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Select item 113716321.

Optogenetic stimulation of mouse Hoxb8 microglia in specific regions of the brain induces anxiety, grooming, or both

Naveen Nagarajan, Mario R. Capecchi

Mol Psychiatry. 2024; 29(6): 1726–1740. Published online 2023 Apr 10. doi: 10.1038/s41380-023-02019-w

PMCID:: PMC11371632

Abstract Article PDF–4.7M

Select item 104371232.

A new Hoxb8FlpO mouse line for intersectional approaches to dissect developmentally defined adult sensorimotor circuits

Manon Bohic, Aman Upadhyay, Jaclyn T. Eisdorfer, Jessica Keating, Rhiana C. Simon, Brandy A. Briones, Chloe Azadegan, Hannah D. Nacht, Olisemeka Oputa, Alana M. Martinez, Bridget N. Bethell, Mark A. Gradwell, Peter Romanienko, Matt S. Ramer, Garret D. Stuber, Victoria E. Abraira

Front Mol Neurosci. 2023; 16: 1176823. Published online 2023 Aug 1. doi: 10.3389/fnmol.2023.1176823

PMCID:: PMC10437123

Abstract Article PDF–3.5M

Select item 103904923.

Three-dimensional molecular architecture of mouse organogenesis

Fangfang Qu, Wenjia Li, Jian Xu, Ruifang Zhang, Jincan Ke, Xiaodie Ren, Xiaogao Meng, Lexin Qin, Jingna Zhang, Fangru Lu, Xin Zhou, Xi Luo, Zhen Zhang, Minhan Wang, Guangming Wu, Duanqing Pei, Jiekai Chen, Guizhong Cui, Shengbao Suo, Guangdun Peng

Nat Commun. 2023; 14: 4599. Published online 2023 Jul 31. doi: 10.1038/s41467-023-40155-7

PMCID:: PMC10390492

Abstract Article PDF–13M

Select item 91245724.

Defining the Hoxb8 cell lineage during murine definitive hematopoiesis

Donn A. Van Deren, Shrutokirti De, Ben Xu, Kayla M. Eschenbacher, Shuhua Zhang, Mario R. Capecchi

Development. 2022 Apr 15; 149(8): dev200200. Published online 2022 Apr 22. doi: 10.1242/dev.200200

PMCID:: PMC9124572

Abstract Article

Select item 85288195.

Mice lacking DYRK2 exhibit congenital malformations with lung hypoplasia and altered Foxf1 expression gradient

Satomi Yogosawa, Makiko Ohkido, Takuro Horii, Yasumasa Okazaki, Jun Nakayama, Saishu Yoshida, Shinya Toyokuni, Izuho Hatada, Mitsuru Morimoto, Kiyotsugu Yoshida

Commun Biol. 2021; 4: 1204. Published online 2021 Oct 20. doi: 10.1038/s42003-021-02734-6

PMCID:: PMC8528819

Abstract Article PDF–3.6M

Select item 82923226.

High-depth spatial transcriptome analysis by photo-isolation chemistry

Mizuki Honda, Shinya Oki, Ryuichi Kimura, Akihito Harada, Kazumitsu Maehara, Kaori Tanaka, Chikara Meno, Yasuyuki Ohkawa

Nat Commun. 2021; 12: 4416. Published online 2021 Jul 20. doi: 10.1038/s41467-021-24691-8

PMCID:: PMC8292322

Abstract Article PDF–2.1M

Select item 77046667.

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster

Yoshiki Higashijima, Nao Nagai, Masamichi Yamamoto, Taro Kitazawa, Yumiko K. Kawamura, Akashi Taguchi, Natsuko Nakada, Masaomi Nangaku, Tetsushi Furukawa, Hiroyuki Aburatani, Hiroki Kurihara, Youichiro Wada, Yasuharu Kanki

Commun Biol. 2020; 3: 725. Published online 2020 Nov 30. doi: 10.1038/s42003-020-01456-5

PMCID:: PMC7704666

Abstract Article PDF–1.3M

Select item 72599518.

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates

Tempei Sato, Kensuke Kataoka, Yoshiaki Ito, Shigetoshi Yokoyama, Masafumi Inui, Masaki Mori, Satoru Takahashi, Keiichi Akita, Shuji Takada, Hiroe Ueno-Kudoh, Hiroshi Asahara

eLife. 2020; 9: e53608. Published online 2020 May 29. doi: 10.7554/eLife.53608

PMCID:: PMC7259951

Abstract Article PDF–5.5M

Select item 68769919.

A Microglia Sublineage Protects from Sex-Linked Anxiety Symptoms and Obsessive Compulsion

Dimitri Tränkner, Anne Boulet, Erik Peden, Richard Focht, Donn Van Deren, Mario Capecchi

Cell Rep. Author manuscript; available in PMC 2019 Nov 25.

Published in final edited form as: Cell Rep. 2019 Oct 22; 29(4): 791–799.e3. doi: 10.1016/j.celrep.2019.09.045

PMCID:: PMC6876991

Abstract Article PDF–1.6M

Select item 676057210.

Upregulated expression of HOXB7 in intrahepatic cholangiocarcinoma is associated with tumor cell metastasis and poor prognosis

Longfei Dai, Wendi Hu, Zhenjie Yang, Diyu Chen, Bin He, Yunhao Chen, Lin Zhou, Haiyang Xie, Jian Wu, Shusen Zheng

Lab Invest. 2019; 99(6): 736–748. Published online 2019 Jan 21. doi: 10.1038/s41374-018-0150-4

PMCID:: PMC6760572

Abstract Article PDF–3.8M

Select item 670541211.

Hoxb8 Intersection Defines a Role for Lmx1b in Excitatory Dorsal Horn Neuron Development, Spinofugal Connectivity, and Nociception

Nora E. Szabo, Ronan V. da Silva, Susana G. Sotocinal, Hanns Ulrich Zeilhofer, Jeffrey S. Mogil, Artur Kania

J Neurosci. 2015 Apr 1; 35(13): 5233–5246. doi: 10.1523/JNEUROSCI.4690-14.2015

PMCID:: PMC6705412

Abstract Article PDF–5.3M

Select item 646668712.

Abnormal level of CUL4B-mediated histone H2A ubiquitination causes disruptive HOX gene expression

Ye Lin, Juan Yu, Jianxin Wu, Shan Wang, Ting Zhang

Epigenetics Chromatin. 2019; 12: 22. Published online 2019 Apr 16. doi: 10.1186/s13072-019-0268-7

PMCID:: PMC6466687

Abstract Article PDF–3.0M

Select item 638138813.

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System

Fatima Memic, Viktoria Knoflach, Khomgrit Morarach, Rebecca Sadler, Catia Laranjeira, Jens Hjerling-Leffler, Erik Sundström, Vassilis Pachnis, Ulrika Marklund

Gastroenterology. 2018 Feb; 154(3): 624–636. doi: 10.1053/j.gastro.2017.10.005

PMCID:: PMC6381388

Abstract Article

Select item 634842114.

HoxB8 neutrophils replicate Fcγ receptor and integrin‐induced neutrophil signaling and functions

Julia Y. Chu, Barry McCormick, Greta Mazelyte, Melina Michael, Sonja Vermeren

J Leukoc Biol. 2019 Jan; 105(1): 93–100. Published online 2018 Sep 13. doi: 10.1002/JLB.1AB0618-232R

PMCID:: PMC6348421

Abstract Article PDF–1.3M

Select item 632832515.

Spatiotemporal loss of NF1 in Schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification by the Hippo pathway

Zhiguo Chen, Juan Mo, Jean-Philippe Brosseau, Tracey Shipman, Yong Wang, Chung-Ping Liao, Jonathan M. Cooper, Robert J. Allaway, Sara J.C. Gosline, Justin Guinney, Thomas J. Carroll, Lu Q. Le

Cancer Discov. Author manuscript; available in PMC 2020 Jan 1.

Published in final edited form as: Cancer Discov. 2019 Jan; 9(1): 114–129. Published online 2018 Oct 22. doi: 10.1158/2159-8290.CD-18-0151

PMCID:: PMC6328325

Abstract Article PDF–1.7M

Select item 619134416.

FOXF1 Transcription Factor Promotes Lung Morphogenesis by Inducing Cellular Proliferation in Fetal Lung Mesenchyme

Vladimir Ustiyan, Craig Bolte, Yufang Zhang, Lu Han, Yan Xu, Katherine E. Yutzey, Aaron M. Zorn, Tanya V. Kalin, John M. Shannon, Vladimir V. Kalinichenko

Dev Biol. Author manuscript; available in PMC 2019 Nov 1.

Published in final edited form as: Dev Biol. 2018 Nov 1; 443(1): 50–63. Published online 2018 Aug 25. doi: 10.1016/j.ydbio.2018.08.011

PMCID:: PMC6191344

Abstract Article PDF–3.3M

Select item 612099617.

CRISPR/Cas9 Immunoengineering of Hoxb8-Immortalized Progenitor Cells for Revealing CCR7-Mediated Dendritic Cell Signaling and Migration Mechanisms in vivo

Swantje I. Hammerschmidt, Kathrin Werth, Michael Rothe, Melanie Galla, Marc Permanyer, Gwendolyn E. Patzer, Anja Bubke, David N. Frenk, Anton Selich, Lucas Lange, Axel Schambach, Berislav Bošnjak, Reinhold Förster

Front Immunol. 2018; 9: 1949. Published online 2018 Aug 28. doi: 10.3389/fimmu.2018.01949