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Select item 105473001.

Crk and Crkl Are Required in the Endocardial Lineage for Heart Valve Development

Bingruo Wu, Brian Wu, Sonia Benkaci, Lijie Shi, Pengfei Lu, Taeju Park, Bernice E. Morrow, Yidong Wang, Bin Zhou

J Am Heart Assoc. 2023 Sep 19; 12(18): e029683. Published online 2023 Sep 13. doi: 10.1161/JAHA.123.029683

PMCID:: PMC10547300

Abstract Article PDF–41M

Select item 91062912.

Developmental dynamics of the neural crest–mesenchymal axis in creating the thymic microenvironment

Adam E. Handel, Stanley Cheuk, Fatima Dhalla, Stefano Maio, Tania Hübscher, Ioanna Rota, Mary E. Deadman, Olov Ekwall, Matthias Lütolf, Kenneth Weinberg, Georg Holländer

Sci Adv. 2022 May; 8(19): eabm9844. Published online 2022 May 13. doi: 10.1126/sciadv.abm9844

PMCID:: PMC9106291

Abstract Article PDF–7.6M

Select item 90292383.

Crk and Crkl have shared functions in neural crest cells for cardiac outflow tract septation and vascular smooth muscle differentiation

Lijie Shi, Silvia E Racedo, Alexander Diacou, Taeju Park, Bin Zhou, Bernice E Morrow

Hum Mol Genet. 2022 Apr 15; 31(8): 1197–1215. Published online 2021 Oct 23. doi: 10.1093/hmg/ddab313

PMCID:: PMC9029238

Abstract Article PDF–3.6M

Select item 82775744.

Mechanism of disease and therapeutic rescue of Dok7 congenital myasthenia

Julien Oury, Wei Zhang, Nadia Leloup, Akiko Koide, Alexis D. Corrado, Gayatri Ketavarapu, Takamitsu Hattori, Shohei Koide, Steven J. Burden

Nature. 2021; 595(7867): 404–408. Published online 2021 Jun 23. doi: 10.1038/s41586-021-03672-3

PMCID:: PMC8277574

Abstract Article PDF–6.6M

Select item 81697095.

Heterozygosity of murine Crkl does not recapitulate behavioral dimensions of human 22q11.2 hemizygosity

Takahira Yamauchi, Gina Kang, Noboru Hiroi

Genes Brain Behav. Author manuscript; available in PMC 2021 Jun 5.

Published in final edited form as: Genes Brain Behav. 2021 Jun; 20(5): e12719. Published online 2020 Dec 10. doi: 10.1111/gbb.12719

PMCID:: PMC8169709

Abstract Article PDF–603K

Select item 79831566.

IL-7-induced phosphorylation of the adaptor Crk-like and other targets

Francesca B. Aiello, Tad Guszczynski, Wenqing Li, Julie A. Hixon, Qiong Jiang, Deborah L. Hodge, Tania Massignan, Chiara Di Lisio, Anand Merchant, Antonio D. Procopio, Valentina Bonetto, Scott K. Durum

Cell Signal. Author manuscript; available in PMC 2021 Mar 22.

Published in final edited form as: Cell Signal. 2018 Jul; 47: 131–141. Published online 2018 Mar 24. doi: 10.1016/j.cellsig.2018.03.008

PMCID:: PMC7983156

Abstract Article PDF–1.7M

Select item 79387707.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 70103178.

Essential role of the Crk family-dosage in DiGeorge-like anomaly and metabolic homeostasis

Akira Imamoto, Sewon Ki, Leiming Li, Kazunari Iwamoto, Venkat Maruthamuthu, John Devany, Ocean Lu, Tomomi Kanazawa, Suxiang Zhang, Takuji Yamada, Akiyoshi Hirayama, Shinji Fukuda, Yutaka Suzuki, Mariko Okada

Life Sci Alliance. 2020 Feb; 3(2): e201900635. Published online 2020 Feb 10. doi: 10.26508/lsa.201900635

PMCID:: PMC7010317

Abstract Article PDF–3.6M

Select item 66023009.

New roles for the de-ubiquitylating enzyme OTUD4 in an RNA–protein network and RNA granules

Richa Das, Lukas Schwintzer, Stanislav Vinopal, Eva Aguado Roca, Marc Sylvester, Ana-Maria Oprisoreanu, Susanne Schoch, Frank Bradke, Meike Broemer

J Cell Sci. 2019 Jun 15; 132(12): jcs229252. Published online 2019 Jun 17. doi: 10.1242/jcs.229252

PMCID:: PMC6602300

Abstract Article

Select item 633331710.

Crk adaptor proteins mediate actin-dependent T cell migration and mechanosensing induced by the integrin LFA-1

Nathan H. Roy, Joanna L. MacKay, Tanner F. Robertson, Daniel A. Hammer, Janis K. Burkhardt

Sci Signal. Author manuscript; available in PMC 2019 Jun 11.

Published in final edited form as: Sci Signal. 2018 Dec 11; 11(560): eaat3178. Published online 2018 Dec 11. doi: 10.1126/scisignal.aat3178

PMCID:: PMC6333317

Abstract Article PDF–3.2M

Select item 626277711.

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow

Hui-yuan Tseng, Anna V. Samarelli, Patricia Kammerer, Sarah Scholze, Tilman Ziegler, Roland Immler, Roy Zent, Markus Sperandio, Charles R. Sanders, Reinhard Fässler, Ralph T. Böttcher

J Cell Sci. 2018 Nov 15; 131(22): jcs218214. Published online 2018 Nov 21. doi: 10.1242/jcs.218214

PMCID:: PMC6262777

Abstract Article

Select item 624418312.

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells

Sunyuan Zhang, Nicholas A. Williamson, Marie A. Bogoyevitch

Sci Data. 2018; 5: 180262. Published online 2018 Nov 20. doi: 10.1038/sdata.2018.262

PMCID:: PMC6244183

Abstract Article PDF–753K

Select item 581825113.

Crk proteins transduce FGF signaling to promote lens fiber cell elongation

Tamica N Collins, Yingyu Mao, Hongge Li, Michael Bouaziz, Angela Hong, Gen-Sheng Feng, Fen Wang, Lawrence A Quilliam, Lin Chen, Taeju Park, Tom Curran, Xin Zhang

eLife. 2018; 7: e32586. Published online 2018 Jan 23. doi: 10.7554/eLife.32586

PMCID:: PMC5818251

Abstract Article PDF–8.2M

Select item 555973114.

Genetic Drivers of Kidney Defects in the DiGeorge Syndrome

E. Lopez-Rivera, Y.P. Liu, M. Verbitsky, B.R. Anderson, V.P. Capone, E.A. Otto, Z. Yan, A. Mitrotti, J. Martino, N.J. Steers, D.A. Fasel, K. Vukojevic, R. Deng, S.E. Racedo, Q. Liu, M. Werth, R. Westland, A. Vivante, G.S. Makar, M. Bodria, M.G. Sampson, C.E. Gillies, V. Vega-Warner, M. Maiorana, D.S. Petrey, B. Honig, V.J. Lozanovski, R. Salomon, L. Heidet, W. Carpentier, D. Gaillard, A. Carrea, L. Gesualdo, D. Cusi, C. Izzi, F. Scolari, J.A.E. van Wijk, A. Arapovic, M. Saraga-Babic, M. Saraga, N. Kunac, A. Samii, D.M. McDonald-McGinn, T.B. Crowley, E.H. Zackai, D. Drozdz, M. Miklaszewska, M. Tkaczyk, P. Sikora, M. Szczepanska, M. Mizerska-Wasiak, G. Krzemien, A. Szmigielska, M. Zaniew, J.M. Darlow, P. Puri, D. Barton, E. Casolari, S.L. Furth, B.A. Warady, Z. Gucev, H. Hakonarson, H. Flogelova, V. Tasic, A. Latos-Bielenska, A. Materna-Kiryluk, L. Allegri, C.S. Wong, I.A. Drummond, V. D’Agati, A. Imamoto, J.M. Barasch, F. Hildebrandt, K. Kiryluk, R.P. Lifton, B.E. Morrow, C. Jeanpierre, V.E. Papaioannou, G.M. Ghiggeri, A.G. Gharavi, N. Katsanis, S. Sanna-Cherchi

N Engl J Med. Author manuscript; available in PMC 2017 Aug 17.

Published in final edited form as: N Engl J Med. 2017 Feb 23; 376(8): 742–754. Published online 2017 Jan 25. doi: 10.1056/NEJMoa1609009