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Items: 1 to 20 of 47

1.
In vitro differentiation of mouse pluripotent stem cells into corticosteroid-producing adrenocortical cells
Ioannis Oikonomakos, Melina Tedesco, Fariba Jian Motamedi, Mirko Peitzsch, Serge Nef, Stefan R. Bornstein, Andreas Schedl, Charlotte Steenblock, Yasmine Neirijnck
Stem Cell Reports. 2024 Sep 10; 19(9): 1289–1303. Published online 2024 Aug 22. doi: 10.1016/j.stemcr.2024.07.010
PMCID:
PMC11411339
AbstractArticlePDF–5.7M
2.
Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
Arezoo Daryadel, Cong Tang, Ye Xie, Mirko Peitzsch, Viktoria Fisi, Constanze Hantel, Dominique Loffing-Cueni, David T Breault, David Penton, Johannes Loffing, Felix Beuschlein
Endocrinology. 2024 May; 165(5): bqae040. Published online 2024 Apr 4. doi: 10.1210/endocr/bqae040
PMCID:
PMC11002783
AbstractArticle
3.
Adrenal Abcg1 Controls Cholesterol Flux and Steroidogenesis
Jani Liimatta, Evelyn Curschellas, Emre Murat Altinkilic, Rawda Naamneh Elzenaty, Philipp Augsburger, Therina du Toit, Clarissa D Voegel, David T Breault, Christa E Flück, Emanuele Pignatti
Endocrinology. 2024 Mar; 165(3): bqae014. Published online 2024 Feb 1. doi: 10.1210/endocr/bqae014
PMCID:
PMC10863561
AbstractArticle
4.
Dietary anions control potassium excretion: it is more than a poorly absorbable anion effect
Lama Al-Qusairi, Mohammed Z. Ferdaus, Truyen D. Pham, Dimin Li, P. Richard Grimm, Ava M. Zapf, Delaney C. Abood, Ebrahim Tahaei, Eric Delpire, Susan M. Wall, Paul A. Welling
Am J Physiol Renal Physiol. 2023 Sep 1; 325(3): F377–F393. Published online 2023 Jul 27. doi: 10.1152/ajprenal.00193.2023
PMCID:
PMC10639028
AbstractArticle
5.
Calcineurin regulates aldosterone production via dephosphorylation of NFATC4
Mesut Berber, Sining Leng, Agnieszka Wengi, Denise V. Winter, Alex Odermatt, Felix Beuschlein, Johannes Loffing, David T. Breault, David Penton
JCI Insight. 2023 Jul 24; 8(14): e157027. Published online 2023 Jul 24. doi: 10.1172/jci.insight.157027
PMCID:
PMC10443813
AbstractArticlePDF–1.6M
6.
β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
Dipika R. Mohan, Kleiton S. Borges, Isabella Finco, Christopher R. LaPensee, Juilee Rege, April L. Solon, Donald W. Little, III, Tobias Else, Madson Q. Almeida, Derek Dang, James Haggerty-Skeans, April A. Apfelbaum, Michelle Vinco, Alda Wakamatsu, Beatriz M. P. Mariani, Larissa Costa Amorim, Ana Claudia Latronico, Berenice B. Mendonca, Maria Claudia N. Zerbini, Elizabeth R. Lawlor, Ryoma Ohi, Richard J. Auchus, William E. Rainey, Suely K. N. Marie, Thomas J. Giordano, Sriram Venneti, Maria Candida Barisson Villares Fragoso, David T. Breault, Antonio Marcondes Lerario, Gary D. Hammer
Cancer Res. Author manuscript; available in PMC 2024 Jan 5.
Published in final edited form as: Cancer Res. 2023 Jul 5; 83(13): 2123–2141. doi: 10.1158/0008-5472.CAN-22-2712
PMCID:
PMC10330305
AbstractArticlePDF–4.4M
7.
Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Nicole Bechmann, Sameh A. Youssef, Alain de Bruin, Elvira R. M. Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl
Dis Model Mech. 2023 Jun 1; 16(6): dmm050053. Published online 2023 May 10. doi: 10.1242/dmm.050053
PMCID:
PMC10184674
AbstractArticle
8.
Adrenal-Specific KO of the Circadian Clock Protein BMAL1 Alters Blood Pressure Rhythm and Timing of Eating Behavior
Hannah M Costello, G Ryan Crislip, Kit-Yan Cheng, I Jeanette Lynch, Alexandria Juffre, Phillip Bratanatawira, Annalisse Mckee, Ryanne S Thelwell, Victor M Mendez, Charles S Wingo, Lauren G Douma, Michelle L Gumz
Function (Oxf) 2023; 4(2): zqad001. Published online 2023 Jan 9. doi: 10.1093/function/zqad001
PMCID:
PMC9909366
AbstractArticlePDF–6.4M
9.
Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
Mitchell H. Omar, Dominic P. Byrne, Kiana N. Jones, Tyler M. Lakey, Kerrie B. Collins, Kyung-Soon Lee, Leonard A. Daly, Katherine A. Forbush, Ho-Tak Lau, Martin Golkowski, G. Stanley McKnight, David T. Breault, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Claire E. Eyers, Geoffrey S. Baird, Shao-En Ong, F. Donelson Smith, Patrick A. Eyers, John D. Scott
Cell Rep. Author manuscript; available in PMC 2022 Jul 25.
Published in final edited form as: Cell Rep. 2022 Jul 12; 40(2): 111073. doi: 10.1016/j.celrep.2022.111073
PMCID:
PMC9311266
AbstractArticlePDF–3.4M
10.
Embryonic osteocalcin signaling determines lifelong adrenal steroidogenesis and homeostasis in the mouse
Vijay K. Yadav, Julian M. Berger, Parminder Singh, Perumal Nagarajan, Gerard Karsenty
J Clin Invest. 2022 Feb 15; 132(4): e153752. Published online 2022 Feb 15. doi: 10.1172/JCI153752
PMCID:
PMC8843753
AbstractArticlePDF–4.9M
11.
Effects of intron conversion in the human CYP11B2 gene on its transcription and blood pressure regulation in transgenic mice
Brahmaraju Mopidevi, Indu Sivankutty, Shoujin Hao, Nicholas R. Ferreri, Ashok Kumar
J Biol Chem. 2020 Aug 7; 295(32): 11068–11081. Published online 2020 Jun 15. doi: 10.1074/jbc.RA120.013047
PMCID:
PMC7415971
AbstractArticlePDF–3.5M
12.
Wnt/β-catenin activation cooperates with loss of p53 to cause adrenocortical carcinoma in mice
Kleiton Silva Borges, Emanuele Pignatti, Sining Leng, Dulanjalee Kariyawasam, Gerard Ruiz-Babot, Fernando Silva Ramalho, Makoto Mark Taketo, Diana L. Carlone, David T. Breault
Oncogene. 2020; 39(30): 5282–5291. Published online 2020 Jun 19. doi: 10.1038/s41388-020-1358-5
PMCID:
PMC7378041
AbstractArticlePDF–2.6M
13.
Beta-Catenin Causes Adrenal Hyperplasia by Blocking Zonal Transdifferentiation
Emanuele Pignatti, Sining Leng, Yixing Yuchi, Kleiton S. Borges, Nick A. Guagliardo, Manasvi S. Shah, Gerard Ruiz-Babot, Dulanjalee Kariyawasam, Makoto Mark Taketo, Ji Miao, Paula Q. Barrett, Diana L. Carlone, David T. Breault
Cell Rep. Author manuscript; available in PMC 2020 Jun 9.
Published in final edited form as: Cell Rep. 2020 Apr 21; 31(3): 107524. doi: 10.1016/j.celrep.2020.107524
PMCID:
PMC7281829
AbstractArticlePDF–3.3M
14.
β-Catenin and FGFR2 regulate postnatal rosette-based adrenocortical morphogenesis
Sining Leng, Emanuele Pignatti, Radhika S. Khetani, Manasvi S. Shah, Simiao Xu, Ji Miao, Makoto M. Taketo, Felix Beuschlein, Paula Q. Barrett, Diana L. Carlone, David T. Breault
Nat Commun. 2020; 11: 1680. Published online 2020 Apr 3. doi: 10.1038/s41467-020-15332-7
PMCID:
PMC7125176
AbstractArticlePDF–43M
15.
Angiotensin II induces coordinated calcium bursts in aldosterone-producing adrenal rosettes
Nick A. Guagliardo, Peter M. Klein, Christina A. Gancayco, Adam Lu, Sining Leng, Rany R. Makarem, Chelsea Cho, Craig G. Rusin, David T. Breault, Paula Q. Barrett, Mark P. Beenhakker
Nat Commun. 2020; 11: 1679. Published online 2020 Apr 3. doi: 10.1038/s41467-020-15408-4
PMCID:
PMC7125102
AbstractArticlePDF–4.0M
16.
Sex Differences in Adrenal Bmal1 Deletion–Induced Augmentation of Glucocorticoid Responses to Stress and ACTH in Mice
William C Engeland, Logan Massman, Lauren Miller, Sining Leng, Emanuele Pignatti, Lorena Pantano, Diana L Carlone, Paulo Kofuji, David T Breault
Endocrinology. 2019 Oct; 160(10): 2215–2229. Published online 2019 Jul 29. doi: 10.1210/en.2019-00357
PMCID:
PMC6735739
AbstractArticle
17.
A ZNRF3-dependent Wnt/β-catenin signaling gradient is required for adrenal homeostasis
Kaitlin J. Basham, Stéphanie Rodriguez, Adina F. Turcu, Antonio M. Lerario, Catriona Y. Logan, Madeline R. Rysztak, Celso E. Gomez-Sanchez, David T. Breault, Bon-Kyoung Koo, Hans Clevers, Roeland Nusse, Pierre Val, Gary D. Hammer
Genes Dev. 2019 Feb 1; 33(3-4): 209–220. doi: 10.1101/gad.317412.118
PMCID:
PMC6362817
AbstractArticlePDF–10M
18.
Adrenal tissue-specific deletion of TASK channels causes aldosterone-driven Angiotensin II-independent hypertension.
Nick A. Guagliardo, Junlan Yao, Eric J. Stipes, Sylvia Cechova, Thu H. Le, Douglas A. Bayliss, David T. Breault, Paula Q. Barrett
Hypertension. Author manuscript; available in PMC 2020 Feb 1.
Published in final edited form as: Hypertension. 2019 Feb; 73(2): 407–414. doi: 10.1161/HYPERTENSIONAHA.118.11962
PMCID:
PMC6326871
AbstractArticlePDF–711K
19.
Steroidogenic differentiation and PKA signaling are programmed by histone methyltransferase EZH2 in the adrenal cortex
Mickael Mathieu, Coralie Drelon, Stéphanie Rodriguez, Houda Tabbal, Amandine Septier, Christelle Damon-Soubeyrand, Typhanie Dumontet, Annabel Berthon, Isabelle Sahut-Barnola, Cyril Djari, Marie Batisse-Lignier, Jean-Christophe Pointud, Damien Richard, Gwenneg Kerdivel, Marie-Ange Calméjane, Valentina Boeva, Igor Tauveron, Anne-Marie Lefrançois-Martinez, Antoine Martinez, Pierre Val
Proc Natl Acad Sci U S A. 2018 Dec 26; 115(52): E12265–E12274. Published online 2018 Dec 12. doi: 10.1073/pnas.1809185115
PMCID:
PMC6310834
AbstractArticlePDF–2.4M
20.
The Adrenal Clock Prevents Aberrant Light-Induced Alterations in Circadian Glucocorticoid Rhythms
William C Engeland, Logan Massman, Shubhendu Mishra, J Marina Yoder, Sining Leng, Emanuele Pignatti, Mary E Piper, Diana L Carlone, David T Breault, Paulo Kofuji
Endocrinology. 2018 Dec; 159(12): 3950–3964. Published online 2018 Oct 12. doi: 10.1210/en.2018-00769
PMCID:
PMC6240903
AbstractArticle

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