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Select item 109320351.

Deletion of Sarcolemmal Membrane-Associated Protein Isoform 3 (SLMAP3) in Cardiac Progenitors Delays Embryonic Growth of Myocardium without Affecting Hippo Pathway

Taha Rehmani, Ana Paula Dias, Marsel Kamal, Maysoon Salih, Balwant S. Tuana

Int J Mol Sci. 2024 Mar; 25(5): 2888. Published online 2024 Mar 1. doi: 10.3390/ijms25052888

PMCID:: PMC10932035

Abstract Article PDF–4.4M

Select item 103275772.

Protein phosphatase 2A propels follicular T helper cell development in lupus

Yu Jiang, Xuexiao Jin, Zhexu Chi, Yadan Bai, Kalpana Manthiram, Pamela Mudd, Kaixiang Zhu, Lie Wang, Pamela L. Schwartzberg, Yongmei Han, Xiang Gao, Linrong Lu, Qin Xu

J Autoimmun. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: J Autoimmun. 2023 Apr; 136: 103028. Published online 2023 Mar 29. doi: 10.1016/j.jaut.2023.103028

PMCID:: PMC10327577

Abstract Article PDF–2.6M

Select item 98413333.

The MASTL/PP2A cell cycle kinase‐phosphatase module restrains PI3K‐Akt activity in an mTORC1‐dependent manner

Belén Sanz‐Castillo, Begoña Hurtado, Diana Vara‐Ciruelos, Aicha El Bakkali, Dario Hermida, Beatriz Salvador‐Barbero, Diego Martínez‐Alonso, José González‐Martínez, Clara Santiveri, Ramón Campos‐Olivas, Pilar Ximénez‐Embún, Javier Muñoz, Mónica Álvarez‐Fernández, Marcos Malumbres

EMBO J. 2023 Jan; 42(2): e110833. Published online 2022 Nov 10. doi: 10.15252/embj.2022110833

PMCID:: PMC9841333

Abstract Article PDF–2.7M

Select item 97006004.

ATM phosphorylates PP2A subunit A resulting in nuclear export and spatiotemporal regulation of the DNA damage response

Amrita Sule, Sarah E. Golding, Syed F. Ahmad, James Watson, Mostafa H. Ahmed, Glen E. Kellogg, Tytus Bernas, Sean Koebley, Jason C. Reed, Lawrence F. Povirk, Kristoffer Valerie

Cell Mol Life Sci. 2022; 79(12): 603. Published online 2022 Nov 24. doi: 10.1007/s00018-022-04550-5

PMCID:: PMC9700600

Abstract Article PDF–3.6M

Select item 96845575.

Manipulating PP2Acα-ASK-JNK signaling to favor apoptotic over necroptotic hepatocyte fate reduces the extent of necrosis and fibrosis upon acute liver injury

Ke Lu, Si-Yu Shen, Ou-Yang Luo, Yue Lu, Tian-Shu Shi, Jing Wu, Qi Cheng, Hua-Jian Teng, Di Chen, Xiang Lu, Chao-Jun Li, Qing Jiang, Lei Fang, Bin Xue

Cell Death Dis. 2022 Nov; 13(11): 985. Published online 2022 Nov 22. doi: 10.1038/s41419-022-05353-z

PMCID:: PMC9684557

Abstract Article PDF–8.0M

Select item 94215846.

Liver PP2A-Cα Protects From Parenteral Nutrition-associated Hepatic Steatosis

Gulisudumu Maitiabula, Feng Tian, Peng Wang, Li Zhang, Xuejin Gao, Songlin Wan, Haifeng Sun, Jianbo Yang, Yupeng Zhang, Tingting Gao, Bin Xue, Chaojun Li, Jieshou Li, Xinying Wang

Cell Mol Gastroenterol Hepatol. 2022; 14(3): 669–692. Published online 2022 May 26. doi: 10.1016/j.jcmgh.2022.05.008

PMCID:: PMC9421584

Abstract Article PDF–8.4M

Select item 91010927.

Protein Phosphatase 2A Improves Cardiac Functional Response to Ischemia and Sepsis

Ulrich Gergs, Tina Jahn, Nico Schulz, Claudia Großmann, Uwe Rueckschloss, Uta Demus, Igor B. Buchwalow, Joachim Neumann

Int J Mol Sci. 2022 May; 23(9): 4688. Published online 2022 Apr 23. doi: 10.3390/ijms23094688

PMCID:: PMC9101092

Abstract Article PDF–4.3M

Select item 86240688.

Overexpression of Heat Shock Protein 70 Improves Cardiac Remodeling and Survival in Protein Phosphatase 2A-Expressing Transgenic Mice with Chronic Heart Failure

Somy Yoon, Ulrich Gergs, Julie R. McMullen, Gwang Hyeon Eom

Cells. 2021 Nov; 10(11): 3180. Published online 2021 Nov 15. doi: 10.3390/cells10113180

PMCID:: PMC8624068

Abstract Article PDF–2.2M

Select item 85678409.

The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer

Stephin J. Vervoort, Sarah A. Welsh, Jennifer R. Devlin, Elisa Barbieri, Deborah A. Knight, Sarah Offley, Stefan Bjelosevic, Matteo Costacurta, Izabela Todorovski, Conor J. Kearney, Jarrod J. Sandow, Zheng Fan, Benjamin Blyth, Victoria McLeod, Joseph H.A. Vissers, Karolina Pavic, Ben P. Martin, Gareth Gregory, Elena Demosthenous, Magnus Zethoven, Isabella Y. Kong, Edwin D. Hawkins, Simon J. Hogg, Madison J. Kelly, Andrea Newbold, Kaylene J. Simpson, Otto Kauko, Kieran F. Harvey, Michael Ohlmeyer, Jukka Westermarck, Nathanael Gray, Alessandro Gardini, Ricky W. Johnstone

Cell. Author manuscript; available in PMC 2022 Jun 10.

Published in final edited form as: Cell. 2021 Jun 10; 184(12): 3143–3162.e32. Published online 2021 May 17. doi: 10.1016/j.cell.2021.04.022

PMCID:: PMC8567840

Abstract Article PDF–2.8M

Select item 844897310.

Protein Phosphatase 2A Activation via ApoER2 in Trophoblasts Drives Preeclampsia in a Mouse Model of the Antiphospholipid Syndrome

Haiyan Chu, Anastasia Sacharidou, An Nguyen, Chun Li, Ken L. Chambliss, Jane E. Salmon, Yu-Min Shen, Julie Lo, Gustavo W. Leone, Joachim Herz, David Y. Hui, Denise K. Marciano, Vikki M. Abrahams, Bryony V. Natale, Alina P. Montalbano, Xue Xiao, Lin Xu, David R. Natale, Philip W. Shaul, Chieko Mineo

Circ Res. Author manuscript; available in PMC 2022 Sep 17.

Published in final edited form as: Circ Res. 2021 Sep 17; 129(7): 735–750. Published online 2021 Aug 18. doi: 10.1161/CIRCRESAHA.120.318941

PMCID:: PMC8448973

Abstract Article PDF–2.6M

Select item 831323911.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 817780512.

Tumor‐associated macrophages promote the metastasis and growth of non‐small‐cell lung cancer cells through NF‐κB/PP2Ac‐positive feedback loop

Zhan‐Wen Liang, Xin‐Xin Ge, Meng‐Dan Xu, Hualong Qin, Meng‐Yao Wu, Meng Shen, Yan Zhang, Xiao‐Meng Liu, Kai Chen, Wei Li, Weiming Duan, Songbing Qin

Cancer Sci. 2021 Jun; 112(6): 2140–2157. Published online 2021 May 1. doi: 10.1111/cas.14863

PMCID:: PMC8177805

Abstract Article PDF–3.7M

Select item 817253413.

PP2A in LepR+ mesenchymal stem cells contributes to embryonic and postnatal endochondral ossification through Runx2 dephosphorylation

Yu-Ting Yen, May Chien, Pei-Yi Wu, Shih-Chieh Hung

Commun Biol. 2021; 4: 658. Published online 2021 Jun 2. doi: 10.1038/s42003-021-02175-1

PMCID:: PMC8172534

Abstract Article PDF–5.1M

Select item 793877014.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 746705915.

Inhibition of Protein Phosphatase-2A with LB-100 Enhances Antitumor Immunity Against Glioblastoma

Dominic Maggio, Winson S. Ho, Rebecca Breese, Stuart Walbridge, Herui Wang, Jing Cui, John D. Heiss, Mark R. Gilbert, John S. Kovach, Rongze O. Lu, Zhengping Zhuang

J Neurooncol. Author manuscript; available in PMC 2020 Sep 2.

Published in final edited form as: J Neurooncol. 2020 Jun; 148(2): 231–244. Published online 2020 Apr 27. doi: 10.1007/s11060-020-03517-5