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Items: 1 to 20 of 45

1.
Exploiting spatiotemporal regulation of FZD5 during neural patterning for efficient ventral midbrain specification
Andy Yang, Rony Chidiac, Emma Russo, Hendrik Steenland, Quinn Pauli, Robert Bonin, Levi L. Blazer, Jarrett J. Adams, Sachdev S. Sidhu, Aleksandrina Goeva, Ali Salahpour, Stephane Angers
Development. 2024 Mar 1; 151(5): dev202545. Published online 2024 Mar 4. doi: 10.1242/dev.202545
PMCID:
PMC10946437
AbstractArticle
2.
A desert lncRNA HIDEN regulates human endoderm differentiation via interacting with IMP1 and stabilizing FZD5 mRNA
Pei Lu, Jie Yang, Mao Li, Shanshan Wen, Tianzhe Zhang, Chenchao Yan, Ran Liu, Yu Xiao, Xinghuan Wang, Wei Jiang
Genome Biol. 2023; 24: 92. Published online 2023 Apr 24. doi: 10.1186/s13059-023-02925-w
PMCID:
PMC10124006
AbstractArticlePDF–5.9M
3.
Single-Cell Characterization of the Frizzled 5 (Fz5) Mutant Mouse and Human Persistent Fetal Vasculature (PFV)
Yuanyuan Chen, Cheng Wu, Shanzhen Peng, Dianlei Guo, Hong Ouyang, Yanhong Wei, Rong Ju, Xiaoyan Ding, Zhi Xie, Chunqiao Liu
Invest Ophthalmol Vis Sci. 2023 Mar; 64(3): 8. Published online 2023 Mar 3. doi: 10.1167/iovs.64.3.8
PMCID:
PMC9988703
AbstractArticlePDF–13M
4.
Aberrant Cholesterol Metabolism and Wnt/β‐Catenin Signaling Coalesce via Frizzled5 in Supporting Cancer Growth
Shaoqin Zheng, Jiahui Lin, Zhongqiu Pang, Hui Zhang, Yinuo Wang, Lanjing Ma, Haijiao Zhang, Xi Zhang, Maorong Chen, Xinjun Zhang, Chao Zhao, Jun Qi, Liu Cao, Min Wang, Xi He, Ren Sheng
Adv Sci (Weinh) 2022 Oct; 9(28): 2200750. Published online 2022 Aug 17. doi: 10.1002/advs.202200750
PMCID:
PMC9534957
AbstractArticlePDF–6.1M
5.
RNF43 R117fs mutant positively regulates Wnt/β-catenin signaling by failing to internalize FZD expressed on the cell surface
A-Ri Cho, Hee Jung Sul, Yoo Jin Kim, Bohyun Kim, Dae Young Zang
Sci Rep. 2022; 12: 7013. Published online 2022 Apr 29. doi: 10.1038/s41598-022-10868-8
PMCID:
PMC9054848
AbstractArticlePDF–1.6M
6.
Cardiac Wnt5a and Wnt11 promote fibrosis by the crosstalk of FZD5 and EGFR signaling under pressure overload
Yan Zou, Le Pan, Yi Shen, Xiang Wang, Chenxing Huang, Hao Wang, Xuejuan Jin, Chao Yin, Ying Wang, Jianguo Jia, Juying Qian, Yunzeng Zou, Hui Gong, Junbo Ge
Cell Death Dis. 2021 Oct; 12(10): 877. Published online 2021 Sep 25. doi: 10.1038/s41419-021-04152-2
PMCID:
PMC8464604
AbstractArticlePDF–9.6M
7.
Dual Proteome-scale Networks Reveal Cell-specific Remodeling of the Human Interactome
Edward L. Huttlin, Raphael J. Bruckner, Jose Navarrete-Perea, Joe R. Cannon, Kurt Baltier, Fana Gebreab, Melanie P. Gygi, Alexandra Thornock, Gabriela Zarraga, Stanley Tam, John Szpyt, Brandon M. Gassaway, Alexandra Panov, Hannah Parzen, Sipei Fu, Arvene Golbazi, Eila Maenpaa, Keegan Stricker, Sanjukta Guha Thakurta, Tian Zhang, Ramin Rad, Joshua Pan, David P. Nusinow, Joao A. Paulo, Devin K. Schweppe, Laura Pontano Vaites, J. Wade Harper, Steven P. Gygi
Cell. Author manuscript; available in PMC 2022 May 27.
Published in final edited form as: Cell. 2021 May 27; 184(11): 3022–3040.e28. Published online 2021 May 6. doi: 10.1016/j.cell.2021.04.011
PMCID:
PMC8165030
AbstractArticlePDF–2.2M
8.
FZD5 regulates cellular senescence in human mesenchymal stem/stromal cells
Seiko Harada, Yo Mabuchi, Jun Kohyama, Daisuke Shimojo, Sadafumi Suzuki, Yoshimi Kawamura, Daisuke Araki, Takashi Suyama, Masunori Kajikawa, Chihiro Akazawa, Hideyuki Okano, Yumi Matsuzaki
Stem Cells. 2021 Mar; 39(3): 318–330. Published online 2020 Dec 22. doi: 10.1002/stem.3317
PMCID:
PMC7986096
AbstractArticlePDF–11M
9.
FZD5 prevents epithelial-mesenchymal transition in gastric cancer
Dan Dong, Lei Na, Kailing Zhou, Zhuo Wang, Yu Sun, Qianqian Zheng, Jian Gao, Chenghai Zhao, Wei Wang
Cell Commun Signal. 2021; 19: 21. Published online 2021 Feb 22. doi: 10.1186/s12964-021-00708-z
PMCID:
PMC7898745
AbstractArticlePDF–7.2M
10.
Confirming and expanding the phenotypes of FZD5 variants: Coloboma, inferior chorioretinal hypoplasia, and high myopia
Yi Jiang, Jiamin Ouyang, Shiqiang Li, Xueshan Xiao, Wenmin Sun, Qingjiong Zhang
Mol Vis. 2021; 27: 50–60. Published online 2021 Jan 20.
PMCID:
PMC7883931
AbstractArticlePDF–10M
11.
Confirmation of FZD5 implication in a cohort of 50 patients with ocular coloboma
Marion Aubert-Mucca, Julie Pernin-Grandjean, Sébastien Marchasson, Veronique Gaston, Christophe Habib, Isabelle Meunier, Sabine Sigaudy, Josseline Kaplan, Olivier Roche, Danièle Denis, Pierre Bitoun, Damien Haye, Alain Verloes, Patrick Calvas, Nicolas Chassaing, Julie Plaisancié
Eur J Hum Genet. 2021 Jan; 29(1): 131–140. Published online 2020 Jul 31. doi: 10.1038/s41431-020-0695-8
PMCID:
PMC7853074
AbstractArticlePDF–659K
12.
FZD5 contributes to TNBC proliferation, DNA damage repair and stemness
Yu Sun, Zhuo Wang, Lei Na, Dan Dong, Wei Wang, Chenghai Zhao
Cell Death Dis. 2020 Dec; 11(12): 1060. Published online 2020 Dec 12. doi: 10.1038/s41419-020-03282-3
PMCID:
PMC7733599
AbstractArticlePDF–3.2M
13.
TMEM79/MATTRIN defines a pathway for Frizzled regulation and is required for Xenopus embryogenesis
Maorong Chen, Nathalia Amado, Jieqiong Tan, Alice Reis, Mengxu Ge, Jose Garcia Abreu, Xi He
eLife. 2020; 9: e56793. Published online 2020 Sep 14. doi: 10.7554/eLife.56793
PMCID:
PMC7521923
AbstractArticlePDF–7.4M
14.
Structure of human Frizzled5 by fiducial-assisted cryo-EM supports a heterodimeric mechanism of canonical Wnt signaling
Naotaka Tsutsumi, Somnath Mukherjee, Deepa Waghray, Claudia Y Janda, Kevin M Jude, Yi Miao, John S Burg, Nanda Gowtham Aduri, Anthony A Kossiakoff, Cornelius Gati, K Christopher Garcia
eLife. 2020; 9: e58464. Published online 2020 Aug 7. doi: 10.7554/eLife.58464
PMCID:
PMC7442489
AbstractArticlePDF–4.9M
15.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
16.
Upregulation of FZD5 in Eosinophilic Chronic Rhinosinusitis with Nasal Polyps by Epigenetic Modification
Jong-Yeup Kim, Min-Ji Cha, Young-Seon Park, Jaeku Kang, Jong-Joong Choi, Seung Min In, Dong-Kyu Kim
Mol Cells. 2019 Apr; 42(4): 345–355. Published online 2019 Apr 2. doi: 10.14348/molcells.2019.2418
PMCID:
PMC6530644
AbstractArticlePDF–3.6M
17.
Oligomerization of Frizzled and LRP5/6 protein initiates intracellular signaling for the canonical WNT/β-catenin pathway
Yue Hua, Yilin Yang, Qian Li, Xinyu He, Wei Zhu, Jiyong Wang, Xiaoqing Gan
J Biol Chem. 2018 Dec 21; 293(51): 19710–19724. Published online 2018 Oct 25. doi: 10.1074/jbc.RA118.004434
PMCID:
PMC6314125
AbstractArticlePDF–4.2M
18.
Structural basis for recognition of frizzled proteins by Clostridium difficile toxin B
Peng Chen, Liang Tao, Tianyu Wang, Jie Zhang, Aina He, Kwok-ho Lam, Zheng Liu, Xi He, Kay Perry, Min Dong, Rongsheng Jin
Science. Author manuscript; available in PMC 2019 May 11.
Published in final edited form as: Science. 2018 May 11; 360(6389): 664–669. doi: 10.1126/science.aar1999
PMCID:
PMC6231499
AbstractArticlePDF–2.3M
19.
Endothelial loss of Fzd5 stimulates PKC/Ets1-mediated transcription of Angpt2 and Flt1
Maarten M. Brandt, Christian G. M. van Dijk, Ihsan Chrifi, Heleen M. Kool, Petra E. Bürgisser, Laura Louzao-Martinez, Jiayi Pei, Robbert J. Rottier, Marianne C. Verhaar, Dirk J. Duncker, Caroline Cheng
Angiogenesis. 2018; 21(4): 805–821. Published online 2018 May 29. doi: 10.1007/s10456-018-9625-6
PMCID:
PMC6208898
AbstractArticlePDF–14M
20.
VIRMA mediates preferential m6A mRNA methylation in 3′UTR and near stop codon and associates with alternative polyadenylation
Yanan Yue, Jun Liu, Xiaolong Cui, Jie Cao, Guanzheng Luo, Zezhou Zhang, Tao Cheng, Minsong Gao, Xiao Shu, Honghui Ma, Fengqin Wang, Xinxia Wang, Bin Shen, Yizhen Wang, Xinhua Feng, Chuan He, Jianzhao Liu
Cell Discov. 2018; 4: 10. Published online 2018 Feb 27. doi: 10.1038/s41421-018-0019-0
PMCID:
PMC5826926
AbstractArticlePDF–2.3M

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