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Select item 108762121.

Organelle proteomic profiling reveals lysosomal heterogeneity in association with longevity

Yong Yu, Shihong M Gao, Youchen Guan, Pei-Wen Hu, Qinghao Zhang, Jiaming Liu, Bentian Jing, Qian Zhao, David M Sabatini, Monther Abu-Remaileh, Sung Yun Jung, Meng C Wang

eLife. 2024; 13: e85214. Published online 2024 Jan 19. doi: 10.7554/eLife.85214

PMCID:: PMC10876212

Abstract Article PDF–5.9M

Select item 108351292.

Amino acid and protein specificity of protein fatty acylation in C. elegans

Bingsen Zhang, Yan Yu, Bennett W. Fox, Yinong Liu, Venkatesh P. Thirumalaikumar, Aleksandra Skirycz, Hening Lin, Frank C. Schroeder

Proc Natl Acad Sci U S A. 2024 Jan 30; 121(5): e2307515121. Published online 2024 Jan 22. doi: 10.1073/pnas.2307515121

PMCID:: PMC10835129

Abstract Article PDF–1.4M

Select item 103490883.

The head mesodermal cell couples FMRFamide neuropeptide signaling with rhythmic muscle contraction in C. elegans

Ukjin Choi, Mingxi Hu, Qixin Zhang, Derek Sieburth

Nat Commun. 2023; 14: 4218. Published online 2023 Jul 14. doi: 10.1038/s41467-023-39955-8

PMCID:: PMC10349088

Abstract Article PDF–2.1M

Select item 94277434.

Adipocytes control food intake and weight regain via Vacuolar-type H⁺ ATPase

Rizaldy C. Zapata, Maria Carretero, Felipe Castellani Gomes Reis, Besma S. Chaudry, Jachelle Ofrecio, Dinghong Zhang, Roman Sasik, Theodore Ciaraldi, Michael Petrascheck, Olivia Osborn

Nat Commun. 2022; 13: 5092. Published online 2022 Aug 30. doi: 10.1038/s41467-022-32764-5

PMCID:: PMC9427743

Abstract Article PDF–2.5M

Select item 91707835.

SGPL1 stimulates VPS39 recruitment to the mitochondria in MICU1 deficient cells

Joshua Jackson, Lena Wischhof, Enzo Scifo, Anna Pellizzer, Yiru Wang, Antonia Piazzesi, Debora Gentile, Sana Siddig, Miriam Stork, Chris E. Hopkins, Kristian Händler, Joachim Weis, Andreas Roos, Joachim L. Schultze, Pierluigi Nicotera, Dan Ehninger, Daniele Bano

Mol Metab. 2022 Jul; 61: 101503. Published online 2022 Apr 19. doi: 10.1016/j.molmet.2022.101503

PMCID:: PMC9170783

Abstract Article PDF–3.7M

Select item 90207166.

A modified TurboID approach identifies tissue-specific centriolar components in C. elegans

Elisabeth Holzer, Cornelia Rumpf-Kienzl, Sebastian Falk, Alexander Dammermann

PLoS Genet. 2022 Apr; 18(4): e1010150. Published online 2022 Apr 20. doi: 10.1371/journal.pgen.1010150

Correction in:: PLoS Genet. 2023 Feb; 19(2): e1010645.

PMCID:: PMC9020716

Abstract Article PDF–2.0M

Select item 86656457.

Variants in ATP6V0A1 cause progressive myoclonus epilepsy and developmental and epileptic encephalopathy

Laura C Bott, Mitra Forouhan, Maria Lieto, Ambre J Sala, Ruth Ellerington, Janel O Johnson, Alfina A Speciale, Chiara Criscuolo, Alessandro Filla, David Chitayat, Ebba Alkhunaizi, Patrick Shannon, Andrea H Nemeth, Italian Undiagnosed Diseases Network , Francesco Angelucci, Wooi Fang Lim, Pasquale Striano, Federico Zara, Ingo Helbig, Mikko Muona, Carolina Courage, Anna-Elina Lehesjoki, Samuel F Berkovic, ATPase Consortium , Kenneth H Fischbeck, Francesco Brancati, Richard I Morimoto, Matthew J A Wood, Carlo Rinaldi

Brain Commun. 2021; 3(4): fcab245. Published online 2021 Oct 18. doi: 10.1093/braincomms/fcab245

PMCID:: PMC8665645

Abstract Article PDF–1.2M

Select item 83311838.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 82630669.

Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences

Xing Zhang, Benjamin W. Harding, Dina Aggad, Damien Courtine, Jia-Xuan Chen, Nathalie Pujol, Jonathan J. Ewbank

PLoS Genet. 2021 Jun; 17(6): e1009600. Published online 2021 Jun 24. doi: 10.1371/journal.pgen.1009600

PMCID:: PMC8263066

Abstract Article PDF–5.0M

Select item 799517610.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 768933911.

Revealing the anticancer potential of candidate drugs in vivo using Caenorhabditis elegans mutant strains

Paul Mark Medina, Jozelle Marie Ponce, Christian Alfredo Cruz

Transl Oncol. 2021 Jan; 14(1): 100940. Published online 2020 Nov 19. doi: 10.1016/j.tranon.2020.100940

PMCID:: PMC7689339

Abstract Article PDF–2.9M

Select item 727478912.

Lysosome activity is modulated by multiple longevity pathways and is important for lifespan extension in C. elegans

Yanan Sun, Meijiao Li, Dongfeng Zhao, Xin Li, Chonglin Yang, Xiaochen Wang

eLife. 2020; 9: e55745. Published online 2020 Jun 2. doi: 10.7554/eLife.55745

PMCID:: PMC7274789

Abstract Article PDF–8.1M

Select item 682614513.

The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans

Stefanie Müthel, Bora Uyar, Mei He, Anne Krause, Burcu Vitrinel, Selman Bulut, Djordje Vasiljevic, Iris Marchal, Stefan Kempa, Altuna Akalin, Baris Tursun

Aging Cell. 2019 Dec; 18(6): e13012. Published online 2019 Aug 9. doi: 10.1111/acel.13012