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Select item 103557031.

Exploratory Analysis of Plasma Neurotensin as a Novel Biomarker for Early Detection of Colorectal Polyp and Cancer

Shengyang Qiu, Stella Nikolaou, Francesca Fiorentino, Shahnawaz Rasheed, Ara Darzi, David Cunningham, Paris Tekkis, Christos Kontovounisios

Horm Cancer. 2019 Jun; 10(2-3): 128–135. Published online 2019 May 15. doi: 10.1007/s12672-019-00364-3

PMCID:: PMC10355703

Abstract Article PDF–455K

Select item 100951032.

Neurotensin Gene rs2234762 C>G Variant Associates with Reduced Circulating Pro-NT Levels and Predicts Lower Insulin Resistance in Overweight/Obese Children

Federica Sentinelli, Ilaria Barchetta, Flavia Agata Cimini, Sara Dule, Diego Bailetti, Efisio Cossu, Arcangelo Barbonetti, Maria Totaro, Olle Melander, Maria Gisella Cavallo, Marco Giorgio Baroni

Int J Mol Sci. 2023 Apr; 24(7): 6460. Published online 2023 Mar 30. doi: 10.3390/ijms24076460

PMCID:: PMC10095103

Abstract Article PDF–505K

Select item 100025933.

Neurotensin and Its Involvement in Reproductive Functions: An Exhaustive Review of the Literature

Pauline Arbogast, Guillaume Gauchotte, Romane Mougel, Olivier Morel, Ahmed Ziyyat, Mikaël Agopiantz

Int J Mol Sci. 2023 Mar; 24(5): 4594. Published online 2023 Feb 27. doi: 10.3390/ijms24054594

PMCID:: PMC10002593

Abstract Article PDF–1.1M

Select item 99305684.

Ligands selectively tune the local and global motions of neurotensin receptor 1 (NTS₁)

Fabian Bumbak, Miquel Pons, Asuka Inoue, Juan Carlos Paniagua, Fei Yan, Hongwei Wu, Scott A. Robson, Ross A.D. Bathgate, Daniel J. Scott, Paul R. Gooley, Joshua J. Ziarek

Cell Rep. Author manuscript; available in PMC 2023 Feb 15.

Published in final edited form as: Cell Rep. 2023 Jan 31; 42(1): 112015. Published online 2023 Jan 20. doi: 10.1016/j.celrep.2023.112015

PMCID:: PMC9930568

Abstract Article PDF–2.5M

Select item 84850775.

Neurotensin: a neuropeptide induced by hCG in the human and rat ovary during the periovulatory period

Linah Al-Alem, Muraly Puttabyatappa, Ketan Shrestha, Yohan Choi, Kathy Rosewell, Mats Brännström, James Akin, Misung Jo, Diane M Duffy, Thomas E Curry, Jr

Biol Reprod. 2021 Jun; 104(6): 1337–1346. Published online 2021 Mar 4. doi: 10.1093/biolre/ioab036

PMCID:: PMC8485077

Abstract Article PDF–1.0M

Select item 83726466.

Pro-Neurotensin/Neuromedin N and Risk of Incident Metabolic Syndrome and Diabetes Mellitus in the REGARDS Cohort

Charles D Nicoli, April P Carson, Timothy B Plante, D Leann Long, Leslie A McClure, Janin Schulte, Mary Cushman

J Clin Endocrinol Metab. 2021 Sep; 106(9): e3483–e3494. Published online 2021 May 20. doi: 10.1210/clinem/dgab355

PMCID:: PMC8372646

Abstract Article

Select item 79587147.

A Major Lineage of Enteroendocrine Cells Coexpress CCK, Secretin, GIP, GLP-1, PYY, and Neurotensin but Not Somatostatin

Kristoffer L. Egerod, Maja S. Engelstoft, Kaare V. Grunddal, Mark K. Nøhr, Anna Secher, Ichiro Sakata, Jens Pedersen, Johanne A. Windeløv, Ernst-Martin Füchtbauer, Jørgen Olsen, Frank Sundler, Jan P. Christensen, Nils Wierup, Jesper V. Olsen, Jens J. Holst, Jeffrey M. Zigman, Steen S. Poulsen, Thue W. Schwartz

Endocrinology. 2012 Dec 1; 153(12): 5782–5795. Published online 2012 Dec 1. doi: 10.1210/en.2012-1595

PMCID:: PMC7958714

Abstract Article

Select item 79510508.

The Role of Central Neurotensin in Regulating Feeding and Body Weight

Jariel Ramirez-Virella, Gina M Leinninger

Endocrinology. 2021 May; 162(5): bqab038. Published online 2021 Feb 18. doi: 10.1210/endocr/bqab038

PMCID:: PMC7951050

Abstract Article

Select item 79491589.

Suppression of the NTS-CPS1 regulatory axis by AFF1 in lung adenocarcinoma cells

Junjie Yue, Qian Dai, Shaohua Hao, Shiqi Zhu, Xiaoxu Liu, Zhiqun Tang, Meng Li, Haitong Fang, Chengqi Lin, Zhuojuan Luo

J Biol Chem. 2021 Jan-Jun; 296: 100319. Published online 2021 Jan 22. doi: 10.1016/j.jbc.2021.100319

PMCID:: PMC7949158

Abstract Article PDF–1.9M

Select item 774592310.

Ligand-mediated dephosphorylation signaling for MAP kinase

Nataliia V. Shults, Faisal S. Almansour, Vladyslava Rybka, Dante I. Suzuki, Yuichiro J. Suzuki

Cell Signal. Author manuscript; available in PMC 2020 Dec 17.

Published in final edited form as: Cell Signal. 2018 Dec; 52: 147–154. Published online 2018 Sep 10. doi: 10.1016/j.cellsig.2018.09.005

PMCID:: PMC7745923

Abstract Article PDF–1.8M

Select item 770804511.

Generation of onco-enhancer enhances chromosomal remodeling and accelerates tumorigenesis

Peiwei Chai, Jie Yu, Ruobing Jia, Xuyang Wen, Tianyi Ding, Xiaoyu Zhang, Hongyan Ni, Renbing Jia, Shengfang Ge, He Zhang, Xianqun Fan

Nucleic Acids Res. 2020 Dec 2; 48(21): 12135–12150. Published online 2020 Nov 16. doi: 10.1093/nar/gkaa1051

PMCID:: PMC7708045

Abstract Article PDF–4.6M

Select item 746440412.

Characterisation of the Expression of Neurotensin and Its Receptors in Human Colorectal Cancer and Its Clinical Implications

Shengyang Qiu, Stella Nikolaou, Jie Zhu, Peter Jeffery, Robert Goldin, James Kinross, James L. Alexander, Shahnawaz Rasheed, Paris Tekkis, Christos Kontovounisios

Biomolecules. 2020 Aug; 10(8): 1145. Published online 2020 Aug 5. doi: 10.3390/biom10081145

PMCID:: PMC7464404

Abstract Article PDF–6.0M

Select item 718361613.

The role of Neurotensin and its receptors in non-gastrointestinal cancers: a review

Stella Nikolaou, Shengyang Qiu, Francesca Fiorentino, Constantinos Simillis, Shahnawaz Rasheed, Paris Tekkis, Christos Kontovounisios

Cell Commun Signal. 2020; 18: 68. Published online 2020 Apr 26. doi: 10.1186/s12964-020-00569-y

PMCID:: PMC7183616

Abstract Article PDF–1.1M

Select item 716998314.

A reference map of the human binary protein interactome

Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood

Nature. Author manuscript; available in PMC 2020 Oct 8.

Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x

PMCID:: PMC7169983

Abstract Article PDF–5.4M

Select item 708421115.

Upregulation of Thr/Tyr kinase Increases the Cancer Progression by Neurotensin and Dihydropyrimidinase-Like 3 in Lung Cancer

Ying-Ming Tsai, Kuan-Li Wu, Yung-Yun Chang, Jen-Yu Hung, Wei-An Chang, Chao-Yuan Chang, Shu-Fang Jian, Pei-Hsun Tsai, Yung-Chi Huang, Inn-Wen Chong, Ya-Ling Hsu

Int J Mol Sci. 2020 Mar; 21(5): 1640. Published online 2020 Feb 28. doi: 10.3390/ijms21051640

PMCID:: PMC7084211

Abstract Article PDF–10M

Select item 675622116.

Neurotensin and its receptors mediate neuroendocrine transdifferentiation in prostate cancer

Shimiao Zhu, Hao Tian, Xiaodan Niu, Jiang Wang, Xing Li, Ning Jiang, Simeng Wen, Xuanrong Chen, Shancheng Ren, Chuanliang Xu, Chawnshang Chang, Amilcar Flores-Morales, Zhiqun Shang, Yinghao Sun, Yuanjie Niu

Oncogene. 2019; 38(24): 4875–4884. Published online 2019 Feb 15. doi: 10.1038/s41388-019-0750-5

Correction in:: Oncogene. 2019; 38(24): 4885.

PMCID:: PMC6756221

Abstract Article PDF–2.7M

Select item 668667117.

High Plasma Neurotensin Levels in Children with Prader–Willi Syndrome

Merlin G. Butler, Tommy A. Nelson, Daniel J. Driscoll, Ann M. Manzardo

Am J Med Genet A. Author manuscript; available in PMC 2019 Aug 8.

Published in final edited form as: Am J Med Genet A. 2015 Aug; 167A(8): 1773–1778. Published online 2015 Apr 5. doi: 10.1002/ajmg.a.37103

PMCID:: PMC6686671

Abstract Article PDF–201K

Select item 651499218.

Intermittent Hypoxia Up-Regulates Gene Expressions of Peptide YY (PYY), Glucagon-like Peptide-1 (GLP-1), and Neurotensin (NTS) in Enteroendocrine Cells

Ryogo Shobatake, Asako Itaya-Hironaka, Akiyo Yamauchi, Mai Makino, Sumiyo Sakuramoto-Tsuchida, Tomoko Uchiyama, Hiroyo Ota, Nobuyuki Takahashi, Satoshi Ueno, Kazuma Sugie, Shin Takasawa

Int J Mol Sci. 2019 Apr; 20(8): 1849. Published online 2019 Apr 15. doi: 10.3390/ijms20081849

PMCID:: PMC6514992

Abstract Article PDF–1.6M

Select item 559135219.

The role of neurotensin as a novel biomarker in the endoscopic screening of high-risk population for developing colorectal neoplasia

Christos Kontovounisios, Shengyang Qiu, Shahnawaz Rasheed, Ara Darzi, Paris Tekkis

Updates Surg. 2017; 69(3): 397–402. Published online 2017 May 30. doi: 10.1007/s13304-017-0464-6

PMCID:: PMC5591352

Abstract Article PDF–546K

Select item 552785620.

Neurotensin signaling induces intracellular alkalinization and interleukin‐8 expression in human pancreatic cancer cells

Ulrike Olszewski, Gerhard Hamilton

Mol Oncol. 2009 Jun; 3(3): 204–213. Published online 2009 Feb 3. doi: 10.1016/j.molonc.2009.01.006

PMCID:: PMC5527856

Abstract Article PDF–383K

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