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Select item 104954701.

Let-7 enhances murine anti-tumor CD8 T cell responses by promoting memory and antagonizing terminal differentiation

Alexandria C. Wells, Kaito A. Hioki, Constance C. Angelou, Adam C. Lynch, Xueting Liang, Daniel J. Ryan, Iris Thesmar, Saule Zhanybekova, Saulius Zuklys, Jacob Ullom, Agnes Cheong, Jesse Mager, Georg A. Hollander, Elena L. Pobezinskaya, Leonid A. Pobezinsky

Nat Commun. 2023; 14: 5585. Published online 2023 Sep 11. doi: 10.1038/s41467-023-40959-7

PMCID:: PMC10495470

Abstract Article PDF–2.5M

Select item 95567182.

Mesenchymal stem cells exosomal let-7a-5p improve autophagic flux and alleviate liver injury in acute-on-chronic liver failure by promoting nuclear expression of TFEB

Dengna Lin, Hao Chen, Jing Xiong, Jing Zhang, Zhaoxia Hu, Juan Gao, Bin Gao, Shaoquan Zhang, Junfeng Chen, Huijuan Cao, Zhihui Li, Bingliang Lin, Zhiliang Gao

Cell Death Dis. 2022 Oct; 13(10): 865. Published online 2022 Oct 12. doi: 10.1038/s41419-022-05303-9

PMCID:: PMC9556718

Abstract Article PDF–5.2M

Select item 90292603.

Developmental maturation of the hematopoietic system controlled by a Lin28b-let-7-Cbx2 axis

Dahai Wang, Mayuri Tanaka-Yano, Eleanor Meader, Melissa A. Kinney, Vivian Morris, Edroaldo Lummertz da Rocha, Nan Liu, Tianxin Liu, Qian Zhu, Stuart H. Orkin, Trista E. North, George Q. Daley, R. Grant Rowe

Cell Rep. Author manuscript; available in PMC 2022 Apr 22.

Published in final edited form as: Cell Rep. 2022 Apr 5; 39(1): 110587. doi: 10.1016/j.celrep.2022.110587

PMCID:: PMC9029260

Abstract Article PDF–3.1M

Select item 89752954.

Protection by microRNA-7a-5p Antagomir Against Intestinal Mucosal Injury Related to the JNK Pathway in TNBS-Induced Experimental Colitis

Bao Yin, Huang Tian-Chu, Xu Ling-Fen

Turk J Gastroenterol. 2021 May; 32(5): 431–436. Published online 2021 May 1. doi: 10.5152/tjg.2021.20746

PMCID:: PMC8975295

Abstract Article PDF–1.6M

Select item 89568285.

Uterine miR-877-3p and let-7a-5p are increased during simulated menstruation in a mouse model

Marianne Watters, Catherine A Walker, Alison A Murray, Moira Nicol, Jacqueline A Maybin

Reprod Fertil. 2022 Jan 1; 3(1): L3–L5. Published online 2022 Feb 17. doi: 10.1530/RAF-21-0112

PMCID:: PMC8956828

Abstract Article PDF–457K

Select item 84245206.

Feedback repression of PPARα signaling by Let-7 microRNA

Tomoki Yagai, Tingting Yan, Yuhong Luo, Shogo Takahashi, Daisuke Aibara, Donghwan Kim, Chad N. Brocker, Moshe Levi, Hozumi Motohashi, Frank J. Gonzalez

Cell Rep. Author manuscript; available in PMC 2021 Sep 8.

Published in final edited form as: Cell Rep. 2021 Aug 10; 36(6): 109506. doi: 10.1016/j.celrep.2021.109506

PMCID:: PMC8424520

Abstract Article PDF–1.7M

Select item 80763047.

MicroRNA Let-7 targets AMPK and impairs hepatic lipid metabolism in offspring of maternal obese pregnancies

Laís A. P. Simino, Carolina Panzarin, Marina F. Fontana, Thais de Fante, Murilo V. Geraldo, Letícia M. Ignácio-Souza, Marciane Milanski, Marcio A. Torsoni, Michael G. Ross, Mina Desai, Adriana S. Torsoni

Sci Rep. 2021; 11: 8980. Published online 2021 Apr 26. doi: 10.1038/s41598-021-88518-8

PMCID:: PMC8076304

Abstract Article PDF–4.0M

Select item 79066028.

Repressing Ago2 mRNA translation by Trim71 maintains pluripotency through inhibiting let-7 microRNAs

Qiuying Liu, Xiaoli Chen, Mariah K Novak, Shaojie Zhang, Wenqian Hu

eLife. 2021; 10: e66288. Published online 2021 Feb 18. doi: 10.7554/eLife.66288

PMCID:: PMC7906602

Abstract Article PDF–3.2M

Select item 77265609.

PMO-based let-7c site blocking oligonucleotide (SBO) mediated utrophin upregulation in mdx mice, a therapeutic approach for Duchenne muscular dystrophy (DMD)

Kasturi Sengupta, Emanuele Loro, Tejvir S. Khurana

Sci Rep. 2020; 10: 21492. Published online 2020 Dec 9. doi: 10.1038/s41598-020-76338-1

PMCID:: PMC7726560

Abstract Article PDF–2.8M

Select item 703547410.

An ontogenetic switch drives the positive and negative selection of B cells

Xijin Xu, Mukta Deobagkar-Lele, Katherine R. Bull, Tanya L. Crockford, Adam J. Mead, Adam P. Cribbs, David Sims, Consuelo Anzilotti, Richard J. Cornall

Proc Natl Acad Sci U S A. 2020 Feb 18; 117(7): 3718–3727. Published online 2020 Feb 4. doi: 10.1073/pnas.1915247117

PMCID:: PMC7035474

Abstract Article PDF–1.8M

Select item 698480511.

Circular RNA_101237 mediates anoxia/reoxygenation injury by targeting let-7a-5p/IGF2BP3 in cardiomyocytes

Jianting Gan, Jun Yuan, Yu Liu, Zhengde Lu, Yan Xue, Lei Shi, Huayuan Zeng

Int J Mol Med. 2020 Feb; 45(2): 451–460. Published online 2019 Dec 23. doi: 10.3892/ijmm.2019.4441

PMCID:: PMC6984805

Abstract Article PDF–1.2M

Select item 690270512.

Heterochronic regulation of lung development via the Lin28–Let-7 pathway

Nelly Komarovsky Gulman, Leah Armon, Tali Shalit, Achia Urbach

FASEB J. 2019 Nov; 33(11): 12008–12018. Published online 2019 Aug 7. doi: 10.1096/fj.201802702R

PMCID:: PMC6902705

Abstract Article

Select item 681483913.

Let-7 regulates cell cycle dynamics in the developing cerebral cortex and retina

Corinne L. A. Fairchild, Simranjeet K. Cheema, Joanna Wong, Keiko Hino, Sergi Simó, Anna La Torre

Sci Rep. 2019; 9: 15336. Published online 2019 Oct 25. doi: 10.1038/s41598-019-51703-x

Correction in:: Sci Rep. 2021; 11: 2872.

PMCID:: PMC6814839

Abstract Article PDF–12M

Select item 676512514.

MicroRNAs miR-25, let-7 and miR-124 regulate the neurogenic potential of Müller glia in mice

Stefanie G. Wohl, Marcus J. Hooper, Thomas A. Reh

Development. 2019 Sep 1; 146(17): dev179556. Published online 2019 Sep 2. doi: 10.1242/dev.179556

PMCID:: PMC6765125

Abstract Article

Select item 633521115.

A novel, noncoding-RNA-mediated, post-transcriptional mechanism of anti-Mullerian hormone regulation by the H19/let-7 axis

Chunrong Qin, Xi Xia, Yanhong Fan, Ying Jiang, Yong Chen, Na Zhang, Bahar Uslu, Joshua Johnson, Amanda N Kallen

Biol Reprod. 2019 Jan; 100(1): 101–111. Published online 2018 Aug 21. doi: 10.1093/biolre/ioy172

Correction in:: Biol Reprod. 2019 Jul; 101(1): 257.

PMCID:: PMC6335211

Abstract Article PDF–1.4M

Select item 630066516.

Integrin CD11b activation drives anti-tumor innate immunity

Michael C. Schmid, Samia Q. Khan, Megan M. Kaneda, Paulina Pathria, Ryan Shepard, Tiani L. Louis, Sudarshan Anand, Gyunghwi Woo, Chris Leem, M. Hafeez Faridi, Terese Geraghty, Anugraha Rajagopalan, Seema Gupta, Mansoor Ahmed, Roberto I. Vazquez-Padron, David A. Cheresh, Vineet Gupta, Judith A. Varner

Nat Commun. 2018; 9: 5379. Published online 2018 Dec 19. doi: 10.1038/s41467-018-07387-4

PMCID:: PMC6300665

Abstract Article PDF–3.3M

Select item 591692617.

Repression of let-7a cluster prevents adhesion of colorectal cancer cells by enforcing a mesenchymal phenotype in presence of liver inflammation

Lipeng Cheng, Li Geng, Binghua Dai, Tao Zheng, Jun Fu, Liang Qiao, Wenchang Cai, Yue Wang, Jiamei Yang

Cell Death Dis. 2018 May; 9(5): 489. Published online 2018 Apr 25. doi: 10.1038/s41419-018-0477-1

PMCID:: PMC5916926

Abstract Article PDF–3.0M

Select item 584250818.

Parkinson’s Disease-Associated Mutant LRRK2-Mediated Inhibition of miRNA Activity is Antagonized by TRIM32

Laura Gonzalez-Cano, Ingeborg Menzl, Johan Tisserand, Sarah Nicklas, Jens C. Schwamborn

Mol Neurobiol. 2018; 55(4): 3490–3498. Published online 2017 May 15. doi: 10.1007/s12035-017-0570-y

PMCID:: PMC5842508

Abstract Article PDF–1.5M

Select item 570659119.

microRNA let‐7g suppresses PDGF‐induced conversion of vascular smooth muscle cell into the synthetic phenotype

Tzu‐Ming Wang, Ku‐Chung Chen, Po‐Yuan Hsu, Hsiu‐Fen Lin, Yung‐Song Wang, Chien‐Yuan Chen, Yi‐Chu Liao, Suh‐Hang H. Juo

J Cell Mol Med. 2017 Dec; 21(12): 3592–3601. Published online 2017 Jul 12. doi: 10.1111/jcmm.13269

PMCID:: PMC5706591

Abstract Article PDF–898K

Select item 555027920.

Modulation of let-7 miRNAs controls the differentiation of effector CD8 T cells

Alexandria C Wells, Keith A Daniels, Constance C Angelou, Eric Fagerberg, Amy S Burnside, Michele Markstein, Dominique Alfandari, Raymond M Welsh, Elena L Pobezinskaya, Leonid A Pobezinsky

eLife. 2017; 6: e26398. Published online 2017 Jul 24. doi: 10.7554/eLife.26398