–1.7M

Select item 396495520.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

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