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Select item 95787071.

Identification of orphan ligand-receptor relationships using a cell-based CRISPRa enrichment screening platform

Dirk H Siepe, Lukas T Henneberg, Steven C Wilson, Gaelen T Hess, Michael C Bassik, Kai Zinn, K Christopher Garcia

eLife. 2022; 11: e81398. Published online 2022 Sep 30. doi: 10.7554/eLife.81398

PMCID:: PMC9578707

Abstract Article PDF–3.3M

Select item 89414772.

CD158k and PD-1 expressions define heterogeneous subtypes of Sezary syndrome

Inès Vergnolle, Claudia Douat-Beyries, Serge Boulinguez, Jean-Baptiste Rieu, Jean-Philippe Vial, Rolande Baracou, Sylvie Boudot, Aurore Cazeneuve, Sophie Chaugne, Martine Durand, Sylvie Estival, Nicolas Lablanche, Marie-Laure Nicolau-Travers, Emilie Tournier, Laurence Lamant, François Vergez

Blood Adv. 2022 Mar 22; 6(6): 1813–1825. Published online 2022 Mar 16. doi: 10.1182/bloodadvances.2021005147

PMCID:: PMC8941477

Abstract Article PDF–1.9M

Select item 83529643.

Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer

Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger

Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y

PMCID:: PMC8352964

Abstract Article PDF–4.5M

Select item 81650304.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 73663945.

Distribution of killer cell immunoglobulin-like receptor genes in the mestizo population from Venezuela

A. Conesa, M. Fernández-Mestre, D. Padrón, F. Toro, N. Silva, P. Tassinari, I. Blanca, M.P. Martin, M. Carrington, Z. Layrisse

Tissue Antigens. Author manuscript; available in PMC 2020 Jul 17.

Published in final edited form as: Tissue Antigens. 2010 Jun; 75(6): 724–729. Published online 2010 Feb 24. doi: 10.1111/j.1399-0039.2010.01446.x

PMCID:: PMC7366394

Abstract Article PDF–441K

Select item 55316116.

Architecture of the human interactome defines protein communities and disease networks

Edward L. Huttlin, Raphael J. Bruckner, Joao A. Paulo, Joe R. Cannon, Lily Ting, Kurt Baltier, Greg Colby, Fana Gebreab, Melanie P. Gygi, Hannah Parzen, John Szpyt, Stanley Tam, Gabriela Zarraga, Laura Pontano-Vaites, Sharan Swarup, Anne E. White, Devin K. Schweppe, Ramin Rad, Brian K. Erickson, Robert A. Obar, K.G. Guruharsha, Kejie Li, Spyros Artavanis-Tsakonas, Steven P. Gygi, J. Wade Harper

Nature. Author manuscript; available in PMC 2017 Nov 17.

Published in final edited form as: Nature. 2017 May 25; 545(7655): 505–509. Published online 2017 May 17. doi: 10.1038/nature22366

PMCID:: PMC5531611

Abstract Article PDF–2.7M

Select item 49924217.

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1

Wilfredo F. Garcia-Beltran, Angelique Hölzemer, Gloria Martrus, Amy W. Chung, Yovana Pacheco, Camille R. Simoneau, Marijana Rucevic, Pedro A. Lamothe-Molina, Thomas Pertel, Tae-Eun Kim, Haley Dugan, Galit Alter, Julie Dechanet-Merville, Stephanie Jost, Mary Carrington, Marcus Altfeld

Nat Immunol. Author manuscript; available in PMC 2017 Jan 25.

Published in final edited form as: Nat Immunol. 2016 Sep; 17(9): 1067–1074. Published online 2016 Jul 25. doi: 10.1038/ni.3513

PMCID:: PMC4992421

Abstract Article PDF–1.1M

Select item 48556418.

Activation‐Induced Killer Cell Immunoglobulin‐like Receptor 3DL2 Binding to HLA–B27 Licenses Pathogenic T Cell Differentiation in Spondyloarthritis

Anna Ridley, Hiroko Hatano, Isabel Wong‐Baeza, Jacqueline Shaw, Katherine K. Matthews, Hussein Al‐Mossawi, Kristin Ladell, David A. Price, Paul Bowness, Simon Kollnberger

Arthritis Rheumatol. 2016 Mar 28; 68(4): 901–914. Published online 2016 Mar 28. doi: 10.1002/art.39515

PMCID:: PMC4855641

Abstract Article PDF–1.0M

Select item 48231739.

MHC class I protects motor neurons from astrocyte-induced toxicity in amyotrophic lateral sclerosis (ALS)

SungWon Song, Carlos J. Miranda, Lyndsey Braun, Kathrin Meyer, Ashley E. Frakes, Laura Ferraiuolo, Shibi Likhite, Adam K. Bevan, Kevin D. Foust, Michael J. McConnell, Christopher M. Walker, Brian K. Kaspar

Nat Med. Author manuscript; available in PMC 2016 Aug 29.

Published in final edited form as: Nat Med. 2016 Apr; 22(4): 397–403. Published online 2016 Feb 29. doi: 10.1038/nm.4052

PMCID:: PMC4823173

Abstract Article PDF–1.8M

Select item 462133410.

The D0 immunoglobulin-like domain plays a central role for the stronger binding of KIR3DL2 to B27 free heavy chain dimers

Hiroko Hatano, Jacqueline Shaw, Kaitlin Marquardt, Zhiyong Zhang, Laurent Gauthier, Stephanie Chanteux, Benjamin Rossi, Demin Li, Julie Mitchell, Simon Kollnberger

J Immunol. Author manuscript; available in PMC 2015 Oct 27.

Published in final edited form as: J Immunol. 2015 Feb 15; 194(4): 1591–1601. Published online 2015 Jan 12. doi: 10.4049/jimmunol.1402214

PMCID:: PMC4621334

Abstract Article PDF–1.9M

Select item 453061311.

Pemphigus is associated with KIR3DL2 expression levels and provides evidence that KIR3DL2 may bind HLA-A3 and A11 in vivo

Danillo G. Augusto, Geraldine M. O’Connor, Sara C. Lobo-Alves, Sara Bass, Maureen P. Martin, Mary Carrington, Daniel W. McVicar, Maria Luiza Petzl-Erler

Eur J Immunol. Author manuscript; available in PMC 2016 Jul 1.

Published in final edited form as: Eur J Immunol. 2015 Jul; 45(7): 2052–2060. Published online 2015 May 6. doi: 10.1002/eji.201445324

PMCID:: PMC4530613

Abstract Article PDF–973K

Select item 378071512.

HLA-F and MHC Class I Open Conformers Are Ligands for NK Cell Ig-like Receptors

Jodie P. Goodridge, Aura Burian, Ni Lee, Daniel E. Geraghty

J Immunol. 2013 Oct 1; 191(7): 3553–3562. Published online 2013 Sep 9. doi: 10.4049/jimmunol.1300081

PMCID:: PMC3780715

Abstract Article PDF–945K

Select item 373609413.

KIR3DL2 binds to HLA-B27 dimers and free heavy chains more strongly than other HLA class I and promotes the expansion of T cells in ankylosing spondylitis

Isabel Wong-Baeza, Anna Ridley, Jackie Shaw, Hiroko Hatano, Oliwia Rysnik, Kirsty McHugh, Christopher Piper, Simon Brackenbridge, Ricardo Fernandes, Anthoni Chan, Paul Bowness, Simon Kollnberger

J Immunol. Author manuscript; available in PMC 2013 Oct 1.

Published in final edited form as: J Immunol. 2013 Apr 1; 190(7): 3216–3224. Published online 2013 Feb 25. doi: 10.4049/jimmunol.1202926

PMCID:: PMC3736094

Abstract Article PDF–3.5M

Select item 347684614.

The Characteristics of Allelic Polymorphism in Killer Immunoglobulin-Like Receptor Framework Genes in African Americans

LiHua Hou, Bo Jiang, Minghua Chen, Jennifer Ng, Carolyn Katovich Hurley

Immunogenetics. Author manuscript; available in PMC 2012 Oct 19.

Published in final edited form as: Immunogenetics. 2011 Sep; 63(9): 549–559. Published online 2011 May 24. doi: 10.1007/s00251-011-0536-6

PMCID:: PMC3476846

Abstract Article PDF–123K

Select item 331091115.

Global landscape of HIV–human protein complexes

Stefanie Jäger, Peter Cimermancic, Natali Gulbahce, Jeffrey R. Johnson, Kathryn E. McGovern, Starlynn C. Clarke, Michael Shales, Gaelle Mercenne, Lars Pache, Kathy Li, Hilda Hernandez, Gwendolyn M. Jang, Shoshannah L. Roth, Eyal Akiva, John Marlett, Melanie Stephens, Ivan D’Orso, Jason Fernandes, Marie Fahey, Cathal Mahon, Anthony J. O’Donoghue, Aleksandar Todorovic, John H. Morris, David A. Maltby, Tom Alber, Gerard Cagney, Frederic D. Bushman, John A. Young, Sumit K. Chanda, Wesley I. Sundquist, Tanja Kortemme, Ryan D. Hernandez, Charles S. Craik, Alma Burlingame, Andrej Sali, Alan D. Frankel, Nevan J. Krogan

Nature. Author manuscript; available in PMC 2013 Jan 19.

Published in final edited form as: Nature. 2011 Dec 21; 481(7381): 365–370. Published online 2011 Dec 21. doi: 10.1038/nature10719

PMCID:: PMC3310911

Abstract Article PDF–1.8M

Select item 321056116.

Th17 cells expressing KIR3DL2+ and responsive to HLA-B27 homodimers are increased in Ankylosing Spondylitis

Paul Bowness, Anna Ridley, Jacqueline Shaw, Antoni T Chan, Isabel Wong Baeza, Myles Fleming, Fraser Cummings, Andrew McMichael, Simon Kollnberger

J Immunol. Author manuscript; available in PMC 2011 Nov 8.

Published in final edited form as: J Immunol. 2011 Feb 15; 186(4): 2672–2680. Published online 2011 Jan 19. doi: 10.4049/jimmunol.1002653

PMCID:: PMC3210561

Abstract Article PDF–1.5M

Select item 317805917.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 297832018.

Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection

Nadia Wauquier, Cindy Padilla, Pierre Becquart, Eric Leroy, Vincent Vieillard

Immunogenetics. 2010; 62(11): 767–771. Published online 2010 Sep 29. doi: 10.1007/s00251-010-0480-x

PMCID:: PMC2978320

Abstract Article PDF–174K

Select item 291655119.

Influence of HLA Class I and HLA-KIR Compound Genotypes on HIV-2 Infection and Markers of Disease Progression in a Manjako Community in West Africa

Louis-Marie Yindom, Aleksandra Leligdowicz, Maureen P. Martin, Xiaojiang Gao, Ying Qi, Syed M. A. Zaman, Maarten Schim van der Loeff, Carla van Tienen, Assan Jaye, Akum Aveika, Archibald Worwui, Mathurin Diatta, Tim Vincent, Hilton C. Whittle, Sarah L. Rowland-Jones, Robert Walton, Mary Carrington

J Virol. 2010 Aug; 84(16): 8202–8208. Published online 2010 Jun 2. doi: 10.1128/JVI.00116-10

PMCID:: PMC2916551

Abstract Article PDF–517K

Select item 281503920.

Activating KIR receptors 3DS1 and 2DS1 protect against developing the severe form of recurrent respiratory papillomatosis

Vincent R. Bonagura, Zeying Du, Elham Ashouri, Lihui Luo, Lynda J. Hatam, James A. DeVoti, David W. Rosenthal, Bettie M. Steinberg, Allan L. Abramson, David W. Gjertson, Elaine F. Reed, Raja Rajalingam

Hum Immunol. Author manuscript; available in PMC 2011 Feb 1.

Published in final edited form as: Hum Immunol. 2010 Feb; 71(2): 212. Published online 2009 Oct 25. doi: 10.1016/j.humimm.2009.10.009

PMCID:: PMC2815039

Abstract Article PDF–1.4M

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