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Select item 112535501.

PUF partner interactions at a conserved interface shape the RNA binding landscape and cell fate in Caenorhabditis elegans

Brian H. Carrick, Sarah L. Crittenden, Fan Chen, MaryGrace Linsley, Jennifer Woodworth, Peggy Kroll-Conner, Ahlan S. Ferdous, Sündüz Keleş, Marvin Wickens, Judith Kimble

Dev Cell. Author manuscript; available in PMC 2024 Jul 17.

Published in final edited form as: Dev Cell. 2024 Mar 11; 59(5): 661–675.e7. Published online 2024 Jan 29. doi: 10.1016/j.devcel.2024.01.005

PMCID:: PMC11253550

Abstract Article PDF–3.3M

Select item 112004322.

C. elegans Germline as Three Distinct Tumor Models

Mariah Jones, Mina Norman, Alex Minh Tiet, Jiwoo Lee, Myon Hee Lee

Biology (Basel) 2024 Jun; 13(6): 425. Published online 2024 Jun 8. doi: 10.3390/biology13060425

PMCID:: PMC11200432

Abstract Article PDF–3.8M

Select item 103207183.

The C. elegans gene gvd-1 promotes late larval development and germ cell proliferation

Anbalagan Pon Ezhil Buvani, Kuppuswamy Subramaniam

Biol Open. 2023 Jul 15; 12(7): bio059978. Published online 2023 Jun 30. doi: 10.1242/bio.059978

PMCID:: PMC10320718

Abstract Article PDF–8.4M

Select item 102869694.

Characterization of the biochemical activity and tumor-promoting role of the dual protein methyltransferase METL-13/METTL13 in Caenorhabditis elegans

Melanie L. Engelfriet, Jędrzej M. Małecki, Anna F. Forsberg, Pål Ø. Falnes, Rafal Ciosk

PLoS One. 2023; 18(6): e0287558. Published online 2023 Jun 22. doi: 10.1371/journal.pone.0287558

PMCID:: PMC10286969

Abstract Article PDF–2.1M

Select item 101513975.

Cryptic genetic variation of expression quantitative trait locus architecture revealed by genetic perturbation in Caenorhabditis elegans

Marijke H van Wijk, Joost A G Riksen, Mark Elvin, Gino B Poulin, Muhammad I Maulana, Jan E Kammenga, Basten L Snoek, Mark G Sterken

G3 (Bethesda) 2023 May; 13(5): jkad050. Published online 2023 Mar 2. doi: 10.1093/g3journal/jkad050

PMCID:: PMC10151397

Abstract Article PDF–760K

Select item 94486866.

Potent anticancer activity of a novel iridium metallodrug via oncosis

Enrique Ortega-Forte, Samanta Hernández-García, Gloria Vigueras, Paula Henarejos-Escudero, Natalia Cutillas, José Ruiz, Fernando Gandía-Herrero

Cell Mol Life Sci. 2022; 79(10): 510. Published online 2022 Sep 6. doi: 10.1007/s00018-022-04526-5

PMCID:: PMC9448686

Abstract Article PDF–4.2M

Select item 92000657.

Multi-modal regulation of C. elegans hermaphrodite spermatogenesis by the GLD-1-FOG-2 complex

Shuang Hu, Lauren E. Ryan, Ebru Kaymak, Lindsay Freeberg, Te-Wen Lo, Scott Kuersten, Sean P. Ryder, Eric S. Haag

Dev Biol. Author manuscript; available in PMC 2022 Jun 15.

Published in final edited form as: Dev Biol. 2019 Feb 15; 446(2): 193–205. Published online 2018 Dec 30. doi: 10.1016/j.ydbio.2018.11.024

PMCID:: PMC9200065

Abstract Article PDF–1.6M

Select item 90584968.

Notch-dependent DNA cis-regulatory elements and their dose-dependent control of C. elegans stem cell self-renewal

Tina R. Lynch, Mingyu Xue, Cazza W. Czerniak, ChangHwan Lee, Judith Kimble

Development. 2022 Apr 1; 149(7): dev200332. Published online 2022 Apr 8. doi: 10.1242/dev.200332

PMCID:: PMC9058496

Abstract Article

Select item 88493379.

Release of CHK-2 from PPM-1.D anchorage schedules meiotic entry

Antoine Baudrimont, Dimitra Paouneskou, Ariz Mohammad, Raffael Lichtenberger, Joshua Blundon, Yumi Kim, Markus Hartl, Sebastian Falk, Tim Schedl, Verena Jantsch

Sci Adv. 2022 Feb; 8(7): eabl8861. Published online 2022 Feb 16. doi: 10.1126/sciadv.abl8861

PMCID:: PMC8849337

Abstract Article PDF–7.2M

Select item 858932910.

Meiosis initiation: a story of two sexes in all creatures great and small

Ieng Fong Sou, Rebecca M. Pryce, Wee-Wei Tee, Urszula Lucja McClurg

Biochem J. 2021 Oct 29; 478(20): 3791–3805. Published online 2021 Oct 28. doi: 10.1042/BCJ20210412

PMCID:: PMC8589329

Abstract Article PDF–1.5M

Select item 812799611.

An improved in vivo tethering assay with single molecule FISH reveals that a nematode Nanos enhances reporter expression and mRNA stability

Jonathan Doenier, Tina R. Lynch, Judith Kimble, Scott T. Aoki

RNA. 2021 Jun; 27(6): 643–652. doi: 10.1261/rna.078693.121

PMCID:: PMC8127996

Abstract Article PDF–4.1M

Select item 799517612.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 771002313.

PLP-1 is essential for germ cell development and germline gene silencing in Caenorhabditiselegans

Rajaram Vishnupriya, Linitha Thomas, Lamia Wahba, Andrew Fire, Kuppuswamy Subramaniam

Development. 2020 Nov 15; 147(22): dev195578. Published online 2020 Nov 27. doi: 10.1242/dev.195578

PMCID:: PMC7710023

Abstract Article

Select item 760881114.

ERK phosphorylates chromosomal axis component HORMA domain protein HTP-1 to regulate oocyte numbers

Debabrata Das, Shin-Yu Chen, Swathi Arur

Sci Adv. 2020 Oct; 6(44): eabc5580. Published online 2020 Oct 30. doi: 10.1126/sciadv.abc5580

PMCID:: PMC7608811

Abstract Article PDF–13M

Select item 746773015.

Stem cell niche exit in C. elegans via orientation and segregation of daughter cells by a cryptic cell outside the niche

Kacy L Gordon, Jay W Zussman, Xin Li, Camille Miller, David R Sherwood

eLife. 2020; 9: e56383. Published online 2020 Jul 21. doi: 10.7554/eLife.56383

PMCID:: PMC7467730

Abstract Article PDF–11M

Select item 715390116.

GLP-1 Notch—LAG-1 CSL control of the germline stem cell fate is mediated by transcriptional targets lst-1 and sygl-1

Jian Chen, Ariz Mohammad, Nanette Pazdernik, Huiyan Huang, Beth Bowman, Eric Tycksen, Tim Schedl

PLoS Genet. 2020 Mar; 16(3): e1008650. Published online 2020 Mar 20. doi: 10.1371/journal.pgen.1008650

PMCID:: PMC7153901

Abstract Article PDF–3.2M

Select item 713277217.

Distinct roles of two eIF4E isoforms in the germline of Caenorhabditis elegans

Hayden P. Huggins, Jacob S. Subash, Hamilton Stoffel, Melissa A. Henderson, Jenna L. Hoffman, David S. Buckner, Madhu S. Sengupta, Peter R. Boag, Myon-Hee Lee, Brett D. Keiper

J Cell Sci. 2020 Mar 15; 133(6): jcs237990. Published online 2020 Mar 30. doi: 10.1242/jcs.237990