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Select item 102562351.

A worm’s life: AMPK links muscle mitochondrial dynamics to physical fitness and healthy aging in Caenorhabditis elegans

Vihang A. Narkar

J Cardiovasc Aging. Author manuscript; available in PMC 2023 Jun 9.

Published in final edited form as: J Cardiovasc Aging. 2023; 3(3): 25. Published online 2023 May 4. doi: 10.20517/jca.2023.14

PMCID:: PMC10256235

Article PDF–237K

Select item 102286502.

Endosomal trafficking protein TBC-2 is required for the longevity of long-lived mitochondrial mutants

Annika Traa, Hazel Shields, Abdelrahman AlOkda, Zenith D. Rudich, Bokang Ko, Jeremy M. Van Raamsdonk

Front Aging. 2023; 4: 1145198. Published online 2023 May 16. doi: 10.3389/fragi.2023.1145198

PMCID:: PMC10228650

Abstract Article PDF–2.2M

Select item 99262783.

Exercise preserves physical fitness during aging through AMPK and mitochondrial dynamics

Juliane Cruz Campos, Luiz Henrique Marchesi Bozi, Barbara Krum, Luiz Roberto Grassmann Bechara, Nikolas Dresch Ferreira, Gabriel Santos Arini, Rudá Prestes Albuquerque, Annika Traa, Takafumi Ogawa, Alexander M. van der Bliek, Afshin Beheshti, Edward T. Chouchani, Jeremy M. Van Raamsdonk, T. Keith Blackwell, Julio Cesar Batista Ferreira

Proc Natl Acad Sci U S A. 2023 Jan 10; 120(2): e2204750120. Published online 2023 Jan 3. doi: 10.1073/pnas.2204750120

PMCID:: PMC9926278

Abstract Article PDF–5.4M

Select item 97108734.

Stimulation of RAS-dependent ROS signaling extends longevity by modulating a developmental program of global gene expression

Robyn Branicky, Ying Wang, Arman Khaki, Ju-Ling Liu, Maximilian Kramer-Drauberg, Siegfried Hekimi

Sci Adv. 2022 Dec; 8(48): eadc9851. Published online 2022 Nov 30. doi: 10.1126/sciadv.adc9851

PMCID:: PMC9710873

Abstract Article PDF–2.2M

Select item 94378485.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 91707836.

SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells

Joshua Jackson, Lena Wischhof, Enzo Scifo, Anna Pellizzer, Yiru Wang, Antonia Piazzesi, Debora Gentile, Sana Siddig, Miriam Stork, Chris E. Hopkins, Kristian Händler, Joachim Weis, Andreas Roos, Joachim L. Schultze, Pierluigi Nicotera, Dan Ehninger, Daniele Bano

Mol Metab. 2022 Jul; 61: 101503. Published online 2022 Apr 19. doi: 10.1016/j.molmet.2022.101503

PMCID:: PMC9170783

Abstract Article PDF–3.7M

Select item 91269547.

Mitochondrial thioredoxin system is required for enhanced stress resistance and extended longevity in long-lived mitochondrial mutants

Namastheé Harris-Gauthier, Annika Traa, Abdelrahman AlOkda, Alibek Moldakozhayev, Ulrich Anglas, Sonja K. Soo, Jeremy M. Van Raamsdonk

Redox Biol. 2022 Jul; 53: 102335. Published online 2022 May 13. doi: 10.1016/j.redox.2022.102335

PMCID:: PMC9126954

Abstract Article PDF–8.9M

Select item 90660748.

CEST‐2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutants

Antonia Piazzesi, Yiru Wang, Joshua Jackson, Lena Wischhof, Viktoria Zeisler‐Diehl, Enzo Scifo, Ina Oganezova, Thorben Hoffmann, Pablo Gómez Martín, Fabio Bertan, Chester J J Wrobel, Frank C Schroeder, Dan Ehninger, Kristian Händler, Joachim L Schultze, Lukas Schreiber, Gerhild van Echten‐Deckert, Pierluigi Nicotera, Daniele Bano

EMBO Rep. 2022 May; 23(5): e52606. Published online 2022 Mar 17. doi: 10.15252/embr.202152606

PMCID:: PMC9066074

Abstract Article PDF–4.8M

Select item 90642979.

A tRNA processing enzyme is a key regulator of the mitochondrial unfolded protein response

James P Held, Gaomin Feng, Benjamin R Saunders, Claudia V Pereira, Kristopher Burkewitz, Maulik R Patel

eLife. 2022; 11: e71634. Published online 2022 Apr 22. doi: 10.7554/eLife.71634

PMCID:: PMC9064297

Abstract Article PDF–4.6M

Select item 875312210.

Gene regulatory network inference in long-lived C. elegans reveals modular properties that are predictive of novel aging genes

Manusnan Suriyalaksh, Celia Raimondi, Abraham Mains, Anne Segonds-Pichon, Shahzabe Mukhtar, Sharlene Murdoch, Rebeca Aldunate, Felix Krueger, Roger Guimerà, Simon Andrews, Marta Sales-Pardo, Olivia Casanueva

iScience. 2022 Jan 21; 25(1): 103663. Published online 2021 Dec 20. doi: 10.1016/j.isci.2021.103663

PMCID:: PMC8753122

Abstract Article PDF–4.6M

Select item 833118311.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 799517612.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 773567913.

Mitochondrial dysfunction induces RNA interference in C. elegans through a pathway homologous to the mammalian RIG-I antiviral response

Kai Mao, Peter Breen, Gary Ruvkun

PLoS Biol. 2020 Dec; 18(12): e3000996. Published online 2020 Dec 2. doi: 10.1371/journal.pbio.3000996

PMCID:: PMC7735679

Abstract Article PDF–2.2M

Select item 731934214.

ROS regulation of RAS and vulva development in Caenorhabditis elegans

Maximilian Kramer-Drauberg, Ju-Ling Liu, David Desjardins, Ying Wang, Robyn Branicky, Siegfried Hekimi

PLoS Genet. 2020 Jun; 16(6): e1008838. Published online 2020 Jun 16. doi: 10.1371/journal.pgen.1008838

PMCID:: PMC7319342

Abstract Article PDF–2.5M

Select item 725231315.

Caenorhabditis elegans strain sensitivity to sodium arsenite exposure is varied based on age and outcome measured

Kathleen A Hershberger, Tess C Leuthner, Tanner A Waters, Joel N Meyer

MicroPubl Biol. 2019; 2019: 10.17912/micropub.biology.000186. Published online 2019 Oct 22. doi: 10.17912/micropub.biology.000186

PMCID:: PMC7252313

Article PDF–150K

Select item 682614516.

The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans

Stefanie Müthel, Bora Uyar, Mei He, Anne Krause, Burcu Vitrinel, Selman Bulut, Djordje Vasiljevic, Iris Marchal, Stefan Kempa, Altuna Akalin, Baris Tursun

Aging Cell. 2019 Dec; 18(6): e13012. Published online 2019 Aug 9. doi: 10.1111/acel.13012

PMCID:: PMC6826145

Abstract Article PDF–3.0M

Select item 629812617.

Mitochondrial unfolded protein response transcription factor ATFS-1 promotes longevity in a long-lived mitochondrial mutant through activation of stress response pathways

Ziyun Wu, Megan M. Senchuk, Dylan J. Dues, Benjamin K. Johnson, Jason F. Cooper, Leira Lew, Emily Machiela, Claire E. Schaar, Heather DeJonge, T. Keith Blackwell, Jeremy M. Van Raamsdonk

BMC Biol. 2018; 16: 147. Published online 2018 Dec 18. doi: 10.1186/s12915-018-0615-3