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Items: 1 to 20 of 47

1.
Maternal DHA intake in mice increased DHA metabolites in the pup brain and ameliorated MeHg-induced behavioral disorder
Ami Oguro, Taichi Fujiyama, Yasuhiro Ishihara, Chisato Kataoka, Megumi Yamamoto, Komyo Eto, Yoshihiro Komohara, Susumu Imaoka, Toshihide Sakuragi, Mayumi Tsuji, Eiji Shibata, Yaichiro Kotake, Takeshi Yamazaki
J Lipid Res. 2023 Nov; 64(11): 100458. Published online 2023 Oct 12. doi: 10.1016/j.jlr.2023.100458
PMCID:
PMC10656226
AbstractArticlePDF–2.6M
2.
High-fat diet induces fibrosis in mice lacking CYP2A5 and PPARα: a new model for steatohepatitis-associated fibrosis
Xue Chen, George K. Acquaah-Mensah, Krista L. Denning, Jonathan M. Peterson, Kesheng Wang, James Denvir, Feng Hong, Arthur I. Cederbaum, Yongke Lu
Am J Physiol Gastrointest Liver Physiol. 2020 Nov 1; 319(5): G626–G635. Published online 2020 Sep 2. doi: 10.1152/ajpgi.00213.2020
PMCID:
PMC8087345
AbstractArticle
3.
Highly homologous mouse Cyp2a4 and Cyp2a5 genes are differentially expressed in the liver and both express long non-coding antisense RNAs
Alexandra N. Nail, Brett T. Spear, Martha L. Peterson
Gene. Author manuscript; available in PMC 2022 Jan 30.
Published in final edited form as: Gene. 2021 Jan 30; 767: 145162. Published online 2020 Sep 25. doi: 10.1016/j.gene.2020.145162
PMCID:
PMC7722232
AbstractArticlePDF–1.7M
4.
Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine-and cotinine-enhanced alcoholic fatty liver in mice
Xue Chen, Kesheng Wang, Arthur I. Cederbaum, Yongke Lu
Biochem Biophys Res Commun. Author manuscript; available in PMC 2020 Apr 23.
Published in final edited form as: Biochem Biophys Res Commun. 2019 Apr 23; 512(1): 119–124. Published online 2019 Mar 12. doi: 10.1016/j.bbrc.2019.03.021
PMCID:
PMC6433518
AbstractArticlePDF–2.0M
5.
Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5
Xue Chen, Emmanuel Owoseni, Julia salamat, Arthur I. Cederbaum, Yongke Lu
Arch Biochem Biophys. Author manuscript; available in PMC 2019 Nov 1.
Published in final edited form as: Arch Biochem Biophys. 2018 Nov 1; 657: 65–73. Published online 2018 Sep 15. doi: 10.1016/j.abb.2018.09.012
PMCID:
PMC6177319
AbstractArticlePDF–819K
6.
Zinc Fingers and Homeoboxes 2 (Zhx2) Regulates Sexually Dimorphic Cyp Gene Expression in the Adult Mouse Liver
Kate Townsend Creasy, Jieyun Jiang, Hui Ren, Martha L. Peterson, Brett T. Spear
Gene Expr. 2016; 17(1): 7–17. Published online 2016 May 17. doi: 10.3727/105221616X691712
PMCID:
PMC5518317
AbstractArticlePDF–8.5M
7.
Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver
Katia S. Poça, Thiago E. M. Parente, Lucas F. Chagas, Bruna S. Leal, Hellen S. Leal, Francisco J. R. Paumgartten, Ana C. A. X. De-Oliveira
BMC Res Notes. 2017; 10: 125. Published online 2017 Mar 15. doi: 10.1186/s13104-017-2435-x
PMCID:
PMC5353797
AbstractArticlePDF–1.4M
8.
Alcoholic fatty liver is enhanced in CYP2A5 knockout mice: the role of the PPARα-FGF21 axis
Xue Chen, Stephen C. Ward, Arthur I. Cederbaum, Huabao Xiong, Yongke Lu
Toxicology. Author manuscript; available in PMC 2018 Mar 15.
Published in final edited form as: Toxicology. 2017 Mar 15; 379: 12–21. Published online 2017 Jan 25. doi: 10.1016/j.tox.2017.01.016
PMCID:
PMC5319905
AbstractArticlePDF–1.0M
9.
Genomic Landscape of Experimental Bladder Cancer in Rodents and Its Application to Human Bladder Cancer: Gene Amplification and Potential Overexpression of Cyp2a5/CYP2A6 Are Associated with the Invasive Phenotype
Kazuhiro Kanemoto, Katsuhiro Fukuta, Noriyasu Kawai, Keiichi Tozawa, Masako Ochiai, Koji Okamoto, Sumiko Ohnami, Hiromi Sakamoto, Teruhiko Yoshida, Yae Kanai, Masaru Katoh, Takahiro Yasui, Kenjiro Kohri, Tadao Kakizoe, Hitoshi Nakagama
PLoS One. 2016; 11(11): e0167374. Published online 2016 Nov 30. doi: 10.1371/journal.pone.0167374
PMCID:
PMC5130269
AbstractArticlePDF–3.7M
10.
Resveratrol improves health and survival of mice on a high-calorie diet
Joseph A. Baur, Kevin J. Pearson, Nathan L. Price, Hamish A. Jamieson, Carles Lerin, Avash Kalra, Vinayakumar V. Prabhu, Joanne S. Allard, Guillermo Lopez-Lluch, Kaitlyn Lewis, Paul J. Pistell, Suresh Poosala, Kevin G. Becker, Olivier Boss, Dana Gwinn, Mingyi Wang, Sharan Ramaswamy, Kenneth W. Fishbein, Richard G. Spencer, Edward G. Lakatta, David Le Couteur, Reuben J. Shaw, Placido Navas, Pere Puigserver, Donald K. Ingram, Rafael de Cabo, David A. Sinclair
Nature. Author manuscript; available in PMC 2016 Aug 18.
Published in final edited form as: Nature. 2006 Nov 16; 444(7117): 337–342. Published online 2006 Nov 1. doi: 10.1038/nature05354
PMCID:
PMC4990206
AbstractArticlePDF–598K
11.
The role of CYP2A5 in liver injury and fibrosis: chemical-specific difference
Feng Hong, Chuanping Si, Pengfei Gao, Arthur I. Cederbaum, Huabao Xiong, Yongke Lu
Naunyn Schmiedebergs Arch Pharmacol. Author manuscript; available in PMC 2017 Jan 1.
Published in final edited form as: Naunyn Schmiedebergs Arch Pharmacol. 2016 Jan; 389(1): 33–43. Published online 2015 Sep 12. doi: 10.1007/s00210-015-1172-8
PMCID:
PMC4703559
AbstractArticlePDF–3.6M
12.
Absence of cytochrome P450 2A5 enhances alcohol-induced liver injury in mice
Feng Hong, Xiyu Liu, Stephen Ward, Huabao Xiong, Arthur I. Cederbaum, Yongke Lu
Dig Liver Dis. Author manuscript; available in PMC 2016 Jun 1.
Published in final edited form as: Dig Liver Dis. 2015 Jun; 47(6): 470–477. Published online 2015 Mar 6. doi: 10.1016/j.dld.2015.02.012
PMCID:
PMC4442740
AbstractArticlePDF–2.8M
13.
Modulation of Cytochrome P450 2A5 Activity by Lipopolysaccharide: Low-Dose Effects and Non-Monotonic Dose-Response Relationship
Ana C. A. X. De-Oliveira, Kátia S. Poça, Paulo R. R. Totino, Francisco J. R. Paumgartten
PLoS One. 2015; 10(1): e0117842. Published online 2015 Jan 30. doi: 10.1371/journal.pone.0117842
PMCID:
PMC4311977
AbstractArticlePDF–761K
14.
Identification and quantification of the basal and inducible Nrf2-dependent proteomes in mouse liver: Biochemical, pharmacological and toxicological implications
Joanne Walsh, Rosalind E. Jenkins, Michael Wong, Adedamola Olayanju, Helen Powell, Ian Copple, Paul M. O’Neill, Christopher E.P. Goldring, Neil R. Kitteringham, B. Kevin Park
J Proteomics. 2014 Aug 28; 108(100): 171–187. doi: 10.1016/j.jprot.2014.05.007
PMCID:
PMC4115266
AbstractArticlePDF–859K
15.
Possible involvement of nuclear factor erythroid 2-related factor 2 in the gene expression of Cyp2b10 and Cyp2a5
Takashi Ashino, Haruyo Ohkubo-Morita, Masayuki Yamamoto, Takemi Yoshida, Satoshi Numazawa
Redox Biol. 2014; 2: 284–288. Published online 2014 Jan 10. doi: 10.1016/j.redox.2013.12.025
PMCID:
PMC3909825
AbstractArticlePDF–359K
16.
Essential Role of the Cytochrome P450 Enzyme CYP2A5 in Olfactory Mucosal Toxicity of Naphthalene
Jinping Hu, Li Sheng, Lei Li, Xin Zhou, Fang Xie, Jaime D’Agostino, Yan Li, Xinxin Ding
Drug Metab Dispos. 2014 Jan; 42(1): 23–27. Published online 2014 Jan. doi: 10.1124/dmd.113.054429
PMCID:
PMC3876791
AbstractArticlePDF–985K
17.
Role of CYP2A13 in the bioactivation and lung tumorigenicity of the tobacco-specific lung procarcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone: in vivo studies using a CYP2A13-humanized mouse model
Vandana Megaraj, Xin Zhou, Fang Xie, Zhihua Liu, Weizhu Yang, Xinxin Ding
Carcinogenesis. 2014 Jan; 35(1): 131–137. Published online 2013 Aug 28. doi: 10.1093/carcin/bgt269
PMCID:
PMC3871935
AbstractArticlePDF–759K
18.
Impact of Nicotine Metabolism on Nicotine’s Pharmacological Effects and Behavioral Responses: Insights from a Cyp2a(4/5)bgs-Null Mouse
Lei Li, Kunzhi Jia, Xin Zhou, Sarah E. McCallum, Lindsay B. Hough, Xinxin Ding
J Pharmacol Exp Ther. 2013 Dec; 347(3): 746–754. Published online 2013 Dec. doi: 10.1124/jpet.113.208256
PMCID:
PMC3836308
AbstractArticlePDF–915K
19.
Experimental nonalcoholic fatty liver disease in mice leads to cytochrome p450 2a5 upregulation through nuclear factor erythroid 2-like 2 translocation
Yizhe Cui, Qiuju Wang, Xiaochong Li, Xiuying Zhang
Redox Biol. 2013; 1(1): 433–440. Published online 2013 Aug 24. doi: 10.1016/j.redox.2013.08.003
PMCID:
PMC3814957
AbstractArticlePDF–1.2M
20.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M

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