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Items: 1 to 20 of 57

1.
Mutations in the Vicinity of the IRAK3 Guanylate Cyclase Center Impact Its Subcellular Localization and Ability to Modulate Inflammatory Signaling in Immortalized Cell Lines
Ilona Turek, Trang H. Nguyen, Charles Galea, Isaiah Abad, Lubna Freihat, David T. Manallack, Tony Velkov, Helen Irving
Int J Mol Sci. 2023 May; 24(10): 8572. Published online 2023 May 10. doi: 10.3390/ijms24108572
PMCID:
PMC10217915
AbstractArticlePDF–2.9M
2.
IRAK-M has effects in regulation of lung epithelial inflammation
Jia Li, Zhoude Zheng, Yi Liu, Hongbing Zhang, Youming Zhang, Jinming Gao
Respir Res. 2023; 24: 103. Published online 2023 Apr 7. doi: 10.1186/s12931-023-02406-5
PMCID:
PMC10082527
AbstractArticlePDF–1.7M
3.
Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity
Martin Golkowski, Andrea Lius, Tanmay Sapre, Ho-Tak Lau, Taylor Moreno, Dustin J. Maly, Shao-En Ong
Mol Cell. Author manuscript; available in PMC 2023 Apr 4.
Published in final edited form as: Mol Cell. 2023 Mar 2; 83(5): 803–818.e8. Published online 2023 Feb 2. doi: 10.1016/j.molcel.2023.01.015
PMCID:
PMC10072906
AbstractArticlePDF–4.2M
4.
IL-1 receptor–associated kinase-3 acts as an immune checkpoint in myeloid cells to limit cancer immunotherapy
Gürcan Tunalı, Marta Rúbies Bedós, Divya Nagarajan, Patrik Fridh, Irineos Papakyriacou, Yumeng Mao
J Clin Invest. 2023 Apr 3; 133(7): e161084. Published online 2023 Apr 3. doi: 10.1172/JCI161084
PMCID:
PMC10065081
AbstractArticlePDF–10M
5.
Changes in plasma IRAK-M in patients with prediabetes and its relationship with related metabolic indexes: a cross-sectional study
Xiaomin Xie, Guirong Bai, Li Zhang, Huili Liu, Dan Qiang, Ling Li
J Int Med Res. 2022 Aug; 50(8): 03000605221111275. Published online 2022 Aug 30. doi: 10.1177/03000605221111275
PMCID:
PMC9437484
AbstractArticlePDF–636K
6.
Modulation of Inflammatory Cytokine Production in Human Monocytes by cGMP and IRAK3
Trang H. Nguyen, Anna Axell, Ilona Turek, Bree Wright, Terri Meehan-Andrews, Helen R. Irving
Int J Mol Sci. 2022 Mar; 23(5): 2552. Published online 2022 Feb 25. doi: 10.3390/ijms23052552
PMCID:
PMC8909980
AbstractArticlePDF–1.6M
7.
A systematic review and meta-analyses of interleukin-1 receptor associated kinase 3 (IRAK3) action on inflammation in in vivo models for the study of sepsis
Trang H. Nguyen, Ilona Turek, Terri Meehan-Andrews, Anita Zacharias, Helen R. Irving
PLoS One. 2022; 17(2): e0263968. Published online 2022 Feb 15. doi: 10.1371/journal.pone.0263968
PMCID:
PMC8846508
AbstractArticlePDF–3.6M
8.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
9.
Dimeric Structure of the Pseudokinase IRAK3 Suggests an Allosteric Mechanism for Negative Regulation
Sven M. Lange, Marina I. Nelen, Philip Cohen, Yogesh Kulathu
Structure. 2021 Mar 4; 29(3): 238–251.e4. doi: 10.1016/j.str.2020.11.004
PMCID:
PMC7955167
AbstractArticle
10.
Knockdown of Circ_SLC39A8 protects against the progression of osteoarthritis by regulating miR-591/IRAK3 axis
Jizhe Yu, Yushuang Qin, Naxin Zhou
J Orthop Surg Res. 2021; 16: 170. Published online 2021 Mar 3. doi: 10.1186/s13018-021-02323-7
PMCID:
PMC7927261
AbstractArticlePDF–2.9M
11.
Kinase Interaction Network Expands Functional and Disease Roles of Human Kinases
Marija Buljan, Rodolfo Ciuffa, Audrey van Drogen, Anton Vichalkovski, Martin Mehnert, George Rosenberger, Sohyon Lee, Markku Varjosalo, Lucia Espona Pernas, Vincent Spegg, Berend Snijder, Ruedi Aebersold, Matthias Gstaiger
Mol Cell. 2020 Aug 6; 79(3): 504–520.e9. doi: 10.1016/j.molcel.2020.07.001
PMCID:
PMC7427327
AbstractArticle
12.
Epithelial-derived gasdermin D mediates nonlytic IL-1β release during experimental colitis
Katarzyna Bulek, Junjie Zhao, Yun Liao, Nitish Rana, Daniele Corridoni, Agne Antanaviciute, Xing Chen, Han Wang, Wen Qian, William A. Miller-Little, Shadi Swaidani, Fangqiang Tang, Belinda B. Willard, Keith McCrae, Zizhen Kang, George R. Dubyak, Fabio Cominelli, Alison Simmons, Theresa T. Pizarro, Xiaoxia Li
J Clin Invest. 2020 Aug 3; 130(8): 4218–4234. Published online 2020 Jun 29. doi: 10.1172/JCI138103
PMCID:
PMC7410065
AbstractArticlePDF–15M
13.
Induction of IRAK-M in melanoma induces caspase-3 dependent apoptosis by reducing TRAF6 and calpastatin levels
Degui Geng, Nicholas Ciavattone, Jackline Joy Lasola, Rojesh Shrestha, Amelia Sanchez, Jitao Guo, Alexandra Vlk, Rania Younis, Lucy Wang, Alex J. Brown, Yuji Zhang, Cruz Velasco-Gonzalez, Aik-Choon Tan, Eduardo Davila
Commun Biol. 2020; 3: 306. Published online 2020 Jun 12. doi: 10.1038/s42003-020-1033-y
PMCID:
PMC7293221
AbstractArticlePDF–2.0M
14.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
15.
RNF152 positively regulates TLR/IL‐1R signaling by enhancing MyD88 oligomerization
Mei‐Guang Xiong, Zhi‐Sheng Xu, Yu‐Hui Li, Su‐Yun Wang, Yan‐Yi Wang, Yong Ran
EMBO Rep. 2020 Mar 4; 21(3): e48860. Published online 2020 Jan 13. doi: 10.15252/embr.201948860
PMCID:
PMC7054668
AbstractArticlePDF–1.2M
16.
IRAK3 modulates downstream innate immune signalling through its guanylate cyclase activity
L. A. Freihat, J. I. Wheeler, A. Wong, I. Turek, D. T. Manallack, H. R. Irving
Sci Rep. 2019; 9: 15468. Published online 2019 Oct 29. doi: 10.1038/s41598-019-51913-3
PMCID:
PMC6820782
AbstractArticlePDF–1.8M
17.
TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile
Karen Dendoncker, Steven Timmermans, Jolien Vandewalle, Melanie Eggermont, Joanna Lempiäinen, Evelien Van Hamme, Sylviane Dewaele, Sofie Vandevyver, Marlies Ballegeer, Jolien Souffriau, Lise Van Wyngene, Kelly Van Looveren, Tineke Vanderhaeghen, Rudi Beyaert, Karolien De Bosscher, Jorma J. Palvimo, Marc Van Montagu, Claude Libert
Proc Natl Acad Sci U S A. 2019 Jun 25; 116(26): 12942–12951. Published online 2019 Jun 10. doi: 10.1073/pnas.1821565116
Correction in:
Proc Natl Acad Sci U S A. 2019 Jul 30; 116(31): 15745.
PMCID:
PMC6600915
AbstractArticlePDF–1.7M
18.
IRAK-M associates with susceptibility to adult-onset asthma and promotes chronic airway inflammation
Yi Liu, Mingqiang Zhang, Lili Lou, Lun Li, Youming Zhang, Wei Chen, Weixun Zhou, Yan Bai, Jinming Gao
J Immunol. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: J Immunol. 2019 Feb 1; 202(3): 899–911. Published online 2019 Jan 7. doi: 10.4049/jimmunol.1800712
PMCID:
PMC6344301
AbstractArticlePDF–2.0M
19.
TLR-stimulated IRAKM activates caspase-8 inflammasome in microglia and promotes neuroinflammation
Cun-Jin Zhang, Meiling Jiang, Hao Zhou, Weiwei Liu, Chenhui Wang, Zizhen Kang, Bing Han, Quanri Zhang, Xing Chen, Jianxin Xiao, Amanda Fisher, William J. Kaiser, Masanori A. Murayama, Yoichiro Iwakura, Ji Gao, Julie Carman, Ashok Dongre, George Dubyak, Derek W. Abbott, Fu-Dong Shi, Richard M. Ransohoff, Xiaoxia Li
J Clin Invest. 2018 Dec 3; 128(12): 5399–5412. Published online 2018 Oct 29. doi: 10.1172/JCI121901
PMCID:
PMC6264724
AbstractArticlePDF–13M
20.
Histone Interaction Landscapes Visualized by Crosslinking Mass Spectrometry in Intact Cell Nuclei
Domenico Fasci, Hugo van Ingen, Richard A. Scheltema, Albert J. R. Heck
Mol Cell Proteomics. 2018 Oct; 17(10): 2018–2033. Published online 2018 Jul 18. doi: 10.1074/mcp.RA118.000924
PMCID:
PMC6166682
AbstractArticlePDF–3.8M

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