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Select item 111390711.

δ-Protocadherins: a gene family expressed differentially in the mouse brain

K. Vanhalst, P. Kools, K. Staes, F. van Roy, C. Redies

Cell Mol Life Sci. 2005 Jun; 62(11): 1247–1259. Published online 2005 May 18. doi: 10.1007/s00018-005-5021-7

PMCID:: PMC11139071

Abstract Article PDF–3.3M

Select item 109176602.

Genetic determinants of micronucleus formation in vivo

D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus

Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0

PMCID:: PMC10917660

Abstract Article PDF–4.8M

Select item 99269713.

Protein phosphatase PPM1A inhibition attenuates osteoarthritis via regulating TGF-β/Smad2 signaling in chondrocytes

Qinwen Ge, Zhenyu Shi, Kai-ao Zou, Jun Ying, Jiali Chen, Wenhua Yuan, Weidong Wang, Luwei Xiao, Xia Lin, Di Chen, Xin-Hua Feng, Ping-er Wang, Peijian Tong, Hongting Jin

JCI Insight. 2023 Feb 8; 8(3): e166688. Published online 2023 Feb 8. doi: 10.1172/jci.insight.166688

PMCID:: PMC9926971

Abstract Article PDF–3.8M

Select item 79783834.

The protein phosphatase PPM1A dephosphorylates and activates YAP to govern mammalian intestinal and liver regeneration

Ruyuan Zhou, Qirou Wu, Mengqiu Wang, Seema Irani, Xiao Li, Qian Zhang, Fansen Meng, Shengduo Liu, Fei Zhang, Liming Wu, Xia Lin, Xiaojian Wang, Jian Zou, Hai Song, Jun Qin, Tingbo Liang, Xin-Hua Feng, Yan Jessie Zhang, Pinglong Xu

PLoS Biol. 2021 Feb; 19(2): e3001122. Published online 2021 Feb 25. doi: 10.1371/journal.pbio.3001122

PMCID:: PMC7978383

Abstract Article PDF–5.0M

Select item 79387705.

BraInMap elucidates the macromolecular connectivity landscape of mammalian brain

Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili

Cell Syst. Author manuscript; available in PMC 2021 Apr 22.

Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003

Correction in:: Cell Syst. 2020 Aug 26; 11(2): 208.

PMCID:: PMC7938770

Abstract Article PDF–2.0M

Select item 72186916.

Protein phosphatase magnesium-dependent 1A induces inflammation in rheumatoid arthritis

Beomgu Lee, You Seon Song, Christopher Rhodes, Tae Sik Goh, Jong Seong Roh, Hoim Jeong, Jisu Park, Han-Na Lee, Seung-Geun Lee, Soohyun Kim, Mingyo Kim, Sang-Il Lee, Dong Hyun Sohn, William H. Robinson

Biochem Biophys Res Commun. Author manuscript; available in PMC 2021 Feb 12.

Published in final edited form as: Biochem Biophys Res Commun. 2020 Feb 12; 522(3): 731–735. Published online 2019 Nov 30. doi: 10.1016/j.bbrc.2019.11.112

PMCID:: PMC7218691

Abstract Article PDF–1005K

Select item 70722547.

PPM1A Controls Diabetic Gene Programming through Directly Dephosphorylating PPARγ at Ser273

Keon Woo Khim, Sun Sil Choi, Hyun-Jun Jang, Yo Han Lee, Eujin Lee, Ji-Min Hyun, Hye-Jin Eom, Sora Yoon, Jeong-Won Choi, Tae-Eun Park, Dougu Nam, Jang Hyun Choi

Cells. 2020 Feb; 9(2): 343. Published online 2020 Feb 2. doi: 10.3390/cells9020343

PMCID:: PMC7072254

Abstract Article PDF–3.0M

Select item 62757998.

De novo synthesis of protein phosphatase 1A, magnesium dependent, alpha isoform (PPM1A) during oocyte maturation

Dana Chuderland, Zeev Dvashi, Ruth Kaplan-Kraicer, Daniella Ben-Meir, Ruth Shalgi, Sara Lavi

Cell Mol Biol Lett. 2012 Sep; 17(3): 433–445. Published online 2012 Jun 5. doi: 10.2478/s11658-012-0022-7

PMCID:: PMC6275799

Summary PDF–350K

Select item 53812269.

Fancd2 in vivo interaction network reveals a non-canonical role in mitochondrial function

Tingting Zhang, Wei Du, Andrew F. Wilson, Satoshi H. Namekawa, Paul R. Andreassen, Amom Ruhikanta Meetei, Qishen Pang

Sci Rep. 2017; 7: 45626. Published online 2017 Apr 5. doi: 10.1038/srep45626

PMCID:: PMC5381226

Abstract Article PDF–1.4M

Select item 534152010.

The antiobesity factor WDTC1 suppresses adipogenesis via the CRL4^WDTC¹ E3 ligase

Beezly S Groh, Feng Yan, Matthew D Smith, Yanbao Yu, Xian Chen, Yue Xiong

EMBO Rep. 2016 May; 17(5): 638–647. Published online 2016 Apr 9. doi: 10.15252/embr.201540500

PMCID:: PMC5341520

Abstract Article PDF–1.1M

Select item 529582111.

High-throughput discovery of novel developmental phenotypes

Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray

Nature. Author manuscript; available in PMC 2017 Mar 14.

Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356

Correction in:: Nature. 2017 Nov 16; 551(7680): 398.

PMCID:: PMC5295821

Abstract Article PDF–3.0M

Select item 494233812.

PPM1A silences cytosolic RNA sensing and antiviral defense through direct dephosphorylation of MAVS and TBK1

Weiwen Xiang, Qian Zhang, Xia Lin, Shiying Wu, Yao Zhou, Fansen Meng, Yunyun Fan, Tao Shen, Mu Xiao, Zongping Xia, Jian Zou, Xin-Hua Feng, Pinglong Xu

Sci Adv. 2016 Jul; 2(7): e1501889. Published online 2016 Jul 1. doi: 10.1126/sciadv.1501889

PMCID:: PMC4942338

Abstract Article PDF–1.2M

Select item 437677713.

PPM1A Regulates Antiviral Signaling by Antagonizing TBK1-Mediated STING Phosphorylation and Aggregation

Zexing Li, Ge Liu, Liwei Sun, Yan Teng, Xuejiang Guo, Jianhang Jia, Jiahao Sha, Xiao Yang, Dahua Chen, Qinmiao Sun

PLoS Pathog. 2015 Mar; 11(3): e1004783. Published online 2015 Mar 27. doi: 10.1371/journal.ppat.1004783

PMCID:: PMC4376777

Abstract Article PDF–5.7M

Select item 417620014.

C-terminal Domain (CTD) Small Phosphatase-like 2 Modulates the Canonical Bone Morphogenetic Protein (BMP) Signaling and Mesenchymal Differentiation via Smad Dephosphorylation

Yulan Zhao, Mu Xiao, Baoguo Sun, Zhengmao Zhang, Tao Shen, Xueyan Duan, Paul Borchyung Yu, Xin-Hua Feng, Xia Lin

J Biol Chem. 2014 Sep 19; 289(38): 26441–26450. Published online 2014 Aug 6. doi: 10.1074/jbc.M114.568964

PMCID:: PMC4176200

Abstract Article PDF–2.1M

Select item 396495515.

The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data

Gautier Koscielny, Gagarine Yaikhom, Vivek Iyer, Terrence F. Meehan, Hugh Morgan, Julian Atienza-Herrero, Andrew Blake, Chao-Kung Chen, Richard Easty, Armida Di Fenza, Tanja Fiegel, Mark Grifiths, Alan Horne, Natasha A. Karp, Natalja Kurbatova, Jeremy C. Mason, Peter Matthews, Darren J. Oakley, Asfand Qazi, Jack Regnart, Ahmad Retha, Luis A. Santos, Duncan J. Sneddon, Jonathan Warren, Henrik Westerberg, Robert J. Wilson, David G. Melvin, Damian Smedley, Steve D. M. Brown, Paul Flicek, William C. Skarnes, Ann-Marie Mallon, Helen Parkinson

Nucleic Acids Res. 2014 Jan 1; 42(Database issue): D802–D809. Published online 2013 Nov 3. doi: 10.1093/nar/gkt977

PMCID:: PMC3964955

Abstract Article PDF–5.7M

Select item 384363716.

Inhibition of TGF-β Signaling at the Nuclear Envelope: Characterization of Interactions between MAN1, Smad2 and 3, and PPM1A

Benjamin Bourgeois, Bernard Gilquin, Carine Tellier-Lebègue, Cecilia Östlund, Wei Wu, Javier Pérez, Perla El Hage, François Lallemand, Howard J. Worman, Sophie Zinn-Justin

Sci Signal. Author manuscript; available in PMC 2013 Dec 18.

Published in final edited form as: Sci Signal. 2013 Jun 18; 6(280): 10.1126/scisignal.2003411. Published online 2013 Jun 18. doi: 10.1126/scisignal.2003411