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Items: 1 to 20 of 42

1.
Genetic determinants of micronucleus formation in vivo
D. J. Adams, B. Barlas, R. E. McIntyre, I. Salguero, L. van der Weyden, A. Barros, J. R. Vicente, N. Karimpour, A. Haider, M. Ranzani, G. Turner, N. A. Thompson, V. Harle, R. Olvera-León, C. D. Robles-Espinoza, A. O. Speak, N. Geisler, W. J. Weninger, S. H. Geyer, J. Hewinson, N. A. Karp, The Sanger Mouse Genetics Project, B. Fu, F. Yang, Z. Kozik, J. Choudhary, L. Yu, M. S. van Ruiten, B. D. Rowland, C. J. Lelliott, M. del Castillo Velasco-Herrera, R. Verstraten, L. Bruckner, A. G. Henssen, M. A. Rooimans, J. de Lange, T. J. Mohun, M. J. Arends, K. A. Kentistou, P. A. Coelho, Y. Zhao, H. Zecchini, J. R. B. Perry, S. P. Jackson, G. Balmus
Nature. 2024; 627(8002): 130–136. Published online 2024 Feb 14. doi: 10.1038/s41586-023-07009-0
PMCID:
PMC10917660
AbstractArticlePDF–4.8M
2.
Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome
Brianna K. Unda, Leon Chalil, Sehyoun Yoon, Savannah Kilpatrick, Courtney Irwin, Sansi Xing, Nadeem Murtaza, Anran Cheng, Chad Brown, Alexandria Afonso, Elizabeth McCready, Gabriel M. Ronen, Jennifer Howe, Aurélie Caye-Eude, Alain Verloes, Brad W. Doble, Laurence Faivre, Antonio Vitobello, Stephen W. Scherer, Yu Lu, Peter Penzes, Karun K. Singh
Mol Psychiatry. 2023; 28(4): 1747–1769. Published online 2023 Jan 6. doi: 10.1038/s41380-022-01937-5
PMCID:
PMC10208958
AbstractArticlePDF–7.0M
3.
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development
Francesco Bedogni, Robert F. Hevner
Front Mol Neurosci. 2021; 14: 686034. Published online 2021 Jul 12. doi: 10.3389/fnmol.2021.686034
PMCID:
PMC8313239
AbstractArticlePDF–1.6M
4.
Proteotyping of knockout mouse strains reveals sex- and strain-specific signatures in blood plasma
Yassene Mohammed, Sarah A. Michaud, Helena Pětrošová, Juncong Yang, Milan Ganguly, David Schibli, Ann M. Flenniken, Lauryl M. J. Nutter, Hibret A. Adissu, K. C. Kent Lloyd, Colin McKerlie, Christoph H. Borchers
NPJ Syst Biol Appl. 2021; 7: 25. Published online 2021 May 28. doi: 10.1038/s41540-021-00184-8
PMCID:
PMC8163790
AbstractArticlePDF–6.9M
5.
BraInMap elucidates the macromolecular connectivity landscape of mammalian brain
Reza Pourhaghighi, Peter E. A. Ash, Sadhna Phanse, Florian Goebels, Lucas Z. M. Hu, Siwei Chen, Yingying Zhang, Shayne D. Wierbowski, Samantha Boudeau, Mohamed T. Moutaoufik, Ramy H. Malty, Edyta Malolepsza, Kalliopi Tsafou, Aparna Nathan, Graham Cromar, Hongbo Guo, Ali Al Abdullatif, Daniel J. Apicco, Lindsay A. Becker, Aaron D. Gitler, Stefan M. Pulst, Ahmed Youssef, Ryan Hekman, Pierre C. Havugimana, Carl A. White, Benjamin C. Blum, Antonia Ratti, Camron D. Bryant, John Parkinson, Kasper Lage, Mohan Babu, Haiyuan Yu, Gary D. Bader, Benjamin Wolozin, Andrew Emili
Cell Syst. Author manuscript; available in PMC 2021 Apr 22.
Published in final edited form as: Cell Syst. 2020 Apr 22; 10(4): 333–350.e14. doi: 10.1016/j.cels.2020.03.003
Correction in:
Cell Syst. 2020 Aug 26; 11(2): 208.
PMCID:
PMC7938770
AbstractArticlePDF–2.0M
6.
Unbalanced growth in mouse cells with amplified dhfr genes
R. M. Snapka, S. Ge, J. Trask, F. Robertson
Cell Prolif. 1997 Oct; 30(10): 385–399. Published online 2003 Oct 29. doi: 10.1046/j.1365-2184.1997.00102.x
PMCID:
PMC6496445
SummaryPDF–2.6M
7.
Knockout of dihydrofolate reductase in mice induces hypertension and abdominal aortic aneurysm via mitochondrial dysfunction
Qiang Li, Ji Youn Youn, Kin Lung Siu, Priya Murugesan, Yixuan Zhang, Hua Cai
Redox Biol. 2019 Jun; 24: 101185. Published online 2019 Mar 29. doi: 10.1016/j.redox.2019.101185
PMCID:
PMC6451172
AbstractArticlePDF–2.9M
8.
Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity
Qinjie Weng, Jiajia Wang, Jiaying Wang, Biqin Tan, Jing Wang, Haibo Wang, Tao Zheng, Q. Richard Lu, Bo Yang, Qiaojun He
Sci Rep. 2017; 7: 1705. Published online 2017 May 11. doi: 10.1038/s41598-017-01732-1
PMCID:
PMC5431811
AbstractArticlePDF–4.7M
9.
High-throughput discovery of novel developmental phenotypes
Mary E. Dickinson, Ann M. Flenniken, Xiao Ji, Lydia Teboul, Michael D. Wong, Jacqueline K. White, Terrence F. Meehan, Wolfgang J. Weninger, Henrik Westerberg, Hibret Adissu, Candice N. Baker, Lynette Bower, James M. Brown, L. Brianna Caddle, Francesco Chiani, Dave Clary, James Cleak, Mark J. Daly, James M. Denegre, Brendan Doe, Mary E. Dolan, Sarah M. Edie, Helmut Fuchs, Valerie Gailus-Durner, Antonella Galli, Alessia Gambadoro, Juan Gallegos, Shiying Guo, Neil R. Horner, Chih-wei Hsu, Sara J. Johnson, Sowmya Kalaga, Lance C. Keith, Louise Lanoue, Thomas N. Lawson, Monkol Lek, Manuel Mark, Susan Marschall, Jeremy Mason, Melissa L. McElwee, Susan Newbigging, Lauryl M.J. Nutter, Kevin A. Peterson, Ramiro Ramirez-Solis, Douglas J. Rowland, Edward Ryder, Kaitlin E. Samocha, John R. Seavitt, Mohammed Selloum, Zsombor Szoke-Kovacs, Masaru Tamura, Amanda G Trainor, Ilinca Tudose, Shigeharu Wakana, Jonathan Warren, Olivia Wendling, David B. West, Leeyean Wong, Atsushi Yoshiki, The International Mouse Phenotyping Consortium, Daniel G. MacArthur, Glauco P. Tocchini-Valentini, Xiang Gao, Paul Flicek, Allan Bradley, William C. Skarnes, Monica J. Justice, Helen E. Parkinson, Mark Moore, Sara Wells, Robert E. Braun, Karen L. Svenson, Martin Hrabe de Angelis, Yann Herault, Tim Mohun, Ann-Marie Mallon, R. Mark Henkelman, Steve D.M. Brown, David J. Adams, K.C. Kent Lloyd, Colin McKerlie, Arthur L. Beaudet, Maja Bucan, Stephen A. Murray
Nature. Author manuscript; available in PMC 2017 Mar 14.
Published in final edited form as: Nature. 2016 Sep 22; 537(7621): 508–514. Published online 2016 Sep 14. doi: 10.1038/nature19356
Correction in:
Nature. 2017 Nov 16; 551(7680): 398.
PMCID:
PMC5295821
AbstractArticlePDF–3.0M
10.
Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr
Julie A. I. Thoms, Kathy Knezevic, Jia Jenny Liu, Elias N. Glaros, Thuan Thai, Qiao Qiao, Heather Campbell, Deborah Packham, Yizhou Huang, Peter Papathanasiou, Robert Tunningley, Belinda Whittle, Amanda W. S. Yeung, Vashe Chandrakanthan, Luke Hesson, Vivien Chen, Jason W. H. Wong, Louise E. Purton, Robyn L. Ward, Shane R. Thomas, John E. Pimanda
Mol Cell Biol. 2016 Apr 15; 36(8): 1222–1236. Prepublished online 2016 Feb 1. Published online 2016 Apr 1. doi: 10.1128/MCB.01035-15
PMCID:
PMC4836279
AbstractArticlePDF–4.1M
11.
Regulation of Hematopoiesis and Methionine Homeostasis by mTORC1 Inhibitor NPRL2
Paul A. Dutchak, Sunil Laxman, Sandi Jo Estill, Chensu Wang, Yun Wang, Yiguang Wang, Gamze B. Bulut, Jinming Gao, Lily J. Huang, Benjamin P. Tu
Cell Rep. Author manuscript; available in PMC 2016 Jul 21.
Published in final edited form as: Cell Rep. 2015 Jul 21; 12(3): 371–379. Published online 2015 Jul 9. doi: 10.1016/j.celrep.2015.06.042
PMCID:
PMC4830278
AbstractArticlePDF–1.4M
12.
Endothelial Nitric Oxide Synthase Derived Nitric Oxide Prevents Dihydrofolate Reductase Degradation via Promoting S-nitrosylation
Zhejun Cai, Qiulun Lu, Ye Ding, Qilong Wang, Lei Xiao, Ping Song, Ming-Hui Zou
Arterioscler Thromb Vasc Biol. Author manuscript; available in PMC 2016 Nov 1.
Published in final edited form as: Arterioscler Thromb Vasc Biol. 2015 Nov; 35(11): 2366–2373. Published online 2015 Sep 17. doi: 10.1161/ATVBAHA.115.305796
PMCID:
PMC4758687
AbstractArticlePDF–1.7M
13.
The goya mouse mutant reveals distinct newly identified roles for MAP3K1 in the development and survival of cochlear sensory hair cells
Andrew Parker, Sally H. Cross, Ian J. Jackson, Rachel Hardisty-Hughes, Susan Morse, George Nicholson, Emma Coghill, Michael R. Bowl, Steve D. M. Brown
Dis Model Mech. 2015 Dec 1; 8(12): 1555–1568. doi: 10.1242/dmm.023176
PMCID:
PMC4728324
AbstractArticle
14.
Proliferation in the Absence of E2F1-3
Pamela L. Wenzel, Jean-Leon Chong, M. Teresa Sáenz-Robles, Antoney Ferrey, John P. Hagan, Yorman M. Gomez, Ravi Rajmohan, Nidhi Sharma, Hui-Zi Chen, James M. Pipas, Michael L. Robinson, Gustavo Leone
Dev Biol. Author manuscript; available in PMC 2013 Dec 19.
Published in final edited form as: Dev Biol. 2011 Mar 1; 351(1): 10.1016/j.ydbio.2010.12.025. Published online 2010 Dec 23. doi: 10.1016/j.ydbio.2010.12.025
PMCID:
PMC3868453
AbstractArticlePDF–3.3M
15.
A conditional knockout resource for the genome–wide study of mouse gene function
William C. Skarnes, Barry Rosen, Anthony P. West, Manousos Koutsourakis, Wendy Bushell, Vivek Iyer, Alejandro O. Mujica, Mark Thomas, Jennifer Harrow, Tony Cox, David Jackson, Jessica Severin, Patrick Biggs, Jun Fu, Michael Nefedov, Pieter J. de Jong, A. Francis Stewart, Allan Bradley
Nature. Author manuscript; available in PMC 2013 Feb 14.
Published in final edited form as: Nature. 2011 Jun 15; 474(7351): 337–342. Published online 2011 Jun 15. doi: 10.1038/nature10163
PMCID:
PMC3572410
AbstractArticlePDF–1.1M
16.
Role of the AAA protease Yme1 in folding of proteins in the intermembrane space of mitochondria
Bernadette Schreiner, Heike Westerburg, Ignasi Forné, Axel Imhof, Walter Neupert, Dejana Mokranjac
Mol Biol Cell. 2012 Nov 15; 23(22): 4335–4346. doi: 10.1091/mbc.E12-05-0420
PMCID:
PMC3496608
AbstractArticlePDF–1.0M
17.
Protein unfolding and degradation by the AAA+ Lon protease
Eyal Gur, Marina Vishkautzan, Robert T Sauer
Protein Sci. 2012 Feb; 21(2): 268–278. Published online 2011 Dec 7. doi: 10.1002/pro.2013
PMCID:
PMC3324771
AbstractArticlePDF–939K
18.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
19.
Dihydrofolate reductase protects endothelial nitric oxide synthase from uncoupling in tetrahydrobiopterin deficiency
Mark J. Crabtree, Ashley B. Hale, Keith M. Channon
Free Radic Biol Med. 2011 Jun 1; 50(11): 1639–1646. doi: 10.1016/j.freeradbiomed.2011.03.010
PMCID:
PMC3121954
AbstractArticle
20.
A High-Resolution Anatomical Atlas of the Transcriptome in the Mouse Embryo
Graciana Diez-Roux, Sandro Banfi, Marc Sultan, Lars Geffers, Santosh Anand, David Rozado, Alon Magen, Elena Canidio, Massimiliano Pagani, Ivana Peluso, Nathalie Lin-Marq, Muriel Koch, Marchesa Bilio, Immacolata Cantiello, Roberta Verde, Cristian De Masi, Salvatore A. Bianchi, Juliette Cicchini, Elodie Perroud, Shprese Mehmeti, Emilie Dagand, Sabine Schrinner, Asja Nürnberger, Katja Schmidt, Katja Metz, Christina Zwingmann, Norbert Brieske, Cindy Springer, Ana Martinez Hernandez, Sarah Herzog, Frauke Grabbe, Cornelia Sieverding, Barbara Fischer, Kathrin Schrader, Maren Brockmeyer, Sarah Dettmer, Christin Helbig, Violaine Alunni, Marie-Annick Battaini, Carole Mura, Charlotte N. Henrichsen, Raquel Garcia-Lopez, Diego Echevarria, Eduardo Puelles, Elena Garcia-Calero, Stefan Kruse, Markus Uhr, Christine Kauck, Guangjie Feng, Nestor Milyaev, Chuang Kee Ong, Lalit Kumar, MeiSze Lam, Colin A. Semple, Attila Gyenesei, Stefan Mundlos, Uwe Radelof, Hans Lehrach, Paolo Sarmientos, Alexandre Reymond, Duncan R. Davidson, Pascal Dollé, Stylianos E. Antonarakis, Marie-Laure Yaspo, Salvador Martinez, Richard A. Baldock, Gregor Eichele, Andrea Ballabio
PLoS Biol. 2011 Jan; 9(1): e1000582. Published online 2011 Jan 18. doi: 10.1371/journal.pbio.1000582
PMCID:
PMC3022534
AbstractArticlePDF–3.8M

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