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Select item 109876621.

Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin

Uttkarsh Ayyangar, Aneesh Karkhanis, Heather Tay, Aliya Farissa Binte Afandi, Oindrila Bhattacharjee, Lalitha KS, Sze Han Lee, James Chan, Srikala Raghavan

EMBO J. 2024 Apr; 43(7): 1113–1134. Published online 2024 Feb 28. doi: 10.1038/s44318-024-00039-y

PMCID:: PMC10987662

Abstract Article PDF–12M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 102787383.

IGFBP-3 promotes cachexia-associated lipid loss by suppressing insulin-like growth factor/insulin signaling

Xiaohui Wang, Jia Li, Wei Zhang, Feng Wang, Yunzi Wu, Yulin Guo, Dong Wang, Xinfeng Yu, Ang Li, Fei Li, Yibin Xie

Chin Med J (Engl) 2023 Apr 20; 136(8): 974–985. Published online 2003 Apr 4. doi: 10.1097/CM9.0000000000002628

PMCID:: PMC10278738

Abstract Article PDF–11M

Select item 97361604.

Insulin-like Growth Factor Binding Protein 3 Increases Mouse Preimplantation Embryo Cleavage Rate by Activation of IGF1R and EGFR Independent of IGF1 Signalling

Charmaine J. Green, Miriam Span, Monique H. Rayhanna, Marisa Perera, Margot L. Day

Cells. 2022 Dec; 11(23): 3762. Published online 2022 Nov 24. doi: 10.3390/cells11233762

PMCID:: PMC9736160

Abstract Article PDF–2.2M

Select item 90001575.

IGFBP-3 Regulates Mitochondrial Hyperfusion and Metabolic Activity in Ocular Surface Epithelia during Hyperosmolar Stress

Whitney L. Stuard, Melis K. Guner, Danielle M. Robertson

Int J Mol Sci. 2022 Apr; 23(7): 4066. Published online 2022 Apr 6. doi: 10.3390/ijms23074066

PMCID:: PMC9000157

Abstract Article PDF–3.9M

Select item 87516406.

The imprinted Igf2-Igf2r axis is critical for matching placental microvasculature expansion to fetal growth

Ionel Sandovici, Aikaterini Georgopoulou, Vicente Pérez-García, Antonia Hufnagel, Jorge López-Tello, Brian Y.H. Lam, Samira N. Schiefer, Chelsea Gaudreau, Fátima Santos, Katharina Hoelle, Giles S.H. Yeo, Keith Burling, Moritz Reiterer, Abigail L. Fowden, Graham J. Burton, Cristina M. Branco, Amanda N. Sferruzzi-Perri, Miguel Constância

Dev Cell. 2022 Jan 10; 57(1): 63–79.e8. doi: 10.1016/j.devcel.2021.12.005

PMCID:: PMC8751640

Abstract Article

Select item 86550337.

Single-cell analysis identifies a key role for Hhip in murine coronal suture development

Greg Holmes, Ana S. Gonzalez-Reiche, Madrikha Saturne, Susan M. Motch Perrine, Xianxiao Zhou, Ana C. Borges, Bhavana Shewale, Joan T. Richtsmeier, Bin Zhang, Harm van Bakel, Ethylin Wang Jabs

Nat Commun. 2021; 12: 7132. Published online 2021 Dec 8. doi: 10.1038/s41467-021-27402-5

PMCID:: PMC8655033

Abstract Article PDF–8.4M

Select item 85602118.

Endocardial/endothelial angiocrines regulate cardiomyocyte development and maturation and induce features of ventricular non-compaction

Siyeon Rhee, David T Paik, Johnson Y Yang, Danielle Nagelberg, Ian Williams, Lei Tian, Robert Roth, Mark Chandy, Jiyeon Ban, Nadjet Belbachir, Seokho Kim, Hao Zhang, Ragini Phansalkar, Ka Man Wong, Devin A King, Caroline Valdez, Virginia D Winn, Ashby J Morrison, Joseph C Wu, Kristy Red-Horse

Eur Heart J. 2021 Nov 1; 42(41): 4264–4276. Published online 2021 Jul 19. doi: 10.1093/eurheartj/ehab298

PMCID:: PMC8560211

Abstract Article PDF–1.8M

Select item 83157389.

RP58 Represses Transcriptional Programs Linked to Nonneuronal Cell Identity and Glioblastoma Subtypes in Developing Neurons

Chaomei Xiang, Karla K. Frietze, Yingtao Bi, Yanwen Li, Valentina Dal Pozzo, Sharmistha Pal, Noah Alexander, Valerie Baubet, Victoria D’Acunto, Christopher E. Mason, Ramana V. Davuluri, Nadia Dahmane

Mol Cell Biol. 2021 Jul; 41(7): e00526-20. Prepublished online 2021 Apr 26. Published online 2021 Jun 23. doi: 10.1128/MCB.00526-20

PMCID:: PMC8315738

Abstract Article PDF–7.7M

Select item 831323910.

Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development

Francesco Bedogni, Robert F. Hevner

Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034

PMCID:: PMC8313239

Abstract Article PDF–1.6M

Select item 820043911.

Increased myocellular lipid and IGFBP‐3 expression in a pre‐clinical model of pancreatic cancer‐related skeletal muscle wasting

Calvin L. Cole, John F. Bachman, Jian Ye, Joseph Murphy, Scott A. Gerber, Christopher A. Beck, Brendan F. Boyce, Gowrishankar Muthukrishnan, Joe V. Chakkalakal, Edward M. Schwarz, David Linehan

J Cachexia Sarcopenia Muscle. 2021 Jun; 12(3): 731–745. Published online 2021 May 7. doi: 10.1002/jcsm.12699

PMCID:: PMC8200439

Abstract Article PDF–19M

Select item 818971912.

Novel cell types and developmental lineages revealed by single-cell RNA-seq analysis of the mouse crista ampullaris

Brent A Wilkerson, Heather L Zebroski, Connor R Finkbeiner, Alex D Chitsazan, Kylie E Beach, Nilasha Sen, Renee C Zhang, Olivia Bermingham-McDonogh

eLife. 2021; 10: e60108. Published online 2021 May 18. doi: 10.7554/eLife.60108

PMCID:: PMC8189719

Abstract Article PDF–15M

Select item 766312313.

Targeted Disruption of Mouse Dip2B Leads to Abnormal Lung Development and Prenatal Lethality

Rajiv Kumar Sah, Jun Ma, Fatoumata Binta Bah, Zhenkai Xing, Salah Adlat, Zin Ma Oo, Yajun Wang, Noor Bahadar, Ameer Ali Bohio, Farooq Hayel Nagi, Xuechao Feng, Luqing Zhang, Yaowu Zheng

Int J Mol Sci. 2020 Nov; 21(21): 8223. Published online 2020 Nov 3. doi: 10.3390/ijms21218223

PMCID:: PMC7663123

Abstract Article PDF–4.7M

Select item 765649014.

Insulin-like Growth Factor-I is Inversely Related to Adiposity in Overweight Latino Children

Claudia M. Toledo-Corral, Christian K. Roberts, Gabriel Q. Shaibi, Christianne J. Lane, Paul B. Higgins, Jaimie N. Davis, Marc J. Weigensberg, Michael I. Goran

J Pediatr Endocrinol Metab. Author manuscript; available in PMC 2020 Nov 11.

Published in final edited form as: J Pediatr Endocrinol Metab. 2008 Sep; 21(9): 855–864. doi: 10.1515/jpem.2008.21.9.855

PMCID:: PMC7656490

Abstract Article PDF–532K

Select item 737917615.

Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis

Greg Holmes, Ana S. Gonzalez-Reiche, Na Lu, Xianxiao Zhou, Joshua Rivera, Divya Kriti, Robert Sebra, Anthony A. Williams, Michael J. Donovan, S. Steven Potter, Dalila Pinto, Bin Zhang, Harm van Bakel, Ethylin Wang Jabs

Cell Rep. Author manuscript; available in PMC 2020 Jul 24.

Published in final edited form as: Cell Rep. 2020 Jul 7; 32(1): 107871. doi: 10.1016/j.celrep.2020.107871

PMCID:: PMC7379176

Abstract Article PDF–3.0M

Select item 732994516.

Role of Insulin-Like Growth Factor Binding Protein-3 in the Pathogenesis of Herpes Stromal Keratitis

Pushpa Rao, Pratima K. Suvas, Andrew D. Jerome, Jena J. Steinle, Susmit Suvas

Invest Ophthalmol Vis Sci. 2020 Feb; 61(2): 46. Published online 2020 Feb 27. doi: 10.1167/iovs.61.2.46

PMCID:: PMC7329945

Abstract Article PDF–4.8M

Select item 722702817.

Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss

Gayle B. Collin, Navdeep Gogna, Bo Chang, Nattaya Damkham, Jai Pinkney, Lillian F. Hyde, Lisa Stone, Jürgen K. Naggert, Patsy M. Nishina, Mark P. Krebs

Cells. 2020 Apr; 9(4): 931. Published online 2020 Apr 10. doi: 10.3390/cells9040931

PMCID:: PMC7227028

Abstract Article PDF–5.4M

Select item 687563918.

Glycyrrhizin protects IGFBP-3 knockout mice from retinal damage

Li Liu, Youde Jiang, Jena J. Steinle

Cytokine. Author manuscript; available in PMC 2021 Jan 1.

Published in final edited form as: Cytokine. 2020 Jan; 125: 154856. Published online 2019 Sep 14. doi: 10.1016/j.cyto.2019.154856

PMCID:: PMC6875639

Abstract Article PDF–683K

Select item 627919419.

Epac1 deacetylates HMGB1 through increased IGFBP-3 and SIRT1 levels in the retinal vasculature

Youde Jiang, Li Liu, Jena J. Steinle

Mol Vis. 2018; 24: 727–732. Published online 2018 Nov 16.

PMCID:: PMC6279194

Abstract Article PDF–1.4M

Select item 612661520.

Nuclear FAK and Runx1 cooperate to regulate IGFBP3, cell cycle progression and tumor growth

Marta Canel, Adam Byron, Andrew H. Sims, Jessy Cartier, Hitesh Patel, Margaret C. Frame, Valerie G. Brunton, Bryan Serrels, Alan Serrels

Cancer Res. Author manuscript; available in PMC 2018 Sep 6.

Published in final edited form as: Cancer Res. 2017 Oct 1; 77(19): 5301–5312. Published online 2017 Aug 14. doi: 10.1158/0008-5472.CAN-17-0418

PMCID:: PMC6126615

Abstract Article PDF–2.0M

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