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Select item 109902771.

ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication

Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton

Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012

PMCID:: PMC10990277

Abstract Article PDF–3.9M

Select item 103808002.

The Role of TRPM4 in Cardiac Electrophysiology and Arrhythmogenesis

Yaopeng Hu, Jiehui Cang, Keizo Hiraishi, Takayuki Fujita, Ryuji Inoue

Int J Mol Sci. 2023 Jul; 24(14): 11798. Published online 2023 Jul 22. doi: 10.3390/ijms241411798

PMCID:: PMC10380800

Abstract Article PDF–657K

Select item 100860373.

Influence of TRPM4 rs8104571 genotype on intracranial pressure and outcomes in African Americans with traumatic brain injury

Joseph D. Krocker, Madeline E. Cotton, Jacob B. Schriner, Baron K. Osborn, Michael M. Talanker, Yao-Wei W. Wang, Charles S. Cox, Jr., Charles E. Wade

Sci Rep. 2023; 13: 5815. Published online 2023 Apr 10. doi: 10.1038/s41598-023-32819-7

PMCID:: PMC10086037

Abstract Article PDF–1.0M

Select item 94406534.

Suppression of ACE2 SUMOylation protects against SARS-CoV-2 infection through TOLLIP-mediated selective autophagy

Shouheng Jin, Xing He, Ling Ma, Zhen Zhuang, Yiliang Wang, Meng Lin, Sihui Cai, Lu Wei, Zheyu Wang, Zhiyao Zhao, Yaoxing Wu, Lin Sun, Chunwei Li, Weihong Xie, Yong Zhao, Zhou Songyang, Ke Peng, Jincun Zhao, Jun Cui

Nat Commun. 2022; 13: 5204. Published online 2022 Sep 3. doi: 10.1038/s41467-022-32957-y

PMCID:: PMC9440653

Abstract Article PDF–2.9M

Select item 92626145.

A dual-activity topoisomerase complex regulates mRNA translation and turnover

Shuaikun Su, Yutong Xue, Alexei Sharov, Yongqing Zhang, Seung Kyu Lee, Jennifer L Martindale, Wen Li, Wai Lim Ku, Keji Zhao, Supriyo De, Weiping Shen, Payel Sen, Myriam Gorospe, Dongyi Xu, Weidong Wang

Nucleic Acids Res. 2022 Jul 8; 50(12): 7013–7033. Published online 2022 Jun 24. doi: 10.1093/nar/gkac538

PMCID:: PMC9262614

Abstract Article PDF–3.6M

Select item 91804136.

A Novel Role of the TRPM4 Ion Channel in Exocytosis

Paulina Stokłosa, Sven Kappel, Christine Peinelt

Cells. 2022 Jun; 11(11): 1793. Published online 2022 May 30. doi: 10.3390/cells11111793

PMCID:: PMC9180413

Abstract Article PDF–2.9M

Select item 91706237.

Variants in genes encoding the SUR1-TRPM4 non-selective cation channel and sudden infant death syndrome (SIDS): potentially increased risk for cerebral edema

Dong Qu, Peter Schürmann, Thomas Rothämel, Thilo Dörk, Michael Klintschar

Int J Legal Med. 2022; 136(4): 1113–1120. Published online 2022 Apr 26. doi: 10.1007/s00414-022-02819-9

PMCID:: PMC9170623

Abstract Article PDF–853K

Select item 91703328.

The novel TRPM4 c.448G>T variant is associated with familial conduction disorders, cardiomyopathy, and sudden cardiac death

Boldizsar Kovacs, Stephan Winnik, Argelia Medeiros-Domingo, Sarah Costa, Guan Fu, Saskia Biskup, Frank Ruschitzka, Andreas J. Flammer, Felix C. Tanner, Firat Duru, Ardan M. Saguner

Cardiol J. 2022; 29(3): 514–516. Published online 2022 May 31. doi: 10.5603/CJ.a2021.0157

PMCID:: PMC9170332

Article PDF–283K

Select item 89515569.

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins

Danielle G. May, Laura Martin-Sancho, Valesca Anschau, Sophie Liu, Rachel J. Chrisopulos, Kelsey L. Scott, Charles T. Halfmann, Ramon Díaz Peña, Dexter Pratt, Alexandre R. Campos, Kyle J. Roux

Viruses. 2022 Mar; 14(3): 611. Published online 2022 Mar 15. doi: 10.3390/v14030611

PMCID:: PMC8951556

Abstract Article PDF–4.4M

Select item 839517310.

Theoretical Investigation of the Mechanism by which A Gain-of-Function Mutation of the TRPM4 Channel Causes Conduction Block

Yaopeng Hu, Qin Li, Yanghua Shen, Takayuki Fujita, Xin Zhu, Ryuji Inoue

Int J Mol Sci. 2021 Aug; 22(16): 8513. Published online 2021 Aug 7. doi: 10.3390/ijms22168513

PMCID:: PMC8395173

Abstract Article PDF–3.0M

Select item 831414111.

Genetic Variants Associated With Intraparenchymal Hemorrhage Progression After Traumatic Brain Injury

Ruchira M. Jha, Benjamin E. Zusman, Ava M. Puccio, David O. Okonkwo, Matthew Pease, Shashvat M. Desai, Matthew Leach, Yvette P. Conley, Patrick M. Kochanek

JAMA Netw Open. 2021 Jul; 4(7): e2116839. Published online 2021 Jul 26. doi: 10.1001/jamanetworkopen.2021.16839

PMCID:: PMC8314141

Abstract Article

Select item 816503012.

Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome

Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi

Cell. Author manuscript; available in PMC 2022 May 27.

Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011

PMCID:: PMC8165030

Abstract Article PDF–2.2M

Select item 807565713.

Whole-Exome Sequencing Identifies a Novel TRPM4 Mutation in a Chinese Family with Atrioventricular Block

Yi Dong, Ran Du, Liang-liang Fan, Jie-yuan Jin, Hao Huang, Ya-qin Chen, Dan-dong Bi, Rong Xiang

Biomed Res Int. 2021; 2021: 9247541. Published online 2021 Apr 17. doi: 10.1155/2021/9247541

PMCID:: PMC8075657

Abstract Article PDF–602K

Select item 794896414.

The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1

Lee D. Harris, Janic Le Pen, Nico Scholz, Juliusz Mieszczanek, Natalie Vaughan, Simon Davis, Georgina Berridge, Benedikt M. Kessler, Mariann Bienz, Julien D.F. Licchesi

J Biol Chem. 2021 Jan-Jun; 296: 100246. Published online 2021 Jan 8. doi: 10.1074/jbc.RA120.015162

PMCID:: PMC7948964

Abstract Article PDF–2.7M

Select item 791480915.

TRPM4 in Cancer—A New Potential Drug Target

Anna Borgström, Christine Peinelt, Paulina Stokłosa

Biomolecules. 2021 Feb; 11(2): 229. Published online 2021 Feb 5. doi: 10.3390/biom11020229

PMCID:: PMC7914809

Abstract Article PDF–808K

Select item 726629516.

TRPM4 is overexpressed in breast cancer associated with estrogen response and epithelial-mesenchymal transition gene sets

Kah Keng Wong, Faezahtul Arbaeyah Hussain

PLoS One. 2020; 15(6): e0233884. Published online 2020 Jun 2. doi: 10.1371/journal.pone.0233884

PMCID:: PMC7266295

Abstract Article PDF–5.6M

Select item 682224617.

TRPM4 is highly expressed in human colorectal tumor buds and contributes to proliferation, cell cycle, and invasion of colorectal cancer cells

Sven Kappel, Paulina Stokłosa, Barbara Hauert, Daniela Ross‐Kaschitza, Anna Borgström, Roland Baur, José A. Galván, Inti Zlobec, Christine Peinelt

Mol Oncol. 2019 Nov; 13(11): 2393–2405. Published online 2019 Sep 12. doi: 10.1002/1878-0261.12566

PMCID:: PMC6822246

Abstract Article PDF–3.4M

Select item 674682218.

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei

Giovanni Nassa, Giorgio Giurato, Annamaria Salvati, Valerio Gigantino, Giovanni Pecoraro, Jessica Lamberti, Francesca Rizzo, Tuula A. Nyman, Roberta Tarallo, Alessandro Weisz

Sci Data. 2019; 6: 173. Published online 2019 Sep 16. doi: 10.1038/s41597-019-0179-2

PMCID:: PMC6746822

Abstract Article PDF–2.0M

Select item 655197319.

Downstream TRPM4 Polymorphisms Are Associated with Intracranial Hypertension and Statistically Interact with ABCC8 Polymorphisms in a Prospective Cohort of Severe Traumatic Brain Injury

Ruchira M. Jha, Shashvat M. Desai, Benjamin E. Zusman, Theresa A. Koleck, Ava M. Puccio, David O. Okonkwo, Seo-Young Park, Lori A. Shutter, Patrick M. Kochanek, Yvette P. Conley

J Neurotrauma. 2019 Jun 1; 36(11): 1804–1817. Published online 2019 May 22. doi: 10.1089/neu.2018.6124

PMCID:: PMC6551973

Abstract Article PDF–18M

Select item 655126620.

FAM105A/OTULINL is a pseudodebuiquitinase of the OTU-class that localizes to the ER membrane

Derek F. Ceccarelli, Sofiia Ivantsiv, Amber Anne Mullin, Etienne Coyaud, Noah Manczyk, Pierre Maisonneuve, Igor Kurinov, Liang Zhao, Chris Go, Anne-Claude Gingras, Brian Raught, Sabine Cordes, Frank Sicheri

Structure. Author manuscript; available in PMC 2020 Jun 4.

Published in final edited form as: Structure. 2019 Jun 4; 27(6): 1000–1012.e6. Published online 2019 May 2. doi: 10.1016/j.str.2019.03.022

PMCID:: PMC6551266

Abstract Article PDF–3.4M

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