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Items: 1 to 20 of 36

1.
The Role of Phosphatidylethanolamine N-Methyltransferase (PEMT) and Its Waist-Hip-Ratio-Associated Locus rs4646404 in Obesity-Related Metabolic Traits and Liver Disease
Chang Sun, David J. F. Holstein, Natalia Garcia-Cubero, Yusef Moulla, Christine Stroh, Arne Dietrich, Michael R. Schön, Daniel Gärtner, Tobias Lohmann, Miriam Dressler, Michael Stumvoll, Matthias Blüher, Peter Kovacs, Esther Guiu-Jurado
Int J Mol Sci. 2023 Dec; 24(23): 16850. Published online 2023 Nov 28. doi: 10.3390/ijms242316850
PMCID:
PMC10706059
AbstractArticlePDF–2.4M
2.
Hepatocyte-derived DPP4 regulates portal GLP-1 bioactivity, modulates glucose production, and when absent influences NAFLD progression
Natasha A. Trzaskalski, Branka Vulesevic, My-Anh Nguyen, Natasha Jeraj, Evgenia Fadzeyeva, Nadya M. Morrow, Cassandra A.A. Locatelli, Nicole Travis, Antonio A. Hanson, Julia R.C. Nunes, Conor O’Dwyer, Jelske N. van der Veen, Ilka Lorenzen-Schmidt, Rick Seymour, Serena M. Pulente, Andrew C. Clément, Angela M. Crawley, René L. Jacobs, Mary-Anne Doyle, Curtis L. Cooper, Kyoung-Han Kim, Morgan D. Fullerton, Erin E. Mulvihill
JCI Insight. 2023 Jan 24; 8(2): e154314. Published online 2023 Jan 24. doi: 10.1172/jci.insight.154314
PMCID:
PMC9977314
AbstractArticlePDF–30M
3.
Phosphatidylethanolamine N-Methyltransferase Knockout Modulates Metabolic Changes in Aging Mice
Qishun Zhou, Fangrong Zhang, Jakob Kerbl-Knapp, Melanie Korbelius, Katharina Barbara Kuentzel, Nemanja Vujić, Alena Akhmetshina, Gerd Hörl, Margret Paar, Ernst Steyrer, Dagmar Kratky, Tobias Madl
Biomolecules. 2022 Sep; 12(9): 1270. Published online 2022 Sep 9. doi: 10.3390/biom12091270
PMCID:
PMC9496051
AbstractArticlePDF–26M
4.
Liver and brain differential expression of one-carbon metabolism genes during ontogenesis
Apolline Imbard, Leslie Schwendimann, Sophie Lebon, Pierre Gressens, Henk J. Blom, Jean-François Benoist
Sci Rep. 2021; 11: 21132. Published online 2021 Oct 26. doi: 10.1038/s41598-021-00311-9
PMCID:
PMC8548596
AbstractArticlePDF–1.3M
5.
Phospholipid methylation regulates muscle metabolic rate through Ca2+ transport efficiency
Anthony R.P. Verkerke, Patrick J. Ferrara, Chien-Te Lin, Jordan M. Johnson, Terence E. Ryan, J. Alan Maschek, Hiroaki Eshima, Christopher W. Paran, Brenton T. Laing, Piyarat Siripoksup, Trevor S. Tippetts, Edward J. Wentzler, Hu Huang, Espen. E. Spangenburg, Jeffrey J. Brault, Claudio J. Villanueva, Scott A. Summers, William L. Holland, James E. Cox, Dennis E. Vance, P. Darrell Neufer, Katsuhiko Funai
Nat Metab. Author manuscript; available in PMC 2020 May 13.
Published in final edited form as: Nat Metab. 2019 Sep; 1(9): 876–885. Published online 2019 Sep 16. doi: 10.1038/s42255-019-0111-2
PMCID:
PMC7218817
AbstractArticlePDF–1.9M
6.
Methyl-sensing nuclear receptor Liver Receptor Homolog-1 regulates mitochondrial function in mouse hepatocytes
Sungwoo Choi, Bingning Dong, Chih-Chun Janet Lin, Mi Jeong Heo, Kang Ho Kim, Zhen Sun, Martin Wagner, Jae Myoung Suh, Meng C. Wang, David D. Moore
Hepatology. Author manuscript; available in PMC 2021 Mar 1.
Published in final edited form as: Hepatology. 2020 Mar; 71(3): 1055–1069. Published online 2019 Dec 23. doi: 10.1002/hep.30884
PMCID:
PMC6987012
AbstractArticlePDF–1.6M
7.
Alternative splicing of UCP1 by non-cell-autonomous action of PEMT
Jordan M. Johnson, Anthony R.P. Verkerke, J. Alan Maschek, Patrick J. Ferrara, Chien-Te Lin, Kimberly A. Kew, P. Darrell Neufer, Irfan J. Lodhi, James E. Cox, Katsuhiko Funai
Mol Metab. 2020 Jan; 31: 55–66. Published online 2019 Nov 8. doi: 10.1016/j.molmet.2019.10.007
PMCID:
PMC6889607
AbstractArticlePDF–2.4M
8.
Impaired Hepatic Phosphatidylcholine Synthesis Leads to Cholestasis in Mice Challenged With a High‐Fat Diet
Sereana Wan, Folkert Kuipers, Rick Havinga, Hiromi Ando, Dennis E. Vance, René L. Jacobs, Jelske N. van der Veen
Hepatol Commun. 2019 Feb; 3(2): 262–276. Published online 2019 Jan 2. doi: 10.1002/hep4.1302
PMCID:
PMC6357837
AbstractArticlePDF–1.0M
9.
CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice
Jin Li, Su-Ping Deng, Gang Wei, Peng Yu
Database (Oxford) 2018; 2018: bay012. Published online 2018 Mar 23. doi: 10.1093/database/bay012
PMCID:
PMC5868181
AbstractArticlePDF–653K
10.
Fenofibrate, but not ezetimibe, prevents fatty liver disease in mice lacking phosphatidylethanolamine N-methyltransferase
Jelske N. van der Veen, Susanne Lingrell, Xia Gao, Abhijit Takawale, Zamaneh Kassiri, Dennis E. Vance, René L. Jacobs
J Lipid Res. 2017 Apr; 58(4): 656–667. Published online 2017 Mar 29. doi: 10.1194/jlr.M070631
PMCID:
PMC5392742
AbstractArticlePDF–1.5M
11.
Towards Functional Annotation of the Preimplantation Transcriptome: An RNAi Screen in Mammalian Embryos
Wei Cui, Xiangpeng Dai, Chelsea Marcho, Zhengbin Han, Kun Zhang, Kimberly D. Tremblay, Jesse Mager
Sci Rep. 2016; 6: 37396. Published online 2016 Nov 21. doi: 10.1038/srep37396
PMCID:
PMC5116644
AbstractArticlePDF–2.1M
12.
Ces3/TGH Deficiency Attenuates Steatohepatitis
Jihong Lian, Enhui Wei, Jody Groenendyk, Subhash K. Das, Martin Hermansson, Lena Li, Russell Watts, Aducio Thiesen, Gavin Y. Oudit, Marek Michalak, Richard Lehner
Sci Rep. 2016; 6: 25747. Published online 2016 May 16. doi: 10.1038/srep25747
PMCID:
PMC4867576
AbstractArticlePDF–2.6M
13.
Insufficiency of phosphatidylethanolamine N-methyltransferase is risk for lean non-alcoholic steatohepatitis
Atsuko Nakatsuka, Makoto Matsuyama, Satoshi Yamaguchi, Akihiro Katayama, Jun Eguchi, Kazutoshi Murakami, Sanae Teshigawara, Daisuke Ogawa, Nozomu Wada, Tetsuya Yasunaka, Fusao Ikeda, Akinobu Takaki, Eijiro Watanabe, Jun Wada
Sci Rep. 2016; 6: 21721. Published online 2016 Feb 17. doi: 10.1038/srep21721
PMCID:
PMC4756298
AbstractArticlePDF–3.1M
14.
Insufficient glucose supply is linked to hypothermia upon cold exposure in high-fat diet-fed mice lacking PEMT
Xia Gao, Jelske N. van der Veen, Carlos Fernandez-Patron, Jean E. Vance, Dennis E. Vance, René L. Jacobs
J Lipid Res. 2015 Sep; 56(9): 1701–1710. doi: 10.1194/jlr.M059287
PMCID:
PMC4548774
AbstractArticlePDF–1.1M
15.
Functional characterization of enzymes catalyzing ceramide phosphoethanolamine biosynthesis in mice
Andreas Bickert, Christina Ginkel, Matthijs Kol, Katharina vom Dorp, Holger Jastrow, Joachim Degen, René L. Jacobs, Dennis E. Vance, Elke Winterhager, Xian-Cheng Jiang, Peter Dörmann, Pentti Somerharju, Joost C. M. Holthuis, Klaus Willecke
J Lipid Res. 2015 Apr; 56(4): 821–835. doi: 10.1194/jlr.M055269
Correction in:
J Lipid Res. 2017 Apr; 58(4): 820.
PMCID:
PMC4373740
AbstractArticlePDF–2.7M
16.
Pemt Deficiency Ameliorates Endoplasmic Reticulum Stress in Diabetic Nephropathy
Mayu Watanabe, Atsuko Nakatsuka, Kazutoshi Murakami, Kentaro Inoue, Takahiro Terami, Chigusa Higuchi, Akihiro Katayama, Sanae Teshigawara, Jun Eguchi, Daisuke Ogawa, Eijiro Watanabe, Jun Wada, Hirofumi Makino
PLoS One. 2014; 9(3): e92647. Published online 2014 Mar 25. doi: 10.1371/journal.pone.0092647
PMCID:
PMC3965443
AbstractArticlePDF–5.6M
17.
Choline Supplementation Promotes Hepatic Insulin Resistance in Phosphatidylethanolamine N-Methyltransferase-deficient Mice via Increased Glucagon Action
Gengshu Wu, Liyan Zhang, Tete Li, Azeret Zuniga, Gary D. Lopaschuk, Liang Li, René L. Jacobs, Dennis E. Vance
J Biol Chem. 2013 Jan 11; 288(2): 837–847. Published online 2012 Nov 25. doi: 10.1074/jbc.M112.415117
PMCID:
PMC3543033
AbstractArticlePDF–1.6M
18.
The Membrane Lipid Phosphatidylcholine Is an Unexpected Source of Triacylglycerol in the Liver
Jelske N. van der Veen, Susanne Lingrell, Dennis E. Vance
J Biol Chem. 2012 Jul 6; 287(28): 23418–23426. Published online 2012 May 18. doi: 10.1074/jbc.M112.381723
PMCID:
PMC3390618
AbstractArticlePDF–1.0M
19.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
20.
Sequential Synthesis and Methylation of Phosphatidylethanolamine Promote Lipid Droplet Biosynthesis and Stability in Tissue Culture and in Vivo
Gerd Hörl, Andrea Wagner, Laura K. Cole, Roland Malli, Helga Reicher, Petra Kotzbeck, Harald Köfeler, Gerald Höfler, Sasa Frank, Juliane G. Bogner-Strauss, Wolfgang Sattler, Dennis E. Vance, Ernst Steyrer
J Biol Chem. 2011 May 13; 286(19): 17338–17350. Published online 2011 Mar 22. doi: 10.1074/jbc.M111.234534
PMCID:
PMC3089575
AbstractArticlePDF–2.0M

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