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Select item 104233191.

53bp1 mutation enhances brca1 and bard1 embryonic lethality in C. elegans

Sara Hariri, Qianyan Li, JoAnne Engebrecht

MicroPubl Biol. 2023; 2023: 10.17912/micropub.biology.000934. Published online 2023 Jul 29. doi: 10.17912/micropub.biology.000934

PMCID:: PMC10423319

Abstract Article PDF–488K

Select item 103207662.

A transcriptional cofactor regulatory network for the C. elegans intestine

Brent B Horowitz, Shivani Nanda, Albertha J M Walhout

G3 (Bethesda) 2023 Jul; 13(7): jkad096. Published online 2023 Apr 29. doi: 10.1093/g3journal/jkad096

PMCID:: PMC10320766

Abstract Article PDF–1.9M

Select item 101131563.

The DREAM complex functions as conserved master regulator of somatic DNA-repair capacities

Arturo Bujarrabal-Dueso, Georg Sendtner, David H. Meyer, Georgia Chatzinikolaou, Kalliopi Stratigi, George A. Garinis, Björn Schumacher

Nat Struct Mol Biol. 2023; 30(4): 475–488. Published online 2023 Mar 23. doi: 10.1038/s41594-023-00942-8

PMCID:: PMC10113156

Abstract Article PDF–13M

Select item 100183404.

Conservation of transcriptional regulation by BRCA1 and BARD1 in Caenorhabditis elegans

Ishor Thapa, Russell Vahrenkamp, Samuel R Witus, Caitlin Lightle, Owen Falkenberg, Marlo K Sellin Jeffries, Rachel E Klevit, Mikaela D Stewart

Nucleic Acids Res. 2023 Mar 21; 51(5): 2108–2116. Published online 2022 Oct 17. doi: 10.1093/nar/gkac877

PMCID:: PMC10018340

Abstract Article PDF–1.3M

Select item 99107975.

Differential requirement for BRCA1-BARD1 E3 ubiquitin ligase activity in DNA damage repair and meiosis in the Caenorhabditis elegans germ line

Qianyan Li, Arshdeep Kaur, Kyoko Okada, Richard J. McKenney, JoAnne Engebrecht

PLoS Genet. 2023 Jan; 19(1): e1010457. Published online 2023 Jan 30. doi: 10.1371/journal.pgen.1010457

PMCID:: PMC9910797

Abstract Article PDF–3.6M

Select item 98340566.

Inheritance of paternal DNA damage by histone-mediated repair restriction

Siyao Wang, David H. Meyer, Björn Schumacher

Nature. 2023; 613(7943): 365–374. Published online 2022 Dec 21. doi: 10.1038/s41586-022-05544-w

PMCID:: PMC9834056

Abstract Article PDF–23M

Select item 98183717.

Transcriptomic Analysis Reveals JAK2/MPL-Independent Effects of Calreticulin Mutations in a C. elegans Model

Ana Guijarro-Hernández, Laura Eder-Azanza, Cristina Hurtado, David Navarro-Herrera, Begoña Ezcurra, Francisco Javier Novo, Juan Cabello, José Luis Vizmanos

Cells. 2023 Jan; 12(1): 186. Published online 2023 Jan 2. doi: 10.3390/cells12010186

PMCID:: PMC9818371

Abstract Article PDF–3.8M

Select item 97570428.

PARG and BRCA1–BARD1 cooperative function regulates DNA repair pathway choice during gametogenesis

Shalini Trivedi, Jitka Blazícková, Nicola Silva

Nucleic Acids Res. 2022 Nov 28; 50(21): 12291–12308. Published online 2022 Dec 8. doi: 10.1093/nar/gkac1153

PMCID:: PMC9757042

Abstract Article PDF–25M

Select item 86549639.

Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications

J. A. Kamp, B. B. L. G. Lemmens, R. J. Romeijn, S. C. Changoer, R. van Schendel, M. Tijsterman

Nat Commun. 2021; 12: 7126. Published online 2021 Dec 8. doi: 10.1038/s41467-021-27408-z

PMCID:: PMC8654963

Abstract Article PDF–1.0M

Select item 862747910.

Analysis of representative mutants for key DNA repair pathways on healthspan in Caenorhabditis elegans

Lucile Marchal, Shruthi Hamsanathan, Roshan Karthikappallil, Suhao Han, Himaly Shinglot, Aditi U. Gurkar

Mech Ageing Dev. Author manuscript; available in PMC 2022 Dec 1.

Published in final edited form as: Mech Ageing Dev. 2021 Dec; 200: 111573. Published online 2021 Sep 22. doi: 10.1016/j.mad.2021.111573

PMCID:: PMC8627479

Abstract Article PDF–1.2M

Select item 807882111.

Protection of the C. elegans germ cell genome depends on diverse DNA repair pathways during normal proliferation

Bettina Meier, Nadezda V. Volkova, Ye Hong, Simone Bertolini, Víctor González-Huici, Tsvetana Petrova, Simon Boulton, Peter J. Campbell, Moritz Gerstung, Anton Gartner

PLoS One. 2021; 16(4): e0250291. Published online 2021 Apr 27. doi: 10.1371/journal.pone.0250291

PMCID:: PMC8078821

Abstract Article PDF–2.7M

Select item 802521512.

DNA topoisomerase 3 is required for efficient germ cell quality control

Maria Rosaria Dello Stritto, Bernd Bauer, Pierre Barraud, Verena Jantsch

J Cell Biol. 2021 Jun 7; 220(6): e202012057. Published online 2021 Apr 2. doi: 10.1083/jcb.202012057

PMCID:: PMC8025215

Abstract Article PDF–6.3M

Select item 801889713.

BRCA1–BARD1 Regulates Axon Regeneration in Concert with the Gqα–DAG Signaling Network

Yoshiki Sakai, Hiroshi Hanafusa, Tatsuhiro Shimizu, Strahil I. Pastuhov, Naoki Hisamoto, Kunihiro Matsumoto

J Neurosci. 2021 Mar 31; 41(13): 2842–2853. doi: 10.1523/JNEUROSCI.1806-20.2021

PMCID:: PMC8018897

Abstract Article PDF–2.4M

Select item 770862014.

Functional characterization of Caenorhabditis elegans cbs-2 gene during meiosis

Pamela Santonicola, Marcello Germoglio, Domenico Scotto d’Abbusco, Adele Adamo

Sci Rep. 2020; 10: 20913. Published online 2020 Dec 1. doi: 10.1038/s41598-020-78006-w

PMCID:: PMC7708620

Abstract Article PDF–5.0M

Select item 753685315.

Meiotic Double-Strand Break Processing and Crossover Patterning Are Regulated in a Sex-Specific Manner by BRCA1–BARD1 in Caenorhabditis elegans

Qianyan Li, Sara Hariri, JoAnne Engebrecht

Genetics. 2020 Oct; 216(2): 359–379. Published online 2020 Aug 12. doi: 10.1534/genetics.120.303292

PMCID:: PMC7536853

Abstract Article PDF–2.7M

Select item 744780316.

DEPS-1 is required for piRNA-dependent silencing and PIWI condensate organisation in Caenorhabditis elegans

Kin Man Suen, Fabian Braukmann, Richard Butler, Dalila Bensaddek, Alper Akay, Chi-Chuan Lin, Dovilė Milonaitytė, Neel Doshi, Alexandra Sapetschnig, Angus Lamond, John Edward Ladbury, Eric Alexander Miska

Nat Commun. 2020; 11: 4242. Published online 2020 Aug 25. doi: 10.1038/s41467-020-18089-1

PMCID:: PMC7447803

Abstract Article PDF–2.3M

Select item 736803617.

BRCA1-associated structural variations are a consequence of polymerase theta-mediated end-joining

J. A. Kamp, R. van Schendel, I. W. Dilweg, M. Tijsterman

Nat Commun. 2020; 11: 3615. Published online 2020 Jul 17. doi: 10.1038/s41467-020-17455-3

PMCID:: PMC7368036

Abstract Article PDF–885K

Select item 695243718.

In vivo analysis of FANCD2 recruitment at meiotic DNA breaks in Caenorhabditis elegans

Marcello Germoglio, Anna Valenti, Ines Gallo, Chiara Forenza, Pamela Santonicola, Nicola Silva, Adele Adamo

Sci Rep. 2020; 10: 103. Published online 2020 Jan 9. doi: 10.1038/s41598-019-57096-1

PMCID:: PMC6952437

Abstract Article PDF–4.7M

Select item 633422719.

A Meiotic Checkpoint Alters Repair Partner Bias to Permit Inter-sister Repair of Persistent DSBs

Tatiana Garcia-Muse, U. Galindo-Diaz, M. Garcia-Rubio, J.S. Martin, J. Polanowska, N. O’Reilly, A. Aguilera, Simon J. Boulton

Cell Rep. 2019 Jan 15; 26(3): 775–787.e5. Published online 2019 Jan 15. doi: 10.1016/j.celrep.2018.12.074

PMCID:: PMC6334227

Abstract Article PDF–4.7M

Select item 628079720.

BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans

Alessandro Torgovnick, Alfonso Schiavi, Anjumara Shaik, Henok Kassahun, Silvia Maglioni, Shane L Rea, Thomas E Johnson, Hans C Reinhardt, Sebastian Honnen, Björn Schumacher, Hilde Nilsen, Natascia Ventura

EMBO Rep. 2018 Dec; 19(12): e45856. Published online 2018 Oct 26. doi: 10.15252/embr.201845856