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Select item 96643601.

Identifying C. elegans lifespan mutants by screening for early-onset protein aggregation

Daniel F. Midkiff, Javier Huayta, James D. Lichty, Joseph P. Crapster, Adriana San-Miguel

iScience. 2022 Nov 18; 25(11): 105460. Published online 2022 Oct 28. doi: 10.1016/j.isci.2022.105460

PMCID:: PMC9664360

Abstract Article PDF–3.6M

Select item 94378482.

Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans

Murat Artan, Markus Hartl, Weiqiang Chen, Mario de Bono

J Biol Chem. 2022 Sep; 298(9): 102343. Published online 2022 Aug 3. doi: 10.1016/j.jbc.2022.102343

PMCID:: PMC9437848

Abstract Article PDF–2.0M

Select item 90207163.

A modified TurboID approach identifies tissue-specific centriolar components in C. elegans

Elisabeth Holzer, Cornelia Rumpf-Kienzl, Sebastian Falk, Alexander Dammermann

PLoS Genet. 2022 Apr; 18(4): e1010150. Published online 2022 Apr 20. doi: 10.1371/journal.pgen.1010150

Correction in:: PLoS Genet. 2023 Feb; 19(2): e1010645.

PMCID:: PMC9020716

Abstract Article PDF–2.0M

Select item 84467934.

Interactome analysis of Caenorhabditis elegans synapses by TurboID-based proximity labeling

Murat Artan, Stephen Barratt, Sean M. Flynn, Farida Begum, Mark Skehel, Armel Nicolas, Mario de Bono

J Biol Chem. 2021 Sep; 297(3): 101094. Published online 2021 Aug 18. doi: 10.1016/j.jbc.2021.101094

Correction in:: J Biol Chem. 2022 Jun; 298(6): 102081.

PMCID:: PMC8446793

Abstract Article PDF–1.6M

Select item 84425755.

Insulin/IGF-1 signaling and heat stress differentially regulate HSF1 activities in germline development

Stacey L. Edwards, Purevsuren Erdenebat, Allison C. Morphis, Lalit Kumar, Lai Wang, Tomasz Chamera, Constantin Georgescu, Jonathan D. Wren, Jian Li

Cell Rep. Author manuscript; available in PMC 2021 Sep 15.

Published in final edited form as: Cell Rep. 2021 Aug 31; 36(9): 109623. doi: 10.1016/j.celrep.2021.109623

PMCID:: PMC8442575

Abstract Article PDF–1.5M

Select item 83311836.

Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus

eLife. 2021; 10: e60833. Published online 2021 Jul 5. doi: 10.7554/eLife.60833

PMCID:: PMC8331183

Abstract Article PDF–8.5M

Select item 81848267.

Autofluorescence as a noninvasive biomarker of senescence and advanced glycation end products in Caenorhabditis elegans

Tomomi Komura, Mikihiro Yamanaka, Kohji Nishimura, Keita Hara, Yoshikazu Nishikawa

NPJ Aging Mech Dis. 2021; 7: 12. Published online 2021 Jun 7. doi: 10.1038/s41514-021-00061-y

PMCID:: PMC8184826

Abstract Article PDF–2.0M

Select item 81669038.

Cryptic genetic variation in a heat shock protein modifies the outcome of a mutation affecting epidermal stem cell development in C. elegans

Sneha L. Koneru, Mark Hintze, Dimitris Katsanos, Michalis Barkoulas

Nat Commun. 2021; 12: 3263. Published online 2021 May 31. doi: 10.1038/s41467-021-23567-1

PMCID:: PMC8166903

Abstract Article PDF–3.9M

Select item 80420059.

The landscape of molecular chaperones across human tissues reveals a layered architecture of core and variable chaperones

Netta Shemesh, Juman Jubran, Shiran Dror, Eyal Simonovsky, Omer Basha, Chanan Argov, Idan Hekselman, Mehtap Abu-Qarn, Ekaterina Vinogradov, Omry Mauer, Tatiana Tiago, Serena Carra, Anat Ben-Zvi, Esti Yeger-Lotem

Nat Commun. 2021; 12: 2180. Published online 2021 Apr 12. doi: 10.1038/s41467-021-22369-9

PMCID:: PMC8042005

Abstract Article PDF–3.3M

Select item 799517610.

EPIC: Software Toolkit for Elution Profile-Based Inference of Protein Complexes

Lucas ZhongMing Hu, Florian Goebels, June H. Tan, Eric Wolf, Uros Kuzmanov, Cuihong Wan, Sadhna Phanse, Changjiang Xu, Mike Schertzberg, Andrew G. Fraser, Gary D. Bader, Andrew Emili

Nat Methods. Author manuscript; available in PMC 2021 Mar 26.

Published in final edited form as: Nat Methods. 2019 Aug; 16(8): 737–742. Published online 2019 Jul 15. doi: 10.1038/s41592-019-0461-4

PMCID:: PMC7995176

Abstract Article PDF–1.0M

Select item 732813211.

Opposing effects of an F-box protein and the HSP90 chaperone network on microtubule stability and neurite growth in Caenorhabditis elegans

Chaogu Zheng, Emily Atlas, Ho Ming Terence Lee, Susan Laura Javier Jao, Ken C. Q. Nguyen, David H. Hall, Martin Chalfie

Development. 2020 Jun 15; 147(12): dev189886. Published online 2020 Jun 17. doi: 10.1242/dev.189886

PMCID:: PMC7328132

Abstract Article

Select item 732749712.

The HSP110/HSP70 disaggregation system generates spreading‐competent toxic α‐synuclein species

Jessica Tittelmeier, Carl Alexander Sandhof, Heidrun Maja Ries, Silke Druffel‐Augustin, Axel Mogk, Bernd Bukau, Carmen Nussbaum‐Krammer

EMBO J. 2020 Jul 1; 39(13): e103954. Published online 2020 May 25. doi: 10.15252/embj.2019103954

PMCID:: PMC7327497

Abstract Article PDF–2.3M

Select item 682614513.

The conserved histone chaperone LIN‐53 is required for normal lifespan and maintenance of muscle integrity in Caenorhabditis elegans

Stefanie Müthel, Bora Uyar, Mei He, Anne Krause, Burcu Vitrinel, Selman Bulut, Djordje Vasiljevic, Iris Marchal, Stefan Kempa, Altuna Akalin, Baris Tursun

Aging Cell. 2019 Dec; 18(6): e13012. Published online 2019 Aug 9. doi: 10.1111/acel.13012

PMCID:: PMC6826145

Abstract Article PDF–3.0M

Select item 621659014.

OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes

Woojin Kim, Ryan S. Underwood, Iva Greenwald, Daniel D. Shaye

Genetics. 2018 Oct; 210(2): 445–461. Published online 2018 Aug 17. doi: 10.1534/genetics.118.301307

PMCID:: PMC6216590

Abstract Article PDF–1.4M

Select item 618855715.

Duplication of hsp-110 Is Implicated in Differential Success of Globodera Species under Climate Change

Laura M Jones, Sebastian Eves-van den Akker, Patricija van-Oosten Hawle, Howard J Atkinson, Peter E Urwin

Mol Biol Evol. 2018 Oct; 35(10): 2401–2413. Published online 2018 Jun 28. doi: 10.1093/molbev/msy132

PMCID:: PMC6188557

Abstract Article PDF–674K

Select item 494261216.

The RNA-binding protein repertoire of Arabidopsis thaliana

Claudius Marondedze, Ludivine Thomas, Natalia L. Serrano, Kathryn S. Lilley, Chris Gehring

Sci Rep. 2016; 6: 29766. Published online 2016 Jul 11. doi: 10.1038/srep29766

PMCID:: PMC4942612

Abstract Article PDF–1.2M

Select item 483047017.

Crucial HSP70 co–chaperone complex unlocks metazoan protein disaggregation

Nadinath B. Nillegoda, Janine Kirstein, Anna Szlachcic, Mykhaylo Berynskyy, Antonia Stank, Florian Stengel, Kristin Arnsburg, Xuechao Gao, Annika Scior, Ruedi Aebersold, D. Lys Guilbride, Rebecca C. Wade, Richard I. Morimoto, Matthias P. Mayer, Bernd Bukau

Nature. Author manuscript; available in PMC 2016 Apr 13.

Published in final edited form as: Nature. 2015 Aug 13; 524(7564): 247–251. Published online 2015 Aug 5. doi: 10.1038/nature14884