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Select item 109176601.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 106462132.

Uterine Nodal expression supports maternal immunotolerance and establishment of the FOXP3⁺ regulatory T cell population during the preimplantation period

Sarah Yull, Shiva Shafiei, Craig B. Park, Parinaz Kazemi, Emily B. Tiemann, Marie-Hélène Godin Pagé, Daniel Dufort

Front Immunol. 2023; 14: 1276979. Published online 2023 Oct 30. doi: 10.3389/fimmu.2023.1276979

PMCID:: PMC10646213

Abstract Article PDF–3.3M

Select item 105133243.

Bicc1 ribonucleoprotein complexes specifying organ laterality are licensed by ANKS6-induced structural remodeling of associated ANKS3

Benjamin Rothé, Yayoi Ikawa, Zhidian Zhang, Takanobu A. Katoh, Eriko Kajikawa, Katsura Minegishi, Sai Xiaorei, Simon Fortier, Matteo Dal Peraro, Hiroshi Hamada, Daniel B. Constam

PLoS Biol. 2023 Sep; 21(9): e3002302. Published online 2023 Sep 21. doi: 10.1371/journal.pbio.3002302

PMCID:: PMC10513324

Abstract Article PDF–3.1M

Select item 105021534.

Time space and single-cell resolved tissue lineage trajectories and laterality of body plan at gastrulation

Ran Wang, Xianfa Yang, Jiehui Chen, Lin Zhang, Jonathan A. Griffiths, Guizhong Cui, Yingying Chen, Yun Qian, Guangdun Peng, Jinsong Li, Liantang Wang, John C. Marioni, Patrick P. L. Tam, Naihe Jing

Nat Commun. 2023; 14: 5675. Published online 2023 Sep 14. doi: 10.1038/s41467-023-41482-5

PMCID:: PMC10502153

Abstract Article PDF–8.1M

Select item 101668365.

A genetic and developmental biological approach for a family with complex congenital heart diseases—evidence of digenic inheritance

Yu Yoshida, Keiko Uchida, Kazuki Kodo, Reina Ishizaki-Asami, Jun Maeda, Yoshinori Katsumata, Shinsuke Yuasa, Keiichi Fukuda, Kenjiro Kosaki, Yusuke Watanabe, Osamu Nakagawa, Hiroyuki Yamagishi

Front Cardiovasc Med. 2023; 10: 1135141. Published online 2023 Apr 25. doi: 10.3389/fcvm.2023.1135141

PMCID:: PMC10166836

Abstract Article PDF–18M

Select item 95344136.

The RNA helicase DDX6 controls early mouse embryogenesis by repressing aberrant inhibition of BMP signaling through miRNA-mediated gene silencing

Jessica Kim, Masafumi Muraoka, Hajime Okada, Atsushi Toyoda, Rieko Ajima, Yumiko Saga

PLoS Genet. 2022 Oct; 18(10): e1009967. Published online 2022 Oct 5. doi: 10.1371/journal.pgen.1009967

PMCID:: PMC9534413

Abstract Article PDF–3.8M

Select item 90839127.

Spectrum of Genetic Variants in a Cohort of 37 Laterality Defect Cases

Dinu Antony, Elif Gulec Yilmaz, Alper Gezdirici, Lennart Slagter, Zeineb Bakey, Helen Bornaun, Ibrahim Cansaran Tanidir, Tran Van Dinh, Han G. Brunner, Peter Walentek, Sebastian J. Arnold, Rolf Backofen, Miriam Schmidts

Front Genet. 2022; 13: 861236. Published online 2022 Apr 13. doi: 10.3389/fgene.2022.861236

PMCID:: PMC9083912

Abstract Article PDF–1.7M

Select item 81713818.

Rab7-Mediated Endocytosis Establishes Patterning of Wnt Activity through Inactivation of Dkk Antagonism

Nobuyuki Kawamura, Katsuyoshi Takaoka, Hiroshi Hamada, Anna-Katerina Hadjantonakis, Ge-Hong Sun-Wada, Yoh Wada

Cell Rep. Author manuscript; available in PMC 2021 Jun 2.

Published in final edited form as: Cell Rep. 2020 Jun 9; 31(10): 107733. doi: 10.1016/j.celrep.2020.107733

PMCID:: PMC8171381

Abstract Article PDF–1.3M

Select item 79463779.

Deciphering epiblast lumenogenesis reveals proamniotic cavity control of embryo growth and patterning

Yung Su Kim, Rui Fan, Ludmila Kremer, Nannette Kuempel-Rink, Karina Mildner, Dagmar Zeuschner, Liesbeth Hekking, Martin Stehling, Ivan Bedzhov

Sci Adv. 2021 Mar; 7(11): eabe1640. Published online 2021 Mar 10. doi: 10.1126/sciadv.abe1640

PMCID:: PMC7946377

Abstract Article PDF–5.3M

Select item 772450410.

Two-Color In Situ Hybridization of Whole-Mount Mouse Embryos

Kristin K. Biris, Terry P. Yamaguchi

Methods Mol Biol. Author manuscript; available in PMC 2020 Dec 9.

Published in final edited form as: Methods Mol Biol. 2014; 1092: 17–30. doi: 10.1007/978-1-60327-292-6_2

PMCID:: PMC7724504

Abstract Article PDF–485K

Select item 746772211.

Cdon mutation and fetal alcohol converge on Nodal signaling in a mouse model of holoprosencephaly

Mingi Hong, Annabel Christ, Anna Christa, Thomas E Willnow, Robert S Krauss

eLife. 2020; 9: e60351. Published online 2020 Sep 2. doi: 10.7554/eLife.60351

PMCID:: PMC7467722

Abstract Article PDF–2.9M

Select item 737583212.

Role of Ca²⁺ transients at the node of the mouse embryo in breaking of left-right symmetry

Katsutoshi Mizuno, Kei Shiozawa, Takanobu A. Katoh, Katsura Minegishi, Takahiro Ide, Yayoi Ikawa, Hiromi Nishimura, Katsuyoshi Takaoka, Takeshi Itabashi, Atsuko H. Iwane, Junichi Nakai, Hidetaka Shiratori, Hiroshi Hamada

Sci Adv. 2020 Jul; 6(30): eaba1195. Published online 2020 Jul 22. doi: 10.1126/sciadv.aba1195

PMCID:: PMC7375832

Abstract Article PDF–1.0M

Select item 730817313.

Basement membrane remodelling regulates mouse embryogenesis

Christos Kyprianou, Neophytos Christodoulou, Russell S. Hamilton, Wallis Nahaboo, Diana Suarez Boomgaard, Gianluca Amadei, Isabelle Migeotte, Magdalena Zernicka-Goetz

Nature. Author manuscript; available in PMC 2020 Nov 6.

Published in final edited form as: Nature. 2020 Jun; 582(7811): 253–258. Published online 2020 May 6. doi: 10.1038/s41586-020-2264-2

PMCID:: PMC7308173

Abstract Article PDF–8.2M

Select item 729781214.

Mutation of LRP1 in cardiac neural crest cells causes congenital heart defects by perturbing outflow lengthening

Jiuann-Huey I. Lin, Timothy N. Feinstein, Anupma Jha, Jacob T. McCleary, Juan Xu, Angelo B. Arrigo, Grace Rong, Lindsey M. Maclay, Taylor Ridge, XinXiu Xu, Cecilia W. Lo

Commun Biol. 2020; 3: 312. Published online 2020 Jun 16. doi: 10.1038/s42003-020-1035-9