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Select item 111574841.

2-Butoxytetrahydrofuran, Isolated from Holothuria scabra, Attenuates Aggregative and Oxidative Properties of α-Synuclein and Alleviates Its Toxicity in a Transgenic Caenorhabditis elegans Model of Parkinson’s Disease

Sukrit Promtang, Tanatcha Sanguanphun, Pawanrat Chalorak, Laurence S. Pe, Nakorn Niamnont, Prasert Sobhon, Krai Meemon

ACS Chem Neurosci. 2024 Jun 5; 15(11): 2182–2197. Published online 2024 May 10. doi: 10.1021/acschemneuro.4c00008

PMCID:: PMC11157484

Abstract Article PDF–8.0M

Select item 110227502.

Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons

Yongzhi Yang, Meghan Lee Arnold, Caitlin M. Lange, Ling-Hsuan Sun, Michael Broussalian, Saam Doroodian, Hiroshi Ebata, Elizabeth H. Choy, Karie Poon, Tatiana M. Moreno, Anupama Singh, Monica Driscoll, Caroline Kumsta, Malene Hansen

Nat Aging. Author manuscript; available in PMC 2024 Apr 17.

Published in final edited form as: Nat Aging. 2024 Feb; 4(2): 198–212. Published online 2024 Jan 4. doi: 10.1038/s43587-023-00548-1

PMCID:: PMC11022750

Abstract Article PDF–4.4M

Select item 93580633.

Ginseng volatile oil prolongs the lifespan and healthspan of Caenorhabditis elegans

Lixin Wang, Ping Qiao, Zhuoer Ouyang, Danyang Li, Jingtong Zheng, Guoqiang Wang, Fang Wang

Biogerontology. 2022; 23(4): 485–497. Published online 2022 Aug 8. doi: 10.1007/s10522-022-09956-z

PMCID:: PMC9358063

Abstract Article PDF–1.9M

Select item 91336944.

Autophagy Regulation Influences β-Amyloid Toxicity in Transgenic Caenorhabditis elegans

Hongru Lin, Yehui Gao, Chen Zhang, Botian Ma, Mengchen Wu, Xianghuan Cui, Hongbing Wang

Front Aging Neurosci. 2022; 14: 885145. Published online 2022 May 12. doi: 10.3389/fnagi.2022.885145

PMCID:: PMC9133694

Abstract Article PDF–2.3M

Select item 89596025.

Nuclear hormone receptor NHR-49 acts in parallel with HIF-1 to promote hypoxia adaptation in Caenorhabditis elegans

Kelsie RS Doering, Xuanjin Cheng, Luke Milburn, Ramesh Ratnappan, Arjumand Ghazi, Dana L Miller, Stefan Taubert

eLife. 2022; 11: e67911. Published online 2022 Mar 14. doi: 10.7554/eLife.67911

PMCID:: PMC8959602

Abstract Article PDF–9.4M

Select item 86656456.

Variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy

Laura C Bott, Mitra Forouhan, Maria Lieto, Ambre J Sala, Ruth Ellerington, Janel O Johnson, Alfina A Speciale, Chiara Criscuolo, Alessandro Filla, David Chitayat, Ebba Alkhunaizi, Patrick Shannon, Andrea H Nemeth, Italian Undiagnosed Diseases Network , Francesco Angelucci, Wooi Fang Lim, Pasquale Striano, Federico Zara, Ingo Helbig, Mikko Muona, Carolina Courage, Anna-Elina Lehesjoki, Samuel F Berkovic, ATPase Consortium , Kenneth H Fischbeck, Francesco Brancati, Richard I Morimoto, Matthew J A Wood, Carlo Rinaldi

Brain Commun. 2021; 3(4): fcab245. Published online 2021 Oct 18. doi: 10.1093/braincomms/fcab245

PMCID:: PMC8665645

Abstract Article PDF–1.2M

Select item 83397137.

Muscle‐derived exophers promote reproductive fitness

Michał Turek, Katarzyna Banasiak, Małgorzata Piechota, Nilesh Shanmugam, Matylda Macias, Małgorzata Alicja Śliwińska, Marta Niklewicz, Konrad Kowalski, Natalia Nowak, Agnieszka Chacinska, Wojciech Pokrzywa

EMBO Rep. 2021 Aug 4; 22(8): e52071. Published online 2021 Jul 20. doi: 10.15252/embr.202052071

PMCID:: PMC8339713

Abstract Article PDF–2.6M

Select item 83311838.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 80040219.

Molecular Basis of Neuronal Autophagy in Ageing: Insights from Caenorhabditis elegans

Georgios Konstantinidis, Nektarios Tavernarakis

Cells. 2021 Mar; 10(3): 694. Published online 2021 Mar 21. doi: 10.3390/cells10030694

PMCID:: PMC8004021

Abstract Article PDF–1.0M

Select item 799517610.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 653428711.

Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans

Hyemin Min, Yong-Uk Lee, Yhong-Hee Shim, Ichiro Kawasaki

PLoS Genet. 2019 May; 15(5): e1008150. Published online 2019 May 24. doi: 10.1371/journal.pgen.1008150

PMCID:: PMC6534287

Abstract Article PDF–4.7M

Select item 621659012.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 579271513.

Autophagy and Longevity

Shuhei Nakamura, Tamotsu Yoshimori

Mol Cells. 2018 Jan 31; 41(1): 65–72. Published online 2018 Jan 23. doi: 10.14348/molcells.2018.2333

PMCID:: PMC5792715

Abstract Article PDF–741K

Select item 549447414.

Molecular definitions of autophagy and related processes

Lorenzo Galluzzi, Eric H Baehrecke, Andrea Ballabio, Patricia Boya, José Manuel Bravo‐San Pedro, Francesco Cecconi, Augustine M Choi, Charleen T Chu, Patrice Codogno, Maria Isabel Colombo, Ana Maria Cuervo, Jayanta Debnath, Vojo Deretic, Ivan Dikic, Eeva‐Liisa Eskelinen, Gian Maria Fimia, Simone Fulda, David A Gewirtz, Douglas R Green, Malene Hansen, J Wade Harper, Marja Jäättelä, Terje Johansen, Gabor Juhasz, Alec C Kimmelman, Claudine Kraft, Nicholas T Ktistakis, Sharad Kumar, Beth Levine, Carlos Lopez‐Otin, Frank Madeo, Sascha Martens, Jennifer Martinez, Alicia Melendez, Noboru Mizushima, Christian Münz, Leon O Murphy, Josef M Penninger, Mauro Piacentini, Fulvio Reggiori, David C Rubinsztein, Kevin M Ryan, Laura Santambrogio, Luca Scorrano, Anna Katharina Simon, Hans‐Uwe Simon, Anne Simonsen, Nektarios Tavernarakis, Sharon A Tooze, Tamotsu Yoshimori, Junying Yuan, Zhenyu Yue, Qing Zhong, Guido Kroemer

EMBO J. 2017 Jul 3; 36(13): 1811–1836. Published online 2017 Jun 8. doi: 10.15252/embj.201796697