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Items: 1 to 20 of 96

1.
TREM2 macrophages drive NK cell paucity and dysfunction in lung cancer
Matthew D. Park, Ivan Reyes-Torres, Jessica LeBerichel, Pauline Hamon, Nelson M. LaMarche, Samarth Hegde, Meriem Belabed, Leanna Troncoso, John A. Grout, Assaf Magen, Etienne Humblin, Achuth Nair, Martina Molgora, Jinchao Hou, Jenna H. Newman, Adam M. Farkas, Andrew M. Leader, Travis Dawson, Darwin D’Souza, Steven Hamel, Alfonso Rodriguez Sanchez-Paulete, Barbara Maier, Jerome C. Martin, Alice O. Kamphorst, Ephraim Kenigsberg, Maria Casanova-Acebes, Nina Bhardwaj, Amir Horowitz, Brian D. Brown, Lucas Ferrari De Andrade, Marco Colonna, Thomas U. Marron, Miriam Merad
Nat Immunol. Author manuscript; available in PMC 2024 May 12.
Published in final edited form as: Nat Immunol. 2023 May; 24(5): 792–801. Published online 2023 Apr 20. doi: 10.1038/s41590-023-01475-4
PMCID:
PMC11088947
AbstractArticlePDF–2.7M
2.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
3.
The Basophil IL-18 Receptor Precisely Regulates the Host Immune Response and Malaria-Induced Intestinal Permeability and Alters Parasite Transmission to Mosquitoes without Effect on Gametocytemia
Erinn L. Donnelly, Nora Céspedes, Gretchen Hansten, Delaney Wagers, Anna M. Briggs, Casey Lowder, Joseph Schauer, Lori Haapanen, Judy Van de Water, Shirley Luckhart
Immunohorizons. Author manuscript; available in PMC 2023 Mar 1.
Published in final edited form as: Immunohorizons. 2022 Aug 19; 6(8): 630–641. Published online 2022 Aug 19. doi: 10.4049/immunohorizons.2200057
PMCID:
PMC9977167
AbstractArticlePDF–1.3M
4.
IL18 Receptor Signaling Inhibits Intratumoral CD8+ T-Cell Migration in a Murine Pancreatic Cancer Model
Elena Nasiri, Malte Student, Katrin Roth, Nadya Siti Utami, Magdalena Huber, Malte Buchholz, Thomas M. Gress, Christian Bauer
Cells. 2023 Feb; 12(3): 456. Published online 2023 Jan 31. doi: 10.3390/cells12030456
PMCID:
PMC9913970
AbstractArticlePDF–2.9M
5.
Differential IL18 signaling via IL18 receptor and Na-Cl co-transporter discriminating thermogenesis and glucose metabolism regulation
Xian Zhang, Songyuan Luo, Minjie Wang, Qiongqiong Cao, Zhixin Zhang, Qin Huang, Jie Li, Zhiyong Deng, Tianxiao Liu, Cong-Lin Liu, Mathilde Meppen, Amelie Vromman, Richard A. Flavell, Gökhan S. Hotamışlıgil, Jian Liu, Peter Libby, Zhangsuo Liu, Guo-Ping Shi
Nat Commun. 2022; 13: 7582. Published online 2022 Dec 8. doi: 10.1038/s41467-022-35256-8
PMCID:
PMC9732325
AbstractArticlePDF–8.5M
6.
The Transcription Factor PLZF is Necessary for the Development and Function of Mouse Basophils
Sai Zhang, Joshua A. Vieth, Agata Krzyzanowska, Everett K. Henry, Lisa K. Denzin, Mark C. Siracusa, Derek B. Sant’Angelo
J Immunol. Author manuscript; available in PMC 2022 Nov 30.
Published in final edited form as: J Immunol. 2019 Sep 1; 203(5): 1230–1241. Published online 2019 Jul 31. doi: 10.4049/jimmunol.1900068
PMCID:
PMC9710206
AbstractArticlePDF–1.4M
7.
IL-18/IL-18R Signaling Is Dispensable for ILC Development But Constrains the Growth of ILCP/ILCs
Mengying Xie, Mingying Zhang, Mengyuan Dai, Shan Yue, Zhao Li, Ju Qiu, Chenqi Lu, Wei Xu
Front Immunol. 2022; 13: 923424. Published online 2022 Jul 8. doi: 10.3389/fimmu.2022.923424
PMCID:
PMC9304618
AbstractArticlePDF–15M
8.
Cytotoxic CD4+ T cells driven by T-cell intrinsic IL-18R/MyD88 signaling predominantly infiltrate Trypanosoma cruzi-infected hearts
Carlos-Henrique D Barbosa, Fábio B Canto, Ariel Gomes, Layza M Brandao, Jéssica R Lima, Guilherme A Melo, Alessandra Granato, Eula GA Neves, Walderez O Dutra, Ana-Carolina Oliveira, Alberto Nóbrega, Maria Bellio
eLife. 2022; 11: e74636. Published online 2022 Jun 7. doi: 10.7554/eLife.74636
PMCID:
PMC9236613
AbstractArticlePDF–12M
9.
Differential Regulation of Transcription Factor T-bet Induction during NK Cell Development and T Helper-1 Cell Differentiation
Difeng Fang, Kairong Cui, Yaqiang Cao, Mingzhu Zheng, Takeshi Kawabe, Gangqing Hu, Jaspal S. Khillan, Dan Li, Chao Zhong, Dragana Jankovic, Alan Sher, Keji Zhao, Jinfang Zhu
Immunity. Author manuscript; available in PMC 2023 Apr 12.
Published in final edited form as: Immunity. 2022 Apr 12; 55(4): 639–655.e7. Published online 2022 Apr 4. doi: 10.1016/j.immuni.2022.03.005
PMCID:
PMC9059963
AbstractArticlePDF–1.9M
10.
IL-18R-mediated HSC quiescence and MLKL-dependent cell death limit hematopoiesis during infection-induced shock
Jennifer E. Howard, Julianne N.P. Smith, Gabrielle Fredman, Katherine C. MacNamara
Stem Cell Reports. 2021 Dec 14; 16(12): 2887–2899. Published online 2021 Nov 18. doi: 10.1016/j.stemcr.2021.10.011
PMCID:
PMC8693653
AbstractArticlePDF–2.9M
11.
Adoptive immunotherapy with transient anti-CD4 treatment enhances anti-tumor response by increasing IL-18Rαhi CD8+ T cells
Seon-Hee Kim, Eunjung Cho, Yu I. Kim, Chungyong Han, Beom K. Choi, Byoung S. Kwon
Nat Commun. 2021; 12: 5314. Published online 2021 Sep 7. doi: 10.1038/s41467-021-25559-7
PMCID:
PMC8423719
AbstractArticlePDF–3.7M
12.
Expression of Nutrient Transporters on NK Cells During Murine Cytomegalovirus Infection Is MyD88-Dependent
Abrar Ul Haq Khan, Saeedah Musaed Almutairi, Alaa Kassim Ali, Rosalba Salcedo, C. Andrew Stewart, Lisheng Wang, Seung-Hwan Lee
Front Immunol. 2021; 12: 654225. Published online 2021 May 3. doi: 10.3389/fimmu.2021.654225
PMCID:
PMC8177011
AbstractArticlePDF–1.4M
13.
IL-18BP is a secreted immune checkpoint and barrier to IL-18 immunotherapy
Ting Zhou, William Damsky, Orr-El Weizman, Meaghan K. McGeary, K. Patricia Hartmann, Connor E. Rosen, Suzanne Fischer, Ruaidhri Jackson, Richard A. Flavell, Jun Wang, Miguel F. Sanmamed, Marcus W. Bosenberg, Aaron M. Ring
Nature. Author manuscript; available in PMC 2020 Dec 24.
Published in final edited form as: Nature. 2020 Jul; 583(7817): 609–614. Published online 2020 Jun 24. doi: 10.1038/s41586-020-2422-6
PMCID:
PMC7381364
AbstractArticlePDF–6.7M
14.
IL18 signaling promotes homing of mature Tregs into the thymus
Cristina Peligero-Cruz, Tal Givony, Arnau Sebé-Pedrós, Jan Dobeš, Noam Kadouri, Shir Nevo, Francesco Roncato, Ronen Alon, Yael Goldfarb, Jakub Abramson
eLife. 2020; 9: e58213. Published online 2020 Jul 20. doi: 10.7554/eLife.58213
PMCID:
PMC7371425
AbstractArticlePDF–1.2M
15.
Enteric Nervous System-Derived IL-18 Orchestrates Mucosal Barrier Immunity
Abigail Jarret, Ruaidhrí Jackson, Coco Duizer, Marc E. Healy, Jun Zhao, Joseph M. Rone, Piotr Bielecki, Esen Sefik, Manolis Roulis, Tyler Rice, Kisha N. Sivanathan, Ting Zhou, Angel G. Solis, Hanna Honcharova-Biletska, Karelia Vélez, Saskia Hartner, Jun Siong Low, Rihao Qu, Marcel R. de Zoete, Noah W. Palm, Aaron M. Ring, Achim Weber, Andreas E. Moor, Yuval Kluger, Roni Nowarski, Richard A. Flavell
Cell. Author manuscript; available in PMC 2021 Jan 9.
Published in final edited form as: Cell. 2020 Jan 9; 180(1): 50–63.e12. doi: 10.1016/j.cell.2019.12.016
PMCID:
PMC7339937
AbstractArticlePDF–1.5M
16.
Insights into the Role of Innate Immunity in Cervicovaginal Papillomavirus Infection from Studies Using Gene-Deficient Mice
Carolina Scagnolari, Fabiana Cannella, Alessandra Pierangeli, Rebecca Mellinger Pilgrim, Guido Antonelli, Dayana Rowley, Margaret Wong, Simon Best, Deyin Xing, Richard B. S. Roden, Raphael Viscidi
J Virol. 2020 Jun; 94(12): e00087-20. Prepublished online 2020 Apr 15. Published online 2020 Jun 1. doi: 10.1128/JVI.00087-20
PMCID:
PMC7307098
AbstractArticlePDF–7.9M
17.
Platelets Fuel the Inflammasome Activation of Innate Immune Cells
Verena Rolfes, Lucas Secchim Ribeiro, Ibrahim Hawwari, Lisa Böttcher, Nathalia Rosero, Salie Maasewerd, Marina Lima Silva Santos, Tomasz Próchnicki, Camila Meirelles de Souza Silva, Carlos Wagner de Souza Wanderley, Maximilian Rothe, Susanne V. Schmidt, H. James Stunden, Damien Bertheloot, Magali Noval Rivas, Cor Jesus Fontes, Luzia Helena Carvalho, Fernando Queiroz Cunha, Eicke Latz, Moshe Arditi, Bernardo Simoes Franklin
Cell Rep. 2020 May 12; 31(6): 107615. Published online 2020 May 12. doi: 10.1016/j.celrep.2020.107615
PMCID:
PMC7225754
AbstractArticle
18.
Inhibition of the IL-18 Receptor Signaling Pathway Ameliorates Disease in a Murine Model of Rheumatoid Arthritis
Yuji Nozaki, Jinhai Ri, Kenji Sakai, Kaoru Niki, Koji Kinoshita, Masanori Funauchi, Itaru Matsumura
Cells. 2020 Jan; 9(1): 11. Published online 2019 Dec 18. doi: 10.3390/cells9010011
PMCID:
PMC7017073
AbstractArticlePDF–1.9M
19.
Inflammasome activation triggers blood clotting and host death through pyroptosis
Congqing Wu, Wei Lu, Yan Zhang, Guoying Zhang, Xuyan Shi, Yohei Hisada, Steven P. Grover, Xinyi Zhang, Lan Li, Binggang Xiang, Jumei Shi, Xiang-An Li, Alan Daugherty, Susan S. Smyth, Daniel Kirchhofer, Toshihiko Shiroishi, Feng Shao, Nigel Mackman, Yinan Wei, Zhenyu Li
Immunity. Author manuscript; available in PMC 2020 Jun 18.
Published in final edited form as: Immunity. 2019 Jun 18; 50(6): 1401–1411.e4. Published online 2019 May 7. doi: 10.1016/j.immuni.2019.04.003
PMCID:
PMC6791531
ArticlePDF–1.4M
20.
Cytomegalovirus infection drives avidity selection of natural killer cells
Nicholas M. Adams, Clair D. Geary, Endi K. Santosa, Dianne Lumaquin, Jean-Benoît Le Luduec, Rosa Sottile, Kattria van der Ploeg, Joy Hsu, Benjamin M. Whitlock, Benjamin T. Jackson, Orr-El Weizman, Morgan Huse, Katharine C. Hsu, Joseph C. Sun
Immunity. Author manuscript; available in PMC 2020 Jun 18.
Published in final edited form as: Immunity. 2019 Jun 18; 50(6): 1381–1390.e5. Published online 2019 May 15. doi: 10.1016/j.immuni.2019.04.009
PMCID:
PMC6614060
AbstractArticlePDF–1.4M

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