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Items: 1 to 20 of 42

1.
DSS1 restrains BRCA2’s engagement with dsDNA for homologous recombination, replication fork protection, and R-loop homeostasis
Yuxin Huang, Wenjing Li, Tzeh Foo, Jae-Hoon Ji, Bo Wu, Nozomi Tomimatsu, Qingming Fang, Boya Gao, Melissa Long, Jingfei Xu, Rouf Maqbool, Bipasha Mukherjee, Tengyang Ni, Salvador Alejo, Yuan He, Sandeep Burma, Li Lan, Bing Xia, Weixing Zhao
Nat Commun. 2024; 15: 7081. Published online 2024 Aug 17. doi: 10.1038/s41467-024-51557-6
PMCID:
PMC11329725
AbstractArticlePDF–3.7M
2.
OpenCell: proteome-scale endogenous tagging enables the cartography of human cellular organization
Nathan H. Cho, Keith C. Cheveralls, Andreas-David Brunner, Kibeom Kim, André C. Michaelis, Preethi Raghavan, Hirofumi Kobayashi, Laura Savy, Jason Y. Li, Hera Canaj, James Y.S. Kim, Edna M. Stewart, Christian Gnann, Frank McCarthy, Joana P. Cabrera, Rachel M. Brunetti, Bryant B. Chhun, Greg Dingle, Marco Y. Hein, Bo Huang, Shalin B. Mehta, Jonathan S. Weissman, Rafael Gómez-Sjöberg, Daniel N. Itzhak, Loic A. Royer, Matthias Mann, Manuel D. Leonetti
Science. Author manuscript; available in PMC 2022 Sep 11.
Published in final edited form as: Science. 2022 Mar 11; 375(6585): eabi6983. Published online 2022 Mar 11. doi: 10.1126/science.abi6983
PMCID:
PMC9119736
AbstractArticlePDF–3.3M
3.
Mammalian Ddi2 is a shuttling factor containing a retroviral protease domain that influences binding of ubiquitylated proteins and proteasomal degradation
Galen Andrew Collins, Zhe Sha, Chueh-Ling Kuo, Beyza Erbil, Alfred L. Goldberg
J Biol Chem. 2022 May; 298(5): 101875. Published online 2022 Mar 28. doi: 10.1016/j.jbc.2022.101875
PMCID:
PMC9062259
AbstractArticlePDF–1.7M
4.
An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity
Yuehui Zhang, Limin Shang, Jing Zhang, Yuchen Liu, Chaozhi Jin, Yanan Zhao, Xiaobo Lei, Wenjing Wang, Xia Xiao, Xiuyuan Zhang, Yujiao Liu, Linlin Liu, Meng-Wei Zhuang, Qingkun Mi, Chunyan Tian, Jianwei Wang, Fuchu He, Pei-Hui Wang, Jian Wang
Cell Chem Biol. 2022 Jan 20; 29(1): 5–18.e6. Published online 2021 Oct 20. doi: 10.1016/j.chembiol.2021.10.008
PMCID:
PMC8527578
AbstractArticlePDF–4.5M
5.
The disordered PCI‐binding human proteins CSNAP and DSS1 have diverged in structure and function
Sarah F. Ruidiaz, Jesper E. Dreier, Rasmus Hartmann‐Petersen, Birthe B. Kragelund
Protein Sci. 2021 Oct; 30(10): 2069–2082. Published online 2021 Jul 26. doi: 10.1002/pro.4159
PMCID:
PMC8442969
AbstractArticlePDF–2.5M
6.
Integrative oncogene-dependency mapping identifies RIT1 vulnerabilities and synergies in lung cancer
Athea Vichas, Amanda K. Riley, Naomi T. Nkinsi, Shriya Kamlapurkar, Phoebe C. R. Parrish, April Lo, Fujiko Duke, Jennifer Chen, Iris Fung, Jacqueline Watson, Matthew Rees, Austin M. Gabel, James D. Thomas, Robert K. Bradley, John K. Lee, Emily M. Hatch, Marina K. Baine, Natasha Rekhtman, Marc Ladanyi, Federica Piccioni, Alice H. Berger
Nat Commun. 2021; 12: 4789. Published online 2021 Aug 9. doi: 10.1038/s41467-021-24841-y
PMCID:
PMC8352964
AbstractArticlePDF–4.5M
7.
Cancer-causing BRCA2 missense mutations disrupt an intracellular protein assembly mechanism to disable genome maintenance
Miyoung Lee, David Shorthouse, Robert Mahen, Benjamin A Hall, Ashok R Venkitaraman
Nucleic Acids Res. 2021 Jun 4; 49(10): 5588–5604. Published online 2021 May 12. doi: 10.1093/nar/gkab308
PMCID:
PMC8191791
AbstractArticlePDF–2.3M
8.
DSS1 and ssDNA regulate oligomerization of BRCA2
Hang Phuong Le, Xiaoyan Ma, Jorge Vaquero, Megan Brinkmeyer, Fei Guo, Wolf-Dietrich Heyer, Jie Liu
Nucleic Acids Res. 2020 Aug 20; 48(14): 7818–7833. Published online 2020 Jul 1. doi: 10.1093/nar/gkaa555
PMCID:
PMC7641332
AbstractArticlePDF–5.1M
9.
RIG-I regulates myeloid differentiation by promoting TRIM25-mediated ISGylation
Song-Fang Wu, Li Xia, Xiao-Dong Shi, Yu-Jun Dai, Wei-Na Zhang, Jun-Mei Zhao, Wu Zhang, Xiang-Qin Weng, Jing Lu, Huang-Ying Le, Sheng-ce Tao, Jiang Zhu, Zhu Chen, Yue-Ying Wang, Saijuan Chen
Proc Natl Acad Sci U S A. 2020 Jun 23; 117(25): 14395–14404. Published online 2020 Jun 8. doi: 10.1073/pnas.1918596117
PMCID:
PMC7322067
AbstractArticlePDF–2.7M
10.
A reference map of the human binary protein interactome
Katja Luck, Dae-Kyum Kim, Luke Lambourne, Kerstin Spirohn, Bridget E. Begg, Wenting Bian, Ruth Brignall, Tiziana Cafarelli, Francisco J. Campos-Laborie, Benoit Charloteaux, Dongsic Choi, Atina G. Coté, Meaghan Daley, Steven Deimling, Alice Desbuleux, Amélie Dricot, Marinella Gebbia, Madeleine F. Hardy, Nishka Kishore, Jennifer J. Knapp, István A. Kovács, Irma Lemmens, Miles W. Mee, Joseph C. Mellor, Carl Pollis, Carles Pons, Aaron D. Richardson, Sadie Schlabach, Bridget Teeking, Anupama Yadav, Mariana Babor, Dawit Balcha, Omer Basha, Christian Bowman-Colin, Suet-Feung Chin, Soon Gang Choi, Claudia Colabella, Georges Coppin, Cassandra D’Amata, David De Ridder, Steffi De Rouck, Miquel Duran-Frigola, Hanane Ennajdaoui, Florian Goebels, Liana Goehring, Anjali Gopal, Ghazal Haddad, Elodie Hatchi, Mohamed Helmy, Yves Jacob, Yoseph Kassa, Serena Landini, Roujia Li, Natascha van Lieshout, Andrew MacWilliams, Dylan Markey, Joseph N. Paulson, Sudharshan Rangarajan, John Rasla, Ashyad Rayhan, Thomas Rolland, Adriana San-Miguel, Yun Shen, Dayag Sheykhkarimli, Gloria M. Sheynkman, Eyal Simonovsky, Murat Taşan, Alexander Tejeda, Vincent Tropepe, Jean-Claude Twizere, Yang Wang, Robert J. Weatheritt, Jochen Weile, Yu Xia, Xinping Yang, Esti Yeger-Lotem, Quan Zhong, Patrick Aloy, Gary D. Bader, Javier De Las Rivas, Suzanne Gaudet, Tong Hao, Janusz Rak, Jan Tavernier, David E. Hill, Marc Vidal, Frederick P. Roth, Michael A. Calderwood
Nature. Author manuscript; available in PMC 2020 Oct 8.
Published in final edited form as: Nature. 2020 Apr; 580(7803): 402–408. Published online 2020 Apr 8. doi: 10.1038/s41586-020-2188-x
PMCID:
PMC7169983
AbstractArticlePDF–5.4M
11.
DSS1 interacts with and stimulates RAD52 to promote the repair of DSBs
Barbora Stefanovie, Sarah R Hengel, Jarmila Mlcouskova, Jana Prochazkova, Mario Spirek, Fedor Nikulenkov, Daniel Nemecek, Brandon G Koch, Fletcher E Bain, Liping Yu, Maria Spies, Lumir Krejci
Nucleic Acids Res. 2020 Jan 24; 48(2): 694–708. Published online 2019 Dec 4. doi: 10.1093/nar/gkz1052
PMCID:
PMC6954417
AbstractArticlePDF–4.6M
12.
Structural mechanism for nucleotide-driven remodeling of the AAA-ATPase unfoldase in the activated human 26S proteasome
Yanan Zhu, Wei Li Wang, Daqi Yu, Qi Ouyang, Ying Lu, Youdong Mao
Nat Commun. 2018; 9: 1360. Published online 2018 Apr 10. doi: 10.1038/s41467-018-03785-w
PMCID:
PMC5893597
AbstractArticlePDF–7.4M
13.
Promotion of RAD51-mediated homologous DNA pairing by BRCA1-BARD1
Weixing Zhao, Justin B. Steinfeld, Fengshan Liang, Xiaoyong Chen, David G. Maranon, Chu Jian Ma, Youngho Kwon, Timsi Rao, Weibin Wang, Sheng Chen, Xuemei Song, Yanhong Deng, Judit Jimenez-Sainz, Lucy Lu, Ryan B. Jensen, Yong Xiong, Gary M. Kupfer, Claudia Wiese, Eric C. Greene, Patrick Sung
Nature. Author manuscript; available in PMC 2018 Apr 19.
Published in final edited form as: Nature. 2017 Oct 19; 550(7676): 360–365. Published online 2017 Oct 4. doi: 10.1038/nature24060
PMCID:
PMC5800781
AbstractArticlePDF–4.3M
14.
Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c
Chueh-Ling Kuo, Alfred Lewis Goldberg
Proc Natl Acad Sci U S A. 2017 Apr 25; 114(17): E3404–E3413. Published online 2017 Apr 10. doi: 10.1073/pnas.1701734114
PMCID:
PMC5410784
AbstractArticlePDF–1.9M
15.
Non-catalytic Roles For XPG with BRCA1 and BRCA2 in Homologous Recombination and Genome Stability
Kelly S. Trego, Torsten Groesser, Albert R. Davalos, Ann C. Parplys, Weixing Zhao, Michael R. Nelson, Ayesu Hlaing, Brian Shih, Björn Rydberg, Janice M. Pluth, Miaw-Sheue Tsai, Jan H.J. Hoeijmakers, Patrick Sung, Claudia Wiese, Judith Campisi, Priscilla K. Cooper
Mol Cell. Author manuscript; available in PMC 2017 Feb 18.
Published in final edited form as: Mol Cell. 2016 Feb 18; 61(4): 535–546. Published online 2016 Jan 28. doi: 10.1016/j.molcel.2015.12.026
PMCID:
PMC4761302
AbstractArticlePDF–971K
16.
Promotion of BRCA2-dependent Homologous Recombination by DSS1 via RPA Targeting and DNA Mimicry
Weixing Zhao, Sivaraja Vaithiyalingam, Joseph San Filippo, David G. Maranon, Judit Jimenez-Sainz, Gerald V. Fontenay, Youngho Kwon, Stanley G. Leung, Lucy Lu, Ryan B. Jensen, Walter J. Chazin, Claudia Wiese, Patrick Sung
Mol Cell. Author manuscript; available in PMC 2016 Jul 16.
Published in final edited form as: Mol Cell. 2015 Jul 16; 59(2): 176–187. Published online 2015 Jul 2. doi: 10.1016/j.molcel.2015.05.032
PMCID:
PMC4506714
AbstractArticlePDF–1.8M
17.
The Contribution of Common Genetic Variation to Nicotine and Cotinine Glucuronidation in Multiple Ethnic/Racial Populations
Yesha M. Patel, Daniel O. Stram, Lynne R. Wilkens, Sung-Shim L. Park, Brian E. Henderson, Loic Le Marchand, Christopher A. Haiman, Sharon E. Murphy
Cancer Epidemiol Biomarkers Prev. Author manuscript; available in PMC 2016 Jan 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2015 Jan; 24(1): 119–127. Published online 2014 Oct 7. doi: 10.1158/1055-9965.EPI-14-0815
PMCID:
PMC4294952
AbstractArticlePDF–590K
18.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
19.
Breast cancers with high DSS1 expression that potentially maintains BRCA2 stability have poor prognosis in the relapse-free survival
Andri Rezano, Kazuhiko Kuwahara, Mutsuko Yamamoto-Ibusuki, Masahiro Kitabatake, Penpak Moolthiya, Suchada Phimsen, Taiji Suda, Shigenobu Tone, Yutaka Yamamoto, Hirotaka Iwase, Nobuo Sakaguchi
BMC Cancer. 2013; 13: 562. Published online 2013 Dec 1. doi: 10.1186/1471-2407-13-562
PMCID:
PMC4219476
AbstractArticlePDF–2.1M
20.
Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates
Henrike C Besche, Zhe Sha, Nikolay V Kukushkin, Andreas Peth, Eva-Maria Hock, Woong Kim, Steven Gygi, Juan A Gutierrez, Hua Liao, Lawrence Dick, Alfred L Goldberg
EMBO J. 2014 May 16; 33(10): 1159–1176. Published online 2014 May 8. doi: 10.1002/embj.201386906
PMCID:
PMC4193922
AbstractArticlePDF–1.1M

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